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3CU7
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BU of 3cu7 by Molmil
Human Complement Component 5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ...
著者Fredslund, F, Andersen, G.R.
登録日2008-04-16
公開日2008-06-10
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3.105 Å)
主引用文献Structure of and influence of a tick complement inhibitor on human complement component 5
Nat.Immunol., 9, 2008
4F4O
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BU of 4f4o by Molmil
Structure of the Haptoglobin-Haemoglobin Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Haptoglobin, ...
著者Andersen, C.B.F, Torvund-Jensen, M, Nielsen, M.J, Oliveira, C.L.P, Hersleth, H.P, Andersen, N.H, Pedersen, J.S, Andersen, G.R, Moestrup, S.K.
登録日2012-05-11
公開日2012-08-29
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of the haptoglobin-haemoglobin complex.
Nature, 489, 2012
5JPM
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BU of 5jpm by Molmil
Structure of the complex of human complement C4 with MASP-2 rebuilt using iMDFF
分子名称: Complement C4-A, Mannan-binding lectin serine protease 2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Croll, T.I, Andersen, G.R.
登録日2016-05-03
公開日2016-08-10
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.75 Å)
主引用文献Re-evaluation of low-resolution crystal structures via interactive molecular-dynamics flexible fitting (iMDFF): a case study in complement C4.
Acta Crystallogr D Struct Biol, 72, 2016
5JTW
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BU of 5jtw by Molmil
Crystal structure of complement C4b re-refined using iMDFF
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C4-A
著者Croll, T.I, Andersen, G.R.
登録日2016-05-09
公開日2016-08-10
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Re-evaluation of low-resolution crystal structures via interactive molecular-dynamics flexible fitting (iMDFF): a case study in complement C4.
Acta Crystallogr D Struct Biol, 72, 2016
5JPN
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BU of 5jpn by Molmil
Structure of human complement C4 rebuilt using iMDFF
分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C4-A, ...
著者Croll, T.I, Andersen, G.R.
登録日2016-05-03
公開日2016-08-10
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Re-evaluation of low-resolution crystal structures via interactive molecular-dynamics flexible fitting (iMDFF): a case study in complement C4.
Acta Crystallogr D Struct Biol, 72, 2016
8ACI
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BU of 8aci by Molmil
Structure of ARG-117 Fab in complex with a fragment of complement C2, neutral pH
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ARGX-117 Fab heavy chain, ARGX-117 Fab light chain, ...
著者Olesen, H.G, Andersen, G.R.
登録日2022-07-05
公開日2024-01-17
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure-function analysis of ARGX-117, a calcium- and pH-dependent clinical phase complement C2 blocking antibody
To be published
8ACF
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BU of 8acf by Molmil
Structure of the argX-117 in complex with a complement C2 fragment at low pH
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
著者Olesen, H.G, Andersen, G.R.
登録日2022-07-05
公開日2024-01-17
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-function analysis of ARGX-117, a calcium- and pH-dependent clinical phase complement C2 blocking antibody
To be published
4V4B
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BU of 4v4b by Molmil
Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models for RNA and protein components into a 11.7 A cryo-EM map.
分子名称: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S11, ...
著者Spahn, C.M, Gomez-Lorenzo, M.G, Grassucci, R.A, Jorgensen, R, Andersen, G.R, Beckmann, R, Penczek, P.A, Ballesta, J.P.G, Frank, J.
登録日2004-01-06
公開日2014-07-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (11.7 Å)
主引用文献Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation.
Embo J., 23, 2004
3PRX
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BU of 3prx by Molmil
Structure of Complement C5 in Complex with CVF and SSL7
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, ...
著者Laursen, N.S, Andersen, G.R, Sottrup-Jensen, L, Andersen, K.R, Spillner, E, Braren, I.
登録日2010-11-30
公開日2011-01-19
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex.
Embo J., 30, 2011
3PVM
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BU of 3pvm by Molmil
Structure of Complement C5 in Complex with CVF
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, Complement C5
著者Laursen, N.S, Andersen, K.R, Braren, I, Sottrup-Jensen, L, Spillner, E, Andersen, G.R.
登録日2010-12-07
公開日2011-01-19
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex.
Embo J., 30, 2011
3KQ4
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BU of 3kq4 by Molmil
Structure of Intrinsic Factor-Cobalamin bound to its receptor Cubilin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Andersen, C.B.F, Madsen, M, Moestrup, S.K, Andersen, G.R.
登録日2009-11-17
公開日2010-03-09
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis for receptor recognition of vitamin-B(12)-intrinsic factor complexes.
Nature, 464, 2010
6YO6
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BU of 6yo6 by Molmil
Structure of iC3b1
分子名称: hC3Nb1, iC3b1 alpha chain, iC3b1 beta chain
著者Jensen, R.K, Andersen, G.R.
登録日2020-04-14
公開日2021-02-24
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (6 Å)
主引用文献Complement Receptor 3 Forms a Compact High-Affinity Complex with iC3b.
J Immunol., 206, 2021
6Z6V
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BU of 6z6v by Molmil
Globular head of C1q in complex with the nanobody C1qNb75
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, ...
著者Laursen, N.S, Andersen, G.R.
登録日2020-05-29
公開日2020-06-10
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Functional and Structural Characterization of a Potent C1q Inhibitor Targeting the Classical Pathway of the Complement System.
Front Immunol, 11, 2020
1XK9
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BU of 1xk9 by Molmil
Pseudomanas exotoxin A in complex with the PJ34 inhibitor
分子名称: Exotoxin A, N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE
著者Yates, S.P, Taylor, P.J, Joergensen, R, Ferrraris, D, Zhang, J, Andersen, G.R, Merrill, A.R.
登録日2004-09-28
公開日2005-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-function analysis of water-soluble inhibitors of the catalytic domain of exotoxin A from Pseudomonas aeruginosa
BIOCHEM.J., 385, 2005
8CI4
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BU of 8ci4 by Molmil
Crystal structure of doubly S-methanethiolated rabbit M-type creatine kinase
分子名称: CITRATE ANION, Creatine kinase M-type
著者Joergensen, M.H, Andersen, D.G, Andersen, G.R.
登録日2023-02-08
公開日2023-12-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Chemical Zymogens and Transmembrane Activation of Transcription in Synthetic Cells.
Adv Mater, 36, 2024
4WB3
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BU of 4wb3 by Molmil
Crystal structure of the mirror-image L-RNA/L-DNA aptamer NOX-D20 in complex with mouse C5a-desArg complement anaphylatoxin
分子名称: ACETATE ION, CALCIUM ION, Complement C5, ...
著者Yatime, L, Maasch, C, Hoehlig, K, Klussmann, S, Vater, A, Andersen, G.R.
登録日2014-09-02
公開日2015-05-06
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer.
Nat Commun, 6, 2015
4WB2
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BU of 4wb2 by Molmil
Crystal structure of the mirror-image L-RNA/L-DNA aptamer NOX-D20 in complex with mouse C5a complement anaphylatoxin
分子名称: ACETATE ION, CALCIUM ION, Complement C5, ...
著者Yatime, L, Maasch, C, Hoehlig, K, Klussmann, S, Vater, A, Andersen, G.R.
登録日2014-09-02
公開日2015-05-06
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer.
Nat Commun, 6, 2015
7ZMK
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BU of 7zmk by Molmil
Structure of human MFAP4 in complex with the Fab fragment of the AS0326 monoclonal antibody
分子名称: CALCIUM ION, Light chain of AS0326, Microfibril-associated glycoprotein 4, ...
著者Laursen, N.S, Andersen, G.R.
登録日2022-04-19
公開日2023-03-01
最終更新日2025-02-05
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Pharmacological blocking of microfibrillar-associated protein 4 reduces retinal neoangiogenesis and vascular leakage.
Mol.Ther., 2025
2B7B
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BU of 2b7b by Molmil
Yeast guanine nucleotide exchange factor eEF1Balpha K205A mutant in complex with eEF1A and GDP
分子名称: Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE, elongation factor-1 beta
著者Pittman, Y.R, Valente, L, Jeppesen, M.G, Andersen, G.R, Patel, S, Kinzy, T.G.
登録日2005-10-04
公開日2006-05-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Mg2+ and a key lysine modulate exchange activity of eukaryotic translation elongation factor 1B alpha
J.Biol.Chem., 281, 2006
2B7C
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BU of 2b7c by Molmil
Yeast guanine nucleotide exchange factor eEF1Balpha K205A mutant in complex with eEF1A
分子名称: Elongation factor 1-alpha, elongation factor-1 beta
著者Pittman, Y.R, Valente, L, Jeppesen, M.G, Andersen, G.R, Patel, S, Kinzy, T.G.
登録日2005-10-04
公開日2006-05-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mg2+ and a key lysine modulate exchange activity of eukaryotic translation elongation factor 1B alpha
J.Biol.Chem., 281, 2006
2IWH
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BU of 2iwh by Molmil
Structure of yeast Elongation Factor 3 in complex with ADPNP
分子名称: ELONGATION FACTOR 3A, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION
著者Andersen, C.B.F, Becker, T, Blau, M, Anand, M, Halic, M, Balar, B, Mielke, T, Boesen, T, Pedersen, J.S, Spahn, C.M.T, Kinzy, T.G, Andersen, G.R, Beckmann, R.
登録日2006-06-30
公開日2006-08-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of Eef3 and the Mechanism of Transfer RNA Release from the E-Site.
Nature, 443, 2006
2IW3
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BU of 2iw3 by Molmil
Elongation Factor 3 in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ELONGATION FACTOR 3A, SULFATE ION
著者Andersen, C.B.F, Becker, T, Blau, M, Anand, M, Halic, M, Balar, B, Mielke, T, Boesen, T, Pedersen, J.S, Spahn, C.M.T, Kinzy, T.G, Andersen, G.R, Beckmann, R.
登録日2006-06-26
公開日2006-08-17
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of Eef3 and the Mechanism of Transfer RNA Release from the E-Site.
Nature, 443, 2006
2IX3
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BU of 2ix3 by Molmil
Structure of yeast Elongation Factor 3
分子名称: ELONGATION FACTOR 3, SULFATE ION
著者Andersen, C.B.F, Becker, T, Blau, M, Anand, M, Halic, M, Balar, B, Mielke, T, Boesen, T, Pedersen, J.S, Spahn, C.M.T, Kinzy, T.G, Andersen, G.R, Beckmann, R.
登録日2006-07-06
公開日2006-08-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of Eef3 and the Mechanism of Transfer RNA Release from the E-Site.
Nature, 443, 2006
2HYI
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BU of 2hyi by Molmil
Structure of the human exon junction complex with a trapped DEAD-box helicase bound to RNA
分子名称: 5'-R(*UP*UP*UP*UP*UP*U)-3', MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Andersen, C.B.F, Le Hir, H, Andersen, G.R.
登録日2006-08-06
公開日2006-08-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA.
Science, 313, 2006
5NLW
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BU of 5nlw by Molmil
Structure of Nb36 crystal form 2
分子名称: SULFATE ION, nanobody Nb36
著者Hansen, S.B, Andersen, K.R, Laursen, N.S, Andersen, G.R.
登録日2017-04-05
公開日2017-05-31
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Introducing site-specific cysteines into nanobodies for mercury labelling allows de novo phasing of their crystal structures.
Acta Crystallogr D Struct Biol, 73, 2017

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