7ZMK

Structure of human MFAP4 in complex with the Fab fragment of the AS0326 monoclonal antibody

Summary for 7ZMK

• Entry DOI: 10.2210/pdb7zmk/pdb
• Descriptor: Microfibril-associated glycoprotein 4, heavy chain of antibody AS0326, Light chain of AS0326, ... (5 entities in total)
• Functional Keywords: antibody, mfap4, extracellular matrix, cell adhesion
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 24
• Total formula weight: 611836.45

Authors

Laursen, N.S.,Andersen, G.R. (deposition date: 2022-04-19, release date: 2023-03-01, Last modification date: 2024-02-07)

• Primary citation: Pilecki, B.; MFAP4-targeted immunotherapy inhibits retinal neovascularization and vascular leakage; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.4 Å)