6NT8
 
 | | Cryo-EM structure of full-length chicken STING in the cGAMP-bound tetrameric state | | 分子名称: | Stimulator of interferon genes protein, cGAMP | | 著者 | Shang, G, Zhang, C, Chen, Z.J, Bai, X, Zhang, X. | | 登録日 | 2019-01-28 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | | 主引用文献 | Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP.
Nature, 567, 2019
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1KHC
 | | Crystal Structure of the PWWP Domain of Mammalian DNA Methyltransferase Dnmt3b | | 分子名称: | DNA cytosine-5 methyltransferase 3B2, UNKNOWN ATOM OR ION | | 著者 | Qiu, C, Sawada, K, Zhang, X, Cheng, X. | | 登録日 | 2001-11-29 | | 公開日 | 2002-02-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds.
Nat.Struct.Biol., 9, 2002
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7DRV
 | | Structural basis of SARS-CoV-2-closely-related bat coronavirus RaTG13 to hACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | 著者 | Liu, K.F, Pan, X.Q, Li, L.J, Feng, Y, Meng, Y.M, Zhang, Y.F, Wu, L.L, Chen, Q, Zheng, A.Q, Song, C.L, Jia, Y.F, Niu, S, Qiao, C.P, Zhao, X, Ma, D.L, Ma, X.P, Tan, S.G, Qi, J.X, Gao, G.F, Wang, Q.H. | | 登録日 | 2020-12-29 | | 公開日 | 2021-08-25 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | | 主引用文献 | Binding and molecular basis of the bat coronavirus RaTG13 virus to ACE2 in humans and other species.
Cell, 184, 2021
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8AJ8
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6S8F
 | | Structure of nucleotide-bound Tel1/ATM | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1 | | 著者 | Yates, L.A, Williams, R.M, Ayala, R, Zhang, X. | | 登録日 | 2019-07-09 | | 公開日 | 2019-10-30 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Cryo-EM Structure of Nucleotide-Bound Tel1ATMUnravels the Molecular Basis of Inhibition and Structural Rationale for Disease-Associated Mutations.
Structure, 28, 2020
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1DKX
 | | THE SUBSTRATE BINDING DOMAIN OF DNAK IN COMPLEX WITH A SUBSTRATE PEPTIDE, DETERMINED FROM TYPE 1 SELENOMETHIONYL CRYSTALS | | 分子名称: | SUBSTRATE BINDING DOMAIN OF DNAK, SUBSTRATE PEPTIDE (7 RESIDUES) | | 著者 | Zhu, X, Zhao, X, Burkholder, W.F, Gragerov, A, Ogata, C.M, Gottesman, M.E, Hendrickson, W.A. | | 登録日 | 1996-06-03 | | 公開日 | 1996-12-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural analysis of substrate binding by the molecular chaperone DnaK.
Science, 272, 1996
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1DKY
 | | THE SUBSTRATE BINDING DOMAIN OF DNAK IN COMPLEX WITH A SUBSTRATE PEPTIDE, DETERMINED FROM TYPE 2 NATIVE CRYSTALS | | 分子名称: | DNAK, PEPTIDE SUBSTRATE | | 著者 | Zhu, X, Zhao, X, Burkholder, W.F, Gragerov, A, Ogata, C.M, Gottesman, M.E, Hendrickson, W.A. | | 登録日 | 1996-06-03 | | 公開日 | 1996-12-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural analysis of substrate binding by the molecular chaperone DnaK.
Science, 272, 1996
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3KH8
 | | Crystal structure of MaoC-like dehydratase from Phytophthora Capsici | | 分子名称: | MaoC-like dehydratase | | 著者 | Wang, H, Zhang, K, Guo, J, Zhou, Q, Zheng, X, Sun, F, Pang, H, Zhang, X. | | 登録日 | 2009-10-30 | | 公開日 | 2010-11-10 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of MaoC-like dehydratase from Phytophthora Capsici
To be Published
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1JQD
 | | Crystal Structure Analysis of Human Histamine Methyltransferase (Thr105 Polymorphic Variant) Complexed with AdoHcy and Histamine | | 分子名称: | HISTAMINE, Histamine N-Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Horton, J.R, Sawada, K, Nishibori, M, Zhang, X, Cheng, X. | | 登録日 | 2001-08-06 | | 公開日 | 2002-08-06 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons.
Structure, 9, 2001
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1NGN
 | | Mismatch repair in methylated DNA. Structure of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4 | | 分子名称: | methyl-CpG binding protein MBD4 | | 著者 | Wu, P, Qiu, C, Sohail, A, Zhang, X, Bhagwat, A.S, Cheng, X. | | 登録日 | 2002-12-17 | | 公開日 | 2003-03-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Mismatch repair in methylated DNA. Structure and activity of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4
J.Biol.Chem., 278, 2003
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2UXU
 | | TtgR in complex with Naringenin | | 分子名称: | HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGR, NARINGENIN | | 著者 | Alguel, Y, Meng, C, Teran, W, Krell, T, Ramos, J.L, Gallegos, M.-T, Zhang, X. | | 登録日 | 2007-03-29 | | 公開日 | 2007-05-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structures of Multidrug Binding Protein Ttgr in Complex with Antibiotics and Plant Antimicrobials.
J.Mol.Biol., 369, 2007
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2UXO
 | | TtgR in complex with Tetracycline | | 分子名称: | HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGR, TETRACYCLINE | | 著者 | Alguel, Y, Meng, C, Teran, W, Krell, T, Ramos, J.L, Gallegos, M.-T, Zhang, X. | | 登録日 | 2007-03-28 | | 公開日 | 2007-05-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal Structures of Multidrug Binding Protein Ttgr in Complex with Antibiotics and Plant Antimicrobials.
J.Mol.Biol., 369, 2007
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2UXI
 | | Phloretin in complex with TtgR | | 分子名称: | 3-(4-HYDROXYPHENYL)-1-(2,4,6-TRIHYDROXYPHENYL)PROPAN-1-ONE, HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGR | | 著者 | Alguel, Y, Meng, C, Teran, W, Krell, T, Ramos, J.L, Gallegos, M.-T, Zhang, X. | | 登録日 | 2007-03-28 | | 公開日 | 2007-05-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structures of Multidrug Binding Protein Ttgr in Complex with Antibiotics and Plant Antimicrobials.
J.Mol.Biol., 369, 2007
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7CFP
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7CFQ
 | | Crystal structure of WDR5 in complex with H3K4me3Q5ser peptide | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, H3K4me3Q5ser peptide, ... | | 著者 | Zhao, J, Zhang, X, Zang, J. | | 登録日 | 2020-06-27 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural insights into the recognition of histone H3Q5 serotonylation by WDR5.
Sci Adv, 7, 2021
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2UXP
 | | TtgR in complex Chloramphenicol | | 分子名称: | CHLORAMPHENICOL, HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGR | | 著者 | Alguel, Y, Meng, C, Teran, W, Krell, T, Ramos, J.L, Gallegos, M.-T, Zhang, X. | | 登録日 | 2007-03-29 | | 公開日 | 2007-05-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal Structures of Multidrug Binding Protein Ttgr in Complex with Antibiotics and Plant Antimicrobials.
J.Mol.Biol., 369, 2007
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2UXH
 | | TtgR in complex with Quercetin | | 分子名称: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGR | | 著者 | Alguel, Y, Meng, C, Teran, W, Krell, T, Ramos, J.L, Gallegos, M.-T, Zhang, X. | | 登録日 | 2007-03-28 | | 公開日 | 2007-05-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structures of Multidrug Binding Protein Ttgr in Complex with Antibiotics and Plant Antimicrobials.
J.Mol.Biol., 369, 2007
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2W5Q
 | | Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS. | | 分子名称: | 1,2-ETHANEDIOL, MANGANESE (II) ION, PROCESSED GLYCEROL PHOSPHATE LIPOTEICHOIC ACID SYNTHASE | | 著者 | Lu, D, Wormann, M.E, Zhang, X, Scheewind, O, Grundling, A, Freemont, P.S. | | 登録日 | 2008-12-11 | | 公開日 | 2009-02-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structure-Based Mechanism of Lipoteichoic Acid Synthesis by Staphylococcus Aureus Ltas.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2W5T
 | | Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS. | | 分子名称: | (2R)-2,3-dihydroxypropyl phosphate, ACETATE ION, MANGANESE (II) ION, ... | | 著者 | Lu, D, Wormann, M.E, Zhang, X, Schneewind, O, Grundling, A, Freemont, P.S. | | 登録日 | 2008-12-11 | | 公開日 | 2009-02-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure-Based Mechanism of Lipoteichoic Acid Synthesis by Staphylococcus Aureus Ltas.
Proc.Natl.Acad.Sci.USA, 106, 2009
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8QOT
 | | Structure of the mu opioid receptor bound to the antagonist nanobody NbE | | 分子名称: | Anti-Fab Nanobody, Mu-type opioid receptor, NabFab HC, ... | | 著者 | Yu, J, Kumar, A, Zhang, X, Martin, C, Raia, P, Manglik, A, Ballet, S, Boland, A, Stoeber, M. | | 登録日 | 2023-09-29 | | 公開日 | 2023-12-27 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural Basis of mu-Opioid Receptor-Targeting by a Nanobody Antagonist.
Biorxiv, 2023
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2W5R
 | | Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS. | | 分子名称: | (2R)-2,3-dihydroxypropyl phosphate, ACETATE ION, MANGANESE (II) ION, ... | | 著者 | Lu, D, Wormann, M.E, Zhang, X, Schneewind, O, Grundling, A, Freemont, P.S. | | 登録日 | 2008-12-11 | | 公開日 | 2009-02-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure-Based Mechanism of Lipoteichoic Acid Synthesis by Staphylococcus Aureus Ltas.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2W5S
 | | Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS. | | 分子名称: | (2R)-2,3-dihydroxypropyl phosphate, ACETATE ION, MANGANESE (II) ION, ... | | 著者 | Lu, D, Wormann, M.E, Zhang, X, Schneewind, O, Grundling, A, Freemont, P.S. | | 登録日 | 2008-12-11 | | 公開日 | 2009-02-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-Based Mechanism of Lipoteichoic Acid Synthesis by Staphylococcus Aureus Ltas.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2VII
 | | PspF1-275-Mg-AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, PSP OPERON TRANSCRIPTIONAL ACTIVATOR | | 著者 | Joly, N, Rappas, M, Buck, M, Zhang, X. | | 登録日 | 2007-12-04 | | 公開日 | 2008-01-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Trapping of a Transcription Complex Using a New Nucleotide Analogue: AMP Aluminium Fluoride
J.Mol.Biol., 375, 2008
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2WUI
 | | Crystal Structure of MexZ, a key repressor responsible for antibiotic resistance in Pseudomonas aeruginosa. | | 分子名称: | TRANSCRIPTIONAL REGULATOR | | 著者 | Alguel, Y, Lu, D, Quade, N, Zhang, X. | | 登録日 | 2009-10-05 | | 公開日 | 2010-08-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal Structure of Mexz, a Key Repressor Responsible for Antibiotic Resistance in Pseudomonas Aeruginosa.
J.Struct.Biol., 172, 2010
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2XDN
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