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5Y80
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BU of 5y80 by Molmil
Complex structure of cyclin G-associated kinase with gefitinib
分子名称: Cyclin-G-associated kinase, Gefitinib, NANOBODY
著者Ohbayashi, N, Murayama, K, Kato-Murayama, M, Shirouzu, M.
登録日2017-08-18
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for the Inhibition of Cyclin G-Associated Kinase by Gefitinib.
ChemistryOpen, 7, 2018
6O35
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BU of 6o35 by Molmil
Crystal structure of a de novo designed octameric helical-bundle protein
分子名称: de novo designed WSHC8
著者Bick, M.J, Xu, C, Sankaran, B, Baker, D.
登録日2019-02-25
公開日2020-03-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Computational design of transmembrane pores.
Nature, 585, 2020
4IFQ
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BU of 4ifq by Molmil
Crystal structure of Saccharomyces cerevisiae NUP192, residues 2 to 960 [ScNup192(2-960)]
分子名称: IODIDE ION, Nucleoporin NUP192, SULFATE ION
著者Sampathkumar, P, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals)
登録日2012-12-14
公開日2013-02-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structure, dynamics, evolution, and function of a major scaffold component in the nuclear pore complex.
Structure, 21, 2013
6MHJ
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BU of 6mhj by Molmil
Structure of BoNT mutant
分子名称: Botulinum neurotoxin type A, PHOSPHATE ION
著者Lam, K, Jin, R.
登録日2018-09-18
公開日2018-12-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.019 Å)
主引用文献A viral-fusion-peptide-like molecular switch drives membrane insertion of botulinum neurotoxin A1.
Nat Commun, 9, 2018
5X1C
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BU of 5x1c by Molmil
Crystal Structure of Human CRMP-2 without C-terminal Tail
分子名称: Dihydropyrimidinase-related protein 2
著者Nitta, R, Tomabechi, Y, Aoki, M, Shirouzu, M.
登録日2017-01-25
公開日2017-09-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Structural basis for CRMP2-induced axonal microtubule formation
Sci Rep, 7, 2017
5ZJ6
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BU of 5zj6 by Molmil
Crystal structure of HCK kinase complexed with a pyrrolo-pyrimidine inhibitor 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
分子名称: 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Tyrosine-protein kinase HCK
著者Tomabechi, Y, Kukimoto-Niino, M, Shirouzu, M.
登録日2018-03-19
公開日2018-06-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.696 Å)
主引用文献Phosphorylated and non-phosphorylated HCK kinase domains produced by cell-free protein expression.
Protein Expr. Purif., 150, 2018
3QKZ
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BU of 3qkz by Molmil
Crystal structure of mutant His269Arg AKR1B14
分子名称: Aldo-keto reductase family 1, member B7, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Sundaram, K, El-Kabbani, O.
登録日2011-02-02
公開日2012-02-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structure of the His269Arg mutant of the rat aldose reductase-like protein AKR1B14 complexed with NADPH.
Acta Crystallogr.,Sect.F, 68, 2012
6C9U
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BU of 6c9u by Molmil
Crystal structure of [KS3][AT3] didomain from module 3 of 6-deoxyerthronolide B synthase in complex with antibody fragment (Fab)
分子名称: 6-deoxyerythronolide-B synthase EryA2, modules 3 and 4, Heavy chain of Fab 1B2, ...
著者Deis, L.N, Li, X, Mathews, I.I, Khosla, C.
登録日2018-01-28
公開日2018-05-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structure-Function Analysis of the Extended Conformation of a Polyketide Synthase Module.
J. Am. Chem. Soc., 140, 2018
3ANR
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BU of 3anr by Molmil
human DYRK1A/harmine complex
分子名称: 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE, Dual specificity tyrosine-phosphorylation-regulated kinase 1A
著者Nonaka, Y, Hosoya, T, Hagiwara, M, Ito, N.
登録日2010-09-06
公開日2010-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A
Nat Commun, 1, 2010
3ANQ
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BU of 3anq by Molmil
human DYRK1A/inhibitor complex
分子名称: (1Z)-1-(3-ethyl-5-hydroxy-1,3-benzothiazol-2(3H)-ylidene)propan-2-one, Dual specificity tyrosine-phosphorylation-regulated kinase 1A
著者Nonaka, Y, Hosoya, T, Hagiwara, M, Ito, N.
登録日2010-09-06
公開日2010-11-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A
Nat Commun, 1, 2010
7COV
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BU of 7cov by Molmil
Potato D-enzyme, native (substrate free)
分子名称: 4-alpha-glucanotransferase, chloroplastic/amyloplastic, CALCIUM ION, ...
著者Unno, H, Imamura, K.
登録日2020-08-05
公開日2020-08-26
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural analysis and reaction mechanism of the disproportionating enzyme (D-enzyme) from potato.
Protein Sci., 29, 2020
2YVC
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BU of 2yvc by Molmil
Crystal structure of the Radixin FERM domain complexed with the NEP cytoplasmic tail
分子名称: Neprilysin, Radixin
著者Terawaki, S, Kitano, K, Hakoshima, T.
登録日2007-04-11
公開日2007-04-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for type II membrane protein binding by ERM proteins revealed by the radixin-neutral endopeptidase 24.11 (NEP) complex
J.Biol.Chem., 282, 2007
6JPP
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BU of 6jpp by Molmil
Solution structure of ELMO1 RBD
分子名称: Engulfment and cell motility protein 1
著者Tsuda, K, Kukimoto-Niino, M, Shirouzu, M.
登録日2019-03-27
公開日2020-04-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Targeting Ras-binding domain of ELMO1 by computational nanobody design.
Commun Biol, 6, 2023
5AWG
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BU of 5awg by Molmil
Crystal structure of Hg-bound SufB-SufC-SufD complex from Escherichia coli
分子名称: FeS cluster assembly protein SufB, FeS cluster assembly protein SufD, MERCURY (II) ION, ...
著者Hirabayashi, K, Wada, K.
登録日2015-07-03
公開日2015-11-11
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (4.278 Å)
主引用文献Functional Dynamics Revealed by the Structure of the SufBCD Complex, a Novel ATP-binding Cassette (ABC) Protein That Serves as a Scaffold for Iron-Sulfur Cluster Biogenesis
J.Biol.Chem., 290, 2015
1LAW
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BU of 1law by Molmil
STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY CAVITY-FILLING MUTATIONS WITHIN A HYDROPHOBIC CORE
分子名称: RIBONUCLEASE H
著者Ishikawa, K, Nakamura, H, Morikawa, K, Kanaya, S.
登録日1993-05-10
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Stabilization of Escherichia coli ribonuclease HI by cavity-filling mutations within a hydrophobic core.
Biochemistry, 32, 1993
1LAV
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BU of 1lav by Molmil
STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY CAVITY-FILLING MUTATIONS WITHIN A HYDROPHOBIC CORE
分子名称: RIBONUCLEASE H
著者Ishikawa, K, Nakamura, H, Morikawa, K, Kanaya, S.
登録日1993-05-10
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Stabilization of Escherichia coli ribonuclease HI by cavity-filling mutations within a hydrophobic core.
Biochemistry, 32, 1993
5AWF
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BU of 5awf by Molmil
Crystal structure of SufB-SufC-SufD complex from Escherichia coli
分子名称: FeS cluster assembly protein SufB, FeS cluster assembly protein SufD, Probable ATP-dependent transporter SufC
著者Hirabayashi, K, Wada, K.
登録日2015-07-03
公開日2015-11-11
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.957 Å)
主引用文献Functional Dynamics Revealed by the Structure of the SufBCD Complex, a Novel ATP-binding Cassette (ABC) Protein That Serves as a Scaffold for Iron-Sulfur Cluster Biogenesis
J.Biol.Chem., 290, 2015
2Z68
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BU of 2z68 by Molmil
Crystal Structure Of An Artificial Metalloprotein: Cr[N-salicylidene-4-amino-3-hydroxyhydrocinnamic acid]/Wild Type Heme oxygenase
分子名称: Heme oxygenase, SODIUM ION, SULFATE ION, ...
著者Yokoi, N, Unno, M, Ueno, T, Ikeda-Saito, M, Watanabe, Y.
登録日2007-07-24
公開日2007-08-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Ligand design for improvement of thermal stabilityof metal complex/protein hybrids
To be Published
1J19
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BU of 1j19 by Molmil
Crystal structure of the radxin FERM domain complexed with the ICAM-2 cytoplasmic peptide
分子名称: 16-mer peptide from Intercellular adhesion molecule-2, radixin
著者Hamada, K, Shimizu, T, Yonemura, S, Tsukita, S, Tsukita, S, Hakoshima, T.
登録日2002-12-02
公開日2003-03-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex
EMBO J., 22, 2003
4DZO
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BU of 4dzo by Molmil
Structure of Human Mad1 C-terminal Domain Reveals Its Involvement in Kinetochore Targeting
分子名称: Mitotic spindle assembly checkpoint protein MAD1
著者Luo, X, Sun, H, Tomchick, D.R.
登録日2012-03-01
公開日2012-04-11
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structure of human Mad1 C-terminal domain reveals its involvement in kinetochore targeting.
Proc.Natl.Acad.Sci.USA, 109, 2012
3AGG
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BU of 3agg by Molmil
X-ray analysis of lysozyme in the absence of Arg
分子名称: ACETATE ION, CHLORIDE ION, Lysozyme C, ...
著者Ito, L, Shiraki, K, Hasegawa, K, Baba, S, Kumasaka, T.
登録日2010-03-31
公開日2011-03-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献High-resolution X-ray analysis reveals binding of arginine to aromatic residues of lysozyme surface: implication of suppression of protein aggregation by arginine
Protein Eng.Des.Sel., 24, 2011
3AGH
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BU of 3agh by Molmil
X-ray analysis of lysozyme in the presence of 200 mM Arg
分子名称: ACETATE ION, CHLORIDE ION, Lysozyme C, ...
著者Ito, L, Shiraki, K, Hasegawa, K, Baba, S, Kumasaka, T.
登録日2010-03-31
公開日2011-03-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献High-resolution X-ray analysis reveals binding of arginine to aromatic residues of lysozyme surface: implication of suppression of protein aggregation by arginine
Protein Eng.Des.Sel., 24, 2011
4E1B
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BU of 4e1b by Molmil
Re-refinement of PDB entry 2EQA - SUA5 protein from Sulfolobus tokodaii with bound threonylcarbamoyladenylate
分子名称: MAGNESIUM ION, YrdC/Sua5 family protein, threonylcarbamoyladenylate
著者Parthier, C, Goerlich, S, Jaenecke, F, Breithaupt, C, Braeuer, U, Fandrich, U, Clausnitzer, D, Wehmeier, U.F, Boettcher, C, Scheel, D, Stubbs, M.T.
登録日2012-03-06
公開日2012-03-14
最終更新日2012-05-02
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The O-Carbamoyltransferase TobZ Catalyzes an Ancient Enzymatic Reaction.
Angew.Chem.Int.Ed.Engl., 51, 2012
1IUK
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BU of 1iuk by Molmil
The structure of native ID.343 from Thermus thermophilus
分子名称: hypothetical protein TT1466
著者Wada, T, Shirouzu, M, Park, S.-Y, Tame, J.R, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-03-05
公開日2003-07-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of a conserved CoA-binding protein synthesized by a cell-free system.
Acta Crystallogr.,Sect.D, 59, 2003
3AGI
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BU of 3agi by Molmil
High resolution X-ray analysis of Arg-lysozyme complex in the presence of 500 mM Arg
分子名称: ACETATE ION, ARGININE, CHLORIDE ION, ...
著者Ito, L, Shiraki, K, Hasegawa, K, Baba, S, Kumasaka, T.
登録日2010-03-31
公開日2011-03-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献High-resolution X-ray analysis reveals binding of arginine to aromatic residues of lysozyme surface: implication of suppression of protein aggregation by arginine
Protein Eng.Des.Sel., 24, 2011

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