7RWR
 
 | | An RNA aptamer that decreases flavin redox potential | | 分子名称: | FLAVIN MONONUCLEOTIDE, RNA (38-MER) | | 著者 | Gremminger, T, Li, J, Chen, S, Heng, X. | | 登録日 | 2021-08-20 | | 公開日 | 2022-07-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | An RNA aptamer that shifts the reduction potential of metabolic cofactors.
Nat.Chem.Biol., 18, 2022
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7BVG
 | | Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with di-arabinose. | | 分子名称: | 4'-PHOSPHOPANTETHEINE, CALCIUM ION, CARDIOLIPIN, ... | | 著者 | Zhang, L, Zhao, Y, Gao, Y, Wang, Q, Li, J, Besra, G.S, Rao, Z. | | 登録日 | 2020-04-10 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.
Science, 368, 2020
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7SGL
 | | DNA-PK complex of DNA end processing | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA-dependent protein kinase catalytic subunit, Hairpin_1, ... | | 著者 | Liu, L, Li, J, Chen, X, Yang, W, Gellert, M. | | 登録日 | 2021-10-06 | | 公開日 | 2022-01-12 | | 最終更新日 | 2022-01-19 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Autophosphorylation transforms DNA-PK from protecting to processing DNA ends.
Mol.Cell, 82, 2022
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8WF7
 | | The Crystal Structure of integrase from Biortus | | 分子名称: | ACETATE ION, Integrase, SULFATE ION | | 著者 | Wang, F, Cheng, W, Yuan, Z, Qi, J, Li, J. | | 登録日 | 2023-09-19 | | 公開日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | The Crystal Structure of integrase from Biortus
To Be Published
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8X2S
 | | The Crystal Structure of BPGM from Biortus | | 分子名称: | 1,2-ETHANEDIOL, Bisphosphoglycerate mutase | | 著者 | Wang, F, Cheng, W, Yuan, Z, Qi, J, Li, J. | | 登録日 | 2023-11-10 | | 公開日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Crystal Structure of BPGM from Biortus
To Be Published
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8WF4
 | | The Crystal Structure of RSK1 from Biortus. | | 分子名称: | 1,2-ETHANEDIOL, Ribosomal protein S6 kinase alpha-1 | | 著者 | Wang, F, Cheng, W, Lv, Z, Qi, J, Li, J. | | 登録日 | 2023-09-19 | | 公開日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | The Crystal Structure of RSK1 from Biortus.
To Be Published
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6IZQ
 | | PRMT4 bound with a bicyclic compound | | 分子名称: | (2R)-1-(methylamino)-3-(1,3,4,5-tetrahydro-2-benzazepin-2-yl)propan-2-ol, Histone-arginine methyltransferase CARM1 | | 著者 | Xiong, B, Cao, D.Y, Guo, Z.H, Li, Y.L, Li, J, Huang, X, Shen, J.K. | | 登録日 | 2018-12-20 | | 公開日 | 2019-12-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.449 Å) | | 主引用文献 | Design and Synthesis of Potent, Selective Inhibitors of Protein Arginine Methyltransferase 4 against Acute Myeloid Leukemia.
J.Med.Chem., 62, 2019
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5GXO
 | | Discovery of a compound that activates SIRT3 to deacetylate Manganese Superoxide Dismutase | | 分子名称: | MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial | | 著者 | Lu, J, Li, J, Wu, M, Wang, J, Xia, Q. | | 登録日 | 2016-09-19 | | 公開日 | 2017-08-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A small molecule activator of SIRT3 promotes deacetylation and activation of manganese superoxide dismutase.
Free Radic. Biol. Med., 112, 2017
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2LXH
 | | NMR structure of the RING domain in ubiquitin ligase gp78 | | 分子名称: | E3 ubiquitin-protein ligase AMFR, ZINC ION | | 著者 | Das, R, Linag, Y, Mariano, J, Li, J, Huang, T, King, A, Weissman, A, Ji, X, Byrd, R. | | 登録日 | 2012-08-27 | | 公開日 | 2013-08-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine.
Embo J., 32, 2013
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7KQ2
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5ZRX
 | | Crystal Structure of EphA2/SHIP2 Complex | | 分子名称: | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2,Ephrin type-A receptor 2 | | 著者 | Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M. | | 登録日 | 2018-04-25 | | 公開日 | 2018-05-30 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018
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5ZRY
 | | Crystal Structure of EphA6/Odin Complex | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Ankyrin repeat and SAM domain-containing protein 1A,Ephrin type-A receptor 6, ... | | 著者 | Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M. | | 登録日 | 2018-04-25 | | 公開日 | 2018-05-30 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018
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5ZRZ
 | | Crystal Structure of EphA5/SAMD5 Complex | | 分子名称: | Ephrin type-A receptor 5, Sterile alpha motif domain-containing protein 5 | | 著者 | Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M. | | 登録日 | 2018-04-25 | | 公開日 | 2018-05-30 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018
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4ELS
 | | Structure of E. Coli. 1,4-dihydroxy-2- naphthoyl coenzyme A synthases (MENB) in complex with bicarbonate | | 分子名称: | 1,2-ETHANEDIOL, 1,4-Dihydroxy-2-naphthoyl-CoA synthase, BICARBONATE ION, ... | | 著者 | Sun, Y.R, Song, H.G, Li, J, Jiang, M, Li, Y, Zhou, J.H, Guo, Z.H. | | 登録日 | 2012-04-11 | | 公開日 | 2012-06-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | | 主引用文献 | Active site binding and catalytic role of bicarbonate in 1,4-dihydroxy-2-naphthoyl coenzyme A synthases from vitamin K biosynthetic pathways
Biochemistry, 51, 2012
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4CKH
 | | Helical reconstruction of ACAP1(BAR-PH domain) decorated membrane tubules by cryo-electron microscopy | | 分子名称: | ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 | | 著者 | Pang, X.Y, Fan, J, Zhang, Y, Zhang, K, Gao, B.Q, Ma, J, Li, J, Deng, Y.C, Zhou, Q.J, Hsu, V, Sun, F. | | 登録日 | 2014-01-06 | | 公開日 | 2014-10-15 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (17 Å) | | 主引用文献 | A Ph Domain in Acap1 Possesses Key Features of the Bar Domain in Promoting Membrane Curvature.
Dev.Cell, 31, 2014
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4CKG
 | | Helical reconstruction of ACAP1(BAR-PH domain) decorated membrane tubules by cryo-electron microscopy | | 分子名称: | ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 | | 著者 | Pang, X.Y, Fan, J, Zhang, Y, Zhang, K, Gao, B.Q, Ma, J, Li, J, Deng, Y.C, Zhou, Q.J, Hsu, V, Sun, F. | | 登録日 | 2014-01-06 | | 公開日 | 2014-10-15 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (15 Å) | | 主引用文献 | A Ph Domain in Acap1 Possesses Key Features of the Bar Domain in Promoting Membrane Curvature.
Dev.Cell, 31, 2014
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5WQT
 | | Structure of a protein involved in pyroptosis | | 分子名称: | CITRIC ACID, GLYCEROL, Gasdermin-D | | 著者 | Kuang, S, Li, J. | | 登録日 | 2016-11-28 | | 公開日 | 2017-10-04 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Structure insight of GSDMD reveals the basis of GSDMD autoinhibition in cell pyroptosis.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4ELX
 | | Structure of apo E.coli. 1,4-dihydroxy-2- naphthoyl CoA synthases with Cl | | 分子名称: | 1,2-ETHANEDIOL, 1,4-Dihydroxy-2-naphthoyl-CoA synthase, CHLORIDE ION, ... | | 著者 | Sun, Y.R, Song, H.G, Li, J, Jiang, M, Li, Y, Zhou, J.H, Guo, Z.H. | | 登録日 | 2012-04-11 | | 公開日 | 2012-06-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.191 Å) | | 主引用文献 | Active site binding and catalytic role of bicarbonate in 1,4-dihydroxy-2-naphthoyl coenzyme A synthases from vitamin K biosynthetic pathways
Biochemistry, 51, 2012
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3KAY
 | | Crystal structure of abscisic acid receptor PYL1 | | 分子名称: | Putative uncharacterized protein At5g46790 | | 著者 | Zhou, X.E, Melcher, K, Ng, L.-M, Soon, F.-F, Xu, Y, Suino-Powell, K.M, Kovach, A, Li, J, Xu, H.E. | | 登録日 | 2009-10-19 | | 公開日 | 2009-12-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
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3KB0
 | | Crystal structure of abscisic acid-bound PYL2 | | 分子名称: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Putative uncharacterized protein At2g26040 | | 著者 | Zhou, X.E, Melcher, K, Ng, L.-M, Soon, F.-F, Xu, Y, Suino-Powell, K.M, Kovach, A, Li, J, Xu, H.E. | | 登録日 | 2009-10-19 | | 公開日 | 2009-12-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
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3KAZ
 | | Crystal structure of abscisic acid receptor PYL2 | | 分子名称: | 1,3-BUTANEDIOL, Putative uncharacterized protein At2g26040 | | 著者 | Zhou, X.E, Melcher, K, Ng, L.-M, Soon, F.-F, Xu, Y, Suino-Powell, K.M, Kovach, A, Li, J, Xu, H.E. | | 登録日 | 2009-10-19 | | 公開日 | 2009-12-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
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2LXP
 | | NMR structure of two domains in ubiquitin ligase gp78, RING and G2BR, bound to its conjugating enzyme Ube2g | | 分子名称: | E3 ubiquitin-protein ligase AMFR, Ubiquitin-conjugating enzyme E2 G2, ZINC ION | | 著者 | Das, R, Linag, Y, Mariano, J, Li, J, Huang, T, King, A, Weissman, A, Ji, X, Byrd, R. | | 登録日 | 2012-08-30 | | 公開日 | 2013-08-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine.
Embo J., 32, 2013
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5XF7
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4G5R
 | | Structure of LGN GL4/Galphai3 complex | | 分子名称: | CITRIC ACID, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Jia, M, Li, J, Zhu, J, Wen, W, Zhang, M, Wang, W. | | 登録日 | 2012-07-18 | | 公開日 | 2012-09-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.481 Å) | | 主引用文献 | Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
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4G5O
 | | Structure of LGN GL4/Galphai3(Q147L) complex | | 分子名称: | CITRIC ACID, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Jia, M, Li, J, Zhu, J, Wen, W, Zhang, M, Wang, W. | | 登録日 | 2012-07-18 | | 公開日 | 2012-09-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
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