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2RJE
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BU of 2rje by Molmil
Crystal structure of L3MBTL1 in complex with H4K20Me2 (residues 17-25), orthorhombic form II
分子名称: CHLORIDE ION, Histone H4, Lethal(3)malignant brain tumor-like protein
著者Allali-Hassani, A, Liu, Y, Herzanych, N, Ouyang, H, Mackenzie, F, Crombet, L, Loppnau, P, Kozieradzki, I, Vedadi, M, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J.R, Structural Genomics Consortium (SGC)
登録日2007-10-14
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献L3MBTL1 recognition of mono- and dimethylated histones.
Nat.Struct.Mol.Biol., 14, 2007
3MTS
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BU of 3mts by Molmil
Chromo Domain of Human Histone-Lysine N-Methyltransferase SUV39H1
分子名称: Histone-lysine N-methyltransferase SUV39H1
著者Lam, R, Li, Z, Wang, J, Crombet, L, Walker, J.R, Ouyang, H, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2010-04-30
公開日2010-06-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the Human SUV39H1 Chromodomain and Its Recognition of Histone H3K9me2/3.
Plos One, 7, 2012
2PQW
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BU of 2pqw by Molmil
Crystal structure of L3MBTL1 in complex with H4K20Me2 (residues 17-25), trigonal form
分子名称: ACETATE ION, Histone H4, Lethal(3)malignant brain tumor-like protein
著者Allali-Hassani, A, Liu, Y, Herzanych, N, Ouyang, H, Mackenzie, F, Crombet, L, Loppnau, P, Kozieradzki, I, Vedadi, M, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J.R, Structural Genomics Consortium (SGC)
登録日2007-05-02
公開日2007-07-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献L3MBTL1 recognition of mono- and dimethylated histones.
Nat.Struct.Mol.Biol., 14, 2007
4E47
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BU of 4e47 by Molmil
SET7/9 in complex with inhibitor (R)-(3-(3-cyanophenyl)-1-oxo-1-(pyrrolidin-1-yl)propan-2-yl)-1,2,3,4-tetrahydroisoquinoline-6- sulfonamide and S-adenosylmethionine
分子名称: (R)-(3-(3-cyanophenyl)-1-oxo-1-(pyrrolidin-1-yl)propan-2-yl)-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide, BETA-MERCAPTOETHANOL, Histone-lysine N-methyltransferase SETD7, ...
著者Walker, J.R, Ouyang, H, Dong, A, Fish, P, Cook, A, Barsyte, D, Vedadi, M, Tatlock, J, Owen, D, Bunnage, M, Bountra, C, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Brown, P.J, Structural Genomics Consortium (SGC)
登録日2012-03-12
公開日2012-03-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Setd7 in Complex with Inhibitor and SAM
To be Published
3F2U
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BU of 3f2u by Molmil
Crystal structure of human chromobox homolog 1 (CBX1)
分子名称: Chromobox protein homolog 1
著者Amaya, M.F, Ravichandran, M, Tempel, W, Wernimont, A.K, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Botchkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2008-10-30
公開日2008-11-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the complex of human chromobox homolog 1 (CBX1)
To be Published
3I91
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BU of 3i91 by Molmil
Crystal structure of human chromobox homolog 8 (CBX8) with H3K9 peptide
分子名称: Chromobox protein homolog 8, H3K9 peptide
著者Amaya, M.F, Ravichandran, M, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2009-07-10
公開日2009-09-08
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Recognition and specificity determinants of the human cbx chromodomains.
J.Biol.Chem., 286, 2011
3I8Z
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BU of 3i8z by Molmil
Crystal structure of human chromobox homolog 4 (CBX4)
分子名称: E3 SUMO-protein ligase CBX4
著者Amaya, M.F, Zhihong, L, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2009-07-10
公開日2009-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Crystal structure of human chromobox homolog 4 (CBX4)
To be Published
3I90
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BU of 3i90 by Molmil
Crystal structure of human chromobox homolog 6 (CBX6) with H3K27 peptide
分子名称: Chromobox protein homolog 6, H3K27 peptide
著者Amaya, M.F, Ravichandran, M, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2009-07-10
公開日2009-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Recognition and specificity determinants of the human cbx chromodomains.
J.Biol.Chem., 286, 2011
3FDT
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BU of 3fdt by Molmil
Crystal structure of the complex of human chromobox homolog 5 (CBX5) with H3K9(me)3 peptide
分子名称: Chromobox protein homolog 5, H3K9(me)3 peptide
著者Amaya, M.F, Ravichandran, M, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2008-11-26
公開日2009-01-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Recognition and specificity determinants of the human cbx chromodomains.
J.Biol.Chem., 286, 2011
3H91
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BU of 3h91 by Molmil
Crystal structure of the complex of human chromobox homolog 2 (CBX2) and H3K27 peptide
分子名称: Chromobox protein homolog 2, H3K27 peptide
著者Amaya, M.F, Ravichandran, M, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2009-04-29
公開日2009-08-18
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Recognition and specificity determinants of the human cbx chromodomains.
J.Biol.Chem., 286, 2011
3I3C
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BU of 3i3c by Molmil
Crystal Structural of CBX5 Chromo Shadow Domain
分子名称: Chromobox protein homolog 5, SODIUM ION
著者Amaya, M.F, Li, Z, Li, Y, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2009-06-30
公開日2009-08-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Crystal Structural of CBX5 Chromo Shadow Domain
To be Published
3GV6
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BU of 3gv6 by Molmil
Crystal Structure of human chromobox homolog 6 (CBX6) with H3K9 peptide
分子名称: Chromobox protein homolog 6, Histone H3K9me3 peptide
著者Dong, A, Amaya, M.F, Li, Z, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2009-03-30
公開日2009-04-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Recognition and specificity determinants of the human cbx chromodomains.
J.Biol.Chem., 286, 2011
3GV4
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BU of 3gv4 by Molmil
Crystal structure of human HDAC6 zinc finger domain and ubiquitin C-terminal peptide RLRGG
分子名称: CALCIUM ION, Histone deacetylase 6, ZINC ION, ...
著者Dong, A, Ravichandran, M, Loppnau, P, Li, Y, MacKenzie, F, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Dhe-Paganon, S, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2009-03-30
公開日2009-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Crystal structure of human HDAC6 zinc finger domain and ubiquitin C-terminal peptide RLRGG
To be Published
2KEO
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BU of 2keo by Molmil
Solution NMR structure of human protein HS00059, cytochrome-b5-like domain of the HERC2 E3 ligase. Northeast structural genomics consortium (NESG) target ht98a
分子名称: Probable E3 ubiquitin-protein ligase HERC2
著者Lemak, A, Gutmanas, A, Fares, C, Quyang, H, Li, Y, Montelione, G, Arrowsmith, C, Dhe-Paganon, S, Northeast Structural Genomics Consortium (NESG)
登録日2009-01-30
公開日2009-02-24
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of human protein HS00059
To be Published
2K28
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BU of 2k28 by Molmil
Solution NMR structure of the chromo domain of the chromobox protein homolog 4
分子名称: E3 SUMO-protein ligase CBX4
著者Kaustov, L, Lemak, A, Quyang, H, Fares, C, Gutmanas, A, Ravichandran, M, Loppnau, P, Bountra, C, Weigelt, J, Edwards, A.M, Min, J, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
登録日2008-03-27
公開日2008-04-08
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution NMR structure of the chromo domain of the chromobox protein homolog 4.
To be Published
2K1B
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BU of 2k1b by Molmil
Solution NMR structure of the chromo domain of the chromobox protein homolog 7
分子名称: Chromobox protein homolog 7
著者Kaustov, L, Lemak, A, Quyang, H, Gutmanas, A, Fares, C, Bountra, C, Weigelt, J, Loppnau, P, Ravichandran, M, Edwards, A.M, Min, J, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
登録日2008-02-25
公開日2008-03-11
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution NMR structure of the chromobox protein homolog 7.
To be Published
7XYF
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BU of 7xyf by Molmil
Cryo-EM structure of Fft3-nucleosome complex with Fft3 bound to SHL+2 position of the nucleosome
分子名称: ATP-dependent helicase fft3, DNA (167-MER), Histone H2A, ...
著者Nan, Z, Tao, J, Yangao, H.
登録日2022-06-01
公開日2023-12-06
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structure of Fft3-nucleosome complex with Fft3 bound to SHL+2 position of the nucleosome (Class I Fft3-nucleosome complex)
To Be Published
7XYG
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BU of 7xyg by Molmil
Cryo-EM structure of Fft3-nucleosome complex with Fft3 bound to SHL+3 position of the nucleosome
分子名称: ATP-dependent helicase fft3, DNA (167-MER), Histone H2A, ...
著者Nan, Z, Tao, J, Yangao, H.
登録日2022-06-01
公開日2023-12-06
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM structure of Fft3-nucleosome complex with Fft3 bound to SHL+3 position of the nucleosome (Class II Fft3-nucleosome complex)
To Be Published
7XXE
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BU of 7xxe by Molmil
Crystal structure of spFft3 C-terminal truncation
分子名称: ATP-dependent helicase fft3
著者Nan, Z, Tao, J, Yangao, H.
登録日2022-05-30
公開日2023-12-06
実験手法X-RAY DIFFRACTION (4.202 Å)
主引用文献Crystal structure of spFft3 C-terminal truncation
To Be Published
1IYJ
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BU of 1iyj by Molmil
STRUCTURE OF A BRCA2-DSS1 COMPLEX
分子名称: Deleted in split hand/split foot protein 1, breast cancer susceptibility
著者Pavletich, N.P, Jeffrey, P.D, Yang, H.J.
登録日2002-08-28
公開日2002-10-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure.
Science, 297, 2002
6P3X
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BU of 6p3x by Molmil
Crystal Structure of Full Length APOBEC3G E/Q (pH 7.0)
分子名称: Apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G, ZINC ION
著者Yang, H.J, Li, S.X, Chen, X.S.
登録日2019-05-25
公開日2020-02-12
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Understanding the structural basis of HIV-1 restriction by the full length double-domain APOBEC3G.
Nat Commun, 11, 2020
6P3Z
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Crystal Structure of Full Length APOBEC3G E/Q (pH 5.2)
分子名称: Apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G, ZINC ION
著者Yang, H.J, Li, S.X, Chen, X.S.
登録日2019-05-25
公開日2020-02-12
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.844 Å)
主引用文献Understanding the structural basis of HIV-1 restriction by the full length double-domain APOBEC3G.
Nat Commun, 11, 2020
6P3Y
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Crystal Structure of Full Length APOBEC3G E/Q (pH 7.4)
分子名称: Apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G, ZINC ION
著者Yang, H.J, Li, S.X, Chen, X.S.
登録日2019-05-25
公開日2020-02-12
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Understanding the structural basis of HIV-1 restriction by the full length double-domain APOBEC3G.
Nat Commun, 11, 2020
6P40
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Crystal Structure of Full Length APOBEC3G FKL
分子名称: Apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G, ZINC ION
著者Yang, H.J, Li, S.X, Chen, X.S.
登録日2019-05-25
公開日2020-02-12
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.452 Å)
主引用文献Understanding the structural basis of HIV-1 restriction by the full length double-domain APOBEC3G.
Nat Commun, 11, 2020
3MF5
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Hepatitis C virus polymerase NS5B (BK) with amide bioisostere thumb site inhibitor
分子名称: 3-[2-(trans-4-methylcyclohexyl)phenyl]-5-phenylthiophene-2-carboxylic acid, GLYCEROL, RNA-directed RNA polymerase
著者Harris, S.F, Tavares, G, Ghate, M.
登録日2010-04-01
公開日2010-07-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cyclic amide bioisosterism: Strategic application to the design and synthesis of HCV NS5B polymerase inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010

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