2JX1
 
 | | Structure of the fifth zinc finger of Myelin Transcription Factor 1 in complex with RARE DNA | | 分子名称: | DNA (5'-D(*DAP*DCP*DCP*DGP*DAP*DAP*DAP*DGP*DTP*DTP*DCP*DAP*DC)-3'), DNA (5'-D(*DGP*DTP*DGP*DAP*DAP*DCP*DTP*DTP*DTP*DCP*DGP*DGP*DT)-3'), Myelin transcription factor 1 | | 著者 | Gamsjaeger, R, Swanton, M.K, Kobus, F.J, Lehtomaki, E, Lowry, J.A, Kwan, A.H, Matthews, J.M, Mackay, J.P. | | 登録日 | 2007-11-01 | | 公開日 | 2007-12-11 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the fifth zinc finger of Myelin Transcription Factor 1 in complex with RARE DNA
To be Published
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1SNU
 | | CRYSTAL STRUCTURE OF THE UNPHOSPHORYLATED INTERLEUKIN-2 TYROSINE KINASE CATALYTIC DOMAIN | | 分子名称: | STAUROSPORINE, Tyrosine-protein kinase ITK/TSK | | 著者 | Brown, K, Long, J.M, Vial, S.C, Dedi, N, Dunster, N.J, Renwick, S.B, Tanner, A.J, Frantz, J.D, Fleming, M.A, Cheetham, G.M.T. | | 登録日 | 2004-03-12 | | 公開日 | 2004-07-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of interleukin-2 tyrosine kinase and their implications for the design of selective inhibitors.
J.Biol.Chem., 279, 2004
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1SJ2
 | | Crystal structure of Mycobacterium tuberculosis catalase-peroxidase | | 分子名称: | GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, Peroxidase/catalase T | | 著者 | Bertrand, T, Eady, N.A.J, Jones, J.N, Bodiguel, J, Jesmin, Nagy, J.M, Raven, E.L, Jamart-Gregoire, B, Brown, K.A. | | 登録日 | 2004-03-02 | | 公開日 | 2004-07-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Crystal Structure of Mycobacterium tuberculosis Catalase-Peroxidase.
J.Biol.Chem., 279, 2004
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2K3A
 | | NMR solution structure of Staphylococcus saprophyticus CHAP (cysteine, histidine-dependent amidohydrolases/peptidases) domain protein. Northeast Structural Genomics Consortium target SyR11 | | 分子名称: | CHAP domain protein | | 著者 | Rossi, P, Aramini, J.M, Chen, C.X, Nwosu, C, Cunningham, K.C, Owens, L.A, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2008-04-29 | | 公開日 | 2008-05-13 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural elucidation of the Cys-His-Glu-Asn proteolytic relay in the secreted CHAP domain enzyme from the human pathogen Staphylococcus saprophyticus.
Proteins, 74, 2008
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1SDU
 | | Crystal structures of HIV protease V82A and L90M mutants reveal changes in indinavir binding site. | | 分子名称: | ACETATE ION, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE, SULFATE ION, ... | | 著者 | Mahalingam, B, Wang, Y.-F, Boross, P.I, Tozser, J, Louis, J.M, Harrison, R.W, Weber, I.T. | | 登録日 | 2004-02-14 | | 公開日 | 2004-05-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Crystal structures of HIV protease V82A and L90M
mutants reveal changes in the indinavir-binding site
Eur.J.Biochem., 271, 2004
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1SFE
 | | ADA O6-METHYLGUANINE-DNA METHYLTRANSFERASE FROM ESCHERICHIA COLI | | 分子名称: | ADA O6-METHYLGUANINE-DNA METHYLTRANSFERASE | | 著者 | Moore, M.H, Gulbis, J.M, Dodson, E.J, Demple, B, Moody, P.C.E. | | 登録日 | 1996-06-21 | | 公開日 | 1996-12-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of a suicidal DNA repair protein: the Ada O6-methylguanine-DNA methyltransferase from E. coli.
EMBO J., 13, 1994
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1AJJ
 | | LDL RECEPTOR LIGAND-BINDING MODULE 5, CALCIUM-COORDINATING | | 分子名称: | CALCIUM ION, LOW-DENSITY LIPOPROTEIN RECEPTOR, SULFATE ION | | 著者 | Fass, D, Blacklow, S.C, Kim, P.S, Berger, J.M. | | 登録日 | 1997-05-04 | | 公開日 | 1997-07-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module.
Nature, 388, 1997
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1SH3
 | | Crystal Structure of Norwalk Virus Polymerase (MgSO4 crystal form) | | 分子名称: | MAGNESIUM ION, RNA Polymerase | | 著者 | Ng, K.K, Pendas-Franco, N, Rojo, J, Boga, J.A, Machin, A, Alonso, J.M, Parra, F. | | 登録日 | 2004-02-24 | | 公開日 | 2004-03-09 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Crystal structure of norwalk virus polymerase reveals the carboxyl terminus in the active site cleft.
J.Biol.Chem., 279, 2004
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1SDT
 | | Crystal structures of HIV protease V82A and L90M mutants reveal changes in indinavir binding site. | | 分子名称: | CHLORIDE ION, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE, protease RETROPEPSIN | | 著者 | Mahalingam, B, Wang, Y.-F, Boross, P.I, Tozser, J, Louis, J.M, Harrison, R.W, Weber, I.T. | | 登録日 | 2004-02-14 | | 公開日 | 2004-05-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Crystal structures of HIV protease V82A and L90M
mutants reveal changes in the indinavir-binding site
Eur.J.Biochem., 271, 2004
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2JP8
 | | Angiotensin 1-7 | | 分子名称: | Angiotensin-(1-7) | | 著者 | Lula, I, Denadai, A.L, Resende, J.M, de Souza, F.B, de Lima, G.F, Pilo-Veloso, D, Heine, T, Duarte, H.A, Santos, R.A.S, Sinesterra, R.D. | | 登録日 | 2007-04-27 | | 公開日 | 2007-10-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Study of angiotensin-(1-7) vasoactive peptide and its beta-cyclodextrin inclusion complexes: complete sequence-specific NMR assignments and structural studies
Peptides, 28, 2007
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1TVA
 | | HUMAN DNA POLYMERASE BETA COMPLEXED WITH NICKED DNA CONTAINING A MISMATCHED TEMPLATE THYMIDINE AND INCOMING CYTIDINE | | 分子名称: | 5'-D(*CP*CP*GP*AP*CP*TP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | | 著者 | Krahn, J.M, Beard, W.A, Wilson, S.H. | | 登録日 | 2004-06-29 | | 公開日 | 2004-11-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural insights into DNA polymerase Beta deterrents for misincorporation support an induced-fit mechanism for fidelity
Structure, 12, 2004
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1U2N
 | | Structure CBP TAZ1 Domain | | 分子名称: | CREB binding protein, ZINC ION | | 著者 | De Guzman, R.N, Wojciak, J.M, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | | 登録日 | 2004-07-19 | | 公開日 | 2005-04-26 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding
Biochemistry, 44, 2005
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2J5C
 | | Rational conversion of substrate and product specificity in a monoterpene synthase. Structural insights into the molecular basis of rapid evolution. | | 分子名称: | 1,8-CINEOLE SYNTHASE, BETA-MERCAPTOETHANOL | | 著者 | Kampranis, S.C, Ioannidis, D, Purvis, A, Mahrez, W, Ninga, E, Katerelos, N.A, Anssour, S, Dunwell, J.M, Makris, A.M, Goodenough, P.W, Johnson, C.B. | | 登録日 | 2006-09-14 | | 公開日 | 2007-06-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Rational Conversion of Substrate and Product Specificity in a Salvia Monoterpene Synthase: Structural Insights Into the Evolution of Terpene Synthase Function.
Plant Cell, 19, 2007
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2IWN
 | | 3rd PDZ domain of Multiple PDZ Domain Protein MPDZ | | 分子名称: | MULTIPLE PDZ DOMAIN PROTEIN | | 著者 | Elkins, J.M, Gileadi, C, Savitsky, P, Berridge, G, Smee, C.E.A, Pike, A.C.W, Papagrigoriou, E, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, Doyle, D.A. | | 登録日 | 2006-07-03 | | 公開日 | 2006-07-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structure of Pick1 and Other Pdz Domains Obtained with the Help of Self-Binding C-Terminal Extension.
Protein Sci., 16, 2007
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1A30
 | | HIV-1 PROTEASE COMPLEXED WITH A TRIPEPTIDE INHIBITOR | | 分子名称: | HIV-1 PROTEASE, TRIPEPTIDE GLU-ASP-LEU | | 著者 | Louis, J.M, Dyda, F, Nashed, N.T, Kimmel, A.R, Davies, D.R. | | 登録日 | 1998-01-27 | | 公開日 | 1998-04-29 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Hydrophilic peptides derived from the transframe region of Gag-Pol inhibit the HIV-1 protease.
Biochemistry, 37, 1998
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2J5B
 | | Structure of the Tyrosyl tRNA synthetase from Acanthamoeba polyphaga Mimivirus complexed with tyrosynol | | 分子名称: | 4-[(2S)-2-amino-3-hydroxypropyl]phenol, TYROSYL-TRNA SYNTHETASE | | 著者 | Abergel, C, Rudinger-thirion, J, Giege, R, Claverie, J.M. | | 登録日 | 2006-09-13 | | 公開日 | 2007-09-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Virus-Encoded Aminoacyl-tRNA Synthetases: Structural and Functional Characterization of Mimivirus Tyrrs and Metrs.
J.Virol., 81, 2007
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1A8K
 | | CRYSTALLOGRAPHIC ANALYSIS OF HUMAN IMMUNODEFICIENCY VIRUS 1 PROTEASE WITH AN ANALOG OF THE CONSERVED CA-P2 SUBSTRATE: INTERACTIONS WITH FREQUENTLY OCCURRING GLUTAMIC ACID RESIDUE AT P2' POSITION OF SUBSTRATES | | 分子名称: | HIV PROTEASE, N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide | | 著者 | Weber, I.T, Wu, J, Adomat, J, Harrison, R.W, Kimmel, A.R, Wondrak, E.M, Louis, J.M. | | 登録日 | 1998-03-27 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystallographic analysis of human immunodeficiency virus 1 protease with an analog of the conserved CA-p2 substrate -- interactions with frequently occurring glutamic acid residue at P2' position of substrates.
Eur.J.Biochem., 249, 1997
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1TZY
 | | Crystal Structure of the Core-Histone Octamer to 1.90 Angstrom Resolution | | 分子名称: | CHLORIDE ION, HISTONE H3, HISTONE H4-VI, ... | | 著者 | Wood, C.M, Nicholson, J.M, Chantalat, L, Reynolds, C.D, Lambert, S.J, Baldwin, J.P. | | 登録日 | 2004-07-12 | | 公開日 | 2004-08-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | High-resolution structure of the native histone octamer.
Acta Crystallogr.,Sect.F, 61, 2005
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2IVJ
 | | Isopenicillin N Synthase From Aspergillus Nidulans (Anaerobic Ac- cyclopropylglycine Fe Complex) | | 分子名称: | D-(L-A-AMINOADIPOYL)-L-CYSTEINYL-D-CYCLOPROPYLGLYCINE, FE (II) ION, ISOPENICILLIN N SYNTHETASE, ... | | 著者 | Howard-Jones, A.R, Elkins, J.M, Clifton, I.J, Roach, P.L, Adlington, R.M, Baldwin, J.E, Rutledge, P.J. | | 登録日 | 2006-06-13 | | 公開日 | 2007-04-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Interactions of Isopenicillin N Synthase with Cyclopropyl-Containing Substrate Analogues Reveal New Mechanistic Insight.
Biochemistry, 46, 2007
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1TXY
 | | E. coli PriB | | 分子名称: | Primosomal replication protein n | | 著者 | Keck, J.L, Lopper, M, Holton, J.M. | | 登録日 | 2004-07-06 | | 公開日 | 2004-11-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of PriB, a component of the Escherichia coli replication restart primosome
Structure, 12, 2004
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1S0M
 | | Crystal structure of a Benzo[a]pyrene Diol Epoxide adduct in a ternary complex with a DNA polymerase | | 分子名称: | 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*T)-3', ... | | 著者 | Ling, H, Sayer, J.M, Boudsocq, F, Plosky, B.S, Woodgate, R, Yang, W. | | 登録日 | 2003-12-31 | | 公開日 | 2004-03-30 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase.
Proc.Natl.Acad.Sci.USA, 101, 2004
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1S19
 | | Crystal structure of VDR ligand binding domain complexed to calcipotriol. | | 分子名称: | CALCIPOTRIOL, Vitamin D3 receptor | | 著者 | Tocchini-Valentini, G, Rochel, N, Wurtz, J.M, Moras, D. | | 登録日 | 2004-01-06 | | 公開日 | 2004-04-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification.
J.Med.Chem., 47, 2004
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2IWQ
 | | 7th PDZ domain of Multiple PDZ Domain Protein MPDZ | | 分子名称: | MULTIPLE PDZ DOMAIN PROTEIN | | 著者 | Elkins, J.M, Berridge, G, Savitsky, P, Smee, C.E.A, Turnbull, A, Ugochukwu, E, Papagrigoriou, E, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, Doyle, D.A. | | 登録日 | 2006-07-03 | | 公開日 | 2006-07-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of Pick1 and Other Pdz Domains Obtained with the Help of Self-Binding C-Terminal Extensions.
Protein Sci., 16, 2007
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1S49
 | | Crystal Structure of RNA-dependent RNA polymerase construct 1 (residues 71-679) from bovine viral diarrhea virus complexed with GTP | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, RNA-dependent RNA polymerase | | 著者 | Choi, K.H, Groarke, J.M, Young, D.C, Kuhn, R.J, Smith, J.L, Pevear, D.C, Rossmann, M.G. | | 登録日 | 2004-01-15 | | 公開日 | 2004-04-06 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation.
Proc.Natl.Acad.Sci.Usa, 101, 2004
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1S0T
 | | Solution structure of a DNA duplex containing an alpha-anomeric adenosine: insights into substrate recognition by endonuclease IV | | 分子名称: | 5'-D(*Cp*Gp*Tp*Cp*Gp*Tp*Gp*Gp*Ap*C)-3', 5'-D(*Gp*Tp*Cp*Cp*(A3A)p*Cp*Gp*Ap*Cp*G)-3' | | 著者 | Aramini, J.M, Cleaver, S.H, Pon, R.T, Cunningham, R.P, Germann, M.W. | | 登録日 | 2004-01-04 | | 公開日 | 2004-04-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of a DNA Duplex Containing an alpha-Anomeric Adenosine: Insights into Substrate Recognition by Endonuclease IV.
J.Mol.Biol., 338, 2004
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