3L82
| X-ray Crystal structure of TRF1 and Fbx4 complex | 分子名称: | F-box only protein 4, Telomeric repeat-binding factor 1 | 著者 | Zeng, Z.X, Wang, W, Yang, Y.T, Chen, Y, Yang, X.M, Diehl, J.A, Liu, X.D, Lei, M. | 登録日 | 2009-12-29 | 公開日 | 2010-03-09 | 最終更新日 | 2013-09-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural Basis of Selective Ubiquitination of TRF1 by SCF(Fbx4) Dev.Cell, 18, 2010
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4KFN
| Structure-Based Discovery of Novel Amide-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors | 分子名称: | 1,2-ETHANEDIOL, N-[4-(piperidin-1-ylsulfonyl)benzyl]-1H-pyrrolo[3,2-c]pyridine-2-carboxamide, Nicotinamide phosphoribosyltransferase, ... | 著者 | Zheng, X, Bauer, P, Baumeister, T, Buckmelter, A.J, Caligiuri, M, Clodfelter, K.H, Han, B, Ho, Y, Kley, N, Lin, J, Reynolds, D.J, Sharma, G, Smith, C.C, Wang, Z, Dragovich, P.S, Gunzner-Toste, J, Liederer, B.M, Ly, J, O'Brien, T, Oh, A, Wang, L, Wang, W, Xiao, Y, Zak, M, Zhao, G, Yuen, P, Bair, K.W. | 登録日 | 2013-04-27 | 公開日 | 2013-05-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (nampt) inhibitors. J.Med.Chem., 56, 2013
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5TUC
| Crystal Structure of the Sus TBC1D15 GAP Domain | 分子名称: | Sus TBC1D15 GAP Domain | 著者 | Chen, Y.-N, Wang, W, Cheng, D, Ge, Y, Gu, X, Zhou, X.E, Ye, F, Xu, H.E, Lv, Z. | 登録日 | 2016-11-05 | 公開日 | 2017-02-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of TBC1D15 GTPase-activating protein (GAP) domain and its activity on Rab GTPases. Protein Sci., 26, 2017
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7ESX
| Crystal structure of Wolbachia cytoplasmic incompatibility factor CidA from wPip | 分子名称: | Bacteria factor 1 | 著者 | Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T. | 登録日 | 2021-05-12 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors. Proc.Natl.Acad.Sci.USA, 118, 2021
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7ESY
| Crystal structure of the complex formed by Wolbachia cytoplasmic incompatibility factors CidA and CidBND1-ND2 from wPip | 分子名称: | Bacteria factor 1, CALCIUM ION, ULP_PROTEASE domain-containing protein | 著者 | Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T. | 登録日 | 2021-05-12 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.297 Å) | 主引用文献 | Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors. Proc.Natl.Acad.Sci.USA, 118, 2021
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7ESZ
| Crystal structure of the complex formed by Wolbachia cytoplasmic incompatibility factors CinA and CinB with Mn2+ from wPip | 分子名称: | BACTERIA FACTOR A, BACTERIA FACTOR B, MANGANESE (II) ION | 著者 | Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T. | 登録日 | 2021-05-12 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.476 Å) | 主引用文献 | Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors. Proc.Natl.Acad.Sci.USA, 118, 2021
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7ET0
| Crystal structure of the complex formed by Wolbachia cytoplasmic incompatibility factors CinA and CinB from wPip | 分子名称: | Bacteria factor A, Bacteria factor B | 著者 | Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T. | 登録日 | 2021-05-12 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors. Proc.Natl.Acad.Sci.USA, 118, 2021
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1AFF
| DNA QUADRUPLEX CONTAINING GGGG TETRADS AND (T.A).A TRIADS, NMR, 8 STRUCTURES | 分子名称: | QUADRUPLEX DNA (5'-D(TP*AP*GP*G)-3') | 著者 | Kettani, A, Bouaziz, S, Wang, W, Jones, R.A, Patel, D.J. | 登録日 | 1997-03-06 | 公開日 | 1997-08-20 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Bombyx mori single repeat telomeric DNA sequence forms a G-quadruplex capped by base triads. Nat.Struct.Biol., 4, 1997
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4JR5
| Structure-based Identification of Ureas as Novel Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors | 分子名称: | 1,2-ETHANEDIOL, 1-[4-(piperidin-1-ylsulfonyl)phenyl]-3-(pyridin-3-ylmethyl)thiourea, Nicotinamide phosphoribosyltransferase, ... | 著者 | Zheng, X, Bauer, P, Baumeister, T, Buckmelter, A.J, Caligiuri, M, Clodfelter, K.H, Han, B, Ho, Y, Kley, N, Lin, J, Reynolds, D.J, Sharma, G, Smith, C.C, Wang, Z, Dragovich, P.S, Oh, A, Wang, W, Zak, M, Gunzner-Toste, J, Zhao, G, Yuen, P, Bair, K.W. | 登録日 | 2013-03-21 | 公開日 | 2013-05-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.906 Å) | 主引用文献 | Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (nampt) inhibitors. J.Med.Chem., 56, 2013
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5TUB
| Crystal Structure of the Shark TBC1D15 GAP Domain | 分子名称: | Shark TBC1D15 GTPase-activating Protein | 著者 | Chen, Y.-N, Wang, W, Cheng, D, Ge, Y, Gu, X, Zhou, X.E, Ye, F, Xu, H.E, Lv, Z. | 登録日 | 2016-11-05 | 公開日 | 2017-02-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Crystal structure of TBC1D15 GTPase-activating protein (GAP) domain and its activity on Rab GTPases. Protein Sci., 26, 2017
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5URV
| Crystal structure of Frizzled 7 CRD in complex with C24 fatty acid | 分子名称: | (15E)-TETRACOS-15-ENOIC ACID, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Mukund, S, Nile, A.H, Stanger, K, Hannoush, R.N, Wang, W. | 登録日 | 2017-02-13 | 公開日 | 2017-05-10 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Unsaturated fatty acyl recognition by Frizzled receptors mediates dimerization upon Wnt ligand binding. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5URZ
| Crystal structure of Frizzled 5 CRD in complex with BOG | 分子名称: | Frizzled-5, alpha-L-fucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, octyl beta-D-glucopyranoside | 著者 | Mukund, S, Nile, A.H, Stanger, K, Hannoush, R.N, Wang, W. | 登録日 | 2017-02-13 | 公開日 | 2017-05-10 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | 主引用文献 | Unsaturated fatty acyl recognition by Frizzled receptors mediates dimerization upon Wnt ligand binding. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5GXT
| Crystal structure of PigG | 分子名称: | MAGNESIUM ION, Maltose-binding periplasmic protein,PigG | 著者 | Zhang, F, Ran, T, Xu, D, Wang, W. | 登録日 | 2016-09-20 | 公開日 | 2017-07-19 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.245 Å) | 主引用文献 | Crystal structure of MBP-PigG fusion protein and the essential function of PigG in the prodigiosin biosynthetic pathway in Serratia marcescens FS14. Int. J. Biol. Macromol., 99, 2017
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1D6D
| SOLUTION DNA STRUCTURE CONTAINING (A-A)-T TRIADS INTERDIGITATED BETWEEN A-T BASE PAIRS AND GGGG TETRADS; NMR, 8 STRUCT. | 分子名称: | 5'-D(*AP*AP*GP*GP*TP*TP*TP*TP*AP*AP*GP*G)-3' | 著者 | Kuryavyi, V.V, Kettani, A, Wang, W, Jones, R, Patel, D.J. | 登録日 | 1999-10-13 | 公開日 | 2000-01-17 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | A diamond-shaped zipper-like DNA architecture containing triads sandwiched between mismatches and tetrads. J.Mol.Biol., 295, 2000
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4JNM
| Discovery of Potent and Efficacious Urea-containing Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors with Reduced CYP2C9 Inhibition Properties | 分子名称: | 1,2-ETHANEDIOL, 1-[(6-aminopyridin-3-yl)methyl]-3-[4-(phenylsulfonyl)phenyl]urea, Nicotinamide phosphoribosyltransferase, ... | 著者 | Gunzner-Toste, J, Zhao, G, Bauer, P, Baumeister, T, Buckmelter, A.J, Caligiuri, M, Clodfelter, K.H, Fu, B, Han, B, Ho, Y, Kley, N, Liederer, B, Lin, J, Mukadam, S, O'Brien, T, Reynolds, D.J, Sharma, G, Skelton, N, Smith, C.C, Oh, A, Wang, W, Wang, Z, Xiao, Y, Yuen, P, Zak, M, Zhang, L, Zheng, X, Bair, K.W, Dragovich, P.S. | 登録日 | 2013-03-15 | 公開日 | 2013-05-29 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties. Bioorg.Med.Chem.Lett., 23, 2013
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5FGL
| Co-crystal Structure of NicR2_Hsp | 分子名称: | 4-oxidanylidene-4-(6-oxidanylidene-1~{H}-pyridin-3-yl)butanoic acid, NicR | 著者 | Zhang, K, Tang, H, Wu, G, Wang, W, Hu, H, Xu, P. | 登録日 | 2015-12-21 | 公開日 | 2016-12-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Co-crystal Structure of NicR2_Hsp To Be Published
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5GWD
| Structure of Myroilysin | 分子名称: | Myroilysin, ZINC ION | 著者 | Xu, D, Ran, T, Wang, W. | 登録日 | 2016-09-10 | 公開日 | 2017-02-15 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Myroilysin Is a New Bacterial Member of the M12A Family of Metzincin Metallopeptidases and Is Activated by a Cysteine Switch Mechanism. J. Biol. Chem., 292, 2017
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6J36
| crystal structure of Mycoplasma hyopneumoniae Enolase | 分子名称: | Enolase, GLYCEROL, SULFATE ION | 著者 | Chen, R, Zhang, S, Gan, R, Xie, X, Feng, Z, Wang, W, Ran, T, Zhang, W, Xiang, Q, Shao, G. | 登録日 | 2019-01-04 | 公開日 | 2019-05-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Featured Species-Specific Loops Are Found in the Crystal Structure ofMhpEno, a Cell Surface Adhesin FromMycoplasma hyopneumoniae. Front Cell Infect Microbiol, 9, 2019
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5GXV
| Crystal structure of PigG | 分子名称: | MAGNESIUM ION, Maltose-binding periplasmic protein,PigG | 著者 | Zhang, F, Ran, T, Xu, D, Wang, W. | 登録日 | 2016-09-20 | 公開日 | 2017-07-19 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of MBP-PigG fusion protein and the essential function of PigG in the prodigiosin biosynthetic pathway in Serratia marcescens FS14. Int. J. Biol. Macromol., 99, 2017
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1B3P
| 5'-D(*GP*GP*AP*GP*GP*AP*T)-3' | 分子名称: | DNA (5'-D(*GP*GP*AP*GP*GP*AP*T)-3') | 著者 | Kettani, A, Bouaziz, S, Skripkin, E, Majumdar, A, Wang, W, Jones, R.A, Patel, D.J. | 登録日 | 1998-12-14 | 公開日 | 1999-08-31 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Interlocked mismatch-aligned arrowhead DNA motifs. Structure Fold.Des., 7, 1999
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5T44
| Crystal structure of Frizzled 7 CRD | 分子名称: | Frizzled-7 | 著者 | Mukund, S, Nile, A.H, Stanger, K, Hannous, R.H, Wang, W. | 登録日 | 2016-08-29 | 公開日 | 2017-04-05 | 最終更新日 | 2017-05-03 | 実験手法 | X-RAY DIFFRACTION (1.9944 Å) | 主引用文献 | Unsaturated fatty acyl recognition by Frizzled receptors mediates dimerization upon Wnt ligand binding. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4KFP
| Identification of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-derived Ureas as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT) | 分子名称: | 1,2-ETHANEDIOL, N-(4-{[1-(tetrahydro-2H-pyran-4-yl)piperidin-4-yl]sulfonyl}benzyl)-2H-pyrrolo[3,4-c]pyridine-2-carboxamide, Nicotinamide phosphoribosyltransferase, ... | 著者 | Dragovich, P.S, Bair, K.W, Baumeister, T, Ho, Y, Liederer, B.M, Liu, X, O'Brien, T, Oeh, J, Sampath, D, Skelton, N, Wang, L, Wang, W, Wu, H, Xiao, Y, Yuen, P, Zak, M, Zhang, L, Zheng, X. | 登録日 | 2013-04-27 | 公開日 | 2013-08-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Identification of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-derived ureas as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). Bioorg.Med.Chem.Lett., 23, 2013
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7CLU
| PigF with SAH | 分子名称: | ACETATE ION, GLYCEROL, Methyltransferase domain-containing protein | 著者 | Qiu, S, Xu, D, Han, N, Sun, B, Ran, T, Wang, W. | 登録日 | 2020-07-22 | 公開日 | 2021-07-28 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of PigF, an O-methyltransferase involved in the prodigiosin synthetic pathway, reveal an induced-fit substrate-recognition mechanism. Iucrj, 9, 2022
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5H9U
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5FHP
| SeMet regulator of nicotine degradation | 分子名称: | GLYCEROL, MALONIC ACID, NicR | 著者 | Zhang, K, Tang, H, Wu, G, Wang, W, Hu, H, Xu, P. | 登録日 | 2015-12-22 | 公開日 | 2016-12-21 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Co-crystal Structure of NicR2_Hsp To Be Published
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