5URV
Crystal structure of Frizzled 7 CRD in complex with C24 fatty acid
Summary for 5URV
| Entry DOI | 10.2210/pdb5urv/pdb |
| Descriptor | Frizzled-7, (15E)-TETRACOS-15-ENOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
| Functional Keywords | frizzled 7, crd, immune system |
| Biological source | Homo sapiens (Human) |
| Cellular location | Cell membrane ; Multi-pass membrane protein : O75084 |
| Total number of polymer chains | 2 |
| Total formula weight | 35273.67 |
| Authors | Mukund, S.,Nile, A.H.,Stanger, K.,Hannoush, R.N.,Wang, W. (deposition date: 2017-02-13, release date: 2017-05-10, Last modification date: 2020-07-29) |
| Primary citation | Nile, A.H.,Mukund, S.,Stanger, K.,Wang, W.,Hannoush, R.N. Unsaturated fatty acyl recognition by Frizzled receptors mediates dimerization upon Wnt ligand binding. Proc. Natl. Acad. Sci. U.S.A., 114:4147-4152, 2017 Cited by PubMed: 28377511DOI: 10.1073/pnas.1618293114 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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