5URV

Crystal structure of Frizzled 7 CRD in complex with C24 fatty acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Frizzled-7	polymer	148	16469.6	2	UniProt (O75084) Pfam (PF01392)	Homo sapiens (Human)	hFz7,FzE3
2	C (A)	(15E)-TETRACOS-15-ENOIC ACID	non-polymer		366.6	1	Chemie (NER)
3	D, H (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
4	E, F, G, L, M... (A, B)	SULFATE ION	non-polymer		96.1	8	Chemie (SO4)
5	I, J, K (B)	2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL	non-polymer		252.3	3	Chemie (1PG)
6	Q, R (A, B)	water	water		18.0	239	Chemie (HOH)

Sequence modifications

A, B: 0 - 138 (UniProt: O75084)

PDB	External Database	Details
Ser 2	Ala 32	conflict
Gly 139	-	expression tag
Asn 140	-	expression tag
Ser 141	-	expression tag
His 142	-	expression tag
His 143	-	expression tag
His 144	-	expression tag
His 145	-	expression tag
His 146	-	expression tag
His 147	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	32939.2
Non-Polymers*	Number of molecules	14
	Total formula weight	2334.5
All*	Total formula weight	35273.7

*Water molecules are not included.