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4NGG
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BU of 4ngg by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 13-mer siRNA having 5'-A and UU-3' ends (2.6 Angstrom resolution)
分子名称: 5'-R(*AP*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3', Endoribonuclease Dicer, PHOSPHATE ION
著者Simanshu, D.K, Tian, Y, Patel, D.J.
登録日2013-11-01
公開日2014-03-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NGC
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BU of 4ngc by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 12-mer siRNA having UA-3' ends (2.1 Angstrom resolution)
分子名称: 5'-R(*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*A)-3', Endoribonuclease Dicer
著者Simanshu, D.K, Tian, Y, Patel, D.J.
登録日2013-11-01
公開日2014-03-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.104 Å)
主引用文献A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NH6
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BU of 4nh6 by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 15-mer siRNA having 5'-pUUU and UU-3' ends (2.55 Angstrom resolution)
分子名称: 5'-R(P*UP*UP*UP*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3', Endoribonuclease Dicer
著者Simanshu, D.K, Tian, Y, Patel, D.J.
登録日2013-11-04
公開日2014-03-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.551 Å)
主引用文献A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
3RIC
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BU of 3ric by Molmil
Crystal Structure of D48V||A47D mutant of Human Glycolipid Transfer Protein complexed with 3-O-sulfo-galactosylceramide containing nervonoyl acyl chain (24:1)
分子名称: (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, Glycolipid transfer protein
著者Samygina, V, Ochoa-Lizarralde, B, Patel, D.J, Brown, R.E, Malinina, L.
登録日2011-04-13
公開日2012-02-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein.
Structure, 19, 2011
3PT9
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BU of 3pt9 by Molmil
Crystal structure of mouse DNMT1(731-1602) in the free state
分子名称: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
著者Song, J, Patel, D.J.
登録日2010-12-02
公開日2010-12-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation.
Science, 331, 2011
3RIU
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BU of 3riu by Molmil
Crystal structure of Drosophila hexameric C3PO formed by truncated Translin and Trax
分子名称: Translin, Translin associated factor X, isoform B
著者Tian, Y, Simanshu, D.K, Patel, D.J.
登録日2011-04-14
公開日2011-05-11
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Multimeric assembly and biochemical characterization of the Trax-translin endonuclease complex.
Nat.Struct.Mol.Biol., 18, 2011
3OWW
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BU of 3oww by Molmil
Crystal structure of the glycine riboswitch bound to glycine
分子名称: GLYCINE, MAGNESIUM ION, domain II of glycine riboswitch
著者Huang, L, Serganov, A, Patel, D.J.
登録日2010-09-20
公開日2010-12-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.802 Å)
主引用文献Structural insights into ligand recognition by a sensing domain of the cooperative glycine riboswitch.
Mol.Cell, 40, 2010
3RB4
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BU of 3rb4 by Molmil
Dpo4 extension ternary complex with 3'-terminal primer G base opposite the 3-methylcytosine (m3c) lesion
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*C*CP*TP*AP*AP*CP*(ME6)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3'), ...
著者Rechkoblit, O, Patel, D.J.
登録日2011-03-28
公開日2011-06-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.805 Å)
主引用文献Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions.
Structure, 19, 2011
3RB0
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BU of 3rb0 by Molmil
Dpo4 extension ternary complex with 3'-terminal primer G base opposite the 1-methylguanine (M1G) lesion
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*C*CP*TP*AP*AP*CP*(MG1)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3'), ...
著者Rechkoblit, O, Patel, D.J.
登録日2011-03-28
公開日2011-06-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.225 Å)
主引用文献Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions.
Structure, 19, 2011
3O7X
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BU of 3o7x by Molmil
Crystal structure of human Hili PAZ domain
分子名称: Piwi-like protein 2
著者Tian, Y, Simanshu, D.K, Ma, J.-B, Patel, D.J.
登録日2010-08-01
公開日2011-01-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9248 Å)
主引用文献Inaugural Article: Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains.
Proc.Natl.Acad.Sci.USA, 108, 2011
3O33
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BU of 3o33 by Molmil
Crystal structure of TRIM24 PHD-Bromo in the free state
分子名称: Transcription intermediary factor 1-alpha, ZINC ION
著者Wang, Z, Patel, D.J.
登録日2010-07-23
公開日2010-12-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献TRIM24 links a non-canonical histone signature to breast cancer.
Nature, 468, 2010
3NNH
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BU of 3nnh by Molmil
Crystal Structure of the CUGBP1 RRM1 with GUUGUUUUGUUU RNA
分子名称: CUGBP Elav-like family member 1, RNA (5'-R(*GP*UP*UP*GP*UP*UP*UP*UP*GP*UP*UP*U)-3')
著者Teplova, M, Song, J, Gaw, H, Teplov, A, Patel, D.J.
登録日2010-06-23
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7501 Å)
主引用文献Structural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1.
Structure, 18, 2010
3QZT
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BU of 3qzt by Molmil
Crystal Structure of BPTF bromo in complex with histone H4K16ac - Form II
分子名称: GLYCEROL, Histone H4, Nucleosome-remodeling factor subunit BPTF
著者Li, H, Ruthenburg, A.J, Patel, D.J.
登録日2011-03-07
公開日2011-06-01
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions.
Cell(Cambridge,Mass.), 145, 2011
3RBE
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BU of 3rbe by Molmil
Dpo4 extension ternary complex with 3'-terminal primer t base opposite the 3-methylcytosine (m3c) lesion
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*C*CP*TP*AP*AP*CP*(ME6)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3'), ...
著者Rechkoblit, O, Patel, D.J.
登録日2011-03-29
公開日2011-06-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions.
Structure, 19, 2011
3RB6
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BU of 3rb6 by Molmil
Dpo4 extension ternary complex with 3'-terminal primer A base opposite the 3-methylcytosine (m3c) lesion
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ...
著者Rechkoblit, O, Patel, D.J.
登録日2011-03-28
公開日2011-06-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions.
Structure, 19, 2011
3PT6
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BU of 3pt6 by Molmil
Crystal structure of mouse DNMT1(650-1602) in complex with DNA
分子名称: DNA (5'-D(*CP*CP*TP*GP*CP*GP*GP*AP*GP*GP*CP*TP*CP*AP*CP*GP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*CP*GP*TP*GP*AP*GP*CP*CP*TP*CP*CP*GP*CP*AP*GP*G)-3'), DNA (cytosine-5)-methyltransferase 1, ...
著者Song, J, Patel, D.J.
登録日2010-12-02
公開日2010-12-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation.
Science, 331, 2011
3Q0D
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BU of 3q0d by Molmil
Crystal structure of SUVH5 SRA- hemi methylated CG DNA complex
分子名称: CHLORIDE ION, DNA (5'-D(*CP*TP*GP*AP*CP*GP*TP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*AP*(5CM)P*GP*TP*CP*AP*G)-3'), ...
著者Eerappa, R, Simanshu, D.K, Patel, D.J.
登録日2010-12-15
公開日2011-02-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3704 Å)
主引用文献A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo.
Genes Dev., 25, 2011
4ONQ
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BU of 4onq by Molmil
Crystal structure of ntDRM E283S/R309S/F310S/Y590S/D591S mutant
分子名称: DNA methyltransferase, SINEFUNGIN
著者Du, J, Patel, D.J.
登録日2014-01-28
公開日2014-06-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases.
Cell(Cambridge,Mass.), 157, 2014
3RAQ
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BU of 3raq by Molmil
Dpo4 extension ternary complex with 3'-terminal primer C base opposite the 1-methylguanine (MG1) lesion
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ...
著者Rechkoblit, O, Patel, D.J.
登録日2011-03-28
公開日2011-06-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions.
Structure, 19, 2011
4QEO
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BU of 4qeo by Molmil
crystal structure of KRYPTONITE in complex with mCHH DNA, H3(1-15) peptide and SAH
分子名称: DNA 5'-ACTGATGAGTACCAT-3', DNA 5'-GGTACT(5CM)ATCAGTAT-3', Histone H3, ...
著者Du, J, Li, S, Patel, D.J.
登録日2014-05-17
公開日2014-07-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE.
Mol.Cell, 55, 2014
3RAX
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BU of 3rax by Molmil
Dpo4 extension ternary complex with 3'-terminal primer T base opposite the 1-methylguanine (M1G) lesion
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*CP*TP*AP*AP*CP*(MG1)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3'), ...
著者Rechkoblit, O, Patel, D.J.
登録日2011-03-28
公開日2011-06-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.891 Å)
主引用文献Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions.
Structure, 19, 2011
4QLN
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BU of 4qln by Molmil
structure of ydao riboswitch binding with c-di-dAMP
分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, RNA (117-MER)
著者Ren, A.M, Patel, D.J.
登録日2014-06-12
公開日2014-08-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献c-di-AMP binds the ydaO riboswitch in two pseudo-symmetry-related pockets.
Nat.Chem.Biol., 10, 2014
3RV1
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BU of 3rv1 by Molmil
Crystal structure of the N-terminal and RNase III domains of K. polysporus Dcr1 E224Q mutant
分子名称: K. polysporus Dcr1
著者Nakanishi, K, Weinberg, D.E, Bartel, D.P, Patel, D.J.
登録日2011-05-05
公開日2011-08-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.975 Å)
主引用文献The inside-out mechanism of dicers from budding yeasts.
Cell(Cambridge,Mass.), 146, 2011
3RW6
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BU of 3rw6 by Molmil
Structure of nuclear RNA export factor TAP bound to CTE RNA
分子名称: Nuclear RNA export factor 1, constitutive transport element(CTE)of Mason-Pfizer monkey virus RNA
著者Teplova, M, Khin, N.W, Patel, D.J, Izaurralde, E.
登録日2011-05-07
公開日2011-08-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP.
Nat.Struct.Mol.Biol., 18, 2011
4QXC
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BU of 4qxc by Molmil
Crystal structure of histone demethylase KDM2A-H3K36ME2 with NOG
分子名称: Histone H3.2, Lysine-specific demethylase 2A, N-OXALYLGLYCINE, ...
著者Cheng, Z.J, Patel, D.J.
登録日2014-07-19
公開日2014-11-05
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014

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