5B6G
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![BU of 5b6g by Molmil](/molmil-images/mine/5b6g) | Protein-protein interaction | 分子名称: | Adenomatous polyposis coli protein, GLYCEROL, PHQ-ALA-GLY-GLU-ALA-XYC-TYR-GLU, ... | 著者 | Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J. | 登録日 | 2016-05-27 | 公開日 | 2017-05-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration. Nat. Chem. Biol., 13, 2017
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4XQW
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![BU of 4xqw by Molmil](/molmil-images/mine/4xqw) | X-ray structure analysis of xylanase-N44E with MES at pH6.0 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Endo-1,4-beta-xylanase 2, IODIDE ION | 著者 | Wan, Q, Park, J.M, Riccardi, D.M, Hanson, L.B, Fisher, Z, Smith, J.C, Ostermann, A, Schrader, T, Graham, D.E, Coates, L, Langan, P, Kovalevsky, A.Y. | 登録日 | 2015-01-20 | 公開日 | 2015-09-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Direct determination of protonation states and visualization of hydrogen bonding in a glycoside hydrolase with neutron crystallography. Proc.Natl.Acad.Sci.USA, 112, 2015
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4XPV
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![BU of 4xpv by Molmil](/molmil-images/mine/4xpv) | Neutron and X-ray structure analysis of xylanase: N44D at pH6 | 分子名称: | Endo-1,4-beta-xylanase 2, IODIDE ION | 著者 | Wan, Q, Park, J.M, Riccardi, D.M, Hanson, L.B, Fisher, Z, Smith, J.C, Ostermann, A, Schrader, T, Graham, D.E, Coates, L, Langan, P, Kovalevsky, A.Y. | 登録日 | 2015-01-18 | 公開日 | 2015-09-30 | 最終更新日 | 2023-09-27 | 実験手法 | NEUTRON DIFFRACTION (1.7 Å), X-RAY DIFFRACTION | 主引用文献 | Direct determination of protonation states and visualization of hydrogen bonding in a glycoside hydrolase with neutron crystallography. Proc.Natl.Acad.Sci.USA, 112, 2015
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4XQ4
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![BU of 4xq4 by Molmil](/molmil-images/mine/4xq4) | X-ray structure analysis of xylanase - N44D | 分子名称: | Endo-1,4-beta-xylanase 2, IODIDE ION | 著者 | Wan, Q, Park, J.M, Riccardi, D.M, Hanson, L.B, Fisher, Z, Smith, J.C, Ostermann, A, Schrader, T, Graham, D.E, Coates, L, Langan, P, Kovalevsky, A.Y. | 登録日 | 2015-01-19 | 公開日 | 2015-09-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Direct determination of protonation states and visualization of hydrogen bonding in a glycoside hydrolase with neutron crystallography. Proc.Natl.Acad.Sci.USA, 112, 2015
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4XQD
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![BU of 4xqd by Molmil](/molmil-images/mine/4xqd) | X-ray structure analysis of xylanase-WT at pH4.0 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endo-1,4-beta-xylanase 2, IODIDE ION | 著者 | Wan, Q, Park, J.M, Riccardi, D.M, Hanson, L.B, Fisher, Z, Smith, J.C, Ostermann, A, Schrader, T, Graham, D.E, Coates, L, Langan, P, Kovalevsky, A.Y. | 登録日 | 2015-01-19 | 公開日 | 2015-09-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Direct determination of protonation states and visualization of hydrogen bonding in a glycoside hydrolase with neutron crystallography. Proc.Natl.Acad.Sci.USA, 112, 2015
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4XXB
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![BU of 4xxb by Molmil](/molmil-images/mine/4xxb) | Crystal structure of human MDM2-RPL11 | 分子名称: | 60S ribosomal protein L11, BETA-MERCAPTOETHANOL, E3 ubiquitin-protein ligase Mdm2, ... | 著者 | Zheng, J, Chen, Z. | 登録日 | 2015-01-30 | 公開日 | 2015-08-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of human MDM2 complexed with RPL11 reveals the molecular basis of p53 activation Genes Dev., 29, 2015
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4NNI
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![BU of 4nni by Molmil](/molmil-images/mine/4nni) | Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide | 分子名称: | 30S ribosomal protein S1, PYRAZINE-2-CARBOXYLIC ACID | 著者 | Yang, J, Liu, Y, Cai, Q, Lin, D. | 登録日 | 2013-11-18 | 公開日 | 2014-12-24 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide. Mol.Microbiol., 95, 2015
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4Y4R
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![BU of 4y4r by Molmil](/molmil-images/mine/4y4r) | Crystal structure of ribosomal oxygenase NO66 dimer mutant | 分子名称: | ACETATE ION, Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66, NICKEL (II) ION | 著者 | Wang, C, Hang, T, Zang, J. | 登録日 | 2015-02-11 | 公開日 | 2015-10-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structure of the JmjC domain-containing protein NO66 complexed with ribosomal protein Rpl8. Acta Crystallogr.,Sect.D, 71, 2015
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4NNG
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3MGM
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![BU of 3mgm by Molmil](/molmil-images/mine/3mgm) | Crystal structure of human NUDT16 | 分子名称: | U8 snoRNA-decapping enzyme | 著者 | Yan, J, Lu, G, Zhang, J, Qi, J, Li, Z, Gao, F. | 登録日 | 2010-04-07 | 公開日 | 2011-04-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Crystal structure and the template mRNA decapping activity of human NUDT16 To be Published
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4NNK
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4ZHU
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![BU of 4zhu by Molmil](/molmil-images/mine/4zhu) | Crystal structure of a bacterial repressor protein | 分子名称: | SULFATE ION, YfiR | 著者 | Li, S, Li, T, Wang, Y, Bartlam, M. | 登録日 | 2015-04-27 | 公開日 | 2016-04-27 | 実験手法 | X-RAY DIFFRACTION (2.3968 Å) | 主引用文献 | Structural insights into YfiR sequestering by YfiB in Pseudomonas aeruginosa PAO1 Sci Rep, 5, 2015
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4ZHW
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4ZHY
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![BU of 4zhy by Molmil](/molmil-images/mine/4zhy) | Crystal structure of a bacterial signalling complex | 分子名称: | FORMIC ACID, SULFATE ION, YfiB, ... | 著者 | Li, S, Li, T, Wang, Y, Bartlam, M. | 登録日 | 2015-04-27 | 公開日 | 2016-04-27 | 実験手法 | X-RAY DIFFRACTION (1.969 Å) | 主引用文献 | Structural insights into YfiR sequestering by YfiB in Pseudomonas aeruginosa PAO1 Sci Rep, 5, 2015
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4ZHV
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![BU of 4zhv by Molmil](/molmil-images/mine/4zhv) | Crystal structure of a bacterial signalling protein | 分子名称: | SULFATE ION, YfiB | 著者 | Li, S, Li, T, Wang, Y, Bartlam, M. | 登録日 | 2015-04-27 | 公開日 | 2016-04-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.585 Å) | 主引用文献 | Structural insights into YfiR sequestering by YfiB in Pseudomonas aeruginosa PAO1 Sci Rep, 5, 2015
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4NNH
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6LHE
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![BU of 6lhe by Molmil](/molmil-images/mine/6lhe) | Crystal Structure of Gold-bound NDM-1 | 分子名称: | GOLD ION, Metallo-beta-lactamase type 2, SULFATE ION | 著者 | Wang, H, Sun, H, Wang, M. | 登録日 | 2019-12-07 | 公開日 | 2020-09-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.206 Å) | 主引用文献 | Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin. Nat Commun, 11, 2020
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6PBC
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![BU of 6pbc by Molmil](/molmil-images/mine/6pbc) | Structural basis for the activation of PLC-gamma isozymes by phosphorylation and cancer-associated mutations | 分子名称: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma,1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, CALCIUM ION, SODIUM ION | 著者 | Hajicek, N, Sondek, J. | 登録日 | 2019-06-13 | 公開日 | 2020-01-08 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Structural basis for the activation of PLC-gamma isozymes by phosphorylation and cancer-associated mutations. Elife, 8, 2019
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3Q96
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![BU of 3q96 by Molmil](/molmil-images/mine/3q96) | B-Raf kinase domain in complex with a tetrahydronaphthalene inhibitor | 分子名称: | (2S)-N-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-7-[(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-4-yl)oxy]-1,2,3,4-tetrahydronaphthalene-2-carboxamide, Serine/threonine-protein kinase B-raf | 著者 | Sintchak, M.D, Aertgeerts, K, Yano, J. | 登録日 | 2011-01-07 | 公開日 | 2011-03-23 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Design and optimization of potent and orally bioavailable tetrahydronaphthalene raf inhibitors. J.Med.Chem., 54, 2011
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1WWN
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![BU of 1wwn by Molmil](/molmil-images/mine/1wwn) | NMR Solution Structure of BmK-betaIT, an Excitatory Scorpion Toxin from Buthus martensi Karsch | 分子名称: | Excitatory insect selective toxin 1 | 著者 | Wu, H, Tong, X, Chen, X, Zhang, Q, Zheng, X, Zhang, N, Wu, G. | 登録日 | 2005-01-10 | 公開日 | 2006-01-17 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution structure of BmK-betaIT, an excitatory scorpion beta-toxin without a 'hot spot' at the relevant position Biochem.Biophys.Res.Commun., 349, 2006
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4RQF
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![BU of 4rqf by Molmil](/molmil-images/mine/4rqf) | human Seryl-tRNA synthetase dimer complexed with one molecule of tRNAsec | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SERINE, Serine--tRNA ligase, ... | 著者 | Xie, W, Wang, C, Guo, Y, Tian, Q, Jia, Q. | 登録日 | 2014-11-03 | 公開日 | 2015-11-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.503 Å) | 主引用文献 | SerRS-tRNASec complex structures reveal mechanism of the first step in selenocysteine biosynthesis. Nucleic Acids Res., 43, 2015
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4RQE
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![BU of 4rqe by Molmil](/molmil-images/mine/4rqe) | human Seryl-tRNA synthetase dimer complexed with two molecules of tRNAsec | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SERINE, Serine--tRNA ligase, ... | 著者 | Xie, W, Wang, C, Guo, Y, Tian, Q, Jia, Q. | 登録日 | 2014-11-03 | 公開日 | 2015-11-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | SerRS-tRNASec complex structures reveal mechanism of the first step in selenocysteine biosynthesis. Nucleic Acids Res., 43, 2015
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1M3G
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4R91
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![BU of 4r91 by Molmil](/molmil-images/mine/4r91) | BACE-1 in complex with (R)-4-(2-cyclohexylethyl)-4-(((1S,3R)-3-(cyclopentylamino)cyclohexyl)methyl)-1-methyl-5-oxoimidazolidin-2-iminium | 分子名称: | (2E,5R)-5-(2-cyclohexylethyl)-5-{[(1S,3R)-3-(cyclopentylamino)cyclohexyl]methyl}-2-imino-3-methylimidazolidin-4-one, Beta-secretase 1, L(+)-TARTARIC ACID | 著者 | Orth, P, Caldwell, J.P, Strickland, C. | 登録日 | 2014-09-03 | 公開日 | 2014-11-05 | 最終更新日 | 2014-12-17 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Discovery of potent iminoheterocycle BACE1 inhibitors. Bioorg.Med.Chem.Lett., 24, 2014
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4R95
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![BU of 4r95 by Molmil](/molmil-images/mine/4r95) | BACE-1 in complex with 2-(((1R,3S)-3-(((R)-4-(2-cyclohexylethyl)-2-iminio-1-methyl-5-oxoimidazolidin-4-yl)methyl)cyclohexyl)amino)quinolin-1-ium | 分子名称: | (2E,5R)-5-(2-cyclohexylethyl)-2-imino-3-methyl-5-{[(1S,3R)-3-(quinolin-2-ylamino)cyclohexyl]methyl}imidazolidin-4-one, Beta-secretase 1, L(+)-TARTARIC ACID | 著者 | Orth, P, Strickland, C, Caldwell, J.P. | 登録日 | 2014-09-03 | 公開日 | 2014-11-05 | 最終更新日 | 2014-12-17 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Discovery of potent iminoheterocycle BACE1 inhibitors. Bioorg.Med.Chem.Lett., 24, 2014
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