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4YTK
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BU of 4ytk by Molmil
Structure of the KOW1-Linker1 domain of Transcription Elongation Factor Spt5
分子名称: Transcription elongation factor SPT5
著者Meyer, P.A, Li, S, Zhang, M, Yamada, K, Takagi, Y, Hartzog, G.A, Fu, J.
登録日2015-03-17
公開日2015-08-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.0904 Å)
主引用文献Structures and Functions of the Multiple KOW Domains of Transcription Elongation Factor Spt5.
Mol.Cell.Biol., 35, 2015
4RGJ
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BU of 4rgj by Molmil
Apo crystal structure of CDPK4 from Plasmodium falciparum, PF3D7_0717500
分子名称: Calcium-dependent protein kinase 4
著者Wernimont, A.K, Walker, J.R, Hutchinson, A, Seitova, A, He, H, Loppnau, P, Neculai, M, Amani, M, Lin, Y.H, Ravichandran, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Lovato, D.V, Structural Genomics Consortium (SGC)
登録日2014-09-30
公開日2014-10-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Apo crystal structure of CDPK4 from Plasmodium falciparum, PF3D7_0717500
To be Published
5M3M
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BU of 5m3m by Molmil
Free monomeric RNA polymerase I at 4.0A resolution
分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
著者Neyer, S, Kunz, M, Geiss, C, Hantsche, M, Hodirnau, V.-V, Seybert, A, Engel, C, Scheffer, M.P, Cramer, P, Frangakis, A.S.
登録日2016-10-15
公開日2016-11-23
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure of RNA polymerase I transcribing ribosomal DNA genes.
Nature, 540, 2016
4YL8
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BU of 4yl8 by Molmil
Crystal structure of the Crumbs/Moesin complex
分子名称: GLYCEROL, IODIDE ION, Moesin, ...
著者Wei, Z, Li, Y, Zhang, M.
登録日2015-03-05
公開日2015-04-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Basis for the Phosphorylation-regulated Interaction between the Cytoplasmic Tail of Cell Polarity Protein Crumbs and the Actin-binding Protein Moesin
J.Biol.Chem., 290, 2015
5WBX
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BU of 5wbx by Molmil
Structural insights into the potency of SK/IK channel positive modulators
分子名称: (3Z)-6-bromo-3-(hydroxyimino)-5-methyl-1,3-dihydro-2H-indol-2-one, CALCIUM ION, Calmodulin-1, ...
著者Nam, Y.W, Zhang, M.
登録日2017-06-29
公開日2017-12-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into the potency of SK channel positive modulators.
Sci Rep, 7, 2017
5WC5
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BU of 5wc5 by Molmil
Structural insights into the potency of SK/IK channel positive modulators
分子名称: 7-fluoro-3-(hydroxyamino)-2H-indol-2-one, CALCIUM ION, Calmodulin-1, ...
著者Nam, Y.W, Zhang, M.
登録日2017-06-29
公開日2017-12-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural insights into the potency of SK channel positive modulators.
Sci Rep, 7, 2017
1M5Z
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BU of 1m5z by Molmil
The PDZ7 of Glutamate Receptor Interacting Protein Binds to its Target via a Novel Hydrophobic Surface Area
分子名称: AMPA receptor interacting protein
著者Feng, W, Fan, J, Jiang, M, Shi, Y, Zhang, M.
登録日2002-07-11
公開日2002-11-06
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The PDZ7 of Glutamate Receptor Interacting Protein Binds to its Target via a Novel Hydrophobic Surface Area
J.Biol.Chem., 277, 2002
5ET0
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BU of 5et0 by Molmil
Crystal structure of Myo3b-ARB2 in complex with Espin1-AR
分子名称: Espin, Myosin-IIIb
著者Liu, H, Li, J, Liu, W, Zhang, M.
登録日2015-11-17
公開日2016-02-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin
Elife, 5, 2016
5ET1
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Crystal structure of Myo3b-ARB1 in complex with Espin1-AR
分子名称: Espin, GLYCEROL, Myosin-IIIb
著者Liu, H, Li, J, liu, W, Zhang, M.
登録日2015-11-17
公開日2016-02-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin
Elife, 5, 2016
1IU0
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BU of 1iu0 by Molmil
The first PDZ domain of PSD-95
分子名称: PSD-95
著者Long, J.-F, Tochio, H, Wang, P, Sala, C, Niethammer, M, Sheng, M, Zhang, M.
登録日2002-02-18
公開日2003-03-11
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Supramodular structure and synergistic target binding of the N-terminal tandem PDZ domains of PSD-95
J.MOL.BIOL., 327, 2003
4YTL
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BU of 4ytl by Molmil
Structure of the KOW2-KOW3 Domain of Transcription Elongation Factor Spt5.
分子名称: GLYCEROL, SULFATE ION, Transcription elongation factor SPT5
著者Meyer, P.A, Li, S, ZHang, M, Yamada, K, Takagi, Y, Hartzog, G.A, Fu, J.
登録日2015-03-17
公開日2015-08-12
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Structures and Functions of the Multiple KOW Domains of Transcription Elongation Factor Spt5.
Mol.Cell.Biol., 35, 2015
5F3X
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BU of 5f3x by Molmil
Crystal structure of Harmonin NPDZ1 in complex with ANKS4B SAM-PBM
分子名称: Ankyrin repeat and SAM domain-containing protein 4B, CHLORIDE ION, Harmonin
著者Li, J, He, Y, Lu, Q, Zhang, M.
登録日2015-12-03
公開日2016-03-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.649 Å)
主引用文献Mechanistic Basis of Organization of the Harmonin/USH1C-Mediated Brush Border Microvilli Tip-Link Complex
Dev.Cell, 36, 2016
5F3Y
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BU of 5f3y by Molmil
Crystal Structure of Myo7b N-MyTH4-FERM-SH3 in complex with Anks4b CEN
分子名称: Ankyrin repeat and SAM domain-containing protein 4B, Unconventional myosin-VIIb
著者Li, J, He, Y, Lu, Q, Zhang, M.
登録日2015-12-03
公開日2016-03-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.409 Å)
主引用文献Mechanistic Basis of Organization of the Harmonin/USH1C-Mediated Brush Border Microvilli Tip-Link Complex
Dev.Cell, 36, 2016
1IU2
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BU of 1iu2 by Molmil
The first PDZ domain of PSD-95
分子名称: PSD-95
著者Long, J.-F, Tochio, H, Wang, P, Sala, C, Niethammer, M, Sheng, M, Zhang, M.
登録日2002-02-19
公開日2003-03-11
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Supramodular structure and synergistic target binding of the N-terminal tandem PDZ domains of PSD-95
J.MOL.BIOL., 327, 2003
3WP1
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BU of 3wp1 by Molmil
Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl
分子名称: Disks large homolog 4, Lethal(2) giant larvae protein homolog 2, SULFATE ION
著者Zhu, J, Shang, Y, Wan, Q, Xia, Y, Chen, J, Du, Q, Zhang, M.
登録日2014-01-08
公開日2014-03-19
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.804 Å)
主引用文献Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl
Cell Res., 24, 2014
3WP0
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BU of 3wp0 by Molmil
Crystal structure of Dlg GK in complex with a phosphor-Lgl2 peptide
分子名称: Disks large homolog 4, GLYCEROL, Lethal(2) giant larvae protein homolog 2
著者Zhu, J, Shang, Y, Wan, Q, Xia, Y, Chen, J, Du, Q, Zhang, M.
登録日2014-01-08
公開日2014-03-19
最終更新日2014-04-30
実験手法X-RAY DIFFRACTION (2.039 Å)
主引用文献Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl
Cell Res., 24, 2014
3OMX
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BU of 3omx by Molmil
Crystal structure of Ssu72 with vanadate complex
分子名称: CG14216, VANADATE ION
著者Zhang, Y, Zhang, M, Zhang, Y.
登録日2010-08-27
公開日2011-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3366 Å)
主引用文献Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue.
Biochem.J., 434, 2011
5KH3
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BU of 5kh3 by Molmil
Crystal structure of fragment (3-(5-Chloro-1,3-benzothiazol-2-yl)propanoic acid) bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain
分子名称: 3-(5-chloranyl-1,3-benzothiazol-2-yl)propanoic acid, Histone deacetylase 6, UNKNOWN ATOM OR ION, ...
著者Harding, R.J, Dong, A, Ravichandran, M, Ferreira de Freitas, R, Schapira, M, Bountra, C, Edwards, A.M, Santhakumar, V, Arrowsmith, C.M, Structural Genomics Consortium (SGC)
登録日2016-06-14
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Small Molecule Antagonists of the Interaction between the Histone Deacetylase 6 Zinc-Finger Domain and Ubiquitin.
J. Med. Chem., 60, 2017
3OMW
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BU of 3omw by Molmil
Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II
分子名称: CG14216
著者Zhang, Y, Zhang, M, Zhang, Y.
登録日2010-08-27
公開日2011-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8701 Å)
主引用文献Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue.
Biochem.J., 434, 2011
5KH9
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BU of 5kh9 by Molmil
Crystal structure of a low occupancy fragment candidate (5-[(4-Isopropylphenyl)amino]-6-methyl-1,2,4-triazin-3(2H)-one) bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain
分子名称: 6-methyl-5-[(4-propan-2-ylphenyl)amino]-2~{H}-1,2,4-triazin-3-one, FORMIC ACID, Histone deacetylase 6, ...
著者Harding, R.J, Tempel, W, Ravichandran, M, Collins, P, Pearce, N, Brandao-Neto, J, Douangamath, A, Schapira, M, Bountra, C, Edwards, A.M, von Delft, F, Santhakumar, V, Arrowsmith, C.M, Structural Genomics Consortium (SGC)
登録日2016-06-14
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Small Molecule Antagonists of the Interaction between the Histone Deacetylase 6 Zinc-Finger Domain and Ubiquitin.
J. Med. Chem., 60, 2017
5KH7
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BU of 5kh7 by Molmil
Crystal structure of fragment (3-[6-Oxo-3-(3-pyridinyl)-1(6H)-pyridazinyl]propanoic acid) bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain
分子名称: 3-(6-oxidanylidene-3-pyridin-3-yl-pyridazin-1-yl)propanoic acid, Histone deacetylase 6, UNKNOWN ATOM OR ION, ...
著者Harding, R.J, Walker, J, Ravichandran, M, Ferreira de Freitas, R, Schapira, M, Bountra, C, Edwards, A.M, Santhakumar, V, Arrowsmith, C.M, Structural Genomics Consortium (SGC)
登録日2016-06-14
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Small Molecule Antagonists of the Interaction between the Histone Deacetylase 6 Zinc-Finger Domain and Ubiquitin.
J. Med. Chem., 60, 2017
6CU8
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BU of 6cu8 by Molmil
Alpha Synuclein fibril formed by full length protein - Twister Polymorph
分子名称: Alpha-synuclein
著者Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L.
登録日2018-03-23
公開日2018-09-12
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018
2QT5
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BU of 2qt5 by Molmil
Crystal Structure of GRIP1 PDZ12 in Complex with the Fras1 Peptide
分子名称: (ASN)(ASN)(LEU)(GLN)(ASP)(GLY)(THR)(GLU)(VAL), 1,2-ETHANEDIOL, ACETIC ACID, ...
著者Long, J, Wei, Z, Feng, W, Zhao, Y, Zhang, M.
登録日2007-08-01
公開日2008-06-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Supramodular nature of GRIP1 revealed by the structure of its PDZ12 tandem in complex with the carboxyl tail of Fras1.
J.Mol.Biol., 375, 2008
7U6F
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BU of 7u6f by Molmil
Mouse retromer (VPS26/VPS35/VPS29) heterotrimers
分子名称: 1,2-ETHANEDIOL, GLYCEROL, SULFATE ION, ...
著者Kendall, A.K, Chandra, M, Jackson, L.P.
登録日2022-03-04
公開日2022-10-12
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Improved mammalian retromer cryo-EM structures reveal a new assembly interface.
J.Biol.Chem., 298, 2022
4ZCG
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BU of 4zcg by Molmil
Crystal Structure of human GGT1 in complex with Glutamate (with all atoms of glutamate)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLUTAMIC ACID, ...
著者Terzyan, S, Hanigan, M.
登録日2015-04-15
公開日2015-06-03
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Human gamma-Glutamyl Transpeptidase 1: STRUCTURES OF THE FREE ENZYME, INHIBITOR-BOUND TETRAHEDRAL TRANSITION STATES, AND GLUTAMATE-BOUND ENZYME REVEAL NOVEL MOVEMENT WITHIN THE ACTIVE SITE DURING CATALYSIS.
J.Biol.Chem., 290, 2015

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件を2024-11-06に公開中

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