8UVT
 
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7NUY
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7NUZ
 | | Proteinase K structure at atomic resolution from crystals grown in agarose gel | | 分子名称: | GLYCEROL, MAGNESIUM ION, NITRATE ION, ... | | 著者 | Gavira, J.A, Artusio, F, Castellvi, A, Pisano, R. | | 登録日 | 2021-03-15 | | 公開日 | 2022-01-19 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | | 主引用文献 | Tuning Transport Phenomena in Agarose Gels for the Control of Protein Nucleation Density and Crystal Form
Crystals, 2021
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7O4B
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7NZZ
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7NWU
 | | Co-crystal structure of UPF3B-RRM-NOPS-L with UPF2-MIF4GIII | | 分子名称: | PENTAETHYLENE GLYCOL, Regulator of nonsense transcripts 2, Regulator of nonsense transcripts 3B, ... | | 著者 | Powers, K.T, Bufton, J.C, Szeto, J.A, Schaffitzel, C. | | 登録日 | 2021-03-17 | | 公開日 | 2022-07-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structures of nonsense-mediated mRNA decay factors UPF3B and UPF3A in complex with UPF2 reveal molecular basis for competitive binding and for neurodevelopmental disorder-causing mutation.
Nucleic Acids Res., 50, 2022
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7NTM
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7OIO
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7OK9
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7OOL
 | | Crystal structure of a Candidatus photodesmus katoptron thioredoxin chimera containing an ancestral loop | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Gavira, J.A, Ibarra-Molero, B, Gamiz-Arco, G, Risso, V, Sanchez-Ruiz, J.M. | | 登録日 | 2021-05-28 | | 公開日 | 2021-11-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Combining Ancestral Reconstruction with Folding-Landscape Simulations to Engineer Heterologous Protein Expression.
J.Mol.Biol., 433, 2021
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7P3C
 | | EED in complex with compound 4 | | 分子名称: | N-(2,3-dihydro-1-benzofuran-4-ylmethyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, N-[5-[(5-fluoranyl-2,3-dihydro-1-benzofuran-4-yl)methylamino]-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl]benzamide, Polycomb protein EED | | 著者 | Read, J.A. | | 登録日 | 2021-07-07 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Diverse, Potent, and Efficacious Inhibitors That Target the EED Subunit of the Polycomb Repressive Complex 2 Methyltransferase.
J.Med.Chem., 64, 2021
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7P3J
 | | EED in complex with compound 4 | | 分子名称: | 8-[6-[(dimethylamino)methyl]-2-methyl-pyridin-3-yl]-5-[(5-fluoranyl-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2H-pyrido[3,4-d]pyridazin-1-one, MAGNESIUM ION, N-(2,3-dihydro-1-benzofuran-4-ylmethyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, ... | | 著者 | Read, J.A. | | 登録日 | 2021-07-07 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Diverse, Potent, and Efficacious Inhibitors That Target the EED Subunit of the Polycomb Repressive Complex 2 Methyltransferase.
J.Med.Chem., 64, 2021
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7P3G
 | | EED in complex with compound 4 | | 分子名称: | N-(2,3-dihydro-1-benzofuran-4-ylmethyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, N5-[(5-fluoranyl-2,3-dihydro-1-benzofuran-4-yl)methyl]-N8-methyl-N8-(1-methylpyrazol-3-yl)-[1,2,4]triazolo[4,3-c]pyrimidine-5,8-diamine, Polycomb protein EED | | 著者 | Read, J.A. | | 登録日 | 2021-07-07 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Diverse, Potent, and Efficacious Inhibitors That Target the EED Subunit of the Polycomb Repressive Complex 2 Methyltransferase.
J.Med.Chem., 64, 2021
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7PAG
 | | The pore conformation of lymphocyte perforin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Perforin-1 | | 著者 | Ivanova, M.E, Lukoyanova, N, Malhotra, S, Topf, M, Trapani, J.A, Voskoboinik, I, Saibil, H.R. | | 登録日 | 2021-07-29 | | 公開日 | 2022-02-16 | | 最終更新日 | 2022-02-23 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | The pore conformation of lymphocyte perforin.
Sci Adv, 8, 2022
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7P92
 | | TmHydABC- T. maritima bifurcating hydrogenase with bridge domain up | | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, Fe-hydrogenase, ... | | 著者 | Furlan, C, Chongdar, N, Gupta, P, Lubitz, W, Ogata, H, Blaza, J.N, Birrell, J.A. | | 登録日 | 2021-07-23 | | 公開日 | 2022-09-14 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural insight on the mechanism of an electron-bifurcating [FeFe] hydrogenase.
Elife, 11, 2022
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7P8N
 | | TmHydABC- T. maritima hydrogenase with bridge closed | | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, Fe-hydrogenase, ... | | 著者 | Furlan, C, Chongdar, N, Gupta, P, Lubitz, W, Ogata, H, Blaza, J.N, Birrell, J.A. | | 登録日 | 2021-07-23 | | 公開日 | 2022-09-14 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural insight on the mechanism of an electron-bifurcating [FeFe] hydrogenase.
Elife, 11, 2022
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7P91
 | | TmHydABC- T. maritima bifurcating hydrogenase with bridge domain closed | | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, Fe-hydrogenase, ... | | 著者 | Furlan, C, Chongdar, N, Gupta, P, Lubitz, W, Ogata, H, Blaza, J.N, Birrell, J.A. | | 登録日 | 2021-07-23 | | 公開日 | 2022-09-14 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural insight on the mechanism of an electron-bifurcating [FeFe] hydrogenase.
Elife, 11, 2022
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7P5H
 | | TmHydABC- D2 map | | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, Fe-hydrogenase, ... | | 著者 | Furlan, C, Chongdar, N, Gupta, P, Lubitz, W, Ogata, H, Blaza, J.N, Birrell, J.A. | | 登録日 | 2021-07-14 | | 公開日 | 2022-09-14 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Structural insight on the mechanism of an electron-bifurcating [FeFe] hydrogenase.
Elife, 11, 2022
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7OXW
 | | CrabP2 mutant R30DK31D | | 分子名称: | ACETATE ION, Cellular retinoic acid-binding protein 2, SULFATE ION | | 著者 | Pastok, M.W, Basle, A, Endicott, J.A. | | 登録日 | 2021-06-23 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | | 主引用文献 | Structural requirements for the specific binding of CRABP2 to cyclin D3
To Be Published
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7OZH
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7OZT
 | | Nanobodies restore stability to cancer-associated mutants of tumor suppressor protein p16INK4a | | 分子名称: | Camelid nanobody NB09, Cyclin-dependent kinase inhibitor 2A | | 著者 | Pastok, M.W, Burbidge, O, Itzhaki, L, Endicott, J.A, Noble, M.E.M. | | 登録日 | 2021-06-28 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Nanobodies restore stability to cancer-associated mutants of tumor suppressor protein p16INK4a
To Be Published
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7OZG
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7P4A
 | | Non-canonical Staphylococcus aureus pathogenicity island repression. | | 分子名称: | Sri, Stl | | 著者 | Miguel-Romero, L, Alqasmi, M, Bacarizo, J, Tan, J.A, Cogdell, R.J, Chen, J, Byron, O, Christie, G.E, Marina, A, Penades, J.R. | | 登録日 | 2021-07-10 | | 公開日 | 2022-07-27 | | 最終更新日 | 2022-11-16 | | 実験手法 | X-RAY DIFFRACTION (2.901 Å) | | 主引用文献 | Non-canonical Staphylococcus aureus pathogenicity island repression.
Nucleic Acids Res., 50, 2022
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7PMU
 | | Crystal structure of native Iripin-8 | | 分子名称: | DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, Serpin-8, ... | | 著者 | Polderdijk, S, Kotal, J, Chmelar, J, Huntington, J.A. | | 登録日 | 2021-09-02 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Ixodes ricinus Salivary Serpin Iripin-8 Inhibits the Intrinsic Pathway of Coagulation and Complement.
Int J Mol Sci, 22, 2021
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7Q1L
 | | Glycosilated Human Serum Apo-tranferrin | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | | 著者 | Gavira, J.A, Moreno, A, Campos-Escamilla, C, Gonzalez-Ramirez, L.A, Siliqi, D. | | 登録日 | 2021-10-20 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | X-ray Characterization of Conformational Changes of Human Apo- and Holo-Transferrin.
Int J Mol Sci, 22, 2021
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