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7OZG

PMCA-amplified alpha-synuclein fibril polymorph, Parkinson's Disease patient-derived seeds

Summary for 7OZG
Entry DOI10.2210/pdb7ozg/pdb
Related7OZG 7OZH
EMDB information13123 13124
DescriptorAlpha-synuclein (1 entity in total)
Functional Keywordsalpha-synuclein amyloid parkinson's disease pmca amplified, protein fibril
Biological sourceHomo sapiens (Human)
Total number of polymer chains10
Total formula weight144761.08
Authors
Frieg, B.,Geraets, J.A.,Schroeder, G.F. (deposition date: 2021-06-28, release date: 2022-07-13)
Primary citationFrieg, B.,Geraets, J.A.,Strohaeker, T.,Dienemann, C.,Mavroeidi, P.,Jung, B.C.,Woojin, S.K.,Lee, S.-J.,Xilouri, M.,Zweckstetter, M.,Schroeder, G.F.
alpha-synuclein polymorphism determines oligodendroglial dysfunction
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.3 Å)
Structure validation

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