7TNH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tnh by Molmil](/molmil-images/mine/7tnh) | Crystal structure of CSF1R kinase domain in complex with DP-6233 | 分子名称: | 2,2-dimethyl-N-[(6-methyl-5-{[2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl]oxy}pyridin-2-yl)carbamoyl]propanamide, CHLORIDE ION, Macrophage colony-stimulating factor 1 receptor,Fibroblast growth factor receptor 1 chimera, ... | 著者 | Edwards, T.E, Arakaki, T.L, Chun, L, Flynn, D.L. | 登録日 | 2022-01-21 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Discovery of acyl ureas as highly selective small molecule CSF1R kinase inhibitors. Bioorg.Med.Chem.Lett., 74, 2022
|
|
3KYK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3kyk by Molmil](/molmil-images/mine/3kyk) | Crystal structure of li33 Igg1 Fab | 分子名称: | Heavy Chain Li33 IgG1, Light Chain Li33 IgG1, SULFATE ION | 著者 | Silvian, L.F, Pepinsky, R.B, Walus, L. | 登録日 | 2009-12-06 | 公開日 | 2010-03-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Improving the solubility of anti-LINGO-1 monoclonal antibody Li33 by isotype switching and targeted mutagenesis. Protein Sci., 19, 2010
|
|
2KRB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2krb by Molmil](/molmil-images/mine/2krb) | Solution structure of EIF3B-RRM bound to EIF3J peptide | 分子名称: | Eukaryotic translation initiation factor 3 subunit B, Eukaryotic translation initiation factor 3 subunit J | 著者 | Elantak, L, Wagner, S, Herrmannova, A, Janoskova, M, Rutkai, E, Lukavsky, P.J, Valasek, L. | 登録日 | 2009-12-16 | 公開日 | 2010-01-05 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | The indispensable N-terminal half of eIF3j/HCR1 co-operates with
its structurally conserved binding partner eIF3b/PRT1-RRM and eIF1A in
stringent AUG selection To be Published
|
|
1ZAT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zat by Molmil](/molmil-images/mine/1zat) | Crystal Structure of an Enterococcus faecium peptidoglycan binding protein at 2.4 A resolution | 分子名称: | L,D-transpeptidase, SULFATE ION, ZINC ION | 著者 | Biarrotte-Sorin, S, Hugonnet, J.-E, Mainardi, J.-L, Gutmann, L, Rice, L, Arthur, M, Mayer, C. | 登録日 | 2005-04-07 | 公開日 | 2006-03-28 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structure of a Novel beta-Lactam-insensitive Peptidoglycan Transpeptidase. J.Mol.Biol., 359, 2006
|
|
6U7L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u7l by Molmil](/molmil-images/mine/6u7l) | 2.75 Angstrom Crystal Structure of Galactarate Dehydratase from Escherichia coli. | 分子名称: | CALCIUM ION, CHLORIDE ION, Galactarate dehydratase (L-threo-forming) | 著者 | Minasov, G, Shuvalova, L, Wawrzak, Z, Dubrovska, I, Kiryukhina, O, Endres, M, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-09-03 | 公開日 | 2019-11-06 | 最終更新日 | 2021-01-27 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structure of galactarate dehydratase, a new fold in an enolase involved in bacterial fitness after antibiotic treatment. Protein Sci., 29, 2020
|
|
5JBE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jbe by Molmil](/molmil-images/mine/5jbe) | 4,6-alpha-glucanotransferase GTFB from Lactobacillus reuteri 121 complexed with an isomalto-maltopentasaccharide | 分子名称: | ACETATE ION, CALCIUM ION, Inactive glucansucrase, ... | 著者 | Pijning, T, Dijkstra, B.W, Bai, Y, Gangoiti-Munecas, J, Dijkhuizen, L. | 登録日 | 2016-04-13 | 公開日 | 2017-01-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of 4,6-alpha-Glucanotransferase Supports Diet-Driven Evolution of GH70 Enzymes from alpha-Amylases in Oral Bacteria. Structure, 25, 2017
|
|
2KKZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kkz by Molmil](/molmil-images/mine/2kkz) | Solution NMR structure of the monomeric W187R mutant of A/Udorn NS1 effector domain. Northeast Structural Genomics target OR8C[W187R]. | 分子名称: | Non-structural protein NS1 | 著者 | Aramini, J.M, Ma, L, Lee, H, Zhao, L, Cunningham, K, Ciccosanti, C, Janjua, H, Fang, Y, Xiao, R, Krug, R.M, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-06-29 | 公開日 | 2009-07-21 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of the monomeric W187R mutant of A/Udorn NS1 effector domain. Northeast Structural Genomics target OR8C[W187R]. To be Published
|
|
3HYK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hyk by Molmil](/molmil-images/mine/3hyk) | 2.31 Angstrom resolution crystal structure of a holo-(acyl-carrier-protein) synthase from Bacillus anthracis str. Ames in complex with CoA (3',5'-ADP) | 分子名称: | ADENOSINE-3'-5'-DIPHOSPHATE, CHLORIDE ION, Holo-[acyl-carrier-protein] synthase, ... | 著者 | Halavaty, A.S, Minasov, G, Skarina, T, Onopriyenko, O, Papazisi, L, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2009-06-22 | 公開日 | 2009-06-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Structural characterization and comparison of three acyl-carrier-protein synthases from pathogenic bacteria. Acta Crystallogr.,Sect.D, 68, 2012
|
|
2GMP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gmp by Molmil](/molmil-images/mine/2gmp) | Metal-free (apo) P. angolensis seed lectin in complex with GlcNAC-beta(1-2)Man | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, SULFATE ION, lectin | 著者 | Garcia-Pino, A, Buts, L, Wyns, L, Loris, R. | 登録日 | 2006-04-07 | 公開日 | 2006-07-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Interplay Between Metal Binding and cis/trans Isomerization in Legume Lectins: Structural and Thermodynamic Study of P. angolensis Lectin. J.Mol.Biol., 361, 2006
|
|
2GNT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gnt by Molmil](/molmil-images/mine/2gnt) | EDTA treated P. angolensis lectin (PAL) remetallized with calcium (1 hour treatment) | 分子名称: | CALCIUM ION, lectin | 著者 | Garcia-Pino, A, Buts, L, Wyns, L, Loris, R. | 登録日 | 2006-04-11 | 公開日 | 2006-07-25 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Interplay Between Metal Binding and cis/trans Isomerization in Legume Lectins: Structural and Thermodynamic Study of P. angolensis Lectin. J.Mol.Biol., 361, 2006
|
|
6SZE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6sze by Molmil](/molmil-images/mine/6sze) | |
6SLK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6slk by Molmil](/molmil-images/mine/6slk) | Diaminobutyrate acetyltransferase EctA from Paenibacillus lautus | 分子名称: | L-2,4-diaminobutyric acid acetyltransferase, SODIUM ION, SULFATE ION | 著者 | Richter, A.A, Kobus, S, Czech, L, Hoeppner, A, Bremer, E, Smits, S.H.J. | 登録日 | 2019-08-20 | 公開日 | 2020-01-29 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The architecture of the diaminobutyrate acetyltransferase active site provides mechanistic insight into the biosynthesis of the chemical chaperone ectoine. J.Biol.Chem., 295, 2020
|
|
7CCF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ccf by Molmil](/molmil-images/mine/7ccf) | Mechanism insights on steroselective oxidation of phosphorylated ethylphenols with cytochrome P450 CreJ | 分子名称: | (3-ethylphenyl) dihydrogen phosphate, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Dong, S, Du, L, Li, S.Y, Feng, Y.G. | 登録日 | 2020-06-17 | 公開日 | 2021-03-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Basis for Selective Oxidation of Phosphorylated Ethylphenols by Cytochrome P450 Monooxygenase CreJ. Appl.Environ.Microbiol., 87, 2021
|
|
6HKQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hkq by Molmil](/molmil-images/mine/6hkq) | Human GPX4 in complex with covalent Inhibitor ML162 (S enantiomer) | 分子名称: | (2~{S})-2-[2-chloranylethanoyl-(3-chloranyl-4-methoxy-phenyl)amino]-~{N}-(2-phenylethyl)-2-thiophen-2-yl-ethanamide, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... | 著者 | Hillig, R.C, Moosmayer, D, Hilpmann, A, Hoffmann, L, Schnirch, L, Eaton, J.K, Badock, V, Gradl, S. | 登録日 | 2018-09-07 | 公開日 | 2020-04-01 | 最終更新日 | 2022-12-07 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162. Acta Crystallogr D Struct Biol, 77, 2021
|
|
3HZF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hzf by Molmil](/molmil-images/mine/3hzf) | Structure of TR-alfa bound to selective thyromimetic GC-1 in C2 space group | 分子名称: | Thyroid hormone receptor, alpha isoform 1 variant, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid | 著者 | Aparicio, R, Bleicher, L, Polikarpov, I. | 登録日 | 2009-06-23 | 公開日 | 2009-07-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms. Bmc Struct.Biol., 8, 2008
|
|
2GME
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gme by Molmil](/molmil-images/mine/2gme) | Metal-free (apo) P. angolensis seed lectin | 分子名称: | SULFATE ION, lectin | 著者 | Garcia-Pino, A, Buts, L, Wyns, L, Loris, R. | 登録日 | 2006-04-06 | 公開日 | 2006-07-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Interplay Between Metal Binding and cis/trans Isomerization in Legume Lectins: Structural and Thermodynamic Study of P. angolensis Lectin. J.Mol.Biol., 361, 2006
|
|
2GNM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gnm by Molmil](/molmil-images/mine/2gnm) | P. angolensis lectin (PAL) treated with EDTA for 39 hours | 分子名称: | CALCIUM ION, MANGANESE (II) ION, alpha-D-mannopyranose, ... | 著者 | Garcia-Pino, A, Buts, L, Wyns, L, Loris, R. | 登録日 | 2006-04-10 | 公開日 | 2006-07-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Interplay Between Metal Binding and cis/trans Isomerization in Legume Lectins: Structural and Thermodynamic Study of P. angolensis Lectin. J.Mol.Biol., 361, 2006
|
|
2GMM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gmm by Molmil](/molmil-images/mine/2gmm) | Metal-free (apo) P. angolensis seed lectin in complex with Man-alpha(1-2)Man | 分子名称: | SULFATE ION, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose, lectin | 著者 | Garcia-Pino, A, Buts, L, Wyns, L, Loris, R. | 登録日 | 2006-04-07 | 公開日 | 2006-07-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Interplay Between Metal Binding and cis/trans Isomerization in Legume Lectins: Structural and Thermodynamic Study of P. angolensis Lectin. J.Mol.Biol., 361, 2006
|
|
2GND
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gnd by Molmil](/molmil-images/mine/2gnd) | One hour EDTA treatment, P. angolensis lectin | 分子名称: | CALCIUM ION, MANGANESE (II) ION, alpha-D-mannopyranose, ... | 著者 | Garcia-Pino, A, Buts, L, Wyns, L, Loris, R. | 登録日 | 2006-04-10 | 公開日 | 2006-07-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Interplay Between Metal Binding and cis/trans Isomerization in Legume Lectins: Structural and Thermodynamic Study of P. angolensis Lectin. J.Mol.Biol., 361, 2006
|
|
3L8W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3l8w by Molmil](/molmil-images/mine/3l8w) | Urate oxidase from aspergillus flavus complexed with xanthin | 分子名称: | SODIUM ION, Uricase, XANTHINE, ... | 著者 | Prange, T, Gabison, L, Colloc'h, N, Chiadmi, M. | 登録日 | 2010-01-04 | 公開日 | 2010-06-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Near-atomic resolution structures of urate oxidase complexed with its substrate and analogues: the protonation state of the ligand. Acta Crystallogr.,Sect.D, 66, 2010
|
|
3LAY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3lay by Molmil](/molmil-images/mine/3lay) | Alpha-Helical barrel formed by the decamer of the zinc resistance-associated protein (STM4172) from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 | 分子名称: | Zinc resistance-associated protein | 著者 | Filippova, E.V, Minasov, G, Shuvalova, L, Winsor, J, Dubrovska, I, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-01-07 | 公開日 | 2010-01-19 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Alpha-Helical barrel formed by the decamer of the zinc resistance-associated protein (STM4172) from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 To be Published
|
|
3LBF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3lbf by Molmil](/molmil-images/mine/3lbf) | Crystal structure of Protein L-isoaspartyl methyltransferase from Escherichia coli | 分子名称: | GLYCEROL, PHOSPHATE ION, Protein-L-isoaspartate O-methyltransferase, ... | 著者 | Fang, P, Li, X, Wang, J, Niu, L, Teng, M. | 登録日 | 2010-01-08 | 公開日 | 2010-09-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of the protein L-isoaspartyl methyltransferase from Escherichia coli Cell Biochem.Biophys., 58, 2010
|
|
6RQA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rqa by Molmil](/molmil-images/mine/6rqa) | Crystal structure of the iminosuccinate reductase of Paracoccus denitrificans in complex with NAD+ | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TERBIUM(III) ION, Tb-Xo4, ... | 著者 | Zarzycki, J, Severi, F, Schada von Borzyskowski, L, Erb, T.J. | 登録日 | 2019-05-15 | 公開日 | 2019-08-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Marine Proteobacteria metabolize glycolate via the beta-hydroxyaspartate cycle. Nature, 575, 2019
|
|
2GWG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gwg by Molmil](/molmil-images/mine/2gwg) | Crystal Structure of 4-Oxalomesaconate Hydratase, LigJ, from Rhodopseudomonas palustris, Northeast Structural Genomics Target RpR66. | 分子名称: | 4-oxalomesaconate hydratase, ZINC ION | 著者 | Forouhar, F, Abashidze, M, Jayaraman, S, Cunningham, K, Ciao, M, Ma, L, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-05-04 | 公開日 | 2006-05-23 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of 4-Oxalomesaconate Hydratase, LigJ, from Rhodopseudomonas palustris, Northeast Structural Genomics Target RpR66 To be Published
|
|
2GN7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gn7 by Molmil](/molmil-images/mine/2gn7) | Metal-free (apo) P. angolensis seed lectin in complex with Man-alpha(1-3)Man-alpha(1-6)Man | 分子名称: | alpha-D-mannopyranose, beta-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose, lectin | 著者 | Garcia-Pino, A, Buts, L, Wyns, L, Loris, R. | 登録日 | 2006-04-09 | 公開日 | 2006-07-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Interplay Between Metal Binding and cis/trans Isomerization in Legume Lectins: Structural and Thermodynamic Study of P. angolensis Lectin. J.Mol.Biol., 361, 2006
|
|