7X0T
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7X0Z
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7X07
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7XEC
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7X1W
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4R3M
| Crystal structure of Human Hsp90 with JR9 | 分子名称: | Heat shock protein HSP 90-alpha, N~3~-benzyl-2-[(6-bromo-1,3-benzodioxol-5-yl)methyl]imidazo[1,2-a]pyrazine-3,8-diamine | 著者 | Li, J, Yang, M, Ren, J, Xiong, B, He, J. | 登録日 | 2014-08-16 | 公開日 | 2014-11-05 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Multi-substituted 8-aminoimidazo[1,2-a]pyrazines by Groebke-Blackburn-Bienayme reaction and their Hsp90 inhibitory activity. Org.Biomol.Chem., 13, 2015
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1PU4
| Crystal structure of human vascular adhesion protein-1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Salminen, T.A, Airenne, T.T. | 登録日 | 2003-06-24 | 公開日 | 2005-05-03 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structure of the human vascular adhesion protein-1: unique structural features with functional implications. Protein Sci., 14, 2005
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1M1C
| Structure of the L-A virus | 分子名称: | Major coat protein | 著者 | Naitow, H, Tang, J, Canady, M, Wickner, R.B, Johnson, J.E. | 登録日 | 2002-06-18 | 公開日 | 2002-10-02 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | L-A virus at 3.4 A resolution reveals particle architecture and mRNA decapping mechanism. Nat.Struct.Biol., 9, 2002
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3LZE
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2MB9
| Human Bcl10 CARD | 分子名称: | B-cell lymphoma/leukemia 10 | 著者 | Zheng, C, Bracken, C, Wu, H. | 登録日 | 2013-07-26 | 公開日 | 2013-10-16 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Architecture of the CARMA1/Bcl10/MALT1 Signalosome: Nucleation-Induced Filamentous Assembly. Mol.Cell, 51, 2013
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7JNI
| Crystal structure of the angiotensin II type 2 receptoror (AT2R) in complex with EMA401 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, FORMIC ACID, HEXANE-1,6-DIOL, ... | 著者 | Cherezov, V, Shaye, H, Han, G.W. | 登録日 | 2020-08-04 | 公開日 | 2022-02-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Inhibition of the angiotensin II type 2 receptor AT 2 R is a novel therapeutic strategy for glioblastoma. Proc.Natl.Acad.Sci.USA, 119, 2022
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7AUV
| The structure of ERK2 in complex with dual inhibitor ASTX029 | 分子名称: | (2~{R})-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]-~{N}-[(1~{S})-1-(3-fluoranyl-5-methoxy-phenyl)-2-oxidanyl-ethyl]propanamide, DIMETHYL SULFOXIDE, Mitogen-activated protein kinase 1, ... | 著者 | O'Reilly, M. | 登録日 | 2020-11-03 | 公開日 | 2021-10-06 | 最終更新日 | 2021-10-13 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | ASTX029, a Novel Dual-mechanism ERK Inhibitor, Modulates Both the Phosphorylation and Catalytic Activity of ERK. Mol.Cancer Ther., 20, 2021
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7XUP
| Crystal structure of TPe3.0 | 分子名称: | Transcriptional regulator, PadR-like family | 著者 | Chen, X, Qian, J.Y, Sun, N.N, Zhong, F.R, Wu, Y.Z. | 登録日 | 2022-05-19 | 公開日 | 2022-09-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | 主引用文献 | Enantioselective [2+2]-cycloadditions with triplet photoenzymes. Nature, 611, 2022
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7XUQ
| Crystal structure of Tpe3.0 complexed with N-Boc-3-alkenylindole | 分子名称: | Transcriptional regulator, PadR-like family, dimethyl 2-[[2-methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]methyl]-2-prop-2-enyl-propanedioate | 著者 | Chen, X, Qian, J.Y, Sun, N.N, Zhong, F.R, Wu, Y.Z. | 登録日 | 2022-05-19 | 公開日 | 2022-09-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Enantioselective [2+2]-cycloadditions with triplet photoenzymes. Nature, 611, 2022
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1D5L
| CRYSTAL STRUCTURE OF CYANIDE-BOUND HUMAN MYELOPEROXIDASE ISOFORM C AT PH 5.5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | 著者 | Fiedler, T.J, Davey, C.A, Fenna, R.E. | 登録日 | 1999-10-07 | 公開日 | 2001-12-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Human myeloperoxidase: structure of a cyanide complex and its interaction with bromide and thiocyanate substrates at 1.9 A resolution. Biochemistry, 40, 2001
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1CXP
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3Q01
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3OQ1
| Crystal Structure of 11beta-Hydroxysteroid Dehydrogenase-1 (11b-HSD1) in Complex with Diarylsulfone Inhibitor | 分子名称: | 3-(2-fluoroethyl)-4-({4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]phenyl}sulfonyl)benzonitrile, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Wang, Z, Sudom, A, Walker, N.P. | 登録日 | 2010-09-02 | 公開日 | 2011-07-20 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The synthesis and SAR of novel diarylsulfone 11beta-HSD1 inhibitors Bioorg.Med.Chem.Lett., 20, 2010
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1D7W
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3M4P
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3Q05
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7MB9
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7MB7
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7MB4
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7MB8
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