7K17
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k17 by Molmil](/molmil-images/mine/7k17) | |
3RAU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rau by Molmil](/molmil-images/mine/3rau) | Crystal structure of the HD-PTP Bro1 domain | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ... | 著者 | Mu, R.L, Jiang, J.S, Snyder, G, Smith, P, Xiao, T. | 登録日 | 2011-03-28 | 公開日 | 2011-09-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The Phe105 Loop of Alix Bro1 Domain Plays a Key Role in HIV-1 Release. Structure, 19, 2011
|
|
3R9M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3r9m by Molmil](/molmil-images/mine/3r9m) | Crystal structure of the Brox Bro1 domain | 分子名称: | 1,2-ETHANEDIOL, BRO1 domain-containing protein BROX, FORMIC ACID | 著者 | Mu, R.L, Jiang, J.S, Snyder, G, Smith, P, Xiao, T. | 登録日 | 2011-03-25 | 公開日 | 2011-09-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The Phe105 Loop of Alix Bro1 Domain Plays a Key Role in HIV-1 Release. Structure, 19, 2011
|
|
5LA7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5la7 by Molmil](/molmil-images/mine/5la7) | Crystal structure of human proheparanase, in complex with glucuronic acid configured aziridine probe JJB355 | 分子名称: | (1~{S},2~{R},3~{S},4~{S},5~{S},6~{R})-2-(8-azidooctylamino)-3,4,5,6-tetrakis(oxidanyl)cyclohexane-1-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wu, L, Jin, Y, Davies, G.J. | 登録日 | 2016-06-13 | 公開日 | 2017-05-31 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Activity-based probes for functional interrogation of retaining beta-glucuronidases. Nat. Chem. Biol., 13, 2017
|
|
5L9Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5l9y by Molmil](/molmil-images/mine/5l9y) | Crystal structure of human heparanase, in complex with glucuronic acid configured aziridine probe JJB355 | 分子名称: | (1~{S},2~{R},3~{S},4~{S},5~{S},6~{R})-2-(8-azidooctylamino)-3,4,5,6-tetrakis(oxidanyl)cyclohexane-1-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wu, L, Jin, Y, Davies, G.J. | 登録日 | 2016-06-13 | 公開日 | 2017-05-31 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Activity-based probes for functional interrogation of retaining beta-glucuronidases. Nat. Chem. Biol., 13, 2017
|
|
3T0T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3t0t by Molmil](/molmil-images/mine/3t0t) | Crystal structure of S. aureus Pyruvate Kinase | 分子名称: | N'-[(1E)-1-(1H-benzimidazol-2-yl)ethylidene]-5-bromo-2-hydroxybenzohydrazide, PHOSPHATE ION, Pyruvate kinase | 著者 | Worrall, L.J, Vuckovic, M, Strynadka, N.C.J. | 登録日 | 2011-07-20 | 公開日 | 2012-06-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Cheminformatics-driven discovery of selective, nanomolar inhibitors for staphylococcal pyruvate kinase. Acs Chem.Biol., 7, 2012
|
|
3B1B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3b1b by Molmil](/molmil-images/mine/3b1b) | |
5EMY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5emy by Molmil](/molmil-images/mine/5emy) | Human Pancreatic Alpha-Amylase in complex with the mechanism based inactivator glucosyl epi-cyclophellitol | 分子名称: | (1R,2R,3S,5R,6S)-2,3,5-trihydroxy-6-(hydroxymethyl)cyclohexyl alpha-D-glucopyranoside, CALCIUM ION, CHLORIDE ION, ... | 著者 | Caner, S, Brayer, G.D. | 登録日 | 2015-11-06 | 公開日 | 2016-07-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.231 Å) | 主引用文献 | Glucosyl epi-cyclophellitol allows mechanism-based inactivation and structural analysis of human pancreatic alpha-amylase. Febs Lett., 590, 2016
|
|
5FOO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5foo by Molmil](/molmil-images/mine/5foo) | 6-phospho-beta-glucosidase | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-PHOSPHO-BETA-D GLYCOSIDASE, ... | 著者 | Jin, Y, Kwan, D.H, Withers, S.G, Davies, G.J. | 登録日 | 2015-11-24 | 公開日 | 2016-02-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Chemoenzymatic Synthesis of 6-Phospho-Cyclophellitol as a Novel Probe of 6-Phospho-Beta-Glucosidases. FEBS Lett., 590, 2016
|
|
7X5V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7x5v by Molmil](/molmil-images/mine/7x5v) | |
5VKZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vkz by Molmil](/molmil-images/mine/5vkz) | Crystal structure of Mdm12 and combinatorial reconstitution of Mdm12/Mmm1 ERMES complexes for structural studies | 分子名称: | Mitochondrial distribution and morphology protein 12 | 著者 | Egea, P.F, AhYoung, A.P, Lu, B, Tan, H.R, Cascio, D. | 登録日 | 2017-04-24 | 公開日 | 2017-07-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | 主引用文献 | Crystal structure of Mdm12 and combinatorial reconstitution of Mdm12/Mmm1 ERMES complexes for structural studies. Biochem. Biophys. Res. Commun., 488, 2017
|
|
4P6A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4p6a by Molmil](/molmil-images/mine/4p6a) | Crystal structure of a potent anti-HIV lectin actinohivin in complex with alpha-1,2-mannotriose | 分子名称: | Actinohivin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose | 著者 | Zhang, F, Hoque, M.M, Suzuki, K, Tsunoda, M, Naomi, O, Tanaka, H, Takenaka, A. | 登録日 | 2014-03-23 | 公開日 | 2015-03-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.398 Å) | 主引用文献 | The characteristic structure of anti-HIV actinohivin in complex with three HMTG D1 chains of HIV-gp120. Chembiochem, 15, 2014
|
|
3VD8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3vd8 by Molmil](/molmil-images/mine/3vd8) | Crystal structure of human AIM2 PYD domain with MBP fusion | 分子名称: | 1,2-ETHANEDIOL, Maltose-binding periplasmic protein, Interferon-inducible protein AIM2, ... | 著者 | Jin, T.C, Perry, A, Smith, P, Xiao, T.S. | 登録日 | 2012-01-04 | 公開日 | 2013-01-16 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.0685 Å) | 主引用文献 | Structure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome Assembly. J.Biol.Chem., 288, 2013
|
|
6LUI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lui by Molmil](/molmil-images/mine/6lui) | Crystal structure of the SAMD1 WH domain and DNA complex | 分子名称: | Atherin, DNA (5'-D(*AP*CP*CP*TP*GP*CP*GP*CP*AP*CP*CP*AP*T)-3'), DNA (5'-D(*AP*TP*GP*GP*TP*GP*CP*GP*CP*AP*GP*GP*T)-3') | 著者 | Zhou, Y, Cao, Y, Wang, Z. | 登録日 | 2020-01-29 | 公開日 | 2021-02-03 | 最終更新日 | 2021-07-07 | 実験手法 | X-RAY DIFFRACTION (1.781 Å) | 主引用文献 | The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands. Sci Adv, 7, 2021
|
|
6LUJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6luj by Molmil](/molmil-images/mine/6luj) | |
6B9K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b9k by Molmil](/molmil-images/mine/6b9k) | |
6LUK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6luk by Molmil](/molmil-images/mine/6luk) | |
6CI4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ci4 by Molmil](/molmil-images/mine/6ci4) | Crystal structure of the formyltransferase PseJ from Anoxybacillus kamchatkensis soaked with UDP-4-amino-4,6-dideoxy-L-AltNAc | 分子名称: | (2R,3R,4S,5R,6S)-3-(acetylamino)-5-amino-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, formyltransferase PseJ | 著者 | Harb, I, Reimer, J.M, Schmeing, T.M. | 登録日 | 2018-02-23 | 公開日 | 2018-10-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.824068 Å) | 主引用文献 | Structural Insight into a Novel Formyltransferase and Evolution to a Nonribosomal Peptide Synthetase Tailoring Domain. ACS Chem. Biol., 13, 2018
|
|
6BK8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6bk8 by Molmil](/molmil-images/mine/6bk8) | S. cerevisiae spliceosomal post-catalytic P complex | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Lea1, ... | 著者 | Liu, S, Li, X, Zhou, Z.H, Zhao, R. | 登録日 | 2017-11-07 | 公開日 | 2018-02-21 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of the yeast spliceosomal postcatalytic P complex. Science, 358, 2017
|
|
6CI5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ci5 by Molmil](/molmil-images/mine/6ci5) | Crystal structure of the formyltransferase PseJ from Anoxybacillus kamchatkensis in complex with UDP-4,6-dideoxy-4-formamido-L-AltNAc and tetrahydrofolate | 分子名称: | (2R,3R,4S,5R,6S)-3-(acetylamino)-5-(formylamino)-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name), N-[4-({[(6R)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, SULFATE ION, ... | 著者 | Reimer, J.M, Harb, I, Schmeing, T.M. | 登録日 | 2018-02-23 | 公開日 | 2018-10-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.00003052 Å) | 主引用文献 | Structural Insight into a Novel Formyltransferase and Evolution to a Nonribosomal Peptide Synthetase Tailoring Domain. ACS Chem. Biol., 13, 2018
|
|
3HA6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ha6 by Molmil](/molmil-images/mine/3ha6) | Crystal structure of aurora A in complex with TPX2 and compound 10 | 分子名称: | N~2~-(3,4-dimethoxyphenyl)-N~4~-[2-(2-fluorophenyl)ethyl]-N~6~-quinolin-6-yl-1,3,5-triazine-2,4,6-triamine, Serine/threonine-protein kinase 6, Targeting protein for Xklp2 | 著者 | Zhao, B, Clark, M.A. | 登録日 | 2009-05-01 | 公開日 | 2009-08-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Design, synthesis and selection of DNA-encoded small-molecule libraries. Nat.Chem.Biol., 5, 2009
|
|
3HA8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ha8 by Molmil](/molmil-images/mine/3ha8) | THE COMPLEX STRUCTURE OF THE MAP KINASE P38/Compound 14b | 分子名称: | Mitogen-activated protein kinase 14, N~2~-{4-[6-(3,4-dihydroquinolin-1(2H)-ylcarbonyl)-1H-benzimidazol-1-yl]-6-ethoxy-1,3,5-triazin-2-yl}-3-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-N-methyl-L-alaninamide | 著者 | Zhao, B, Clark, M.A. | 登録日 | 2009-05-01 | 公開日 | 2009-08-04 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Design, synthesis and selection of DNA-encoded small-molecule libraries. Nat.Chem.Biol., 5, 2009
|
|
3RYT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ryt by Molmil](/molmil-images/mine/3ryt) | |
8J1Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8j1z by Molmil](/molmil-images/mine/8j1z) | |
8J8Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8j8q by Molmil](/molmil-images/mine/8j8q) | Structure of the four-component Paf1 complex from Saccharomyces eubayanus | 分子名称: | CDC73-like protein, CTR9-like protein, PAF1-like protein, ... | 著者 | Wang, Z, Qin, Y, Zhou, Y, Cao, Y. | 登録日 | 2023-05-02 | 公開日 | 2023-05-24 | 最終更新日 | 2023-06-14 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Structural Basis of the Transcriptional Elongation Factor Paf1 Core Complex from Saccharomyces eubayanus . Int J Mol Sci, 24, 2023
|
|