7FHA
 
 | | Crystal structure of the ATP sulfurylase domain of human PAPSS2 in complex with APS | | 分子名称: | ADENOSINE-5'-PHOSPHOSULFATE, Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2, POTASSIUM ION, ... | | 著者 | Zhang, P, Zhang, L, Zhang, L. | | 登録日 | 2021-07-29 | | 公開日 | 2021-12-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for the substrate recognition mechanism of ATP-sulfurylase domain of human PAPS synthase 2.
Biochem.Biophys.Res.Commun., 586, 2022
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7FH3
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7CUQ
 | | 2.55-Angstrom Cryo-EM structure of Cytochrome bo3 from Escherichia coli in Native Membrane | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ... | | 著者 | Li, J, Han, L, Gennis, R.B, Zhu, J.P, Zhang, K. | | 登録日 | 2020-08-24 | | 公開日 | 2021-08-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.64 Å) | | 主引用文献 | Cryo-EM structures of Escherichia coli cytochrome bo3 reveal bound phospholipids and ubiquinone-8 in a dynamic substrate binding site.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7CUB
 | | 2.55-Angstrom Cryo-EM structure of Cytochrome bo3 from Escherichia coli in Native Membrane | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ... | | 著者 | Li, J, Han, L, Gennis, R.B, Zhu, J.P, Zhang, K. | | 登録日 | 2020-08-22 | | 公開日 | 2021-08-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.55 Å) | | 主引用文献 | Cryo-EM structures of Escherichia coli cytochrome bo3 reveal bound phospholipids and ubiquinone-8 in a dynamic substrate binding site.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7CUW
 | | Ubiquinol Binding Site of Cytochrome bo3 from Escherichia coli | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ... | | 著者 | Li, J, Han, L, Gennis, R.B, Zhu, J.P, Zhang, K. | | 登録日 | 2020-08-25 | | 公開日 | 2021-08-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | | 主引用文献 | Cryo-EM structures of Escherichia coli cytochrome bo3 reveal bound phospholipids and ubiquinone-8 in a dynamic substrate binding site.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7EVP
 | | Cryo-EM structure of the Gp168-beta-clamp complex | | 分子名称: | Beta sliding clamp, Sliding clamp inhibitor | | 著者 | Liu, B, Li, S, Liu, Y, Chen, H, Hu, Z, Wang, Z, Gou, L, Zhang, L, Ma, B, Wang, H, Matthews, S, Wang, Y, Zhang, K. | | 登録日 | 2021-05-21 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Bacteriophage Twort protein Gp168 is a beta-clamp inhibitor by occupying the DNA sliding channel.
Nucleic Acids Res., 49, 2021
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5II6
 | | Crystal structure of the ZP-N1 domain of mouse sperm receptor ZP2 at 0.95 A resolution | | 分子名称: | Zona pellucida sperm-binding protein 2 | | 著者 | Dioguardi, E, Han, L, Nishimura, K, De Sanctis, D, Jovine, L. | | 登録日 | 2016-03-01 | | 公開日 | 2017-06-14 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | | 主引用文献 | Structural Basis of Egg Coat-Sperm Recognition at Fertilization.
Cell, 169, 2017
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6IUV
 | | Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody 3C11 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 3C11 Heavy Chain, 3C11 Light Chain, ... | | 著者 | Wang, P, Zuo, Y, Sun, J, Zhang, L, Wang, X. | | 登録日 | 2018-11-30 | | 公開日 | 2019-01-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.332 Å) | | 主引用文献 | Structural and functional definition of a vulnerable site on the hemagglutinin of highly pathogenic avian influenza A virus H5N1.
J. Biol. Chem., 294, 2019
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5B5K
 | | Crystal structure of Izumo1, the mammalian sperm ligand for egg Juno | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Izumo sperm-egg fusion protein 1 | | 著者 | Nishimura, K, Han, L, De Sanctis, D, Jovine, L. | | 登録日 | 2016-05-11 | | 公開日 | 2016-07-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The structure of sperm Izumo1 reveals unexpected similarities with Plasmodium invasion proteins.
Curr.Biol., 26, 2016
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6J5I
 | | Cryo-EM structure of the mammalian DP-state ATP synthase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F1 subunit epsilon, ... | | 著者 | Gu, J, Zhang, L, Yi, J, Yang, M. | | 登録日 | 2019-01-11 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | | 主引用文献 | Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1.
Science, 364, 2019
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6J54
 | | Cryo-EM structure of the mammalian E-state ATP synthase FO section | | 分子名称: | ATP synthase membrane subunit 6.8PL, ATP synthase membrane subunit DAPIT, ATP synthase peripheral stalk-membrane subunit b, ... | | 著者 | Gu, J, Zhang, L, Yi, J, Yang, M. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.94 Å) | | 主引用文献 | Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1.
Science, 364, 2019
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6J5A
 | | Cryo-EM structure of the mammalian DP-state ATP synthase FO section | | 分子名称: | ATP synthase membrane subunit 6.8PL, ATP synthase membrane subunit DAPIT, ATP synthase peripheral stalk-membrane subunit b, ... | | 著者 | Gu, J, Zhang, L, Yi, J, Yang, M. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.35 Å) | | 主引用文献 | Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1.
Science, 364, 2019
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6IZO
 | | Crystal structure of DNA polymerase sliding clamp from Caulobacter crescentus | | 分子名称: | 1,2-ETHANEDIOL, Beta sliding clamp, DI(HYDROXYETHYL)ETHER | | 著者 | Jiang, X, Zhang, L, Teng, M, Li, X. | | 登録日 | 2018-12-20 | | 公開日 | 2019-11-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Caulobacter crescentus beta sliding clamp employs a noncanonical regulatory model of DNA replication.
Febs J., 287, 2020
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6J5K
 | | Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F1 subunit alpha, ... | | 著者 | Gu, J, Zhang, L, Yi, J, Yang, M. | | 登録日 | 2019-01-11 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | | 主引用文献 | Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1.
Science, 364, 2019
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7E6T
 | | Structural insights into the activation of human calcium-sensing receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CYCLOMETHYLTRYPTOPHAN, ... | | 著者 | Geng, Y, Chen, X.C, Wang, L, Cui, Q.Q, Ding, Z.Y, Han, L, Kou, Y.J, Zhang, W.Q, Wang, H.N, Jia, X.M, Dai, M, Shi, Z.Z, Li, Y.Y, Li, X.Y. | | 登録日 | 2021-02-24 | | 公開日 | 2021-09-22 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural insights into the activation of human calcium-sensing receptor.
Elife, 10, 2021
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7E6U
 | | the complex of inactive CaSR and NB2D11 | | 分子名称: | Extracellular calcium-sensing receptor, NB-2D11 | | 著者 | Geng, Y, Chen, X.C, Wang, L, Cui, Q.Q, Ding, Z.Y, Han, L, Kou, Y.J, Zhang, W.Q, Wang, H.N, Jia, X.M, Dai, M, Shi, Z.Z, Li, Y.Y, Li, X.Y. | | 登録日 | 2021-02-24 | | 公開日 | 2021-09-22 | | 実験手法 | ELECTRON MICROSCOPY (6 Å) | | 主引用文献 | Structural insights into the activation of human calcium-sensing receptor.
Elife, 10, 2021
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4JNM
 | | Discovery of Potent and Efficacious Urea-containing Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors with Reduced CYP2C9 Inhibition Properties | | 分子名称: | 1,2-ETHANEDIOL, 1-[(6-aminopyridin-3-yl)methyl]-3-[4-(phenylsulfonyl)phenyl]urea, Nicotinamide phosphoribosyltransferase, ... | | 著者 | Gunzner-Toste, J, Zhao, G, Bauer, P, Baumeister, T, Buckmelter, A.J, Caligiuri, M, Clodfelter, K.H, Fu, B, Han, B, Ho, Y, Kley, N, Liederer, B, Lin, J, Mukadam, S, O'Brien, T, Reynolds, D.J, Sharma, G, Skelton, N, Smith, C.C, Oh, A, Wang, W, Wang, Z, Xiao, Y, Yuen, P, Zak, M, Zhang, L, Zheng, X, Bair, K.W, Dragovich, P.S. | | 登録日 | 2013-03-15 | | 公開日 | 2013-05-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties.
Bioorg.Med.Chem.Lett., 23, 2013
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5U8K
 | | RitR mutant - C128S | | 分子名称: | Response regulator | | 著者 | Silvaggi, N.R, Han, L. | | 登録日 | 2016-12-14 | | 公開日 | 2017-12-20 | | 最終更新日 | 2018-11-28 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization.
PLoS Pathog., 14, 2018
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5IHS
 | | Structure of CHU_2103 from Cytophaga hutchinsonii | | 分子名称: | Endoglucanase, glycoside hydrolase family 5 protein | | 著者 | Silvaggi, N.R, Han, L. | | 登録日 | 2016-02-29 | | 公開日 | 2016-06-22 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Periplasmic Cytophaga hutchinsonii Endoglucanases Are Required for Use of Crystalline Cellulose as the Sole Source of Carbon and Energy.
Appl.Environ.Microbiol., 82, 2016
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7K26
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6AGY
 | | Aspergillus fumigatus Af293 NDK | | 分子名称: | Nucleoside diphosphate kinase | | 著者 | Hu, Y, Han, L. | | 登録日 | 2018-08-15 | | 公開日 | 2019-03-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Characterization of crystal structure and key residues of Aspergillus fumigatus nucleoside diphosphate kinase.
Biochem. Biophys. Res. Commun., 511, 2019
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1E0D
 | | UDP-N-Acetylmuramoyl-L-Alanine:D-Glutamate Ligase | | 分子名称: | SULFATE ION, UDP-N-ACETYLMURAMOYLALANINE--D-GLUTAMATE LIGASE | | 著者 | Fanchon, E, Bertrand, J, Chantalat, L, Dideberg, O. | | 登録日 | 2000-03-24 | | 公開日 | 2000-06-09 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | "Open" Structures of Murd: Domain Movements and Structural Similarities with Folylpolyglutamate Synthetase.
J.Mol.Biol., 301, 2000
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4FGB
 | | Crystal structure of human calcium/calmodulin-dependent protein kinase I apo form | | 分子名称: | Calcium/calmodulin-dependent protein kinase type 1 | | 著者 | Zha, M, Zhong, C, Ou, Y, Wang, J, Han, L, Ding, J. | | 登録日 | 2012-06-04 | | 公開日 | 2013-01-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structures of human CaMKIalpha reveal insights into the regulation mechanism of CaMKI.
Plos One, 7, 2012
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4FG7
 | | Crystal structure of human calcium/calmodulin-dependent protein kinase I 1-293 in complex with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type 1 | | 著者 | Zha, M, Zhong, C, Ou, Y, Wang, J, Han, L, Ding, J. | | 登録日 | 2012-06-04 | | 公開日 | 2013-01-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structures of human CaMKIalpha reveal insights into the regulation mechanism of CaMKI.
Plos One, 7, 2012
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4FG8
 | | Crystal structure of human calcium/calmodulin-dependent protein kinase I 1-315 in complex with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type 1 | | 著者 | Zha, M, Zhong, C, Ou, Y, Wang, J, Han, L, Ding, J. | | 登録日 | 2012-06-04 | | 公開日 | 2013-01-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structures of human CaMKIalpha reveal insights into the regulation mechanism of CaMKI.
Plos One, 7, 2012
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