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Crystal structure of tRNA 2'-phosphotransferase from Mus musculus
分子名称:	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, GLYCINE, ...
著者	Yang, X.Y, Liu, X.H.
登録日	2022-08-21
公開日	2023-07-26
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (2.23 Å)
主引用文献	Structural and biochemical insights into the molecular mechanism of TRPT1 for nucleic acid ADP-ribosylation. Nucleic Acids Res., 51, 2023

7YW3

Crystal structure of tRNA 2'-phosphotransferase from Homo sapiens
分子名称:	1,2-ETHANEDIOL, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate, tRNA 2'-phosphotransferase 1
著者	Yang, X.Y, Liu, X.H.
登録日	2022-08-21
公開日	2023-07-26
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Structural and biochemical insights into the molecular mechanism of TRPT1 for nucleic acid ADP-ribosylation. Nucleic Acids Res., 51, 2023

7YW4

Crystal structure of tRNA 2'-phosphotransferase from Saccharomyces cerevisiae
分子名称:	D(-)-TARTARIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, tRNA 2'-phosphotransferase
著者	Yang, X.Y, Liu, X.H.
登録日	2022-08-21
公開日	2023-07-26
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (2.18 Å)
主引用文献	Structural and biochemical insights into the molecular mechanism of TRPT1 for nucleic acid ADP-ribosylation. Nucleic Acids Res., 51, 2023

5YUD

Flagellin derivative in complex with the NLR protein NAIP5
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, Baculoviral IAP repeat-containing protein 1e, Phase 2 flagellin,Flagellin
著者	Yang, X.R, Yang, F, Wang, W.G, Lin, G.Z.
登録日	2017-11-21
公開日	2018-01-03
最終更新日	2025-06-18
実験手法	ELECTRON MICROSCOPY (4.28 Å)
主引用文献	Structural basis for specific flagellin recognition by the NLR protein NAIP5. Cell Res., 28, 2018

8JFL

PhK holoenzyme in active state, muscle isoform
分子名称:	ADENOSINE-5'-DIPHOSPHATE, FARNESYL, Phosphorylase b kinase gamma catalytic chain, ...
著者	Yang, X.K, Xiao, J.Y.
登録日	2023-05-18
公開日	2024-04-03
最終更新日	2024-04-10
実験手法	ELECTRON MICROSCOPY (2.9 Å)
主引用文献	Architecture and activation of human muscle phosphorylase kinase. Nat Commun, 15, 2024

8JFK

PhK holoenzyme in inactive state, muscle isoform
分子名称:	Calmodulin-1, FARNESYL, Phosphorylase b kinase gamma catalytic chain, ...
著者	Yang, X.K, Xiao, J.Y.
登録日	2023-05-18
公開日	2024-04-03
最終更新日	2024-11-06
実験手法	ELECTRON MICROSCOPY (2.9 Å)
主引用文献	Architecture and activation of human muscle phosphorylase kinase. Nat Commun, 15, 2024

3AJF

Structural insigths into dsRNA binding and RNA silencing suppression by NS3 protein of rice hoja blanca tenuivirus
分子名称:	Non-structural protein 3, SULFATE ION
著者	Yuan, Y.A.
登録日	2010-06-05
公開日	2011-04-20
最終更新日	2024-10-16
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Structural implications into dsRNA binding and RNA silencing suppression by NS3 protein of Rice Hoja Blanca Tenuivirus Rna, 17, 2011

5YTX

Crystal structure of YB1 cold-shock domain in complex with UCAACU
分子名称:	Nuclease-sensitive element-binding protein 1, RNA (5'-R(PUPCPAPAPCPU)-3')
著者	Yang, X, Huang, Y.
登録日	2017-11-20
公開日	2018-12-05
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.551 Å)
主引用文献	Crystal structure of a Y-box binding protein 1 (YB-1)-RNA complex reveals key features and residues interacting with RNA. J.Biol.Chem., 294, 2019

5YTT

Crystal structure of YB1 cold-shock domain in complex with UCAUGU
分子名称:	Nuclease-sensitive element-binding protein 1, RNA (5'-R(PUPCPAPUPGPU)-3'), SULFATE ION
著者	Yang, X, Huang, Y.
登録日	2017-11-20
公開日	2018-12-05
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	Crystal structure of a Y-box binding protein 1 (YB-1)-RNA complex reveals key features and residues interacting with RNA. J.Biol.Chem., 294, 2019

5YTV

Crystal structure of YB1 cold-shock domain in complex with UCAUCU
分子名称:	Nuclease-sensitive element-binding protein 1, RNA (5'-R(PUPCPAPUPCPU)-3')
著者	Yang, X, Huang, Y.
登録日	2017-11-20
公開日	2018-12-05
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Crystal structure of a Y-box binding protein 1 (YB-1)-RNA complex reveals key features and residues interacting with RNA. J.Biol.Chem., 294, 2019

5YTS

Crystal structure of YB1 cold-shock domain in complex with UCUUCU
分子名称:	Nuclease-sensitive element-binding protein 1, RNA (5'-R(PCPUPUPC)-3'), SULFATE ION
著者	Yang, X, Huang, Y.
登録日	2017-11-20
公開日	2018-12-05
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.77 Å)
主引用文献	Crystal structure of a Y-box binding protein 1 (YB-1)-RNA complex reveals key features and residues interacting with RNA. J.Biol.Chem., 294, 2019

8XYB

hPhK gamma-delta subcomplex in inactive state
分子名称:	Calmodulin-1, FARNESYL, Phosphorylase b kinase gamma catalytic chain, ...
著者	Yang, X.K, Xiao, J.Y.
登録日	2024-01-19
公開日	2024-04-03
最終更新日	2024-04-10
実験手法	ELECTRON MICROSCOPY (3.1 Å)
主引用文献	Architecture and activation of human muscle phosphorylase kinase. Nat Commun, 15, 2024

8XY7

hPhK alpha-gamma subcomplex in active state
分子名称:	FARNESYL, Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform, ...
著者	Yang, X.K, Xiao, J.Y.
登録日	2024-01-19
公開日	2024-04-03
最終更新日	2024-04-10
実験手法	ELECTRON MICROSCOPY (2.9 Å)
主引用文献	Architecture and activation of human muscle phosphorylase kinase. Nat Commun, 15, 2024

8XYA

hPhK alpha-beta-gamma-delta subcomplex in inactive state
分子名称:	Calmodulin-1, FARNESYL, Phosphorylase b kinase gamma catalytic chain, ...
著者	Yang, X.K, Xiao, J.Y.
登録日	2024-01-19
公開日	2024-04-03
最終更新日	2024-04-10
実験手法	ELECTRON MICROSCOPY (2.7 Å)
主引用文献	Architecture and activation of human muscle phosphorylase kinase. Nat Commun, 15, 2024

5ZOL

Crystal structure of a three sites mutantion of FSAA complexed with HA and product
分子名称:	(3S,4S)-3,4-dihydroxy-4-(thiophen-2-yl)butan-2-one, 1-hydroxypropan-2-one, CHLORIDE ION, ...
著者	Wu, L, Yang, X.H, Yu, H.W, Zhou, J.H.
登録日	2018-04-13
公開日	2019-06-12
最終更新日	2024-10-23
実験手法	X-RAY DIFFRACTION (2.172 Å)
主引用文献	The engineering of decameric d-fructose-6-phosphate aldolase A by combinatorial modulation of inter- and intra-subunit interactions. Chem.Commun.(Camb.), 56, 2020

7WV9

Allosteric modulator ZCZ011 binding to CP55940-bound cannabinoid receptor 1 in complex with Gi protein
分子名称:	2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol, 6-methyl-3-[(1S)-2-nitro-1-thiophen-2-yl-ethyl]-2-phenyl-1H-indole, Cannabinoid receptor 1, ...
著者	Xu, Z, Shao, Z.
登録日	2022-02-10
公開日	2022-06-15
最終更新日	2024-11-13
実験手法	ELECTRON MICROSCOPY (3.36 Å)
主引用文献	Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1. Nat.Chem.Biol., 18, 2022

7W8N

Microbial Hormone-sensitive lipase E53 wild type
分子名称:	(4-nitrophenyl) hexanoate, 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, ...
著者	Yang, X, Li, Z, Xu, X, Li, J.
登録日	2021-12-08
公開日	2022-02-23
最終更新日	2025-03-12
実験手法	X-RAY DIFFRACTION (1.75 Å)
主引用文献	Mechanism and Structural Insights Into a Novel Esterase, E53, Isolated From Erythrobacter longus . Front Microbiol, 12, 2021

7CI0

Microbial Hormone-sensitive lipase E53 mutant S162A
分子名称:	1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
著者	Yang, X, Li, Z, Xu, X, Li, J.
登録日	2020-07-06
公開日	2021-07-14
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Mechanism and Structural Insights Into a Novel Esterase, E53, Isolated From Erythrobacter longus . Front Microbiol, 12, 2021

7CIH

Microbial Hormone-sensitive lipase E53 mutant S285G
分子名称:	(4-nitrophenyl) hexanoate, 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, ...
著者	Yang, X, Li, Z, Xu, X, Li, J.
登録日	2020-07-07
公開日	2021-07-14
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (1.789 Å)
主引用文献	Mechanism and Structural Insights Into a Novel Esterase, E53, Isolated From Erythrobacter longus . Front Microbiol, 12, 2021

8H3S

Substrate-bound EP, polyA model
分子名称:	Enteropeptidase catalytic light chain, Enteropeptidase non-catalytic heavy chain, Serine protease 1
著者	Ding, Z.Y, Huang, H.J.
登録日	2022-10-09
公開日	2022-11-23
最終更新日	2025-07-02
実験手法	ELECTRON MICROSCOPY (4.9 Å)
主引用文献	Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022

8H3U

Inhibitor-bound EP, polyA model
分子名称:	Enteropeptidase catalytic light chain, Enteropeptidase non-catalytic heavy chain
著者	Ding, Z.Y, Huang, H.J.
登録日	2022-10-09
公開日	2022-11-23
最終更新日	2025-07-02
実験手法	ELECTRON MICROSCOPY (4.7 Å)
主引用文献	Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022

7WDK

The structure of PldA-PA3488 complex
分子名称:	Phospholipase D, Tli4_C domain-containing protein
著者	Zhao, L, Yang, X.Y, Li, Z.Q.
登録日	2021-12-21
公開日	2022-10-26
最終更新日	2025-06-25
実験手法	ELECTRON MICROSCOPY (3.05 Å)
主引用文献	Structural insights into PA3488-mediated inactivation of Pseudomonas aeruginosa PldA Nat Commun, 13, 2022

7WQZ

Structure of Active-mutEP
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Enteropeptidase catalytic light chain, Enteropeptidase non-catalytic heavy chain
著者	Yang, X.L, Ding, Z.Y, Huang, H.J.
登録日	2022-01-26
公開日	2022-10-26
最終更新日	2025-06-18
実験手法	ELECTRON MICROSCOPY (3.7 Å)
主引用文献	Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022

7WQW

Structure of Active-EP
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Enteropeptidase catalytic light chain, Enteropeptidase non-catalytic heavy chain
著者	Yang, X.L, Ding, Z.Y, Huang, H.J.
登録日	2022-01-26
公開日	2022-10-26
最終更新日	2025-07-02
実験手法	ELECTRON MICROSCOPY (3.2 Å)
主引用文献	Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022

7WQX

Structure of Inactive-EP
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Enteropeptidase
著者	Yang, X.L, Ding, Z.Y, Huang, H.J.
登録日	2022-01-26
公開日	2022-10-26
最終更新日	2025-07-02
実験手法	ELECTRON MICROSCOPY (2.7 Å)
主引用文献	Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022

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