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5A1N
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BU of 5a1n by Molmil
The crystal structure of the GST-like domains complex of EPRS-AIMP2 mutant S156D
分子名称: AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 2, BIFUNCTIONAL GLUTAMATE/PROLINE--TRNA LIGASE, GLYCEROL
著者Cho, H.Y, Choi, Y.S, Kang, B.S.
登録日2015-05-03
公開日2016-06-01
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Symmetric Assembly of a Decameric Subcomplex in Human Multi-tRNA Synthetase Complex Via Interactions between Glutathione Transferase-Homology Domains and Aspartyl-tRNA Synthetase.
J.Mol.Biol., 2019
2OLG
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BU of 2olg by Molmil
Crystal structure of the serine protease domain of prophenoloxidase activating factor-I in a zymogen form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Pro-phenoloxidase activating enzyme-I, ...
著者Ha, N.C, Piao, S.
登録日2007-01-19
公開日2007-02-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the serine protease domain of prophenoloxidase activating factor-I
J.Biol.Chem., 282, 2007
8ERC
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BU of 8erc by Molmil
Human Membrane-bound O-acyltransferase 7
分子名称: Lysophospholipid acyltransferase 7
著者Wang, K, Liao, M, Farese, R.V, Walther, T.C.
登録日2022-10-11
公開日2023-09-27
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献The structure of phosphatidylinositol remodeling MBOAT7 reveals its catalytic mechanism and enables inhibitor identification.
Nat Commun, 14, 2023
6ICI
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BU of 6ici by Molmil
Crystal structure of human MICAL3
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, [F-actin]-monooxygenase MICAL3
著者Hwang, K.Y, Kim, J.S.
登録日2018-09-06
公開日2020-03-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and kinetic insights into flavin-containing monooxygenase and calponin-homology domains in human MICAL3.
Iucrj, 7, 2020
5H6Z
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BU of 5h6z by Molmil
Crystal structure of Set7, a novel histone methyltransferase in Schizossacharomyces pombe
分子名称: AMMONIUM ION, DI(HYDROXYETHYL)ETHER, SET domain-containing protein 7, ...
著者Mevius, D.E.H.F, Shen, Y, Morishita, M, Carrozzini, B, Caliandro, R, di Luccio, E.
登録日2016-11-15
公開日2017-11-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Set7 Is a H3K37 Methyltransferase in Schizosaccharomyces pombe and Is Required for Proper Gametogenesis.
Structure, 27, 2019
4R3Z
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BU of 4r3z by Molmil
Crystal structure of human ArgRS-GlnRS-AIMP1 complex
分子名称: Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Arginine--tRNA ligase, cytoplasmic, ...
著者Fu, Y, Kim, Y, Cho, Y.
登録日2014-08-18
公開日2014-10-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (4.033 Å)
主引用文献Structure of the ArgRS-GlnRS-AIMP1 complex and its implications for mammalian translation
Proc.Natl.Acad.Sci.USA, 111, 2014
6B0F
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BU of 6b0f by Molmil
ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH LSZ102
分子名称: Estrogen receptor, GLYCEROL, LSZ102
著者Kirby, C.A, Baird, J.
登録日2017-09-14
公開日2018-04-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer.
J. Med. Chem., 61, 2018
4K86
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BU of 4k86 by Molmil
Crystal structure of human prolyl-tRNA synthetase (apo form)
分子名称: Proline--tRNA ligase, ZINC ION
著者Hwang, K.Y, Son, J.H, Lee, E.H.
登録日2013-04-18
公開日2013-10-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone.
Acta Crystallogr.,Sect.D, 69, 2013
4K87
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BU of 4k87 by Molmil
Crystal structure of human prolyl-tRNA synthetase (substrate bound form)
分子名称: ADENOSINE, PROLINE, Proline--tRNA ligase, ...
著者Hwang, K.Y, Son, J.H, Lee, E.H.
登録日2013-04-18
公開日2013-10-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone.
Acta Crystallogr.,Sect.D, 69, 2013
2MNU
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BU of 2mnu by Molmil
Backbone and side chain 1H, 13C, and 15N Chemical Shift Assignments for EDB and specific binding aptide
分子名称: APT, EDB
著者Suh, J, Yu, T.
登録日2014-04-10
公開日2014-09-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献An Unusual Protein-Protein Interaction through Coupled Unfolding and Binding
Angew.Chem.Int.Ed.Engl., 53, 2014
4K88
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BU of 4k88 by Molmil
Crystal structure of human prolyl-tRNA synthetase (halofuginone bound form)
分子名称: 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, Proline--tRNA ligase, ZINC ION
著者Hwang, K.Y, Son, J.H, Lee, E.H.
登録日2013-04-18
公開日2013-10-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.619 Å)
主引用文献Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone.
Acta Crystallogr.,Sect.D, 69, 2013
6OWL
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BU of 6owl by Molmil
RNA oligonucleotides with 3'-arabino guanosine co-crystallized with GMP
分子名称: RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*R)-3'), RNA (5'-R(P*G)-3')
著者Szostak, J.W, Kim, S, Zhang, W.
登録日2019-05-10
公開日2020-02-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Model for the Emergence of RNA from a Prebiotically Plausible Mixture of Ribonucleotides, Arabinonucleotides, and 2'-Deoxynucleotides.
J.Am.Chem.Soc., 142, 2020
5T1F
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BU of 5t1f by Molmil
Crystal structure of Phaeospaeria nodrum fructosyl peptide oxidase mutant Asn56Ala
分子名称: ACETIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, Uncharacterized protein
著者Yoshida, H, Shimasaki, T, Kamitori, S, Sode, K.
登録日2016-08-19
公開日2017-06-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献X-ray structures of fructosyl peptide oxidases revealing residues responsible for gating oxygen access in the oxidative half reaction
Sci Rep, 7, 2017
5T1E
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BU of 5t1e by Molmil
Crystal structure of Phaeospaeria nodrum fructosyl peptide oxidase
分子名称: ACETIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, Uncharacterized protein
著者Yoshida, H, Shimasaki, T, Kamitori, S, Sode, K.
登録日2016-08-19
公開日2017-06-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献X-ray structures of fructosyl peptide oxidases revealing residues responsible for gating oxygen access in the oxidative half reaction
Sci Rep, 7, 2017
6IJQ
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BU of 6ijq by Molmil
Solution structure of BCL-XL bound to P73-TAD peptide
分子名称: Bcl-2-like protein 1,Bcl-2-like protein 1, Tumor protein p73
著者Yoon, M.-K, Ha, J.-H, Lee, M.-S, Chi, S.-W.
登録日2018-10-11
公開日2018-11-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Cytoplasmic pro-apoptotic function of the tumor suppressor p73 is mediated through a modified mode of recognition of the anti-apoptotic regulator Bcl-XL.
J. Biol. Chem., 293, 2018
8DA0
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BU of 8da0 by Molmil
Crystal structure of Mamba alpha-neurotoxin in complex with Centi-3FTX-D09 antibody
分子名称: ACETATE ION, Alpha-elapitoxin-Dpp2d, Centi-3FTX-D09 Fab heavy chain, ...
著者Pletnev, S, Verardi, R, Tully, E.S, Glanville, J, Kwong, P.D.
登録日2022-06-12
公開日2023-06-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Venom protection by antibody from a snakebite hyperimmune subject
To Be Published
8D9Y
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BU of 8d9y by Molmil
Crystal structure of Taipan alpha-neurotoxin in complex with Centi-3FTX-D09 antibody
分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Centi-3FTX-D09 Fab heavy chain, ...
著者Pletnev, S, Verardi, R, Tully, E.S, Glanville, J, Kwong, P.D.
登録日2022-06-12
公開日2023-06-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Venom protection by antibody from a snakebite hyperimmune subject
To Be Published
8DA1
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BU of 8da1 by Molmil
Crystal structure of Krait alpha-neurotoxin in complex with Centi-3FTX-D09 antibody
分子名称: Alpha-bungarotoxin, Centi-3FTX-D09 Fab heavy chain, Centi-3FTX-D09 Fab light chain
著者Pletnev, S, Verardi, R, Tully, E.S, Glanville, J, Kwong, P.D.
登録日2022-06-12
公開日2023-06-14
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Venom protection by antibody from a snakebite hyperimmune subject
To Be Published
8D9Z
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BU of 8d9z by Molmil
Crystal structure of Cobra alpha-neurotoxin in complex with Centi-3FTX-D09 antibody
分子名称: ACETATE ION, Centi-3FTX-D09 Fab heavy chain, Centi-3FTX-D09 Fab light chain, ...
著者Pletnev, S, Verardi, R, Tully, E.S, Glanville, J, Kwong, P.D.
登録日2022-06-12
公開日2023-06-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Venom protection by antibody from a snakebite hyperimmune subject
To Be Published
3II5
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BU of 3ii5 by Molmil
The Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitor
分子名称: B-Raf proto-oncogene serine/threonine-protein kinase, N-[3-(3-{4-[(dimethylamino)methyl]phenyl}pyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide, PHOSPHATE ION
著者Xu, W, Breger, D, Torres, N, Dutia, M, Powell, D, Ciszewski, G.
登録日2009-07-31
公開日2009-11-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors.
Bioorg.Med.Chem.Lett., 19, 2009
5E1T
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BU of 5e1t by Molmil
Crystal structure of TRAF1 TRAF domain
分子名称: TNF receptor-associated factor 1
著者Park, H.H, Kim, C.M.
登録日2015-09-30
公開日2016-12-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of TRAF1 TRAF domain and its implications in the TRAF1-mediated intracellular signaling pathway
Sci Rep, 6, 2016
4E37
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BU of 4e37 by Molmil
Crystal Structure of P. aeruginosa catalase, KatA tetramer
分子名称: Catalase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTOPORPHYRIN IX CONTAINING FE
著者VanderWielen, B.D, Wilson, J.J, Kovall, R.A.
登録日2012-03-09
公開日2013-03-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献KatA, the Major Catalase in Pseudomonas aeruginosa, Assists in Protecting Anaerobic Bacteria From Metabolic and Exogenous Nitric Oxide
To be Published
1DU3
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BU of 1du3 by Molmil
Crystal structure of TRAIL-SDR5
分子名称: DEATH RECEPTOR 5, TNF-RELATED APOPTOSIS INDUCING LIGAND, ZINC ION
著者Cha, S.-S, Sung, B.-J, Oh, B.-H.
登録日2000-01-14
公開日2000-09-27
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of TRAIL-DR5 complex identifies a critical role of the unique frame insertion in conferring recognition specificity
J.Biol.Chem., 275, 2000
5YC1
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BU of 5yc1 by Molmil
TRAF4_GPIb complex
分子名称: GPIb peptide, TNF receptor-associated factor 4
著者Park, H.H, Kim, C.M.
登録日2017-09-06
公開日2017-10-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.506 Å)
主引用文献Molecular basis for unique specificity of human TRAF4 for platelets GPIb beta and GPVI
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2HWC
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BU of 2hwc by Molmil
A COMPARISON OF THE ANTI-RHINOVIRAL DRUG BINDING POCKET IN HRV14 AND HRV1A
分子名称: 5-(5-(2,6-DICHLORO-4-(4,5-DIHYDRO-2-OXAZOLY)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ...
著者Kim, K.H, Rossmann, M.G.
登録日1994-01-25
公開日1994-11-01
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A comparison of the anti-rhinoviral drug binding pocket in HRV14 and HRV1A.
J.Mol.Biol., 230, 1993

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