4M0Y
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4M13
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4M12
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4M0Z
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4M14
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4M15
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5LDF
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5Y27
| Crystal structure of Se-Met Dpb4-Dpb3 | 分子名称: | DNA polymerase epsilon subunit D, GLYCEROL, Putative transcription factor C16C4.22 | 著者 | Li, Y, Gao, F, Su, M, Zhang, F.B, Chen, Y.H. | 登録日 | 2017-07-24 | 公開日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Coordinated regulation of heterochromatin inheritance by Dpb3-Dpb4 complex. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6UDN
| Crystal Structure of a Self-Assembling DNA Scaffold Containing TA Sticky Ends and Rhombohedral Symmetry | 分子名称: | ARSENIC, DNA (5'-D(*TP*AP*CP*TP*GP*AP*CP*TP*CP*AP*TP*GP*CP*TP*CP*AP*TP*CP*TP*GP*A)-3'), DNA (5'-D(*TP*AP*TP*CP*AP*GP*AP*TP*G)-3'), ... | 著者 | Simmons, C.R, MacCulloch, T, Stephanopoulos, N, Yan, H. | 登録日 | 2019-09-19 | 公開日 | 2020-09-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | 主引用文献 | A Self-Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High-Resolution Structural Detail. Angew.Chem.Int.Ed.Engl., 59, 2020
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6U40
| Crystal Structure of a Self-Assembling DNA Crystal Scaffold with Rhombohedral Symmetry | 分子名称: | CACODYLATE ION, DNA (5'-D(*CP*AP*CP*TP*GP*AP*CP*TP*CP*AP*TP*GP*CP*TP*CP*AP*TP*CP*TP*GP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*AP*GP*AP*TP*G)-3'), ... | 著者 | Simmons, C.R, MacCulloch, T, Stephanopoulos, N, Yan, H. | 登録日 | 2019-08-22 | 公開日 | 2020-08-26 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.702 Å) | 主引用文献 | A Self-Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High-Resolution Structural Detail. Angew.Chem.Int.Ed.Engl., 59, 2020
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6UEF
| Crystal Structure of a Self-Assembling DNA Scaffold Containing Sequence Modifications to Attempt to Disrupt Crystal Contacts in a Rhombohedral Lattice. | 分子名称: | DNA (5'-D(*CP*AP*AP*TP*GP*AP*CP*TP*CP*AP*TP*GP*CP*TP*CP*AP*TP*CP*GP*GP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*GP*AP*TP*G)-3'), DNA (5'-D(P*AP*GP*CP*AP*TP*GP*A)-3'), ... | 著者 | Simmons, C.R, MacCulloch, T, Stephanopoulos, N, Yan, H. | 登録日 | 2019-09-20 | 公開日 | 2020-09-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | A Self-Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High-Resolution Structural Detail. Angew.Chem.Int.Ed.Engl., 59, 2020
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5Y26
| Crystal structure of native Dpb4-Dpb3 | 分子名称: | DNA polymerase epsilon subunit D, GLYCEROL, Putative transcription factor C16C4.22 | 著者 | Chen, Y.H, Li, Y, Gao, F. | 登録日 | 2017-07-24 | 公開日 | 2018-01-24 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.003 Å) | 主引用文献 | Coordinated regulation of heterochromatin inheritance by Dpb3-Dpb4 complex. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6V6R
| Crystal Structure of a Bromine Derivatized Self-Assembling DNA Crystal Scaffold with Rhombohedral Symmetry. | 分子名称: | CACODYLATE ION, DNA (5'-D(*CP*AP*CP*TP*GP*AP*CP*TP*CP*AP*TP*GP*CP*TP*CP*AP*TP*CP*TP*GP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*AP*GP*AP*TP*G)-3'), ... | 著者 | Simmons, C.R, MacCulloch, T, Stephanopoulos, N, Yan, H. | 登録日 | 2019-12-05 | 公開日 | 2020-12-09 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A Self-Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High-Resolution Structural Detail. Angew.Chem.Int.Ed.Engl., 59, 2020
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7YSF
| Crystal structure of ZNF524 ZF1-4 in complex with telomeric DNA | 分子名称: | D-MALATE, DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*CP*CP*C)-3'), ... | 著者 | Li, F.D, Xu, Z.Y. | 登録日 | 2022-08-12 | 公開日 | 2023-08-16 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | ZNF524 directly interacts with telomeric DNA and supports telomere integrity. Nat Commun, 14, 2023
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3H0S
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3H0Q
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3H0J
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7QHD
| Human Butyrylcholinesterase in complex with (S)-1-(4-((2-(1H-indol-3-yl)ethyl)carbamoyl)benzyl)-N-(3-((1,2,3,4-tetrahydroacridin-9-yl)amino)propyl)piperidine-3-carboxamide | 分子名称: | (3~{S})-1-[[4-[2-(1~{H}-indol-3-yl)ethylcarbamoyl]phenyl]methyl]-~{N}-[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]piperidine-3-carboxamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Brazzolotto, X, Jing, L, Zhan, P, Liu, X, Nachon, F. | 登録日 | 2021-12-12 | 公開日 | 2022-12-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Rapid discovery and crystallography study of highly potent and selective butylcholinesterase inhibitors based on oxime-containing libraries and conformational restriction strategies. Bioorg.Chem., 134, 2023
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7QHE
| Human Butyrylcholinesterase in complex with (S)-1-(4-((naphthalen-1-yl)carbamoyl)benzyl)-N-(3-((1,2,3,4-tetrahydroacridin-9-yl)amino)propyl)piperidine-3-carboxamide | 分子名称: | (3~{S})-1-[[4-(naphthalen-1-ylcarbamoyl)phenyl]methyl]-~{N}-[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]piperidine-3-carboxamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Brazzolotto, X, Jing, L, Zhan, P, Liu, X, Nachon, F. | 登録日 | 2021-12-12 | 公開日 | 2022-12-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Rapid discovery and crystallography study of highly potent and selective butylcholinesterase inhibitors based on oxime-containing libraries and conformational restriction strategies. Bioorg.Chem., 134, 2023
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7RN0
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2RVH
| NMR structure of eIF1 | 分子名称: | Eukaryotic translation initiation factor eIF-1 | 著者 | Nagata, T, Obayashi, E, Asano, K. | 登録日 | 2015-10-16 | 公開日 | 2016-10-26 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5 Cell Rep, 18, 2017
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7U23
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7PJR
| Notum_ARUK3000438 | 分子名称: | 1-[4-chloranyl-3-(trifluoromethyl)phenyl]-1,2,3-triazole, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | 著者 | Vecchia, L, Zhao, Y, Fish, P, Jones, E.Y. | 登録日 | 2021-08-24 | 公開日 | 2022-09-07 | 最終更新日 | 2023-03-22 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit. J.Med.Chem., 65, 2022
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7PK3
| Notum_ARUK3001185 | 分子名称: | 1-[2,4-bis(chloranyl)-3-(trifluoromethyl)phenyl]-1,2,3-triazole, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | 著者 | Vecchia, L, Hillier, J, Zhao, Y, Fish, P, Jones, E.Y. | 登録日 | 2021-08-25 | 公開日 | 2022-09-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit. J.Med.Chem., 65, 2022
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7PKV
| Notum_Inhibitor ARUK3000223 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, Palmitoleoyl-protein carboxylesterase NOTUM, ... | 著者 | Ruza, R, Zhao, Y, Fish, P, Jones, E.Y. | 登録日 | 2021-08-26 | 公開日 | 2022-09-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit. J.Med.Chem., 65, 2022
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