8CE1
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![BU of 8ce1 by Molmil](/molmil-images/mine/8ce1) | Cytochrome c maturation complex CcmABCD | 分子名称: | Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, Heme exporter protein C, ... | 著者 | Ilcu, L, Zhang, L, Einsle, O. | 登録日 | 2023-02-01 | 公開日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Architecture of the Heme-translocating CcmABCD/E complex required for Cytochrome c maturation. Nat Commun, 14, 2023
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6ORI
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![BU of 6ori by Molmil](/molmil-images/mine/6ori) | Enterococcal surface protein, partial N-terminal region | 分子名称: | CALCIUM ION, EF0056 | 著者 | Spiegelman, L, Zhang, L, Tezcan, A, Ghosh, P. | 登録日 | 2019-04-30 | 公開日 | 2020-05-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Enterococcal surface protein, partial N-terminal region (CASP target) To Be Published
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7NEV
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![BU of 7nev by Molmil](/molmil-images/mine/7nev) | Structure of the hemiacetal complex between the SARS-CoV-2 Main Protease and Leupeptin | 分子名称: | 3C-like proteinase, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Guenther, S, Reinke, P.Y.A, Oberthuer, D, Yefanov, O, Gelisio, L, Ginn, H.M, Lieske, J, Domaracky, M, Brehm, W, Rahmani Mashhour, A, White, T.A, Knoska, J, Pena Esperanza, G, Koua, F, Tolstikova, A, Groessler, M, Fischer, P, Hennicke, V, Fleckenstein, H, Trost, F, Galchenkova, M, Gevorkov, Y, Li, C, Awel, S, Xavier, P.L, Ullah, N, Andaleeb, H, Falke, S, Alves Franca, B, Schwinzer, M, Brognaro, H, Werner, N, Perbandt, M, Tidow, H, Seychell, B, Beck, T, Meier, S, Zaitsev-Doyle, J.J, Rogers, C, Gieseler, H, Melo, D, Monteiro, D.C.F, Dunkel, I, Lane, T.J, Peck, A, Saouane, S, Hakanpaeae, J, Meyer, J, Noei, H, Gribbon, P, Ellinger, B, Kuzikov, M, Wolf, M, Zhang, L, Ehrt, C, Pletzer-Zelgert, J, Wollenhaupt, J, Feiler, C, Weiss, M, Schluenzen, F, Schulz, E.C, Mehrabi, P, Norton-Baker, B, Schmidt, C, Lorenzen, K, Schubert, R, Sun, X, Han, H, Chari, A, Fernandez Garcia, Y, Turk, D, Hilgenfeld, R, Rarey, M, Zaliani, A, Chapman, H.N, Pearson, A, Betzel, C, Meents, A. | 登録日 | 2021-02-05 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease. Science, 372, 2021
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8CE8
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![BU of 8ce8 by Molmil](/molmil-images/mine/8ce8) | Cytochrome c maturation complex CcmABCDE | 分子名称: | Cytochrome c biogenesis ATP-binding export protein CcmA, Cytochrome c-type biogenesis protein CcmE, Heme exporter protein B, ... | 著者 | Ilcu, L, Zhang, L, Einsle, O. | 登録日 | 2023-02-01 | 公開日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (3.81 Å) | 主引用文献 | Architecture of the Heme-translocating CcmABCD/E complex required for Cytochrome c maturation. Nat Commun, 14, 2023
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6M54
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![BU of 6m54 by Molmil](/molmil-images/mine/6m54) | Human apo ferritin frozen on TEM grid with Amorphous nickel titanium alloy supporting film | 分子名称: | FE (II) ION, Ferritin heavy chain | 著者 | Huang, X, Zhang, L, Wen, Z, Chen, H, Li, S, Ji, G, Yin, C, Sun, F. | 登録日 | 2020-03-09 | 公開日 | 2020-05-13 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Amorphous nickel titanium alloy film: A new choice for cryo electron microscopy sample preparation. Prog.Biophys.Mol.Biol., 156, 2020
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6M52
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![BU of 6m52 by Molmil](/molmil-images/mine/6m52) | Human apo ferritin frozen on TEM grid with amorphous carbon supporting film | 分子名称: | FE (II) ION, Ferritin heavy chain | 著者 | Huang, X, Zhang, L, Wen, Z, Chen, H, Li, S, Ji, G, Yin, C, Sun, F. | 登録日 | 2020-03-09 | 公開日 | 2020-05-13 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Amorphous nickel titanium alloy film: A new choice for cryo electron microscopy sample preparation. Prog.Biophys.Mol.Biol., 156, 2020
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8A4Q
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![BU of 8a4q by Molmil](/molmil-images/mine/8a4q) | crystal structures of diastereomer (R,S,S)-13b (13b-H) in complex with the SARS-CoV-2 Mpro. | 分子名称: | 3C-like proteinase nsp5, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Ibrahim, M, Hilgenfeld, R, Zhang, L. | 登録日 | 2022-06-13 | 公開日 | 2022-10-12 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Diastereomeric Resolution Yields Highly Potent Inhibitor of SARS-CoV-2 Main Protease. J.Med.Chem., 65, 2022
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8CE5
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![BU of 8ce5 by Molmil](/molmil-images/mine/8ce5) | Cytochrome c maturation complex CcmABCD, E154Q, ATP-bound | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ... | 著者 | Ilcu, L, Zhang, L, Einsle, O. | 登録日 | 2023-02-01 | 公開日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | 主引用文献 | Architecture of the Heme-translocating CcmABCD/E complex required for Cytochrome c maturation. Nat Commun, 14, 2023
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6N7X
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![BU of 6n7x by Molmil](/molmil-images/mine/6n7x) | S. cerevisiae U1 snRNP | 分子名称: | 56 kDa U1 small nuclear ribonucleoprotein component, Pre-mRNA-processing factor 39, Protein NAM8, ... | 著者 | Li, X, Liu, S, Jiang, J, Zhang, L, Espinosa, S, Hill, R.C, Hansen, K.C, Zhou, Z.H, Zhao, R. | 登録日 | 2018-11-28 | 公開日 | 2019-07-24 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing. Nat Commun, 8, 2017
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6N46
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4JNM
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![BU of 4jnm by Molmil](/molmil-images/mine/4jnm) | Discovery of Potent and Efficacious Urea-containing Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors with Reduced CYP2C9 Inhibition Properties | 分子名称: | 1,2-ETHANEDIOL, 1-[(6-aminopyridin-3-yl)methyl]-3-[4-(phenylsulfonyl)phenyl]urea, Nicotinamide phosphoribosyltransferase, ... | 著者 | Gunzner-Toste, J, Zhao, G, Bauer, P, Baumeister, T, Buckmelter, A.J, Caligiuri, M, Clodfelter, K.H, Fu, B, Han, B, Ho, Y, Kley, N, Liederer, B, Lin, J, Mukadam, S, O'Brien, T, Reynolds, D.J, Sharma, G, Skelton, N, Smith, C.C, Oh, A, Wang, W, Wang, Z, Xiao, Y, Yuen, P, Zak, M, Zhang, L, Zheng, X, Bair, K.W, Dragovich, P.S. | 登録日 | 2013-03-15 | 公開日 | 2013-05-29 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties. Bioorg.Med.Chem.Lett., 23, 2013
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7OSH
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![BU of 7osh by Molmil](/molmil-images/mine/7osh) | ABC Transporter complex NosDFYL, R-domain 2 | 分子名称: | COPPER (II) ION, Copper-binding lipoprotein NosL, MAGNESIUM ION, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Du, J, Einsle, O. | 登録日 | 2021-06-08 | 公開日 | 2022-06-22 | 最終更新日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7OSJ
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![BU of 7osj by Molmil](/molmil-images/mine/7osj) | ABC Transporter complex NosDFYL, membrane anchor | 分子名称: | COPPER (II) ION, Copper-binding lipoprotein NosL, MAGNESIUM ION, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Du, J, Einsle, O. | 登録日 | 2021-06-08 | 公開日 | 2022-06-22 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7OSG
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![BU of 7osg by Molmil](/molmil-images/mine/7osg) | ABC Transporter complex NosDFYL, consensus refinement | 分子名称: | COPPER (II) ION, Copper-binding lipoprotein NosL, MAGNESIUM ION, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Du, J, Einsle, O. | 登録日 | 2021-06-08 | 公開日 | 2022-06-22 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7OSI
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![BU of 7osi by Molmil](/molmil-images/mine/7osi) | ABC Transporter complex NosDFYL, R-domain 3 | 分子名称: | COPPER (II) ION, Copper-binding lipoprotein NosL, MAGNESIUM ION, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Du, J, Einsle, O. | 登録日 | 2021-06-08 | 公開日 | 2022-06-22 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7OSF
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![BU of 7osf by Molmil](/molmil-images/mine/7osf) | ABC Transporter complex NosDFYL, R-domain 1 | 分子名称: | COPPER (II) ION, Copper-binding lipoprotein NosL, MAGNESIUM ION, ... | 著者 | Mueller, C, Zhang, L, Lu, W, Du, J, Einsle, O. | 登録日 | 2021-06-08 | 公開日 | 2022-06-22 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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6A67
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![BU of 6a67 by Molmil](/molmil-images/mine/6a67) | Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody FLD21.140 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FLD21.140 Heavy Chain, FLD21.140 Light Chain, ... | 著者 | Wang, P, Zuo, Y, Sun, J, Zhang, L, Wang, X. | 登録日 | 2018-06-26 | 公開日 | 2018-08-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Complementary recognition of the receptor-binding site of highly pathogenic H5N1 influenza viruses by two human neutralizing antibodies. J. Biol. Chem., 293, 2018
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8CWR
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8CWT
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7QBA
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![BU of 7qba by Molmil](/molmil-images/mine/7qba) | CryoEM structure of the ABC transporter NosDFY complexed with nitrous oxide reductase NosZ | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ... | 著者 | Zipfel, S, Mueller, C, Topitsch, A, Lutz, M, Zhang, L, Einsle, O. | 登録日 | 2021-11-18 | 公開日 | 2022-08-03 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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4KQW
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![BU of 4kqw by Molmil](/molmil-images/mine/4kqw) | The structure of the Slackia exigua KARI in complex with NADP | 分子名称: | Ketol-acid reductoisomerase, L(+)-TARTARIC ACID, MAGNESIUM ION, ... | 著者 | Brinkmann-Chen, S, Flock, T, Cahn, J.K.B, Snow, C.D, Brustad, E.M, Mcintosh, J.A, Meinhold, P, Zhang, L, Arnold, F.H. | 登録日 | 2013-05-15 | 公開日 | 2013-06-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH. Proc.Natl.Acad.Sci.USA, 110, 2013
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4KT8
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![BU of 4kt8 by Molmil](/molmil-images/mine/4kt8) | The complex structure of Rv3378c-Y51FY90F with substrate, TPP | 分子名称: | (2E)-3-methyl-5-[(1R,2S,8aS)-1,2,5,5-tetramethyl-1,2,3,5,6,7,8,8a-octahydronaphthalen-1-yl]pent-2-en-1-yl trihydrogen diphosphate, Diterpene synthase, PHOSPHATE ION | 著者 | Chan, H.C, Feng, X, Ko, T.P, Huang, C.H, Hu, Y, Zheng, Y, Bogue, S, Nakano, C, Hoshino, T, Zhang, L, Lv, P, Liu, W, Crick, D.C, Liang, P.H, Wang, A.H, Oldfield, E, Guo, R.T. | 登録日 | 2013-05-20 | 公開日 | 2014-02-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis. J.Am.Chem.Soc., 136, 2014
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4KQX
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![BU of 4kqx by Molmil](/molmil-images/mine/4kqx) | Mutant Slackia exigua KARI DDV in complex with NAD and an inhibitor | 分子名称: | HISTIDINE, Ketol-acid reductoisomerase, MAGNESIUM ION, ... | 著者 | Brinkmann-Chen, S, Flock, T, Cahn, J.K.B, Snow, C.D, Brustad, E.M, Mcintosh, J.A, Meinhold, P, Zhang, L, Arnold, F.H. | 登録日 | 2013-05-15 | 公開日 | 2013-06-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH. Proc.Natl.Acad.Sci.USA, 110, 2013
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4NPM
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4NPL
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