4N5Q
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![BU of 4n5q by Molmil](/molmil-images/mine/4n5q) | Crystal structure of the N-terminal ankyrin repeat domain of TRPV3 | 分子名称: | Transient receptor potential cation channel subfamily V member 3 | 著者 | Shi, D.J, Ye, S, Cao, X, Wang, K.W, Zhang, R. | 登録日 | 2013-10-10 | 公開日 | 2014-01-29 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.946 Å) | 主引用文献 | Crystal structure of the N-terminal ankyrin repeat domain of TRPV3 reveals unique conformation of finger 3 loop critical for channel function Protein Cell, 4, 2013
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8GZF
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![BU of 8gzf by Molmil](/molmil-images/mine/8gzf) | Crystal Structure of METTL9-SAH | 分子名称: | Protein-L-histidine N-pros-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Zhao, W.T, Li, H.T. | 登録日 | 2022-09-26 | 公開日 | 2023-05-31 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular basis for protein histidine N1-specific methylation of the "His-x-His" motifs by METTL9. Cell Insight, 2, 2023
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8GZE
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![BU of 8gze by Molmil](/molmil-images/mine/8gze) | |
7WSB
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![BU of 7wsb by Molmil](/molmil-images/mine/7wsb) | The ternary complex structure of FtmOx1 with a-ketoglutarate and 13-oxo-fumitremorgin B | 分子名称: | 13-Oxofumitremorgin B, 2-OXOGLUTARIC ACID, COBALT (II) ION, ... | 著者 | Wang, J, Wang, X.Y, Wang, Y.Y, Yan, W.P. | 登録日 | 2022-01-28 | 公開日 | 2022-07-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | 主引用文献 | Dissecting the Mechanism of the Nonheme Iron Endoperoxidase FtmOx1 Using Substrate Analogues. Jacs Au, 2, 2022
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6K7P
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![BU of 6k7p by Molmil](/molmil-images/mine/6k7p) | Crystal structure of human AFF4-THD domain | 分子名称: | AF4/FMR2 family member 4 | 著者 | Tang, D, Xue, Y, Li, S, Cheng, W, Duan, J, Wang, J, Qi, S. | 登録日 | 2019-06-08 | 公開日 | 2020-03-11 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and functional insight into the effect of AFF4 dimerization on activation of HIV-1 proviral transcription. Cell Discov, 6, 2020
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2L01
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![BU of 2l01 by Molmil](/molmil-images/mine/2l01) | Solution NMR Structure of protein BVU3908 from Bacteroides vulgatus, Northeast Structural Genomics Consortium Target BvR153 | 分子名称: | Uncharacterized protein | 著者 | Eletsky, A, Lee, C, Wang, K, Ciccosanti, T.B, Hamilton, R, Acton, J.B, Xiao, G.B, Everett, J.K, Prestegard, J.H, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2010-06-29 | 公開日 | 2010-08-25 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of protein BVU3908 from Bacteroides vulgatus To be Published
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5XVA
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![BU of 5xva by Molmil](/molmil-images/mine/5xva) | Crystal Structure of PAK4 in complex with inhibitor CZH216 | 分子名称: | ETHANOL, Serine/threonine-protein kinase PAK 4, [6-chloranyl-4-[(5-methyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl]-[(3R)-3-methylpiperazin-1-yl]methanone | 著者 | Zhao, F, Li, H. | 登録日 | 2017-06-27 | 公開日 | 2018-02-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.847 Å) | 主引用文献 | Structure-Based Design of 6-Chloro-4-aminoquinazoline-2-carboxamide Derivatives as Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors. J. Med. Chem., 61, 2018
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5XVG
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![BU of 5xvg by Molmil](/molmil-images/mine/5xvg) | Crystal Structure of PAK4 in complex with inhibitor CZH226 | 分子名称: | 1,2-ETHANEDIOL, ETHANOL, Serine/threonine-protein kinase PAK 4, ... | 著者 | Zhao, F, Li, H. | 登録日 | 2017-06-27 | 公開日 | 2018-02-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure-Based Design of 6-Chloro-4-aminoquinazoline-2-carboxamide Derivatives as Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors. J. Med. Chem., 61, 2018
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5DT1
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![BU of 5dt1 by Molmil](/molmil-images/mine/5dt1) | |
8TGN
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![BU of 8tgn by Molmil](/molmil-images/mine/8tgn) | VMAT1 dimer with serotonin and reserpine | 分子名称: | Chromaffin granule amine transporter, SEROTONIN, reserpine | 著者 | Ye, J, Liu, B, Li, W. | 登録日 | 2023-07-12 | 公開日 | 2024-03-20 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGL
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![BU of 8tgl by Molmil](/molmil-images/mine/8tgl) | |
8TGI
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![BU of 8tgi by Molmil](/molmil-images/mine/8tgi) | VMAT1 dimer with dopamine and reserpine | 分子名称: | Chromaffin granule amine transporter, L-DOPAMINE, reserpine | 著者 | Ye, J, Liu, B, Li, W. | 登録日 | 2023-07-12 | 公開日 | 2024-03-20 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGM
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![BU of 8tgm by Molmil](/molmil-images/mine/8tgm) | VMAT1 dimer with reserpine | 分子名称: | VMAT1 dimer with reserpine, reserpine | 著者 | Ye, J, Liu, B, Li, W. | 登録日 | 2023-07-12 | 公開日 | 2024-03-20 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGG
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![BU of 8tgg by Molmil](/molmil-images/mine/8tgg) | VMAT1 dimer with MPP+ and reserpine | 分子名称: | 1-methyl-4-phenylpyridin-1-ium, Chromaffin granule amine transporter, reserpine | 著者 | Ye, J, Liu, B, Li, W. | 登録日 | 2023-07-12 | 公開日 | 2024-03-20 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGH
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![BU of 8tgh by Molmil](/molmil-images/mine/8tgh) | VMAT1 dimer with amphetamine and reserpine | 分子名称: | (2S)-1-phenylpropan-2-amine, Chromaffin granule amine transporter, reserpine | 著者 | Ye, J, Liu, B, Li, W. | 登録日 | 2023-07-12 | 公開日 | 2024-03-20 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGJ
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![BU of 8tgj by Molmil](/molmil-images/mine/8tgj) | |
8TGK
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![BU of 8tgk by Molmil](/molmil-images/mine/8tgk) | VMAT1 dimer with histamine and reserpine | 分子名称: | Chromaffin granule amine transporter, HISTAMINE, reserpine | 著者 | Ye, J, Liu, B, Li, W. | 登録日 | 2023-07-12 | 公開日 | 2024-03-20 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8JLP
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![BU of 8jlp by Molmil](/molmil-images/mine/8jlp) | Ralmitaront(RO-6889450)-bound hTAAR1-Gs protein complex | 分子名称: | 5-ethyl-4-methyl-~{N}-[4-[(2~{S})-morpholin-2-yl]phenyl]-1~{H}-pyrazole-3-carboxamide, Gs, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Xu, Z, Guo, L.L, Zhao, C, Shen, S.Y, Sun, J.P, Shao, Z.H. | 登録日 | 2023-06-02 | 公開日 | 2023-11-15 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Ligand recognition and G-protein coupling of trace amine receptor TAAR1. Nature, 624, 2023
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8JLK
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![BU of 8jlk by Molmil](/molmil-images/mine/8jlk) | Ulotaront(SEP-363856)-bound mTAAR1-Gs protein complex | 分子名称: | 1-[(7~{S})-5,7-dihydro-4~{H}-thieno[2,3-c]pyran-7-yl]-~{N}-methyl-methanamine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Xu, Z, Guo, L.L, Zhao, C, Shen, S.Y, Sun, J.P, Shao, Z.H. | 登録日 | 2023-06-02 | 公開日 | 2023-11-15 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | 主引用文献 | Ligand recognition and G-protein coupling of trace amine receptor TAAR1. Nature, 624, 2023
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8JLQ
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![BU of 8jlq by Molmil](/molmil-images/mine/8jlq) | Fenoldopam-bound hTAAR1-Gs protein complex | 分子名称: | (1R)-6-chloranyl-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Xu, Z, Guo, L.L, Zhao, C, Shen, S.Y, Sun, J.P, Shao, Z.H. | 登録日 | 2023-06-02 | 公開日 | 2023-11-15 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | Ligand recognition and G-protein coupling of trace amine receptor TAAR1. Nature, 624, 2023
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8JLN
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![BU of 8jln by Molmil](/molmil-images/mine/8jln) | T1AM-bound hTAAR1-Gs protein complex | 分子名称: | 4-[4-(2-azanylethyl)-2-iodanyl-phenoxy]phenol, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Xu, Z, Guo, L.L, Zhao, C, Shen, S.Y, Sun, J.P, Shao, Z.H. | 登録日 | 2023-06-02 | 公開日 | 2023-11-15 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | 主引用文献 | Ligand recognition and G-protein coupling of trace amine receptor TAAR1. Nature, 624, 2023
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8JLO
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![BU of 8jlo by Molmil](/molmil-images/mine/8jlo) | Ulotaront(SEP-363856)-bound hTAAR1-Gs protein complex | 分子名称: | 1-[(7~{S})-5,7-dihydro-4~{H}-thieno[2,3-c]pyran-7-yl]-~{N}-methyl-methanamine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Xu, Z, Guo, L.L, Zhao, C, Shen, S.Y, Sun, J.P, Shao, Z.H. | 登録日 | 2023-06-02 | 公開日 | 2023-11-15 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | Ligand recognition and G-protein coupling of trace amine receptor TAAR1. Nature, 624, 2023
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8JLJ
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![BU of 8jlj by Molmil](/molmil-images/mine/8jlj) | T1AM-bound mTAAR1-Gs protein complex | 分子名称: | 4-[4-(2-azanylethyl)-2-iodanyl-phenoxy]phenol, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Xu, Z, Guo, L.L, Zhao, C, Shen, S.Y, Sun, J.P, Shao, Z.H. | 登録日 | 2023-06-02 | 公開日 | 2023-11-15 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Ligand recognition and G-protein coupling of trace amine receptor TAAR1. Nature, 624, 2023
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8JLR
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![BU of 8jlr by Molmil](/molmil-images/mine/8jlr) | A77636-bound hTAAR1-Gs protein complex | 分子名称: | (1~{S},3~{R})-3-(1-adamantyl)-1-(aminomethyl)-3,4-dihydro-1~{H}-isochromene-5,6-diol, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Xu, Z, Guo, L.L, Zhao, C, Shen, S.Y, Sun, J.P, Shao, Z.H. | 登録日 | 2023-06-02 | 公開日 | 2023-11-15 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Ligand recognition and G-protein coupling of trace amine receptor TAAR1. Nature, 624, 2023
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8JSO
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![BU of 8jso by Molmil](/molmil-images/mine/8jso) | AMPH-bound hTAAR1-Gs protein complex | 分子名称: | (2S)-1-phenylpropan-2-amine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Xu, Z, Guo, L.L, Zhao, C, Shen, S.Y, Sun, J.P, Shao, Z.H. | 登録日 | 2023-06-20 | 公開日 | 2023-11-15 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Ligand recognition and G-protein coupling of trace amine receptor TAAR1. Nature, 624, 2023
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