8TMZ
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8TMY
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5IFA
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8V06
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8V08
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8V05
| Crystal structure of mouse PLD3 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ... | 著者 | Yuan, M, Zhu, X, Wilson, I.A. | 登録日 | 2023-11-17 | 公開日 | 2024-03-13 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4. Structure, 32, 2024
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8V07
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5JS9
| Uncleaved prefusion optimized gp140 trimer with an engineered 8-residue HR1 turn bound to broadly neutralizing antibodies 8ANC195 and PGT128 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kong, L, Wilson, I.A. | 登録日 | 2016-05-07 | 公開日 | 2016-07-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (6.918 Å) | 主引用文献 | Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability. Nat Commun, 7, 2016
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5IJV
| Crystal structure of bovine Fab E03 | 分子名称: | bovine Fab E03 heavy chain, bovine Fab E03 light chain | 著者 | Stanfield, R.L, Wilson, I.A. | 登録日 | 2016-03-02 | 公開日 | 2016-10-05 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies. Sci Immunol, 1, 2016
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2IGF
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5JOP
| Crystal structure of anti-glycan antibody Fab14.22 in complex with Streptococcus pneumoniae serotype 14 tetrasaccharide at 1.75 A | 分子名称: | Fab 14.22 light chain, Fab14.22 heavy chain, GLYCEROL, ... | 著者 | Sarkar, A, Irimia, A, Teyton, L, Wilson, I.A. | 登録日 | 2016-05-02 | 公開日 | 2017-03-22 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | T cells control the generation of nanomolar-affinity anti-glycan antibodies. J. Clin. Invest., 127, 2017
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8TXT
| Crystal structure of 05.GC.w13.02 Fab in complex with H5 HA from A/Viet Nam/1203/2004(H5N1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GC_W13B_B, ... | 著者 | Lin, T.H, Moore, N, Wilson, I.A. | 登録日 | 2023-08-24 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | 主引用文献 | Maturation of germinal center B cells after influenza virus vaccination in humans. J.Exp.Med., 221, 2024
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8U03
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5JSA
| Uncleaved prefusion optimized gp140 trimer with an engineered 10-residue HR1 turn bound to broadly neutralizing antibodies 8ANC195 and PGT128 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kong, L, Wilson, I.A. | 登録日 | 2016-05-07 | 公開日 | 2016-07-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (6.308 Å) | 主引用文献 | Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability. Nat Commun, 7, 2016
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8SD4
| Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule fusion inhibitor compound 7 | 分子名称: | (S~1~S)-N-{3,5-dichloro-4-[(2S)-2-phenylmorpholine-4-carbonyl]phenyl}-3-[(dimethylamino)methyl]azetidine-1-sulfonimidoyl fluoride, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... | 著者 | Kadam, R.U, Zhu, X, Wilson, I.A. | 登録日 | 2023-04-06 | 公開日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proc.Natl.Acad.Sci.USA, 121, 2024
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8SD2
| Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule fusion inhibitor compound 4 | 分子名称: | (S~6~S)-N-{3-chloro-4-[(2S)-2-phenylmorpholine-4-carbonyl]phenyl}-5,7-dihydro-6H-pyrrolo[3,4-b]pyridine-6-sulfonimidoyl fluoride, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kadam, R.U, Zhu, X.Y, Wilson, I.A. | 登録日 | 2023-04-06 | 公開日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proc.Natl.Acad.Sci.USA, 121, 2024
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8TY7
| Crystal structure of 05.GC.w2.3C10 Fab in complex with H1 HA from A/California/04/2009(H1N1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GC_w2_3C10, heavy chain, ... | 著者 | Lin, T.H, Moore, N, Wilson, I.A. | 登録日 | 2023-08-24 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | 主引用文献 | Maturation of germinal center B cells after influenza virus vaccination in humans. J.Exp.Med., 221, 2024
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8U44
| CryoEM structure of A/Solomon Islands/3/2006 H1 HA in complex with 05.GC.w2.3C10-H1_SI06 | 分子名称: | 05.GC.w2.3C10-H1_SI06 Heavy chain, 05.GC.w2.3C10-H1_SI06 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Moore, N, Han, J, Ward, A.B, Wilson, I.A. | 登録日 | 2023-09-08 | 公開日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | 主引用文献 | Persistence of germinal center B cell responses after influenza virus vaccination in humans To Be Published
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8TZN
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8TXP
| Crystal structure of 05.GC.w13.01 Fab in complex with H1 HA from A/California/04/2009(H1N1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GC_w13_A, Fab heavy chain, ... | 著者 | Lin, T.H, Moore, N, Wilson, I.A. | 登録日 | 2023-08-24 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Maturation of germinal center B cells after influenza virus vaccination in humans. J.Exp.Med., 221, 2024
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8TZW
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8U08
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8TXM
| Crystal structure of 05.GC.w13.02 Fab in complex with H1 HA from A/California/04/2009(H1N1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GC_w13_B, ... | 著者 | Lin, T.H, Moore, N, Wilson, I.A. | 登録日 | 2023-08-23 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Maturation of germinal center B cells after influenza virus vaccination in humans. J.Exp.Med., 221, 2024
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8VQQ
| Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule 6S | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... | 著者 | Lin, T.H, Zhu, Y, Wilson, I.A. | 登録日 | 2024-01-19 | 公開日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proc.Natl.Acad.Sci.USA, 121, 2024
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8VQM
| Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule 6R prime | 分子名称: | (S~1~S,3R)-N-{3,5-dichloro-4-[(2S)-2-phenylmorpholine-4-carbonyl]phenyl}-3-(dimethylamino)pyrrolidine-1-sulfonimidoyl fluoride, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Lin, T.H, Zhu, Y, Wilson, I.A. | 登録日 | 2024-01-18 | 公開日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proc.Natl.Acad.Sci.USA, 121, 2024
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