4M8N
| Crystal Structure of PlexinC1/Rap1B Complex | 分子名称: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Pascoe, H.G, Wang, Y, Brautigam, C.A, He, H, Zhang, X. | 登録日 | 2013-08-13 | 公開日 | 2013-10-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.294 Å) | 主引用文献 | Structural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexin. Elife, 2, 2013
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4P5M
| Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergic Hypersensitivity and Autoimmunity | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wang, Y, Dai, S, Kappler, J. | 登録日 | 2014-03-18 | 公開日 | 2014-08-27 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell, 158, 2014
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6ISO
| Human SIRT3 Recognizing H3K4cr | 分子名称: | (2E)-BUT-2-ENAL, ARG-THR-LYS-GLN-THR-ALA-ARG, GLYCEROL, ... | 著者 | Wang, Y, Hao, Q. | 登録日 | 2018-11-17 | 公開日 | 2019-01-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Identification of 'erasers' for lysine crotonylated histone marks using a chemical proteomics approach. Elife, 3, 2014
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4PGF
| The structure of mono-acetylated SAHH | 分子名称: | ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Kavran, J.M, Wang, Y, Cole, P.A, Leahy, D.J. | 登録日 | 2014-05-01 | 公開日 | 2014-10-01 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Regulation of s-adenosylhomocysteine hydrolase by lysine acetylation. J.Biol.Chem., 289, 2014
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4PFC
| Crystal structure of insulin degrading enzyme complexed with inhibitor | 分子名称: | Insulin-degrading enzyme, ZINC ION, methyl [(2S)-2-(5-{5-[4-({(2S)-2-[(3S)-3-amino-2-oxopiperidin-1-yl]-2-cyclohexylacetyl}amino)phenyl]pentyl}-2-fluorophenyl)-3-(quinolin-3-yl)propyl]carbamate | 著者 | Wang, Y, Guo, S. | 登録日 | 2014-04-28 | 公開日 | 2015-06-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo. J.Biol.Chem., 290, 2015
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5G4C
| Human SIRT2 catalyse short chain fatty acyl lysine | 分子名称: | CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE, NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2, SIRT2, ... | 著者 | Wang, Y. | 登録日 | 2016-05-09 | 公開日 | 2017-05-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | SIRT2 Reverses 4-Oxononanoyl Lysine Modification on Histones. J. Am. Chem. Soc., 138, 2016
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4PF7
| Crystal structure of insulin degrading enzyme complexed with inhibitor | 分子名称: | (2S)-2-amino-N-{(1S)-1-cyclohexyl-2-[(4-methylphenyl)amino]-2-oxoethyl}-4-(methylselanyl)butanamide, Insulin-degrading enzyme, ZINC ION | 著者 | Wang, Y, Guo, S. | 登録日 | 2014-04-28 | 公開日 | 2015-06-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo. J.Biol.Chem., 290, 2015
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3QGC
| Crystal structure of FBF-2 R288Y mutant in complex with gld-1 FBEa A7U mutant | 分子名称: | 5'-R(*UP*GP*UP*GP*CP*CP*UP*UP*A)-3', Fem-3 mRNA-binding factor 2 | 著者 | Wang, Y, Qiu, C, Koh, Y.Y, Opperman, L, Gross, L, Hall, T.M.T, Wickens, M. | 登録日 | 2011-01-24 | 公開日 | 2011-03-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Stacking interactions in PUF-RNA complexes. Rna, 17, 2011
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4PES
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5XG8
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5Y03
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5Z2X
| Structure of Alcohol dehydrogenase from Kluyveromyces polyspora(KpADH) | 分子名称: | 1,2-ETHANEDIOL, Alcohol dehydrogenase, DI(HYDROXYETHYL)ETHER, ... | 著者 | Wang, Y, Zhou, J.Y, Hou, X.D, Xu, G.C, Wu, L, Rao, Y.J, ZHou, J.H, Ni, Y. | 登録日 | 2018-01-04 | 公開日 | 2019-01-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structural Insight into Enantioselective Inversion of an Alcohol Dehydrogenase Reveals a "Polar Gate" in Stereorecognition of Diaryl Ketones. J. Am. Chem. Soc., 140, 2018
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5ZED
| Crystal structure of Kluyveromyces polyspora ADH (KpADH) mutant (E214V/T215S) | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Uncharacterized protein ADH | 著者 | Wang, Y, Zhou, J.Y, Hou, X.D, Xu, G.C, Wu, L, Rao, Y.J, ZHou, J.H, Ni, Y. | 登録日 | 2018-02-27 | 公開日 | 2019-01-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | 主引用文献 | Structural Insight into Enantioselective Inversion of an Alcohol Dehydrogenase Reveals a "Polar Gate" in Stereorecognition of Diaryl Ketones. J. Am. Chem. Soc., 140, 2018
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8XAU
| Cryo-EM structure of HerA | 分子名称: | ATP-binding protein | 著者 | Wang, Y, Deng, Z. | 登録日 | 2023-12-05 | 公開日 | 2024-06-05 | 最終更新日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Molecular and structural basis of an ATPase-nuclease dual-enzyme anti-phage defense complex. Cell Res., 34, 2024
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7BXH
| MavC-Lpg2149 complex | 分子名称: | Lpg2149, MavC | 著者 | Gao, P, Wang, Y. | 登録日 | 2020-04-19 | 公開日 | 2020-05-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors. Nat Commun, 11, 2020
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8XAV
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6LYI
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2I0G
| Benzopyrans are Selective Estrogen Receptor beta Agonists (SERBAs) with Novel Activity in Models of Benign Prostatic Hyperplasia | 分子名称: | (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL, Estrogen receptor beta | 著者 | Wang, Y. | 登録日 | 2006-08-10 | 公開日 | 2006-10-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Benzopyrans are selective estrogen receptor Beta agonists with novel activity in models of benign prostatic hyperplasia. J.Med.Chem., 49, 2006
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2I0J
| Benzopyrans are Selective Estrogen Receptor beta Agonists (SERBAs) with Novel Activity in Models of Benign Prostatic Hyperplasia | 分子名称: | (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL, Estrogen receptor alpha | 著者 | Wang, Y. | 登録日 | 2006-08-10 | 公開日 | 2006-10-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Benzopyrans are selective estrogen receptor Beta agonists with novel activity in models of benign prostatic hyperplasia. J.Med.Chem., 49, 2006
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7BXG
| MavC-UBE2N-Ub complex | 分子名称: | MavC, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N | 著者 | Gao, P, Wang, Y. | 登録日 | 2020-04-19 | 公開日 | 2020-05-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.705 Å) | 主引用文献 | Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors. Nat Commun, 11, 2020
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6NOD
| Crystal structure of C. elegans PUF-8 in complex with RNA | 分子名称: | PUF (Pumilio/FBF) domain-containing, RNA (5'-R(P*UP*GP*UP*AP*UP*AP*UP*A)-3') | 著者 | Wang, Y, McCann, K.L, Qiu, C, Hall, T.M.T. | 登録日 | 2019-01-16 | 公開日 | 2019-01-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.547 Å) | 主引用文献 | Engineering a conserved RNA regulatory protein repurposes its biological function in vivo . Elife, 8, 2019
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6LYH
| Crystal structure of tea N9-methyltransferase CkTcS in complex with SAH and 1,3,7-trimethyluric acid | 分子名称: | 1,3,7-trimethyl-9H-purine-2,6,8-trione, N-methyltransferase CkTcS, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Wang, Y, Zhang, Z.-M. | 登録日 | 2020-02-14 | 公開日 | 2020-03-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.15000319 Å) | 主引用文献 | Identification and characterization of N9-methyltransferase involved in converting caffeine into non-stimulatory theacrine in tea. Nat Commun, 11, 2020
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7JOF
| Calcium-bound C2A Domain from Human Dysferlin | 分子名称: | CALCIUM ION, Isoform 6 of Dysferlin | 著者 | Tadayon, R, Wang, Y, Santamaria, L, Mercier, P, Forristal, C, Shaw, G.S. | 登録日 | 2020-08-06 | 公開日 | 2021-06-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Calcium binds and rigidifies the dysferlin C2A domain in a tightly coupled manner. Biochem.J., 478, 2021
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2KKT
| Solution structure of the SCA7 domain of human Ataxin-7-L3 protein | 分子名称: | Ataxin-7-like protein 3, ZINC ION | 著者 | Wang, Y, Atkinson, A.R, Bonnet, J, Romier, C, Kieffer, B. | 登録日 | 2009-06-29 | 公開日 | 2010-06-16 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Histone deubiquitination by SAGA is modulated by an atypical zinc finger domain of Ataxin-7 To be Published
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2KKR
| Solution structure of SCA7 zinc finger domain from human ataxin-7 protein | 分子名称: | Ataxin-7, ZINC ION | 著者 | Wang, Y, Atkinson, A.R, Bonnet, J, Romier, C, Kieffer, B, Structural Proteomics in Europe (SPINE) | 登録日 | 2009-06-29 | 公開日 | 2010-06-09 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Histone deubiquitination by SAGA is modulated by an atypical zinc finger domain of Ataxin-7 To be Published
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