5ZED
Crystal structure of Kluyveromyces polyspora ADH (KpADH) mutant (E214V/T215S)
Summary for 5ZED
Entry DOI | 10.2210/pdb5zed/pdb |
Descriptor | Uncharacterized protein ADH, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total) |
Functional Keywords | alcohol dehydrogenase(kpadh), nadph, isomerase |
Biological source | Vanderwaltozyma polyspora DSM 70294 (Kluyveromyces polysporus) |
Total number of polymer chains | 2 |
Total formula weight | 79297.08 |
Authors | Wang, Y.,Zhou, J.Y.,Hou, X.D.,Xu, G.C.,Wu, L.,Rao, Y.J.,ZHou, J.H.,Ni, Y. (deposition date: 2018-02-27, release date: 2019-01-02, Last modification date: 2023-11-22) |
Primary citation | Zhou, J.Y.,Wang, Y.,Xu, G.C.,Wu, L.,Han, R.Z.,Schwaneberg, U.,Rao, Y.J.,Zhao, Y.L.,Zhou, J.H.,Ni, Y. Structural Insight into Enantioselective Inversion of an Alcohol Dehydrogenase Reveals a "Polar Gate" in Stereorecognition of Diaryl Ketones. J. Am. Chem. Soc., 140:12645-12654, 2018 Cited by PubMed: 30247889DOI: 10.1021/jacs.8b08640 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.199 Å) |
Structure validation
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