3FJ4
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![BU of 3fj4 by Molmil](/molmil-images/mine/3fj4) | Crystal structure of muconate lactonizing enzyme from Pseudomonas Fluorescens complexed with muconolactone | 分子名称: | MAGNESIUM ION, Muconate cycloisomerase, [(2S)-5-oxo-2,5-dihydrofuran-2-yl]acetic acid | 著者 | Fedorov, A.A, Fedorov, E.V, Sakai, A, Gerlt, J.A, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2008-12-14 | 公開日 | 2009-03-31 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes Biochemistry, 48, 2009
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5DIE
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![BU of 5die by Molmil](/molmil-images/mine/5die) | Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a trifluoro-substituted A-CD ring estrogen derivative (1S,3aR,5S,7aS)-7a-methyl-5-(2,3,5-trifluoro-4-hydroxyphenyl)octahydro-1H-inden-1-ol | 分子名称: | (1S,3aR,5S,7aS)-7a-methyl-5-(2,3,5-trifluoro-4-hydroxyphenyl)octahydro-1H-inden-1-ol, Estrogen receptor, Nuclear receptor coactivator 2 | 著者 | Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W. | 登録日 | 2015-08-31 | 公開日 | 2016-05-04 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016
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3FGU
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![BU of 3fgu by Molmil](/molmil-images/mine/3fgu) | Catalytic complex of Human Glucokinase | 分子名称: | Glucokinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Petit, P, Lagarde, A, Boutin, J.A, Ferry, G, Vuillard, L. | 登録日 | 2008-12-08 | 公開日 | 2009-12-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | The active conformation of human glucokinase is not altered by allosteric activators Acta Crystallogr.,Sect.D, 67, 2011
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1SH0
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![BU of 1sh0 by Molmil](/molmil-images/mine/1sh0) | Crystal Structure of Norwalk Virus Polymerase (Triclinic) | 分子名称: | RNA Polymerase | 著者 | Ng, K.K, Pendas-Franco, N, Rojo, J, Boga, J.A, Machin, A, Alonso, J.M, Parra, F. | 登録日 | 2004-02-24 | 公開日 | 2004-03-09 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Crystal structure of norwalk virus polymerase reveals the carboxyl terminus in the active site cleft. J.Biol.Chem., 279, 2004
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5A46
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![BU of 5a46 by Molmil](/molmil-images/mine/5a46) | FGFR1 in complex with dovitinib | 分子名称: | 1,2-ETHANEDIOL, 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one, FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, ... | 著者 | Klein, T, Vajpai, N, Phillips, J.J, Davies, G, Holdgate, G.A, Phillips, C, Tucker, J.A, Norman, R.A, Scott, A.S, Higazi, D.R, Lowe, D, Thompson, G.S, Breeze, A.L. | 登録日 | 2015-06-05 | 公開日 | 2015-08-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Structural and Dynamic Insights Into the Energetics of Activation Loop Rearrangement in Fgfr1 Kinase. Nat.Commun., 6, 2015
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7JNH
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![BU of 7jnh by Molmil](/molmil-images/mine/7jnh) | Crystal structure of a double-ENE RNA stability element in complex with a 28-mer poly(A) RNA | 分子名称: | 28-mer poly(A) RNA, COBALT HEXAMMINE(III), Core double ENE RNA (Xtal construct) from Oryza sativa transposon,Core double ENE RNA (Xtal construct) from Oryza sativa transposon, ... | 著者 | Torabi, S.F, Vaidya, A.T, Tycowski, K.T, DeGregorio, S.J, Wang, J, Shu, M.D, Steitz, T.A, Steitz, J.A. | 登録日 | 2020-08-04 | 公開日 | 2021-01-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | RNA stabilization by a poly(A) tail 3'-end binding pocket and other modes of poly(A)-RNA interaction. Science, 371, 2021
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3ZJU
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![BU of 3zju by Molmil](/molmil-images/mine/3zju) | Ternary complex of E .coli leucyl-tRNA synthetase, tRNA(Leu) and the benzoxaborole AN3016 in the editing conformation | 分子名称: | LEUCYL-TRNA SYNTHETASE, MAGNESIUM ION, TRNALEU5 UAA ISOACCEPTOR | 著者 | Cusack, S, Palencia, A, Crepin, T, Hernandez, V, Akama, T, Baker, S.J, Bu, W, Feng, L, Freund, Y.R, Liu, L, Meewan, M, Mohan, M, Mao, W, Rock, F.L, Sexton, H, Sheoran, A, Zhang, Y, Zhang, Y, Zhou, Y, Nieman, J.A, Anugula, M.R, Keramane, E.M, Savariraj, K, Reddy, D.S, Sharma, R, Subedi, R, Singh, R, OLeary, A, Simon, N.L, DeMarsh, P.L, Mushtaq, S, Warner, M, Livermore, D.M, Alley, M.R.K, Plattner, J.J. | 登録日 | 2013-01-18 | 公開日 | 2013-04-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria. Antimicrob.Agents Chemother., 57, 2013
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7JOA
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![BU of 7joa by Molmil](/molmil-images/mine/7joa) | 2:1 cGAS-nucleosome complex | 分子名称: | Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1, ... | 著者 | Boyer, J.A, Spangler, C.J, Strauss, J.D, Cesmat, A.P, Liu, P, McGinty, R.K, Zhang, Q. | 登録日 | 2020-08-06 | 公開日 | 2020-09-16 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of nucleosome-dependent cGAS inhibition. Science, 370, 2020
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1UJL
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![BU of 1ujl by Molmil](/molmil-images/mine/1ujl) | Solution Structure of the HERG K+ channel S5-P extracellular linker | 分子名称: | Potassium voltage-gated channel subfamily H member 2 | 著者 | Torres, A.M, Bansal, P.S, Sunde, M, Clarke, C.E, Bursill, J.A, Smith, D.J, Bauskin, A, Breit, S.N, Campbell, T.J, Alewood, P.F, Kuchel, P.W, Vandenberg, J.I. | 登録日 | 2003-08-05 | 公開日 | 2003-11-04 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the HERG K+ channel S5P extracellular linker: role of an amphipathic alpha-helix
in C-type inactivation. J.Biol.Chem., 278, 2003
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5AA4
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3ZQ4
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![BU of 3zq4 by Molmil](/molmil-images/mine/3zq4) | Unusual, dual endo- and exo-nuclease activity in the degradosome explained by crystal structure analysis of RNase J1 | 分子名称: | CALCIUM ION, RIBONUCLEASE J 1, ZINC ION | 著者 | Newman, J.A, Hewitt, L, Rodrigues, C, Solovyova, A, Harwood, C.R, Lewis, R.J. | 登録日 | 2011-06-07 | 公開日 | 2011-09-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Unusual, Dual Endo- and Exonuclease Activity in the Degradosome Explained by Crystal Structure Analysis of Rnase J1. Structure, 19, 2011
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3ZLH
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![BU of 3zlh by Molmil](/molmil-images/mine/3zlh) | Structure of group A Streptococcal enolase | 分子名称: | ENOLASE | 著者 | Cork, A.J, Ericsson, D.J, Law, R.H.P, Casey, L.W, Valkov, E, Bertozzi, C, Stamp, A, Aquilina, J.A, Whisstock, J.C, Walker, M.J, Kobe, B. | 登録日 | 2013-01-31 | 公開日 | 2014-02-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Stability of the Octameric Structure Affects Plasminogen-Binding Capacity of Streptococcal Enolase. Plos One, 10, 2015
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3G0D
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![BU of 3g0d by Molmil](/molmil-images/mine/3g0d) | Crystal structure of dipeptidyl peptidase IV in complex with a pyrimidinedione inhibitor 2 | 分子名称: | 2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, Z, Wallace, M.B, Feng, J, Stafford, J.A, Kaldor, S.W, Shi, L, Skene, R.J, Aertgeerts, K, Lee, B, Jennings, A, Xu, R, Kassel, D, Webb, D.R, Gwaltney, S.L. | 登録日 | 2009-01-27 | 公開日 | 2010-02-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Design and Synthesis of Pyrimidinone and Pyrimidinedione Inhibitors of Dipeptidyl Peptidase IV. J.Med.Chem., 54, 2011
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3G1X
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![BU of 3g1x by Molmil](/molmil-images/mine/3g1x) | Crystal structure of the mutant D70G of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with uridine 5'-monophosphate | 分子名称: | CHLORIDE ION, Orotidine 5'-phosphate decarboxylase, URIDINE-5'-MONOPHOSPHATE | 著者 | Fedorov, A.A, Fedorov, E.V, Chan, K.K, Gerlt, J.A, Almo, S.C. | 登録日 | 2009-01-30 | 公開日 | 2009-06-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization. Biochemistry, 48, 2009
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3ZP5
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![BU of 3zp5 by Molmil](/molmil-images/mine/3zp5) | Crystal structure of the DNA binding ETS domain of the human protein FEV in complex with DNA | 分子名称: | 5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP)-3', 5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP)-3', PROTEIN FEV | 著者 | Newman, J.A, Cooper, C.D.O, Krojer, T, Shrestha, L, Allerston, C.K, Vollmar, M, Arrowsmith, C.H, Burgess-Brown, N, Edwards, A, von Delft, F, Gileadi, O. | 登録日 | 2013-02-26 | 公開日 | 2013-03-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation. J.Biol.Chem., 290, 2015
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7JRG
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![BU of 7jrg by Molmil](/molmil-images/mine/7jrg) | Plant Mitochondrial complex III2 from Vigna radiata | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Alpha-MPP, ... | 著者 | Maldonado, M, Letts, J.A. | 登録日 | 2020-08-12 | 公開日 | 2021-01-20 | 最終更新日 | 2021-02-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Atomic structures of respiratory complex III 2 , complex IV, and supercomplex III 2 -IV from vascular plants. Elife, 10, 2021
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3ZYC
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![BU of 3zyc by Molmil](/molmil-images/mine/3zyc) | DYNAMIN 1 GTPASE GED FUSION DIMER COMPLEXED WITH GMPPCP | 分子名称: | DYNAMIN-1, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | 著者 | Chappie, J.S, Mears, J.A, Fang, S, Leonard, M, Schmid, S.L, Milligan, R.A, Hinshaw, J.E, Dyda, F. | 登録日 | 2011-08-22 | 公開日 | 2011-10-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A Pseudoatomic Model of the Dynamin Polymer Identifies a Hydrolysis-Dependent Powerstroke. Cell(Cambridge,Mass.), 147, 2011
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3ZBT
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![BU of 3zbt by Molmil](/molmil-images/mine/3zbt) | Ferredoxin-NADP Reductase Mutant with SER 59 Replaced by ALA (S59A) | 分子名称: | FERREDOXIN-NADP REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Martinez-Julvez, M, Herguedas, B, Sanchez-Azqueta, A, Hervas, M, Navarro, J.A, Medina, M. | 登録日 | 2012-11-13 | 公開日 | 2013-11-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | A Hydrogen Bond Network in the Active Site of Anabaena Ferredoxin-Nadp(+) Reductase Modulates its Catalytic Efficiency. Biochim.Biophys.Acta, 1837, 2013
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5DID
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![BU of 5did by Molmil](/molmil-images/mine/5did) | Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a difluoro-substituted A-CD ring estrogen derivative (1S,3aR,5S,7aS)-5-(2,3-difluoro-4-hydroxyphenyl)-7a-methyloctahydro-1H-inden-1-ol | 分子名称: | (1S,3aR,5S,7aS)-5-(2,3-difluoro-4-hydroxyphenyl)-7a-methyloctahydro-1H-inden-1-ol, Estrogen receptor, Nuclear receptor coactivator 2 | 著者 | Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W. | 登録日 | 2015-08-31 | 公開日 | 2016-05-04 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016
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3ZLB
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7K1Y
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3ZUQ
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![BU of 3zuq by Molmil](/molmil-images/mine/3zuq) | Crystal structure of an engineered botulinum neurotoxin type B - derivative, LC-B-GS-Hn-B | 分子名称: | BOTULINUM NEUROTOXIN TYPE B, ZINC ION | 著者 | Masuyer, G, Stancombe, P, Chaddock, J.A, Acharya, K.R. | 登録日 | 2011-07-19 | 公開日 | 2011-12-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structures of Engineered Clostridium Botulinum Neurotoxin Derivatives Acta Crystallogr.,Sect.F, 67, 2011
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1RWZ
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![BU of 1rwz by Molmil](/molmil-images/mine/1rwz) | Crystal Structure of Proliferating Cell Nuclear Antigen (PCNA) from A. fulgidus | 分子名称: | DNA polymerase sliding clamp | 著者 | Chapados, B.R, Hosfield, D.J, Han, S, Qiu, J, Yelent, B, Shen, B, Tainer, J.A. | 登録日 | 2003-12-17 | 公開日 | 2004-01-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair Cell(Cambridge,Mass.), 116, 2004
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1RXM
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![BU of 1rxm by Molmil](/molmil-images/mine/1rxm) | C-terminal region of FEN-1 bound to A. fulgidus PCNA | 分子名称: | DNA polymerase sliding clamp, consensus FEN-1 peptide | 著者 | Chapados, B.R, Hosfield, D.J, Han, S, Qiu, J, Yelent, B, Shen, B, Tainer, J.A. | 登録日 | 2003-12-18 | 公開日 | 2004-01-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair Cell(Cambridge,Mass.), 116, 2004
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3USQ
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![BU of 3usq by Molmil](/molmil-images/mine/3usq) | Structure of D159S/Y194F glycogenin mutant truncated at residue 270 | 分子名称: | CHLORIDE ION, GLYCEROL, Glycogenin-1 | 著者 | Issoglio, F.M, Carrizo, M.E, Romero, J.M, Curtino, J.A. | 登録日 | 2011-11-23 | 公開日 | 2011-12-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Mechanisms of monomeric and dimeric glycogenin autoglucosylation. J.Biol.Chem., 287, 2012
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