6LT0
 
 | | cryo-EM structure of C9ORF72-SMCR8-WDR41 | | 分子名称: | Guanine nucleotide exchange C9orf72, Guanine nucleotide exchange protein SMCR8, WD repeat-containing protein 41 | | 著者 | Tang, D, Sheng, J, Xu, L, Zhan, X, Yan, C, Qi, S. | | 登録日 | 2020-01-21 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structure of C9ORF72-SMCR8-WDR41 reveals the role as a GAP for Rab8a and Rab11a.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6LPQ
 | | Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with D-malate (D-MAL) | | 分子名称: | D-2-hydroxyglutarate dehydrogenase, mitochondrial, D-MALATE, ... | | 著者 | Yang, J, Zhu, H, Ding, J. | | 登録日 | 2020-01-12 | | 公開日 | 2021-01-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations.
Cell Discov, 7, 2021
|
|
6LPN
 | | Crystal structure of human D-2-hydroxyglutarate dehydrogenase in apo form | | 分子名称: | D-2-hydroxyglutarate dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Yang, J, Zhu, H, Ding, J. | | 登録日 | 2020-01-12 | | 公開日 | 2021-01-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.206 Å) | | 主引用文献 | Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations.
Cell Discov, 7, 2021
|
|
6LPT
 | | Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with D-lactate (D-LAC) | | 分子名称: | D-2-hydroxyglutarate dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Yang, J, Zhu, H, Ding, J. | | 登録日 | 2020-01-12 | | 公開日 | 2021-01-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.621 Å) | | 主引用文献 | Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations.
Cell Discov, 7, 2021
|
|
6LPX
 | | Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with 2-oxoglutarate (2-OG) | | 分子名称: | 2-OXOGLUTARIC ACID, D-2-hydroxyglutarate dehydrogenase, mitochondrial, ... | | 著者 | Yang, J, Zhu, H, Ding, J. | | 登録日 | 2020-01-12 | | 公開日 | 2021-01-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations.
Cell Discov, 7, 2021
|
|
6LPU
 | | Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with L-2-hydroxyglutarate (L-2-HG) | | 分子名称: | (2S)-2-HYDROXYPENTANEDIOIC ACID, D-2-hydroxyglutarate dehydrogenase, mitochondrial, ... | | 著者 | Yang, J, Zhu, H, Ding, J. | | 登録日 | 2020-01-12 | | 公開日 | 2021-01-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.923 Å) | | 主引用文献 | Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations.
Cell Discov, 7, 2021
|
|
6ITW
 | |
7R8S
 | |
6J4A
 | |
6J4M
 | | Thermal treated soybean seed H-2 ferritin | | 分子名称: | Ferritin, MAGNESIUM ION | | 著者 | Zhang, X, Zang, J, Chen, H, Zhou, K, Zhao, G. | | 登録日 | 2019-01-09 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.598 Å) | | 主引用文献 | Thermostability of protein nanocages: the effect of natural extra peptide on the exterior surface.
Rsc Adv, 9, 2019
|
|
6J4J
 | | soybean seed H-2 ferritin | | 分子名称: | Ferritin, MAGNESIUM ION | | 著者 | Zhang, X, Zang, J, Chen, H, Zhao, G. | | 登録日 | 2019-01-09 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | | 主引用文献 | Thermostability of protein nanocages: the effect of natural extra peptide on the exterior surface.
Rsc Adv, 9, 2019
|
|
8YN5
 | | Cryo-EM structure of histamine H3 receptor in complex with histamine and Gi | | 分子名称: | Antibody fragment scFv16, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhang, X, Liu, G, Li, X, Gong, W. | | 登録日 | 2024-03-10 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural basis of ligand recognition and activation of the histamine receptor family.
Nat Commun, 15, 2024
|
|
8YN9
 | | Cryo-EM structure of histamine H4 receptor in complex with histamine and Gi | | 分子名称: | Antibody fragment scFv16, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhang, X, Liu, G, Li, X, Gong, W. | | 登録日 | 2024-03-10 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Structural basis of ligand recognition and activation of the histamine receptor family.
Nat Commun, 15, 2024
|
|
8YNA
 | | Cryo-EM structure of histamine H4 receptor in complex with immepip and Gi | | 分子名称: | 4-(1H-imidazol-5-ylmethyl)piperidine, Antibody fragment scFv16, CHOLESTEROL, ... | | 著者 | Zhang, X, Liu, G, Li, X, Gong, W. | | 登録日 | 2024-03-10 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | | 主引用文献 | Structural basis of ligand recognition and activation of the histamine receptor family.
Nat Commun, 15, 2024
|
|
5KIY
 | | p97 ND1-A232E in complex with VIMP | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Selenoprotein S, ... | | 著者 | Tang, W.K, Xia, D. | | 登録日 | 2016-06-17 | | 公開日 | 2017-12-20 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Structural basis for nucleotide-modulated p97 association with the ER membrane.
Cell Discov, 3, 2017
|
|
5KIU
 | |
8YN2
 | | Cryo-EM structure of histamine H1 receptor in complex with histamine and miniGq | | 分子名称: | Antibody fragment scFv16, CHOLESTEROL, Engineered guanine nucleotide-binding protein G(q) subunit alpha, ... | | 著者 | Zhang, X, Liu, G, Li, X, Gong, W. | | 登録日 | 2024-03-10 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | | 主引用文献 | Structural basis of ligand recognition and activation of the histamine receptor family.
Nat Commun, 15, 2024
|
|
8YN4
 | | Cryo-EM structure of histamine H2 receptor in complex with histamine and miniGq | | 分子名称: | Antibody fragment scFv16, CHOLESTEROL, Engineered guanine nucleotide-binding protein G(q) subunit alpha, ... | | 著者 | Zhang, X, Liu, G, Li, X, Gong, W. | | 登録日 | 2024-03-10 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | | 主引用文献 | Structural basis of ligand recognition and activation of the histamine receptor family.
Nat Commun, 15, 2024
|
|
8YN6
 | | Cryo-EM structure of histamine H3 receptor in complex with imetit and Gi | | 分子名称: | 2-(1~{H}-imidazol-5-yl)ethyl carbamimidothioate, Antibody fragment scFv16, CHOLESTEROL, ... | | 著者 | Zhang, X, Liu, G, Li, X, Gong, W. | | 登録日 | 2024-03-10 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | Structural basis of ligand recognition and activation of the histamine receptor family.
Nat Commun, 15, 2024
|
|
8YN3
 | | Cryo-EM structure of histamine H2 receptor in complex with histamine and miniGs | | 分子名称: | CHOLESTEROL, Engineered guanine nucleotide,binding protein G(s) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhang, X, Liu, G, Li, X, Gong, W. | | 登録日 | 2024-03-10 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | | 主引用文献 | Structural basis of ligand recognition and activation of the histamine receptor family.
Nat Commun, 15, 2024
|
|
8GZ4
 | | Crystal structure of MPXV phosphatase | | 分子名称: | Dual specificity protein phosphatase H1, PHOSPHATE ION | | 著者 | Yang, H.T, Wang, W, Huang, H.J, Ji, X.Y. | | 登録日 | 2022-09-25 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | | 主引用文献 | Crystal structure of monkeypox H1 phosphatase, an antiviral drug target.
Protein Cell, 14, 2023
|
|
8Y92
 | | structure of NET-Atomoxetine in outward-open state | | 分子名称: | (3R)-N-methyl-3-(2-methylphenoxy)-3-phenyl-propan-1-amine, CHLORIDE ION, SODIUM ION, ... | | 著者 | Zhang, H, Xu, E.H, Jiang, Y. | | 登録日 | 2024-02-06 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | | 主引用文献 | Dimerization and antidepressant recognition at noradrenaline transporter.
Nature, 630, 2024
|
|
8Y91
 | | Structure of NET-nomifensine in outward-open state | | 分子名称: | (4S)-2-methyl-4-phenyl-3,4-dihydro-1H-isoquinolin-8-amine, CHLORIDE ION, SODIUM ION, ... | | 著者 | Zhang, H, Xu, E.H, Jiang, Y. | | 登録日 | 2024-02-06 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | Dimerization and antidepressant recognition at noradrenaline transporter.
Nature, 630, 2024
|
|
8Y90
 | | Structure of NET-Nefopam in outward-open state | | 分子名称: | (1S)-5-methyl-1-phenyl-1,3,4,6-tetrahydro-2,5-benzoxazocine, CHLORIDE ION, SODIUM ION, ... | | 著者 | Zhang, H, Xu, E.H, Jiang, Y. | | 登録日 | 2024-02-06 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Dimerization and antidepressant recognition at noradrenaline transporter.
Nature, 630, 2024
|
|
7FAE
 | | S protein of SARS-CoV-2 in complex bound with P36-5D2(state2) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, P36-5D2 heavy chain, ... | | 著者 | Zhang, L, Wang, X, Shan, S, Zhang, S. | | 登録日 | 2021-07-06 | | 公開日 | 2021-12-22 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | | 主引用文献 | A Potent and Protective Human Neutralizing Antibody Against SARS-CoV-2 Variants.
Front Immunol, 12, 2021
|
|
