6MTR
 
 | | Crystal structure of VRC43.01 Fab | | 分子名称: | Antibody VRC43.01 Fab heavy chain, Antibody VRC43.01 Fab light chain | | 著者 | Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Zhang, B, Doria-Rose, N.A, Kwong, P.D. | | 登録日 | 2018-10-21 | | 公開日 | 2019-03-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | | 主引用文献 | Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
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6MTS
 | | Crystal structure of VRC43.03 Fab | | 分子名称: | Antibody VRC43.03 Fab heavy chain, Antibody VRC43.03 Fab light chain | | 著者 | Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Doria-Rose, N.A, Kwong, P.D. | | 登録日 | 2018-10-21 | | 公開日 | 2019-03-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.437 Å) | | 主引用文献 | Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
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6MTP
 | | Crystal structure of VRC42.04 Fab in complex with gp41 peptide | | 分子名称: | Antibody VRC42.04 Fab heavy chain, Antibody VRC42.04 Fab light chain, RV217 founder virus gp41 peptide | | 著者 | Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Zhang, B, Doria-Rose, N.A, Kwong, P.D. | | 登録日 | 2018-10-21 | | 公開日 | 2019-03-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.036 Å) | | 主引用文献 | Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
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6MTT
 | | Crystal structure of VRC46.01 Fab in complex with gp41 peptide | | 分子名称: | Antibody VRC46.01 Fab heavy chain, Antibody VRC46.01 Fb light chain, RV217 founder virus gp41 peptide | | 著者 | Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Veradi, R, Doria-Rose, N.A, Kwong, P.D. | | 登録日 | 2018-10-21 | | 公開日 | 2019-03-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
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6MTQ
 | | Crystal structure of VRC42.N1 Fab in complex with T117-F MPER scaffold | | 分子名称: | Antibody VRC42.N1 Fab heavy chain, Antibody VRC42.N1 Fab light chain, VRC42 epitope T117-F scaffold | | 著者 | Kwon, Y.D, Law, W.H, Veradi, R, Doria-Rose, N.A, Kwong, P.D. | | 登録日 | 2018-10-21 | | 公開日 | 2019-03-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
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7Z1H
 | | VAR2CSA APO | | 分子名称: | VAR2CSA APO | | 著者 | Raghavan, S.S.R, Wang, K.T. | | 登録日 | 2022-02-24 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA.
Plos Pathog., 18, 2022
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7Z12
 | | VAR2 complex with PAM1.4 | | 分子名称: | PAM1.4, Heavy Chain, light Chain, ... | | 著者 | Raghavan, S.S.R, Wang, K.T. | | 登録日 | 2022-02-24 | | 公開日 | 2022-11-02 | | 最終更新日 | 2022-11-30 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA.
Plos Pathog., 18, 2022
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4WXM
 | | FleQ REC domain from Pseudomonas aeruginosa PAO1 | | 分子名称: | Transcriptional regulator FleQ | | 著者 | Su, T, Liu, S, Gu, L. | | 登録日 | 2014-11-14 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The REC domain mediated dimerization is critical for FleQ from Pseudomonas aeruginosa to function as a c-di-GMP receptor and flagella gene regulator
J.Struct.Biol., 192, 2015
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5TBM
 | | Crystal structure of PT2385 bound to HIF2a-B*:ARNT-B* complex | | 分子名称: | 3-{[(1S)-2,2-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl]oxy}-5-fluorobenzonitrile, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 | | 著者 | Du, X. | | 登録日 | 2016-09-12 | | 公開日 | 2016-09-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | A Small-Molecule Antagonist of HIF2 alpha Is Efficacious in Preclinical Models of Renal Cell Carcinoma.
Cancer Res., 76, 2016
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5AFX
 | | T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-1238 | | 分子名称: | FARNESYL PYROPHOSPHATE SYNTHASE, MAGNESIUM ION, [1-hydroxy-2-(1-nonyl-1H-3lambda~5~-imidazol-3-yl)ethane-1,1-diyl]bis(phosphonic acid) | | 著者 | Yang, G, Oldfield, E, No, J.H. | | 登録日 | 2015-01-27 | | 公開日 | 2015-10-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Inhibition of Trypanosoma Brucei Cell Growth by Lipophilic Bisphosphonates: An in Vitro and in Vivo Investigation.
Antimicrob.Agents Chemother., 59, 2015
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4H4C
 | | IspH in complex with (E)-4-fluoro-3-methylbut-2-enyl diphosphate | | 分子名称: | (2E)-4-fluoro-3-methylbut-2-en-1-yl trihydrogen diphosphate, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER | | 著者 | Span, I, Eisenreich, W, Jauch, J, Bacher, A, Groll, M. | | 登録日 | 2012-09-17 | | 公開日 | 2013-01-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structures of Fluoro, Amino, and Thiol Inhibitors Bound to the [Fe(4) S(4) ] Protein IspH.
Angew.Chem.Int.Ed.Engl., 52, 2013
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7OP1
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7OP8
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7OP5
 | | Cryo-EM structure of P5B-ATPase E2P | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, P5B-ATPase | | 著者 | Li, P, Gourdon, P. | | 登録日 | 2021-05-29 | | 公開日 | 2021-06-30 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structure and transport mechanism of P5B-ATPases.
Nat Commun, 12, 2021
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5AHU
 | | T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-1326 | | 分子名称: | FARNESYL PYROPHOSPHATE SYNTHASE, PUTATIVE, MAGNESIUM ION, ... | | 著者 | Yang, G, Oldfield, E, No, J.H. | | 登録日 | 2015-02-09 | | 公開日 | 2015-10-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Inhibition of Trypanosoma Brucei Cell Growth by Lipophilic Bisphosphonates: An in Vitro and in Vivo Investigation.
Antimicrob.Agents Chemother., 59, 2015
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4H4D
 | | IspH in complex with (E)-4-amino-3-methylbut-2-enyl diphosphate | | 分子名称: | (2E)-4-amino-3-methylbut-2-en-1-yl trihydrogen diphosphate, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER | | 著者 | Span, I, Eisenreich, W, Jauch, J, Bacher, A, Groll, M. | | 登録日 | 2012-09-17 | | 公開日 | 2013-01-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structures of Fluoro, Amino, and Thiol Inhibitors Bound to the [Fe(4) S(4) ] Protein IspH.
Angew.Chem.Int.Ed.Engl., 52, 2013
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4IKP
 | | Crystal structure of coactivator-associated arginine methyltransferase 1 with methylenesinefungin | | 分子名称: | (2S,5S)-2,6-diamino-5-{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}hexanoic acid, GLYCEROL, Histone-arginine methyltransferase CARM1, ... | | 著者 | Dong, A, Dombrovski, L, He, H, Ibanez, G, Wernimont, A, Zheng, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Luo, M, Wu, H, Structural Genomics Consortium (SGC) | | 登録日 | 2012-12-27 | | 公開日 | 2013-02-13 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A chemical probe of CARM1 alters epigenetic plasticity against breast cancer cell invasion.
Elife, 8, 2019
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4H4E
 | | IspH in complex with (E)-4-mercapto-3-methylbut-2-enyl diphosphate | | 分子名称: | (2E)-3-methyl-4-sulfanylbut-2-en-1-yl trihydrogen diphosphate, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER | | 著者 | Span, I, Eisenreich, W, Jauch, J, Bacher, A, Groll, M. | | 登録日 | 2012-09-17 | | 公開日 | 2013-01-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structures of Fluoro, Amino, and Thiol Inhibitors Bound to the [Fe(4) S(4) ] Protein IspH.
Angew.Chem.Int.Ed.Engl., 52, 2013
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4XP4
 | | X-ray structure of Drosophila dopamine transporter in complex with cocaine | | 分子名称: | 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, ANTIBODY FRAGMENT HEAVY CHAIN-PROTEIN, 9D5-HEAVY CHAIN, ... | | 著者 | Aravind, P, Wang, K, Gouaux, E. | | 登録日 | 2015-01-16 | | 公開日 | 2015-05-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Neurotransmitter and psychostimulant recognition by the dopamine transporter.
Nature, 521, 2015
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4XNU
 | | X-ray structure of Drosophila dopamine transporter in complex with nisoxetine | | 分子名称: | CHLORIDE ION, CHOLESTEROL, Integral membrane protein-dopamine transporter, ... | | 著者 | Aravind, P, Wang, K, Gouaux, E. | | 登録日 | 2015-01-16 | | 公開日 | 2015-05-13 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | | 主引用文献 | X-ray structures of Drosophila dopamine transporter in complex with nisoxetine and reboxetine.
Nat.Struct.Mol.Biol., 22, 2015
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4XP1
 | | X-ray structure of Drosophila dopamine transporter bound to neurotransmitter dopamine | | 分子名称: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Gouaux, E, Penmatsa, A, Wang, K. | | 登録日 | 2015-01-16 | | 公開日 | 2015-05-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Neurotransmitter and psychostimulant recognition by the dopamine transporter.
Nature, 521, 2015
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3VKA
 | | Crystal structure of MoeO5 soaked for 3 hours in FsPP | | 分子名称: | (2R)-3-(phosphonooxy)-2-{[(2Z,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy}propanoic acid, MAGNESIUM ION, MoeO5 | | 著者 | Ren, F, Ko, T.-P, Huang, C.-H, Guo, R.-T. | | 登録日 | 2011-11-11 | | 公開日 | 2012-05-09 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Insights into the mechanism of the antibiotic-synthesizing enzyme MoeO5 from crystal structures of different complexes
Angew.Chem.Int.Ed.Engl., 51, 2012
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4XP5
 | | X-ray structure of Drosophila dopamine transporter bound to cocaine analogue-RTI55 | | 分子名称: | 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Antibody fragment heavy chain-protein, 9D5-heavy chain, ... | | 著者 | Gouaux, E, Penmatsa, A, Wang, K. | | 登録日 | 2015-01-16 | | 公開日 | 2015-05-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Neurotransmitter and psychostimulant recognition by the dopamine transporter.
Nature, 521, 2015
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4XPB
 | | X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) bound to cocaine | | 分子名称: | Antibody fragment heavy chain-protein, 9D5-heavy chain, Antibody fragment light chain-protein, ... | | 著者 | Aravind, P, Wang, K, Gouaux, E. | | 登録日 | 2015-01-16 | | 公開日 | 2015-05-13 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Neurotransmitter and psychostimulant recognition by the dopamine transporter.
Nature, 521, 2015
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4XPT
 | | X-ray structure of Drosophila dopamine transporter with subsiteB mutations D121G/S426M and EL2 deletion of 162-201 in complex with substrate analogue 3,4 dichlorophen ethylamine | | 分子名称: | 2-(3,4-dichlorophenyl)ethanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Aravind, P, Wang, K, Gouaux, E. | | 登録日 | 2015-01-17 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.36 Å) | | 主引用文献 | Neurotransmitter and psychostimulant recognition by the dopamine transporter.
Nature, 521, 2015
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