3VG9
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![BU of 3vg9 by Molmil](/molmil-images/mine/3vg9) | Crystal structure of human adenosine A2A receptor with an allosteric inverse-agonist antibody at 2.7 A resolution | 分子名称: | 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, Adenosine receptor A2a, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Hino, T, Arakawa, T, Iwanari, H, Yurugi-Kobayashi, T, Ikeda-Suno, C, Nakada-Nakura, Y, Kusano-Arai, O, Weyand, S, Shimamura, T, Nomura, N, Cameron, A.D, Kobayashi, T, Hamakubo, T, Iwata, S, Murata, T. | 登録日 | 2011-08-04 | 公開日 | 2012-02-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody Nature, 482, 2012
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3VGA
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![BU of 3vga by Molmil](/molmil-images/mine/3vga) | Crystal structure of human adenosine A2A receptor with an allosteric inverse-agonist antibody at 3.1 A resolution | 分子名称: | 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, Adenosine receptor A2a, antibody fab fragment heavy chain, ... | 著者 | Hino, T, Arakawa, T, Iwanari, H, Yurugi-Kobayashi, T, Ikeda-Suno, C, Nakada-Nakura, Y, Kusano-Arai, O, Weyand, S, Shimamura, T, Nomura, N, Cameron, A.D, Kobayashi, T, Hamakubo, T, Iwata, S, Murata, T. | 登録日 | 2011-08-04 | 公開日 | 2012-02-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody Nature, 482, 2012
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5XAV
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![BU of 5xav by Molmil](/molmil-images/mine/5xav) | Structure of PhaC from Chromobacterium sp. USM2 | 分子名称: | Intracellular polyhydroxyalkanoate synthase | 著者 | Chek, M.F, Kim, S.Y, Mori, T, Arsad, H, Samian, M.R, Sudesh, K, Hakoshima, T. | 登録日 | 2017-03-15 | 公開日 | 2017-07-26 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.479 Å) | 主引用文献 | Structure of polyhydroxyalkanoate (PHA) synthase PhaC from Chromobacterium sp. USM2, producing biodegradable plastics Sci Rep, 7, 2017
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2Z7C
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![BU of 2z7c by Molmil](/molmil-images/mine/2z7c) | Crystal structure of chromatin protein alba from hyperthermophilic archaeon pyrococcus horikoshii | 分子名称: | ARGININE, DNA/RNA-binding protein Alba | 著者 | Hada, K, Nakashima, T, Osawa, T, Shimada, H, Kakuta, Y, Kimura, M. | 登録日 | 2007-08-17 | 公開日 | 2008-08-05 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure and functional analysis of an archaeal chromatin protein Alba from the hyperthermophilic archaeon Pyrococcus horikoshii OT3. Biosci.Biotechnol.Biochem., 72, 2008
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5YGY
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![BU of 5ygy by Molmil](/molmil-images/mine/5ygy) | Crystal Structure of BACE1 in complex with (S)-N-(3-(2-amino-6-(fluoromethyl)-4 -methyl-4H-1,3-oxazin-4-yl)-4-fluorophenyl)-5-cyanopicolinamide | 分子名称: | Beta-secretase 1, GLYCEROL, IODIDE ION, ... | 著者 | Fuchino, K, Mitsuoka, Y, Masui, M, Kurose, N, Yoshida, S, Komano, K, Yamamoto, T, Ogawa, M, Unemura, C, Hosono, M, Ito, H, Sakaguchi, G, Ando, S, Ohnishi, S, Kido, Y, Fukushima, T, Miyajima, H, Hiroyama, S, Koyabu, K, Dhuyvetter, D, Borghys, H, Gijsen, H, Yamano, Y, Iso, Y, Kusakabe, K. | 登録日 | 2017-09-27 | 公開日 | 2018-05-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Rational Design of Novel 1,3-Oxazine Based beta-Secretase (BACE1) Inhibitors: Incorporation of a Double Bond To Reduce P-gp Efflux Leading to Robust A beta Reduction in the Brain J. Med. Chem., 61, 2018
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3WDZ
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![BU of 3wdz by Molmil](/molmil-images/mine/3wdz) | Crystal Structure of Keap1 in Complex with phosphorylated p62 | 分子名称: | Kelch-like ECH-associated protein 1, Peptide from Sequestosome-1 | 著者 | Fukutomi, T, Takagi, K, Mizushima, T, Tanaka, K, Komatsu, M, Yamamoto, M. | 登録日 | 2013-06-26 | 公開日 | 2013-09-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy. Mol.Cell, 51, 2013
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7BQB
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![BU of 7bqb by Molmil](/molmil-images/mine/7bqb) | Solution NMR structure of NF6; de novo designed protein with a novel fold | 分子名称: | NF6 | 著者 | Kobayashi, N, Nagashima, T, Minami, S, Koga, R, Chikenji, G, Koga, N. | 登録日 | 2020-03-24 | 公開日 | 2021-03-24 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Exploration of novel alpha-beta-protein folds through de novo design Nat.Struct.Mol.Biol., 2023
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1DJ6
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![BU of 1dj6 by Molmil](/molmil-images/mine/1dj6) | COMPLEX OF A Z-DNA HEXAMER, D(CG)3, WITH SYNTHETIC POLYAMINE AT ROOM TEMPERATURE | 分子名称: | 5'-D(*CP*GP*CP*GP*CP*G)-3', MAGNESIUM ION, N,N'-BIS(2-AMINOETHYL)-1,2-ETHANEDIAMINE | 著者 | Ohishi, H, Tomita, K.-i, Nakanishi, I, Ohtsuchi, M, Hakoshima, T, Rich, A. | 登録日 | 1999-12-01 | 公開日 | 1999-12-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | The crystal structure of N1-[2-(2-amino-ethylamino)-ethyl]-ethane-1,2-diamine (polyamines) binding to the minor groove of d(CGCGCG)2, hexamer at room temperature FEBS Lett., 523, 2002
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1WG2
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1WRY
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![BU of 1wry by Molmil](/molmil-images/mine/1wry) | Solution structure of the SH3 domain-binding glutamic acid-rich-like protein | 分子名称: | SH3 domain-binding glutamic acid-rich-like protein | 著者 | Inoue, K, Miyamoto, K, Nagashima, T, Hayashi, F, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2004-10-29 | 公開日 | 2005-04-29 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the SH3 domain-binding glutamic acid-rich-like protein To be Published
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1WJ3
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![BU of 1wj3 by Molmil](/molmil-images/mine/1wj3) | Solution structure of the fourth fn3 domain of KIAA1496 protein | 分子名称: | KIAA1496 protein | 著者 | Inoue, K, Nagashima, T, Tochio, N, Kigawa, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2004-05-28 | 公開日 | 2004-11-28 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the fourth fn3 domain of KIAA1496 protein To be Published
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1WY6
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![BU of 1wy6 by Molmil](/molmil-images/mine/1wy6) | Crystal Structure of Hypothetical Protein [ST1625p] from Hyperthermophilic Archaeon Sulfolobus tokodaii | 分子名称: | hypothetical protein ST1625 | 著者 | Yoneda, K, Sakuraba, H, Tsuge, H, Katunuma, N, Kuramitsu, S, Kawabata, T, Ohshima, T. | 登録日 | 2005-02-07 | 公開日 | 2005-02-15 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The first crystal structure of an archaeal helical repeat protein. Acta Crystallogr.,Sect.F, 61, 2005
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5WYF
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![BU of 5wyf by Molmil](/molmil-images/mine/5wyf) | Structure of amino acid racemase, 2.12 A | 分子名称: | CADMIUM ION, Isoleucine 2-epimerase, N-[O-PHOSPHONO-PYRIDOXYL]-ISOLEUCINE | 著者 | Sakuraba, H, Mutaguchi, Y, Hayashi, J, Ohshima, T. | 登録日 | 2017-01-12 | 公開日 | 2017-04-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Crystal structure of the novel amino-acid racemase isoleucine 2-epimerase from Lactobacillus buchneri. Acta Crystallogr D Struct Biol, 73, 2017
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8HMO
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5XVH
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![BU of 5xvh by Molmil](/molmil-images/mine/5xvh) | Crystal structure of the NADP+ and tartrate-bound complex of L-serine 3-dehydrogenase from the hyperthermophilic archaeon Pyrobaculum calidifontis | 分子名称: | 6-phosphogluconate dehydrogenase, NAD-binding protein, ACETIC ACID, ... | 著者 | Yoneda, K, Sakuraba, H, Ohshima, T. | 登録日 | 2017-06-28 | 公開日 | 2018-02-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Crystal structure of the NADP+and tartrate-bound complex of L-serine 3-dehydrogenase from the hyperthermophilic archaeon Pyrobaculum calidifontis. Extremophiles, 22, 2018
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5X5I
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![BU of 5x5i by Molmil](/molmil-images/mine/5x5i) | The X-ray crystal structure of a TetR family transcription regulator RcdA involved in the regulation of biofilm formation in Escherichia coli | 分子名称: | HTH-type transcriptional regulator RcdA | 著者 | Sugino, H, Usui, M, Shimada, T, Nakano, M, Ogasawara, H, Ishihama, A, Hirata, A. | 登録日 | 2017-02-16 | 公開日 | 2017-12-27 | 実験手法 | X-RAY DIFFRACTION (2.554 Å) | 主引用文献 | A structural sketch of RcdA, a transcription factor controlling the master regulator of biofilm formation. FEBS Lett., 591, 2017
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3WXB
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![BU of 3wxb by Molmil](/molmil-images/mine/3wxb) | Crystal structure of NADPH bound carbonyl reductase from chicken fatty liver | 分子名称: | 1,2-ETHANEDIOL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Uncharacterized protein | 著者 | Yoneda, K, Sakuraba, H, Fukuda, Y, Sone, T, Araki, T, Ohshima, T. | 登録日 | 2014-07-29 | 公開日 | 2015-07-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | A novel NAD(P)H-dependent carbonyl reductase specifically expressed in the thyroidectomized chicken fatty liver: catalytic properties and crystal structure. Febs J., 282, 2015
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1GC8
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![BU of 1gc8 by Molmil](/molmil-images/mine/1gc8) | THE CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS 3-ISOPROPYLMALATE DEHYDROGENASE MUTATED AT 172TH FROM ALA TO PHE | 分子名称: | 3-ISOPROPYLMALATE DEHYDROGENASE | 著者 | Qu, C, Akanuma, S, Tanaka, N, Moriyama, H, Oshima, T. | 登録日 | 2000-07-27 | 公開日 | 2000-09-27 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Design, X-ray crystallography, molecular modelling and thermal stability studies of mutant enzymes at site 172 of 3-isopropylmalate dehydrogenase from Thermus thermophilus. Acta Crystallogr.,Sect.D, 57, 2001
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7F4B
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![BU of 7f4b by Molmil](/molmil-images/mine/7f4b) | The crystal structure of the immature apo-enzyme of homoserine dehydrogenase from the hyperthermophilic archaeon Sulfurisphaera tokodaii. | 分子名称: | MAGNESIUM ION, homoserine dehydrogenase | 著者 | Kurihara, E, Kubota, T, Watanabe, K, Ogata, K, Kaneko, R, Oshima, T, Yoshimune, K, Goto, M. | 登録日 | 2021-06-18 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Conformational changes in the catalytic region are responsible for heat-induced activation of hyperthermophilic homoserine dehydrogenase. Commun Biol, 5, 2022
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3WSO
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![BU of 3wso by Molmil](/molmil-images/mine/3wso) | Crystal structure of the Skp1-FBG3 complex | 分子名称: | F-box only protein 44, S-phase kinase-associated protein 1 | 著者 | Kumanomidou, T, Nishio, K, Takagi, K, Nakagawa, T, Suzuki, A, Yamane, T, Tokunaga, F, Iwai, K, Murakami, A, Yoshida, Y, Tanaka, K, Mizushima, T. | 登録日 | 2014-03-18 | 公開日 | 2015-03-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The Structural Differences between a Glycoprotein Specific F-Box Protein Fbs1 and Its Homologous Protein FBG3 Plos One, 10, 2015
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7F4C
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![BU of 7f4c by Molmil](/molmil-images/mine/7f4c) | The crystal structure of the immature holo-enzyme of homoserine dehydrogenase complexed with NADP and 1,4-butandiol from the hyperthermophilic archaeon Sulfurisphaera tokodaii. | 分子名称: | 1,4-BUTANEDIOL, Homoserine dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Ogata, K, Kaneko, R, Kubota, T, Watanabe, K, Kurihara, E, Oshima, T, Yoshimune, K, Goto, M. | 登録日 | 2021-06-18 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Conformational changes in the catalytic region are responsible for heat-induced activation of hyperthermophilic homoserine dehydrogenase. Commun Biol, 5, 2022
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5WYA
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![BU of 5wya by Molmil](/molmil-images/mine/5wya) | Structure of amino acid racemase, 2.65 A | 分子名称: | (2S,3S)-3-methyl-2-[[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]pentanoic acid, DIMETHYL SULFOXIDE, Isoleucine 2-epimerase | 著者 | Sakuraba, H, Mutaguchi, Y, Hayashi, J, Ohshima, T. | 登録日 | 2017-01-11 | 公開日 | 2017-04-19 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Crystal structure of the novel amino-acid racemase isoleucine 2-epimerase from Lactobacillus buchneri. Acta Crystallogr D Struct Biol, 73, 2017
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1G2U
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![BU of 1g2u by Molmil](/molmil-images/mine/1g2u) | THE STRUCTURE OF THE MUTANT, A172V, OF 3-ISOPROPYLMALATE DEHYDROGENASE FROM THERMUS THERMOPHILUS HB8 : ITS THERMOSTABILITY AND STRUCTURE. | 分子名称: | 3-ISOPROPYLMALATE DEHYDROGENASE | 著者 | Qu, C, Akanuma, S, Tanaka, N, Moriyama, H, Oshima, T. | 登録日 | 2000-10-21 | 公開日 | 2000-11-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Design, X-ray crystallography, molecular modelling and thermal stability studies of mutant enzymes at site 172 of 3-isopropylmalate dehydrogenase from Thermus thermophilus. Acta Crystallogr.,Sect.D, 57, 2001
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1GC9
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![BU of 1gc9 by Molmil](/molmil-images/mine/1gc9) | THE CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS 3-ISOPROPYLMALATE DEHYDROGENASE MUTATED AT 172TH FROM ALA TO GLY | 分子名称: | 3-ISOPROPYLMALATE DEHYDROGENASE | 著者 | Qu, C, Akanuma, S, Tanaka, N, Moriyama, H, Oshima, T. | 登録日 | 2000-07-28 | 公開日 | 2000-09-27 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Design, X-ray crystallography, molecular modelling and thermal stability studies of mutant enzymes at site 172 of 3-isopropylmalate dehydrogenase from Thermus thermophilus. Acta Crystallogr.,Sect.D, 57, 2001
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3W20
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![BU of 3w20 by Molmil](/molmil-images/mine/3w20) | Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase from Burkholderia ambifaria AMMD | 分子名称: | Putative uncharacterized protein, ZINC ION | 著者 | Qin, H.M, Miyakawa, T, Jia, M.Z, Nakamura, A, Ohtsuka, J, Xue, Y.L, Kawashima, T, Kasahara, T, Hibi, M, Ogawa, J, Tanokura, M. | 登録日 | 2012-11-26 | 公開日 | 2013-07-17 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase from Burkholderia ambifaria AMMD Plos One, 8, 2013
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