2H42
| Crystal structure of PDE5 in complex with sildenafil | 分子名称: | 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, MAGNESIUM ION, ZINC ION, ... | 著者 | Wang, H, Ke, H. | 登録日 | 2006-05-23 | 公開日 | 2006-06-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Multiple Conformations of Phosphodiesterase-5: Implications for enzyme function and drug development J.Biol.Chem., 281, 2006
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2H44
| Crystal structure of PDE5A1 in complex with icarisid II | 分子名称: | 5,7-DIHYDROXY-2-(4-METHOXYPHENYL)-8-(3-METHYLBUTYL)-4-OXO-4H-CHROMEN-3-YL 6-DEOXY-ALPHA-L-MANNOPYRANOSIDE, MAGNESIUM ION, ZINC ION, ... | 著者 | Wang, H, Ke, H. | 登録日 | 2006-05-23 | 公開日 | 2006-06-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Multiple Conformations of Phosphodiesterase-5: Implications for enzyme function and drug development J.Biol.Chem., 281, 2006
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4V7O
| Proteasome Activator Complex | 分子名称: | Proteasome activator BLM10, Proteasome component C1, Proteasome component C11, ... | 著者 | Hill, C.P, Whitby, F.G. | 登録日 | 2009-12-22 | 公開日 | 2014-07-09 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.005 Å) | 主引用文献 | Structure of a Blm10 complex reveals common mechanisms for proteasome binding and gate opening. Mol.Cell, 37, 2010
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6AU1
| Structure of the PgaB (BpsB) glycoside hydrolase domain from Bordetella bronchiseptica | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Putative hemin storage protein, ... | 著者 | Little, D.J, Bamford, N.C, Howell, P.L. | 登録日 | 2017-08-30 | 公開日 | 2018-04-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | PgaB orthologues contain a glycoside hydrolase domain that cleaves deacetylated poly-beta (1,6)-N-acetylglucosamine and can disrupt bacterial biofilms. PLoS Pathog., 14, 2018
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4WLR
| Crystal Structure of mUCH37-hRPN13 CTD-hUb complex | 分子名称: | Polyubiquitin-B, Proteasomal ubiquitin receptor ADRM1, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | 著者 | Hemmis, C.W, Hill, C.P, VanderLinden, R, Whitby, F.G. | 登録日 | 2014-10-07 | 公開日 | 2015-03-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase. Mol.Cell, 57, 2015
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4WLP
| Crystal structure of UCH37-NFRKB Inhibited Deubiquitylating Complex | 分子名称: | Nuclear factor related to kappa-B-binding protein, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | 著者 | Hemmis, C.W, Hill, C.P, VanderLinden, R, Whitby, F.G. | 登録日 | 2014-10-07 | 公開日 | 2015-03-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.102 Å) | 主引用文献 | Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase. Mol.Cell, 57, 2015
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4WLQ
| Crystal structure of mUCH37-hRPN13 CTD complex | 分子名称: | Proteasomal ubiquitin receptor ADRM1, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | 著者 | Hemmis, C.W, Hill, C.P, VanderLinden, R, Whitby, F.G. | 登録日 | 2014-10-07 | 公開日 | 2015-03-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase. Mol.Cell, 57, 2015
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1RCW
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2Q4K
| Ensemble refinement of the protein crystal structure of gene product from Homo sapiens Hs.433573 | 分子名称: | Uncharacterized protein C11orf68 | 著者 | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2007-05-31 | 公開日 | 2007-06-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Ensemble refinement of protein crystal structures: validation and application. Structure, 15, 2007
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6WJA
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2GON
| Xray Structure of Gag133-278 | 分子名称: | CITRATE ANION, Capsid protein p24 (CA) | 著者 | Kelly, B.N. | 登録日 | 2006-04-13 | 公開日 | 2006-09-26 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Implications for Viral Capsid Assembly from Crystal Structures of HIV-1 Gag 1-278 and CAN 133-278. Biochemistry, 45, 2006
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4G59
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2GOL
| Xray Structure of Gag278 | 分子名称: | Capsid protein p24 (CA), Matrix protein p17 (MA), SULFATE ION | 著者 | Kelly, B.N. | 登録日 | 2006-04-13 | 公開日 | 2006-09-26 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Implications for Viral Capsid Assembly from Crystal Structures of HIV-1 Gag 1-278 and CAN 133-278. Biochemistry, 45, 2006
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2NNW
| Alternative conformations of Nop56/58-fibrillarin complex and implication for induced-fit assenly of box C/D RNPs | 分子名称: | Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase, NOP5/NOP56 related protein | 著者 | Oruganti, S, Zhang, Y, Terns, R, Terns, M.P, Li, H. | 登録日 | 2006-10-24 | 公開日 | 2007-08-21 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Alternative Conformations of the Archaeal Nop56/58-Fibrillarin Complex Imply Flexibility in Box C/D RNPs. J.Mol.Biol., 371, 2007
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1Z7Q
| Crystal structure of the 20s proteasome from yeast in complex with the proteasome activator PA26 from Trypanosome brucei at 3.2 angstroms resolution | 分子名称: | Potential proteasome component C5, Proteasome component C1, Proteasome component C11, ... | 著者 | Forster, A, Whitby, F.G, Hill, C.P. | 登録日 | 2005-03-26 | 公開日 | 2005-08-09 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | The 1.9 A structure of a proteasome-11S activator complex and implications for proteasome-PAN/PA700 interactions. Mol.Cell, 18, 2005
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1ZTP
| X-ray structure of gene product from homo sapiens Hs.433573 | 分子名称: | Basophilic leukemia expressed protein BLES03 | 著者 | Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Allard, S.T.M, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2005-05-27 | 公開日 | 2005-06-14 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The structure at 2.5 A resolution of human basophilic leukemia-expressed protein BLES03. Acta Crystallogr.,Sect.F, 61, 2005
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7TNC
| M13F/G116F Pseudomonas aeruginosa azurin | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Azurin, CHLORIDE ION, ... | 著者 | Liu, Y, Lu, Y. | 登録日 | 2022-01-20 | 公開日 | 2023-01-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Structural Basis for the Effects of Phenylalanine on Tuning the Reduction Potential of Type 1 Copper in Azurin. Inorg.Chem., 62, 2023
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7U2F
| G116F Pseudomonas aeruginosa azurin | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Azurin, COPPER (II) ION | 著者 | Liu, Y, Lu, Y. | 登録日 | 2022-02-23 | 公開日 | 2023-03-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Basis for the Effects of Phenylalanine on Tuning the Reduction Potential of Type 1 Copper in Azurin. Inorg.Chem., 62, 2023
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3T5S
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3UO1
| Structure of a monoclonal antibody complexed with its MHC-I antigen | 分子名称: | ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ... | 著者 | Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K. | 登録日 | 2011-11-16 | 公開日 | 2012-07-25 | 最終更新日 | 2012-08-01 | 実験手法 | X-RAY DIFFRACTION (1.641 Å) | 主引用文献 | The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J.Immunol., 189, 2012
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3UYR
| Structure of a monoclonal antibody complexed with its MHC-I antigen | 分子名称: | 1,2-ETHANEDIOL, H-2 class I histocompatibility antigen, L-D alpha chain, ... | 著者 | Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K. | 登録日 | 2011-12-06 | 公開日 | 2012-07-25 | 最終更新日 | 2012-08-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J.Immunol., 189, 2012
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3V4U
| Structure of a monoclonal antibody complexed with its MHC-I antigen | 分子名称: | ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ... | 著者 | Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K. | 登録日 | 2011-12-15 | 公開日 | 2012-07-25 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J.Immunol., 189, 2012
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3B2R
| Crystal Structure of PDE5A1 catalytic domain in complex with Vardenafil | 分子名称: | 2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE, cGMP-specific 3',5'-cyclic phosphodiesterase | 著者 | Huanchen, W, Mengchun, Y, Howard, R, Sharron, H.F, Hengming, K. | 登録日 | 2007-10-19 | 公開日 | 2008-05-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Conformational variations of both phosphodiesterase-5 and inhibitors provide the structural basis for the physiological effects of vardenafil and sildenafil. Mol.Pharmacol., 73, 2008
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5VEQ
| MOUSE KYNURENINE AMINOTRANSFERASE III, RE-REFINEMENT OF THE PDB STRUCTURE 3E2Y | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Wlodawer, A, Dauter, Z, Minor, W, Stanfield, R, Porebski, P, Jaskolski, M, Pozharski, E, Weichenberger, C.X, Rupp, B. | 登録日 | 2017-04-05 | 公開日 | 2017-11-29 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Detect, correct, retract: How to manage incorrect structural models. FEBS J., 285, 2018
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1O06
| Crystal structure of the Vps27p Ubiquitin Interacting Motif (UIM) | 分子名称: | Vacuolar protein sorting-associated protein VPS27, ZINC ION | 著者 | Fisher, R.D, Wang, B, Alam, S.L, Higginson, D.S, Rich, R, Myszka, D, Sundquist, W.I, Hill, C.P. | 登録日 | 2003-02-20 | 公開日 | 2003-07-22 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure and ubiquitin binding of the ubiquitin-interacting motif. J.Biol.Chem., 278, 2003
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