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2H42
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BU of 2h42 by Molmil
Crystal structure of PDE5 in complex with sildenafil
分子名称: 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, MAGNESIUM ION, ZINC ION, ...
著者Wang, H, Ke, H.
登録日2006-05-23
公開日2006-06-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Multiple Conformations of Phosphodiesterase-5: Implications for enzyme function and drug development
J.Biol.Chem., 281, 2006
2H44
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BU of 2h44 by Molmil
Crystal structure of PDE5A1 in complex with icarisid II
分子名称: 5,7-DIHYDROXY-2-(4-METHOXYPHENYL)-8-(3-METHYLBUTYL)-4-OXO-4H-CHROMEN-3-YL 6-DEOXY-ALPHA-L-MANNOPYRANOSIDE, MAGNESIUM ION, ZINC ION, ...
著者Wang, H, Ke, H.
登録日2006-05-23
公開日2006-06-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Multiple Conformations of Phosphodiesterase-5: Implications for enzyme function and drug development
J.Biol.Chem., 281, 2006
4V7O
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BU of 4v7o by Molmil
Proteasome Activator Complex
分子名称: Proteasome activator BLM10, Proteasome component C1, Proteasome component C11, ...
著者Hill, C.P, Whitby, F.G.
登録日2009-12-22
公開日2014-07-09
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.005 Å)
主引用文献Structure of a Blm10 complex reveals common mechanisms for proteasome binding and gate opening.
Mol.Cell, 37, 2010
6AU1
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BU of 6au1 by Molmil
Structure of the PgaB (BpsB) glycoside hydrolase domain from Bordetella bronchiseptica
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Putative hemin storage protein, ...
著者Little, D.J, Bamford, N.C, Howell, P.L.
登録日2017-08-30
公開日2018-04-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献PgaB orthologues contain a glycoside hydrolase domain that cleaves deacetylated poly-beta (1,6)-N-acetylglucosamine and can disrupt bacterial biofilms.
PLoS Pathog., 14, 2018
4WLR
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BU of 4wlr by Molmil
Crystal Structure of mUCH37-hRPN13 CTD-hUb complex
分子名称: Polyubiquitin-B, Proteasomal ubiquitin receptor ADRM1, Ubiquitin carboxyl-terminal hydrolase isozyme L5
著者Hemmis, C.W, Hill, C.P, VanderLinden, R, Whitby, F.G.
登録日2014-10-07
公開日2015-03-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase.
Mol.Cell, 57, 2015
4WLP
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BU of 4wlp by Molmil
Crystal structure of UCH37-NFRKB Inhibited Deubiquitylating Complex
分子名称: Nuclear factor related to kappa-B-binding protein, Ubiquitin carboxyl-terminal hydrolase isozyme L5
著者Hemmis, C.W, Hill, C.P, VanderLinden, R, Whitby, F.G.
登録日2014-10-07
公開日2015-03-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.102 Å)
主引用文献Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase.
Mol.Cell, 57, 2015
4WLQ
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BU of 4wlq by Molmil
Crystal structure of mUCH37-hRPN13 CTD complex
分子名称: Proteasomal ubiquitin receptor ADRM1, Ubiquitin carboxyl-terminal hydrolase isozyme L5
著者Hemmis, C.W, Hill, C.P, VanderLinden, R, Whitby, F.G.
登録日2014-10-07
公開日2015-03-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase.
Mol.Cell, 57, 2015
1RCW
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BU of 1rcw by Molmil
Crystal structure of CT610 from Chlamydia trachomatis
分子名称: CT610, FE (III) ION
著者Schwarzenbacher, R, Liddington, R.C.
登録日2003-11-04
公開日2004-05-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the Chlamydia protein CADD reveals a redox enzyme that modulates host cell apoptosis.
J.Biol.Chem., 279, 2004
2Q4K
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BU of 2q4k by Molmil
Ensemble refinement of the protein crystal structure of gene product from Homo sapiens Hs.433573
分子名称: Uncharacterized protein C11orf68
著者Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
登録日2007-05-31
公開日2007-06-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Ensemble refinement of protein crystal structures: validation and application.
Structure, 15, 2007
6WJA
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BU of 6wja by Molmil
UDP-GlcNAc C4-epimerase mutant S121A/Y146F from Pseudomonas protegens in complex with UDP-GalNAc
分子名称: NAD-dependent epimerase/dehydratase family protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE
著者Marmont, L.S, Pfoh, R, Howell, P.L.
登録日2020-04-13
公開日2020-07-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.094 Å)
主引用文献PelX is a UDP-N-acetylglucosamine C4-epimerase involved in Pel polysaccharide-dependent biofilm formation.
J.Biol.Chem., 295, 2020
2GON
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BU of 2gon by Molmil
Xray Structure of Gag133-278
分子名称: CITRATE ANION, Capsid protein p24 (CA)
著者Kelly, B.N.
登録日2006-04-13
公開日2006-09-26
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Implications for Viral Capsid Assembly from Crystal Structures of HIV-1 Gag 1-278 and CAN 133-278.
Biochemistry, 45, 2006
4G59
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BU of 4g59 by Molmil
Crystal structure of the murine cytomegalovirus MHC-I homolog m152 with ligand RAE-1 gamma
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, M152 protein, Retinoic acid early-inducible protein 1-gamma
著者Wang, R, Natarajan, K, Margulies, D.H.
登録日2012-07-17
公開日2012-12-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structural basis of mouse cytomegalovirus m152/gp40 interaction with RAE1gamma reveals a paradigm for MHC/MHC interaction in immune evasion.
Proc.Natl.Acad.Sci.USA, 109, 2012
2GOL
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BU of 2gol by Molmil
Xray Structure of Gag278
分子名称: Capsid protein p24 (CA), Matrix protein p17 (MA), SULFATE ION
著者Kelly, B.N.
登録日2006-04-13
公開日2006-09-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Implications for Viral Capsid Assembly from Crystal Structures of HIV-1 Gag 1-278 and CAN 133-278.
Biochemistry, 45, 2006
2NNW
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BU of 2nnw by Molmil
Alternative conformations of Nop56/58-fibrillarin complex and implication for induced-fit assenly of box C/D RNPs
分子名称: Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase, NOP5/NOP56 related protein
著者Oruganti, S, Zhang, Y, Terns, R, Terns, M.P, Li, H.
登録日2006-10-24
公開日2007-08-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Alternative Conformations of the Archaeal Nop56/58-Fibrillarin Complex Imply Flexibility in Box C/D RNPs.
J.Mol.Biol., 371, 2007
1Z7Q
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BU of 1z7q by Molmil
Crystal structure of the 20s proteasome from yeast in complex with the proteasome activator PA26 from Trypanosome brucei at 3.2 angstroms resolution
分子名称: Potential proteasome component C5, Proteasome component C1, Proteasome component C11, ...
著者Forster, A, Whitby, F.G, Hill, C.P.
登録日2005-03-26
公開日2005-08-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献The 1.9 A structure of a proteasome-11S activator complex and implications for proteasome-PAN/PA700 interactions.
Mol.Cell, 18, 2005
1ZTP
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BU of 1ztp by Molmil
X-ray structure of gene product from homo sapiens Hs.433573
分子名称: Basophilic leukemia expressed protein BLES03
著者Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Allard, S.T.M, Center for Eukaryotic Structural Genomics (CESG)
登録日2005-05-27
公開日2005-06-14
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure at 2.5 A resolution of human basophilic leukemia-expressed protein BLES03.
Acta Crystallogr.,Sect.F, 61, 2005
7TNC
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BU of 7tnc by Molmil
M13F/G116F Pseudomonas aeruginosa azurin
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Azurin, CHLORIDE ION, ...
著者Liu, Y, Lu, Y.
登録日2022-01-20
公開日2023-01-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Structural Basis for the Effects of Phenylalanine on Tuning the Reduction Potential of Type 1 Copper in Azurin.
Inorg.Chem., 62, 2023
7U2F
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BU of 7u2f by Molmil
G116F Pseudomonas aeruginosa azurin
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Azurin, COPPER (II) ION
著者Liu, Y, Lu, Y.
登録日2022-02-23
公開日2023-03-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for the Effects of Phenylalanine on Tuning the Reduction Potential of Type 1 Copper in Azurin.
Inorg.Chem., 62, 2023
3T5S
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BU of 3t5s by Molmil
Structure of macrophage migration inhibitory factor from Giardia lamblia
分子名称: CHLORIDE ION, Macrophage migration inhibitory factor, SULFATE ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-07-28
公開日2011-08-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a macrophage migration inhibitory factor from Giardia lamblia.
J.Struct.Funct.Genom., 14, 2013
3UO1
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BU of 3uo1 by Molmil
Structure of a monoclonal antibody complexed with its MHC-I antigen
分子名称: ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ...
著者Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K.
登録日2011-11-16
公開日2012-07-25
最終更新日2012-08-01
実験手法X-RAY DIFFRACTION (1.641 Å)
主引用文献The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
3UYR
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BU of 3uyr by Molmil
Structure of a monoclonal antibody complexed with its MHC-I antigen
分子名称: 1,2-ETHANEDIOL, H-2 class I histocompatibility antigen, L-D alpha chain, ...
著者Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K.
登録日2011-12-06
公開日2012-07-25
最終更新日2012-08-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
3V4U
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BU of 3v4u by Molmil
Structure of a monoclonal antibody complexed with its MHC-I antigen
分子名称: ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ...
著者Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K.
登録日2011-12-15
公開日2012-07-25
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
3B2R
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BU of 3b2r by Molmil
Crystal Structure of PDE5A1 catalytic domain in complex with Vardenafil
分子名称: 2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE, cGMP-specific 3',5'-cyclic phosphodiesterase
著者Huanchen, W, Mengchun, Y, Howard, R, Sharron, H.F, Hengming, K.
登録日2007-10-19
公開日2008-05-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Conformational variations of both phosphodiesterase-5 and inhibitors provide the structural basis for the physiological effects of vardenafil and sildenafil.
Mol.Pharmacol., 73, 2008
5VEQ
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BU of 5veq by Molmil
MOUSE KYNURENINE AMINOTRANSFERASE III, RE-REFINEMENT OF THE PDB STRUCTURE 3E2Y
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ...
著者Wlodawer, A, Dauter, Z, Minor, W, Stanfield, R, Porebski, P, Jaskolski, M, Pozharski, E, Weichenberger, C.X, Rupp, B.
登録日2017-04-05
公開日2017-11-29
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Detect, correct, retract: How to manage incorrect structural models.
FEBS J., 285, 2018
1O06
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BU of 1o06 by Molmil
Crystal structure of the Vps27p Ubiquitin Interacting Motif (UIM)
分子名称: Vacuolar protein sorting-associated protein VPS27, ZINC ION
著者Fisher, R.D, Wang, B, Alam, S.L, Higginson, D.S, Rich, R, Myszka, D, Sundquist, W.I, Hill, C.P.
登録日2003-02-20
公開日2003-07-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure and ubiquitin binding of the ubiquitin-interacting motif.
J.Biol.Chem., 278, 2003

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