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7VRB
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BU of 7vrb by Molmil
Structure of the Human BRG1/SS18 complex
分子名称: SMARCA4 protein,Protein SSXT
著者Cheng, Y, Chen, F, Zhou, H, Long, J.
登録日2021-10-22
公開日2022-05-25
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.389 Å)
主引用文献Phase transition and remodeling complex assembly are important for SS18-SSX oncogenic activity in synovial sarcomas.
Nat Commun, 13, 2022
5YEW
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BU of 5yew by Molmil
Structural basis for GTP hydrolysis and conformational change of mitofusin 1 in mediating mitochondrial fusion
分子名称: BERYLLIUM TRIFLUORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Yan, L, Qi, Y, Huang, X, Yu, C.
登録日2017-09-20
公開日2018-01-31
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for GTP hydrolysis and conformational change of MFN1 in mediating membrane fusion
Nat. Struct. Mol. Biol., 25, 2018
5YWO
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BU of 5ywo by Molmil
Structure of JEV-2F2 Fab complex
分子名称: 2F2 heavy chain, 2F2 light chain, JEV E protein, ...
著者Qiu, X, Lei, Y.F, Yang, P, Gao, Q, Wang, N, Cao, L, Yuan, S, Wang, X, Xu, Z.K, Rao, Z.
登録日2017-11-29
公開日2018-03-21
最終更新日2018-09-12
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies
Nat Microbiol, 3, 2018
5YWP
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BU of 5ywp by Molmil
JEV-2H4 Fab complex
分子名称: 2H4 heavy chain, 2H4 light chain, JEV E protein, ...
著者Qiu, X.D, Lei, Y.F, Yang, P, Gao, Q, WANG, N, Cao, L, Yuan, S, Wang, X.X, Xu, Z.K, Rao, Z.H.
登録日2017-11-29
公開日2018-05-02
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies
Nat Microbiol, 3, 2018
5YWF
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BU of 5ywf by Molmil
Crystal structure of 2H4 Fab
分子名称: 2H4 heavy chain, 2H4 light chain
著者Qiu, X, Lei, Y, Yang, P, Gao, Q, Wang, N, Cao, L, Wang, X, Xu, Z.K, Rao, Z.
登録日2017-11-29
公開日2018-03-21
実験手法X-RAY DIFFRACTION (2.206 Å)
主引用文献Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies
Nat Microbiol, 3, 2018
2KQT
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BU of 2kqt by Molmil
Solid-state NMR structure of the M2 transmembrane peptide of the influenza A virus in DMPC lipid bilayers bound to deuterated amantadine
分子名称: (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine, M2 protein
著者Cady, S.D, Schmidt-Rohr, K, Wang, J, Soto, C.S, DeGrado, W.F, Hong, M.
登録日2009-11-18
公開日2010-02-09
最終更新日2024-05-08
実験手法SOLID-STATE NMR
主引用文献Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers
Nature, 463, 2010
7VQQ
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BU of 7vqq by Molmil
Cryo-EM structure of amyloid fibril formed by FUS low complexity domain
分子名称: fusion protein of mCerulean and FUS LCD
著者Sun, Y.P, Xia, W.C, Liu, C.
登録日2021-10-20
公開日2021-12-22
最終更新日2022-02-23
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Molecular structure of an amyloid fibril formed by FUS low-complexity domain.
Iscience, 25, 2022
7V6Q
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BU of 7v6q by Molmil
Crystal structure of sNASP-ASF1A-H3.1-H4 complex
分子名称: GLYCEROL, Histone H3.1, Histone H4, ...
著者Liu, C.P, Xu, R.M.
登録日2021-08-20
公開日2021-12-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Distinct histone H3-H4 binding modes of sNASP reveal the basis for cooperation and competition of histone chaperones.
Genes Dev., 35, 2021
7V6P
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BU of 7v6p by Molmil
Crystal structure of human sNASP TPR domain
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Liu, C.P, Xu, R.M.
登録日2021-08-20
公開日2021-12-29
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Distinct histone H3-H4 binding modes of sNASP reveal the basis for cooperation and competition of histone chaperones.
Genes Dev., 35, 2021
8JNK
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BU of 8jnk by Molmil
Crystal structure of human ALKBH3 bound to ssDNA through active site crosslink
分子名称: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, DNA, MANGANESE (II) ION, ...
著者Zhang, L.
登録日2023-06-06
公開日2024-01-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献The Molecular Basis of Human ALKBH3 Mediated RNA N 1 -methyladenosine (m 1 A) Demethylation.
Angew.Chem.Int.Ed.Engl., 63, 2024
8JNR
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BU of 8jnr by Molmil
Crystal structure of human ALKBH3 bound to 3mC containing ssDNA through distal crosslink
分子名称: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, DNA, MANGANESE (II) ION, ...
著者Zhang, L.
登録日2023-06-06
公開日2024-01-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.66 Å)
主引用文献The Molecular Basis of Human ALKBH3 Mediated RNA N 1 -methyladenosine (m 1 A) Demethylation.
Angew.Chem.Int.Ed.Engl., 63, 2024
8JKK
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BU of 8jkk by Molmil
Crystal Structure of the dioxygenase CcTet from Coprinopsis cinerea bound to 12bp 5-methylcytosine (5mC) containing duplex DNA
分子名称: 2OGFeDO JBP1/TET oxygenase domain-containing protein, DNA (5'-D(P*CP*GP*AP*TP*CP*(5CM)P*GP*CP*TP*AP*CP*G)-3'), DNA (5'-D(P*CP*GP*TP*AP*GP*CP*TP*GP*AP*TP*CP*G)-3'), ...
著者Zhang, L, Zhang, L.
登録日2023-06-01
公開日2024-03-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular basis of an atypical dsDNA 5mC/6mA bifunctional dioxygenase CcTet from Coprinopsis cinerea in catalyzing dsDNA 5mC demethylation.
Nucleic Acids Res., 52, 2024
7ELG
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BU of 7elg by Molmil
LC3B modificated with a covalent probe
分子名称: 2-methylidene-5-thiophen-2-yl-cyclohexane-1,3-dione, Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION
著者Fan, S, Wan, W.
登録日2021-04-10
公開日2021-10-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein.
Angew.Chem.Int.Ed.Engl., 60, 2021
7VPN
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BU of 7vpn by Molmil
Crystal Structure of the dioxygenase CcTet from Coprinopsis cinereain in complex with Mn(II) and N-Oxalylglycine
分子名称: CcTet molecule, MANGANESE (II) ION, N-OXALYLGLYCINE
著者Mu, Y.J, Zhang, L, Zhang, L.
登録日2021-10-17
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A fungal dioxygenase CcTet serves as a eukaryotic 6mA demethylase on duplex DNA.
Nat.Chem.Biol., 18, 2022
7W5P
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BU of 7w5p by Molmil
Crystal Structure of the dioxygenase CcTet from Coprinopsis cinereain bound to 12bp N6-methyldeoxyadenine (6mA) containing duplex DNA
分子名称: CcTet, DNA, DNA (12-MER), ...
著者Mu, Y.J, Zhang, L, Zhang, L.
登録日2021-11-30
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A fungal dioxygenase CcTet serves as a eukaryotic 6mA demethylase on duplex DNA.
Nat.Chem.Biol., 18, 2022
5TEB
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BU of 5teb by Molmil
Crystal Structure of the TIR domain from the Arabidopsis Thaliana disease resistance protein RPP1
分子名称: Recognition of Peronospora parasitica 1
著者Bentham, A.R, Zhang, X, Croll, T, Williams, S, Kobe, B.
登録日2016-09-20
公開日2017-02-01
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.796 Å)
主引用文献Multiple functional self-association interfaces in plant TIR domains.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VXO
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BU of 5vxo by Molmil
Crystal Structure Analysis of human CLYBL in complex with propionyl-CoA
分子名称: 1,2-ETHANEDIOL, Citrate lyase subunit beta-like protein, mitochondrial, ...
著者Shen, H.
登録日2017-05-23
公開日2017-11-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.266 Å)
主引用文献The Human Knockout Gene CLYBL Connects Itaconate to Vitamin B12.
Cell, 171, 2017
5VXC
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BU of 5vxc by Molmil
Crystal Structure Analysis of human CLYBL in complex with free CoASH
分子名称: COENZYME A, Citrate lyase subunit beta-like protein, mitochondrial, ...
著者Shen, H.
登録日2017-05-23
公開日2017-11-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.872 Å)
主引用文献The Human Knockout Gene CLYBL Connects Itaconate to Vitamin B12.
Cell, 171, 2017
5VXS
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BU of 5vxs by Molmil
Crystal Structure Analysis of human CLYBL in apo form
分子名称: CITRIC ACID, Citrate lyase subunit beta-like protein, mitochondrial
著者Shen, H.
登録日2017-05-24
公開日2017-11-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.954 Å)
主引用文献The Human Knockout Gene CLYBL Connects Itaconate to Vitamin B12.
Cell, 171, 2017
7XH6
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BU of 7xh6 by Molmil
Crystal structure of CBP bromodomain liganded with CCS1477
分子名称: (6S)-1-[3,4-bis(fluoranyl)phenyl]-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(4-methoxycyclohexyl)benzimidazol-2-yl]piperidin-2-one, CREB-binding protein, DIMETHYL SULFOXIDE, ...
著者Xu, H, Xiang, Q, Wang, C, Zhang, C, Luo, G, Wu, X, Zhang, Y, Xu, Y.
登録日2022-04-07
公開日2022-07-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural insights revealed by the cocrystal structure of CCS1477 in complex with CBP bromodomain
Biochem.Biophys.Res.Commun., 623, 2022
7XHE
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BU of 7xhe by Molmil
Crystal structure of CBP bromodomain liganded with CCS151
分子名称: (6S)-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(3R)-1-methylsulfonylpyrrolidin-3-yl]benzimidazol-2-yl]-1-(3-fluoranyl-4-methoxy-phenyl)piperidin-2-one, 1,2-ETHANEDIOL, CREB-binding protein
著者Xu, H, Xiang, Q, Wang, C, Zhang, C, Luo, G, Wu, X, Zhang, Y, Xu, Y.
登録日2022-04-08
公開日2022-07-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Structural insights revealed by the cocrystal structure of CCS1477 in complex with CBP bromodomain
Biochem.Biophys.Res.Commun., 623, 2022
7XI0
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BU of 7xi0 by Molmil
Crystal structure of CBP bromodomain liganded with CCS150
分子名称: (6S)-1-(3-chloranyl-4-methoxy-phenyl)-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(3R)-1-methylsulfonylpyrrolidin-3-yl]benzimidazol-2-yl]piperidin-2-one, CREB-binding protein, GLYCEROL
著者Xu, H, Xiang, Q, Wang, C, Zhang, C, Luo, G, Wu, X, Zhang, Y, Xu, Y.
登録日2022-04-11
公開日2022-07-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Structural insights revealed by the cocrystal structure of CCS1477 in complex with CBP bromodomain
Biochem.Biophys.Res.Commun., 623, 2022
7VS2
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BU of 7vs2 by Molmil
secreted fungal effector protein MoErs1
分子名称: MoErs1
著者Wang, F.F, Xing, W.M.
登録日2021-10-25
公開日2023-08-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Targeting Magnaporthe oryzae effector MoErs1 and host papain-like protease OsRD21 interaction to combat rice blast.
Nat.Plants, 2024
5GNT
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BU of 5gnt by Molmil
BDLP-like folding of Mitofusin 1
分子名称: GUANOSINE-5'-DIPHOSPHATE, Mitofusin-1
著者Yan, L, Yu, C, Ming, Z, Rao, Z, Lou, Z, Hu, J.
登録日2016-07-24
公開日2016-11-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.665 Å)
主引用文献the structure of mini-MFN1 in complex with GDP
To Be Published
3NYL
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BU of 3nyl by Molmil
The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain
分子名称: Amyloid beta (A4) protein (Peptidase nexin-II, Alzheimer disease), isoform CRA_b
著者Ha, Y, Hu, J, Lee, S, Liu, X, Wang, Y.
登録日2010-07-15
公開日2011-07-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain.
Mol.Cell, 15, 2004

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