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7U97
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SAAV pH 4.0 capsid structure
分子名称: Capsid protein
著者Mietzsch, M, McKenna, R.
登録日2022-03-10
公開日2022-04-13
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.66 Å)
主引用文献Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
J.Virol., 96, 2022
7U95
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SAAV pH 6.0 capsid structure
分子名称: Capsid protein
著者Mietzsch, M, McKenna, R.
登録日2022-03-10
公開日2022-04-13
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
J.Virol., 96, 2022
7U96
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SAAV pH 5.5 capsid structure
分子名称: Capsid protein
著者Mietzsch, M, McKenna, R.
登録日2022-03-10
公開日2022-04-13
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.14 Å)
主引用文献Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
J.Virol., 96, 2022
7U94
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SAAV pH 7.4 capsid structure
分子名称: Capsid protein
著者Mietzsch, M, McKenna, R.
登録日2022-03-10
公開日2022-04-13
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
J.Virol., 96, 2022
8TU2
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The Capsid of Rat Bocavirus
分子名称: VP2
著者Velez, M, Mietzsch, M, McKenna, R.
登録日2023-08-15
公開日2023-08-30
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (2.52 Å)
主引用文献Structural Characterization of Canine Minute Virus, Rat and Porcine Bocavirus.
Viruses, 15, 2023
8TU1
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The Capsid of Porcine Bocavirus 1
分子名称: VP2
著者Velez, M, Mietzsch, M, McKenna, R.
登録日2023-08-15
公開日2023-08-30
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (2.31 Å)
主引用文献Structural Characterization of Canine Minute Virus, Rat and Porcine Bocavirus.
Viruses, 15, 2023
8TU0
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The Capsid of Canine Minute Virus
分子名称: VP2
著者Velez, M, Mietzsch, M, McKenna, R.
登録日2023-08-15
公開日2023-08-30
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献Structural Characterization of Canine Minute Virus, Rat and Porcine Bocavirus.
Viruses, 15, 2023
8P8X
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Crystal structure of a pathogenic mutant variant of human mitochodnrial PheRS
分子名称: PHENYLALANINE, Phenylalanine--tRNA ligase, mitochondrial
著者Chen, W, Kuhle, B.
登録日2023-06-03
公開日2023-08-16
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Clinical and molecular characterization of novel FARS2 variants causing neonatal mitochondrial disease.
Mol.Genet.Metab., 140, 2023
5KNN
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Evolutionary gain of alanine mischarging to non-cognate tRNAs with a G4:U69 base pair
分子名称: '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, Alanine--tRNA ligase, cytoplasmic
著者Sun, L, He, W, Yang, X.-L.
登録日2016-06-28
公開日2016-09-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Evolutionary Gain of Alanine Mischarging to Noncognate tRNAs with a G4:U69 Base Pair.
J.Am.Chem.Soc., 138, 2016
7QA4
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Crystal structure of stabilized H3N2 A/Hong Kong/1/1968 Hemagglutinin at 2.2 Angstrom
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Milder, F.J, Langedijk, J.P.M.
登録日2021-11-16
公開日2022-02-02
最終更新日2022-03-30
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Universal stabilization of the influenza hemagglutinin by structure-based redesign of the pH switch regions.
Proc.Natl.Acad.Sci.USA, 119, 2022
5N5K
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Human catalytic MMP-12 in complex with 5-(1,2-dithiolan-3-yl)-N-(3-hydroxypropyl)pentanamide
分子名称: 5-[(3~{S})-1,2-dithiolan-3-yl]-~{N}-(3-oxidanylpropyl)pentanamide, ACETOHYDROXAMIC ACID, CALCIUM ION, ...
著者Calderone, V.
登録日2017-02-14
公開日2017-11-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX).
J. Med. Chem., 60, 2017
5N5J
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Human MMP12 in complex with 3-(5-(1,2-dithiolan-3-yl)pentanamido)propane-1-sulfonate
分子名称: 3-[5-[(3~{S})-1,2-dithiolan-3-yl]pentanoylamino]propane-1-sulfonic acid, ACETOHYDROXAMIC ACID, CALCIUM ION, ...
著者Calderone, V.
登録日2017-02-14
公開日2017-11-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX).
J. Med. Chem., 60, 2017
4GUQ
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Structure of mutS139F p73 DNA binding domain complexed with 20BP DNA response element
分子名称: DNA (5'-D(P*GP*AP*AP*CP*AP*TP*GP*TP*TP*C)-3'), Tumor protein p73, ZINC ION
著者Ethayathulla, A.S, Nguyen, H.T, Viadiu, H.
登録日2012-08-29
公開日2013-08-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code.
Nucleic Acids Res., 41, 2013
4LWV
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The 2.3A Crystal Structure of Humanized Xenopus MDM2 with RO5545353
分子名称: (2S,3R,4R,5R)-N-(4-carbamoyl-2-methoxyphenyl)-2'-chloro-4-(3-chloro-2-fluorophenyl)-2-(2,2-dimethylpropyl)-5'-oxo-4',5'-dihydrospiro[pyrrolidine-3,6'-thieno[3,2-b]pyrrole]-5-carboxamide, E3 ubiquitin-protein ligase Mdm2, SULFATE ION
著者Graves, B.J, Lukacs, C, Janson, C.A.
登録日2013-07-28
公開日2014-07-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Discovery of Potent and Orally Active p53-MDM2 Inhibitors RO5353 and RO2468 for Potential Clinical Development.
ACS MED.CHEM.LETT., 5, 2014
7F3Z
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Double mutant Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS-K1, C59R+S108N) complexed with Trimethoprim (TOP), NADPH and dUMP
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase, GLYCEROL, ...
著者Vanichtanankul, J, Tanramluk, D, Chitnumsub, P, Yuvaniyama, J, Yuthavong, Y.
登録日2021-06-17
公開日2021-09-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献MANORAA: A machine learning platform to guide protein-ligand design by anchors and influential distances.
Structure, 30, 2022
6SQJ
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BU of 6sqj by Molmil
Crystal structure of glycoprotein D of Equine Herpesvirus Type 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein D, ...
著者Kremling, V, Loll, B, Azab, W, Osterrieder, N, Dahmani, I, Chiantia, P, Wahl, M.
登録日2019-09-04
公開日2020-09-30
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.245 Å)
主引用文献Crystal structures of glycoprotein D of equine alphaherpesviruses reveal potential binding sites to the entry receptor MHC-I.
Front Microbiol, 14, 2023
2W2X
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Complex of Rac2 and PLCg2 spPH Domain
分子名称: 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-2, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, ...
著者Opaleye, O, Bunney, T.D, Roe, S.M, Pearl, L.H.
登録日2008-11-04
公開日2009-05-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2.
Mol.Cell, 34, 2009
2W2W
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PLCg2 Split Pleckstrin Homology (PH) Domain
分子名称: 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-2
著者Opaleye, O, Bunney, T.D, Roe, S.M, Pearl, L.H.
登録日2008-11-04
公開日2009-05-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2.
Mol.Cell, 34, 2009
2W2V
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Rac2 (G12V) in complex with GTPgS
分子名称: GUANOSINE-5'-TRIPHOSPHATE, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2
著者Opaleye, O, Bunney, T.D, Roe, S.M, Pearl, L.H.
登録日2008-11-04
公開日2009-05-05
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2.
Mol.Cell, 34, 2009
2W2T
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Rac2 (G12V) in complex with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2
著者Opaleye, O, Bunney, T.D, Roe, S.M, Pearl, L.H.
登録日2008-11-04
公開日2009-05-05
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2.
Mol.Cell, 34, 2009
3GK8
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BU of 3gk8 by Molmil
X-ray crystal structure of the Fab from MAb 14, mouse antibody against Canine Parvovirus
分子名称: Fab 14 Heavy Chain, Fab 14 Light Chain
著者Hafenstein, S, Bowman, V, Sun, T, Nelson, C, Palermo, L, Chipman, P, Battisti, A, Parrish, C.
登録日2009-03-10
公開日2009-06-16
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural comparison of different antibodies interacting with parvovirus capsids.
J.Virol., 83, 2009
7NB1
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Crystal structure of human choline alpha in complex with an inhibitor
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-(6-aminopurin-9-yl)-~{N}-[4-(trifluoromethylsulfonyl)phenyl]cyclohexane-1-carboxamide, Choline kinase alpha
著者Casale, E, Fasolini, M.
登録日2021-01-25
公開日2021-10-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Identification of unprecedented ATP-competitive choline kinase inhibitors.
Bioorg.Med.Chem.Lett., 51, 2021
7NB2
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Crystal structure of human choline alpha in complex with an inhibitor
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-(6-azanyl-2-chloranyl-purin-9-yl)-~{N}-(4-methyl-1,3-thiazol-2-yl)cyclohexane-1-carboxamide, Choline kinase alpha, ...
著者Casale, E, Fasolini, M.
登録日2021-01-25
公開日2021-10-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Identification of unprecedented ATP-competitive choline kinase inhibitors.
Bioorg.Med.Chem.Lett., 51, 2021
7NB3
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Crystal structure of human choline alpha in complex with an inhibitor
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-(6-azanyl-2-pyridin-4-yl-purin-9-yl)-~{N}-(3-methoxyphenyl)cyclohexane-1-carboxamide, Choline kinase alpha, ...
著者Casale, E, Fasolini, M.
登録日2021-01-25
公開日2021-10-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification of unprecedented ATP-competitive choline kinase inhibitors.
Bioorg.Med.Chem.Lett., 51, 2021
6V1Z
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genome-containing AAVrh.39 particles
分子名称: Capsid protein VP1, DNA (5'-D(*CP*A)-3')
著者Mietzsch, M, Agbandje-McKenna, M.
登録日2019-11-21
公開日2019-12-11
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Comparative Analysis of the Capsid Structures of AAVrh.10, AAVrh.39, and AAV8.
J.Virol., 94, 2020

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