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4R3B
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BU of 4r3b by Molmil
Crystal structure of SHV-1 b-lactamase in complex with 6b-(hydroxymethyl)penicillanic acid sulfone PSR-283A
分子名称: Beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, N-[(1E)-2-formyl-3-hydroxyprop-1-en-1-yl]-3-[(S)-sulfino]-D-valine
著者Rodkey, E.A, van den Akker, F.
登録日2014-08-14
公開日2015-01-21
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.366 Å)
主引用文献Detecting a Quasi-stable Imine Species on the Reaction Pathway of SHV-1 beta-Lactamase and 6 beta-(Hydroxymethyl)penicillanic Acid Sulfone.
Biochemistry, 54, 2015
3G7L
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BU of 3g7l by Molmil
Chromodomain of Chp1 in complex with Histone H3K9me3 peptide
分子名称: ACETIC ACID, Chromo domain-containing protein 1, Histone H3.1/H3.2, ...
著者Schalch, T, Joshua-Tor, L.
登録日2009-02-10
公開日2009-04-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献High-affinity binding of Chp1 chromodomain to K9 methylated histone H3 is required to establish centromeric heterochromatin
Mol.Cell, 34, 2009
4R8M
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BU of 4r8m by Molmil
Human SIRT2 crystal structure in complex with BHJH-TM1
分子名称: BHJH-TM1 peptide, NAD-dependent protein deacetylase sirtuin-2, ZINC ION, ...
著者Teng, Y.B, Hao, Q, Lin, H.N, Jing, H.
登録日2014-09-02
公開日2015-03-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Efficient Demyristoylase Activity of SIRT2 Revealed by Kinetic and Structural Studies
Sci Rep, 5, 2015
7UVR
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BU of 7uvr by Molmil
Crystal structure of human ClpP protease in complex with TR-65
分子名称: 3-{[(10R)-4-[(4-chlorophenyl)methyl]-5-oxo-1,2,4,5,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-7(6H)-yl]methyl}benzonitrile, ATP-dependent Clp protease proteolytic subunit, mitochondrial
著者Mabanglo, M.F, Houry, W.A.
登録日2022-05-02
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome.
Structure, 31, 2023
7UIB
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BU of 7uib by Molmil
Crystal structure of BoNT/E receptor binding domain in complex with SV2, VHH, and sialic acid
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-beta-neuraminic acid, ...
著者Liu, Z, Jin, R, Chen, P.
登録日2022-03-29
公開日2023-04-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.
Nat Commun, 14, 2023
7UIA
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BU of 7uia by Molmil
Crystal structure of BoNT/E receptor binding domain in complex with SV2 and VHH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Liu, Z, Jin, R, Chen, P.
登録日2022-03-28
公開日2023-04-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.
Nat Commun, 14, 2023
7UIE
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BU of 7uie by Molmil
Crystal structure of HcE-JLE-G6
分子名称: Botulinum neurotoxin E heavy chain, JLE-G6
著者Jin, R, Lam, K.
登録日2022-03-29
公開日2023-04-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.23 Å)
主引用文献Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.
Nat Commun, 14, 2023
3DNV
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BU of 3dnv by Molmil
MDT Protein
分子名称: DNA (5'-D(*DAP*DCP*DTP*DAP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DTP*DAP*DG)-3'), HTH-type transcriptional regulator hipB, Protein hipA, ...
著者schumacher, M.A.
登録日2008-07-02
公開日2009-01-27
最終更新日2023-04-05
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
7XJX
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BU of 7xjx by Molmil
The cryo-EM structure of Fe3+ induced alpha-syn fibril.
分子名称: Alpha-synuclein
著者Zhao, Q.Y, Tao, Y.Q, Zhao, K, Tao, Y.Q, Li, D.
登録日2022-04-18
公開日2023-01-18
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural Insights of Fe3+ Induced alpha-synuclein Fibrillation in Parkinson' Disease
J.Mol.Biol., 435, 2023
7X27
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BU of 7x27 by Molmil
MERS-CoV spike complex
分子名称: Spike glycoprotein
著者Zeng, J.W, Zhang, S.Y, Wang, X.W.
登録日2022-02-25
公開日2023-03-22
実験手法ELECTRON MICROSCOPY (2.49 Å)
主引用文献cryo-EM structures of a human neutralizing antibody bound to MERS-CoV spike glycoprotein
To Be Published
1PME
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BU of 1pme by Molmil
STRUCTURE OF PENTA MUTANT HUMAN ERK2 MAP KINASE COMPLEXED WITH A SPECIFIC INHIBITOR OF HUMAN P38 MAP KINASE
分子名称: 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE, ERK2, SULFATE ION
著者Xie, X.
登録日1998-06-08
公開日1999-06-08
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A single amino acid substitution makes ERK2 susceptible to pyridinyl imidazole inhibitors of p38 MAP kinase.
Protein Sci., 7, 1998
3FBR
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BU of 3fbr by Molmil
structure of HipA-amppnp-peptide
分子名称: PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Serine/threonine-protein kinase toxin HipA, peptide of EF-Tu
著者Schumacher, M.A.
登録日2008-11-19
公開日2009-02-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
3DJ4
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BU of 3dj4 by Molmil
Crystal Structure of GlmU from Mycobacterium tuberculosis in complex with URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE.
分子名称: Bifunctional protein glmU, COBALT (II) ION, MAGNESIUM ION, ...
著者Verma, S.K, Prakash, B.
登録日2008-06-22
公開日2009-05-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献PknB-mediated phosphorylation of a novel substrate, N-acetylglucosamine-1-phosphate uridyltransferase, modulates its acetyltransferase activity.
J.Mol.Biol., 386, 2009
4RUD
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BU of 4rud by Molmil
Crystal structure of a three finger toxin
分子名称: Three-finger toxin 3b, ZINC ION
著者Jobichen, C, Sivaraman, J.
登録日2014-11-18
公開日2016-05-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Fulditoxin, representing a new class of dimeric snake toxins, defines novel pharmacology at nicotinic ACh receptors.
Br.J.Pharmacol., 177, 2020
3VZE
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BU of 3vze by Molmil
Crystal structure of human pancreatic secretory protein ZG16p with alpha1,3-mannobiose
分子名称: CHLORIDE ION, Zymogen granule membrane protein 16, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose
著者Kanagawa, M, Yamaguchi, Y.
登録日2012-10-11
公開日2013-10-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis for Multiple Sugar Recognition of Jacalin-related Human ZG16p Lectin
J.Biol.Chem., 289, 2014
4KS5
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BU of 4ks5 by Molmil
Influenza neuraminidase in complex with antiviral compound (3S,4R,5R)-4-(acetylamino)-3-[4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl]-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
分子名称: (3S,4R,5R)-4-(acetylamino)-3-[4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl]-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, Neuraminidase
著者Kerry, P.S, Russell, R.J.M.
登録日2013-05-17
公開日2013-10-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.699 Å)
主引用文献Structural basis for a class of nanomolar influenza A neuraminidase inhibitors.
Sci Rep, 3, 2013
2MQ1
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BU of 2mq1 by Molmil
Phosphotyrosine binding domain
分子名称: E3 ubiquitin-protein ligase Hakai, ZINC ION
著者Mukherjee, M, Jing-Song, F, Sivaraman, J.
登録日2014-06-11
公開日2014-08-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Dimeric switch of Hakai-truncated monomers during substrate recognition: insights from solution studies and NMR structure.
J.Biol.Chem., 289, 2014
4LRK
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BU of 4lrk by Molmil
Bacterial Effector NleH2 Kinase Domain
分子名称: Effector NleH2
著者Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2013-07-19
公開日2014-01-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.274 Å)
主引用文献NleH defines a new family of bacterial effector kinases.
Structure, 22, 2014
3VY6
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BU of 3vy6 by Molmil
Crystal structure of human pancreatic secretory protein ZG16p with laminaribiose
分子名称: CHLORIDE ION, Zymogen granule membrane protein 16, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose
著者Kanagawa, M, Yamaguchi, Y.
登録日2012-09-21
公開日2013-09-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Multiple Sugar Recognition of Jacalin-related Human ZG16p Lectin
J.Biol.Chem., 289, 2014
3VZF
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BU of 3vzf by Molmil
Crystal structure of human pancreatic secretory protein ZG16p with methyl alpha-D-mannopyranoside
分子名称: CHLORIDE ION, Zymogen granule membrane protein 16, methyl alpha-D-mannopyranoside
著者Kanagawa, M, Yamaguchi, Y.
登録日2012-10-11
公開日2013-10-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for Multiple Sugar Recognition of Jacalin-related Human ZG16p Lectin
J.Biol.Chem., 289, 2014
3VY7
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BU of 3vy7 by Molmil
Crystal structure of human pancreatic secretory protein ZG16p with O-(alpha-D-mannosyl)-L-serine
分子名称: CHLORIDE ION, SERINE, Zymogen granule membrane protein 16, ...
著者Kanagawa, M, Yamaguchi, Y.
登録日2012-09-21
公開日2013-09-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structural Basis for Multiple Sugar Recognition of Jacalin-related Human ZG16p Lectin
J.Biol.Chem., 289, 2014
3VZG
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BU of 3vzg by Molmil
Crystal structure of human pancreatic secretory protein ZG16p with O-(alpha-D-mannosyl)-L-threonine
分子名称: CHLORIDE ION, THREONINE, Zymogen granule membrane protein 16, ...
著者Kanagawa, M, Yamaguchi, Y.
登録日2012-10-11
公開日2013-10-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis for Multiple Sugar Recognition of Jacalin-related Human ZG16p Lectin
J.Biol.Chem., 289, 2014
3WOG
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BU of 3wog by Molmil
Crystal structure plant lectin in complex with ligand
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, CALCIUM ION, ...
著者Nagae, M, Yamaguchi, Y.
登録日2013-12-26
公開日2014-04-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Phytohemagglutinin from Phaseolus vulgaris (PHA-E) displays a novel glycan recognition mode using a common legume lectin fold
Glycobiology, 24, 2014
2HZC
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BU of 2hzc by Molmil
Crystal structure of the N-terminal RRM of the U2AF large subunit
分子名称: HEXAETHYLENE GLYCOL, Splicing factor U2AF 65 kDa subunit, ZINC ION
著者Thickman, K.R, Sickmier, E.A, Kielkopf, C.L.
登録日2006-08-08
公開日2006-08-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Alternative Conformations at the RNA-binding Surface of the N-terminal U2AF(65) RNA Recognition Motif.
J.Mol.Biol., 366, 2007
2NYA
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BU of 2nya by Molmil
Crystal structure of the periplasmic nitrate reductase (NAP) from Escherichia coli
分子名称: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, IRON/SULFUR CLUSTER, MOLYBDENUM(VI) ION, ...
著者Jepson, B.J.N, Richardson, D.J, Hemmings, A.M.
登録日2006-11-20
公開日2006-12-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Spectropotentiometric and structural analysis of the periplasmic nitrate reductase from Escherichia coli
J.Biol.Chem., 282, 2007

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