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1YTS
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A LIGAND-INDUCED CONFORMATIONAL CHANGE IN THE YERSINIA PROTEIN TYROSINE PHOSPHATASE
分子名称: SULFATE ION, YERSINIA PROTEIN TYROSINE PHOSPHATASE
著者Schubert, H.L, Stuckey, J.A, Fauman, E.B, Dixon, J.E, Saper, M.A.
登録日1995-04-07
公開日1995-07-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A ligand-induced conformational change in the Yersinia protein tyrosine phosphatase.
Protein Sci., 4, 1995
7WI0
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BU of 7wi0 by Molmil
SARS-CoV-2 Omicron variant spike in complex with three human neutralizing antibodies
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c1437_light_IGLV1-40_IGLJ1, IG c934_light_IGKV1-5_IGKJ1, ...
著者Zheng, Q, Li, S, Sun, H, Zheng, Z, Wang, S.
登録日2022-01-01
公開日2022-06-22
実験手法ELECTRON MICROSCOPY (3.82 Å)
主引用文献Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron.
Cell Rep, 39, 2022
7WHZ
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BU of 7whz by Molmil
SARS-CoV-2 spike protein in complex with three human neutralizing antibodies
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c1437_light_IGLV1-40_IGLJ1, IG c934_light_IGKV1-5_IGKJ1, ...
著者Zheng, Q, Li, S, Sun, H, Zheng, Z, Wang, S.
登録日2022-01-01
公開日2022-06-22
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron.
Cell Rep, 39, 2022
6JWZ
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BU of 6jwz by Molmil
Crystal structure of Plasmodium falciparum HPPK-DHPS S436F/A437G/A613S triple mutant with SDX-DHP
分子名称: 4-[(2-azanyl-4-oxidanylidene-7,8-dihydro-3~{H}-pteridin-6-yl)methylamino]-~{N}-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide, 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase, ACETATE ION, ...
著者Chitnumsub, P, Jaruwat, A, Yuthavong, Y.
登録日2019-04-21
公開日2020-02-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献The structure of Plasmodium falciparum hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase reveals the basis of sulfa resistance.
Febs J., 287, 2020
6KCL
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BU of 6kcl by Molmil
Crystal structure of Plasmodium falciparum HPPK-DHPS A437G/K540E with pterin and p-hydroxybenzoate
分子名称: 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase, ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Chitnumsub, P, Jaruwat, A, Yuthavong, Y.
登録日2019-06-28
公開日2020-02-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structure of Plasmodium falciparum hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase reveals the basis of sulfa resistance.
Febs J., 287, 2020
6KCK
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BU of 6kck by Molmil
Crystal structure of Plasmodium falciparum HPPK-DHPS wild type with pterin and p-hydroxybenzoate
分子名称: 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase, ACETATE ION, CALCIUM ION, ...
著者Chitnumsub, P, Jaruwat, A, Yuthavong, Y.
登録日2019-06-28
公開日2020-02-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure of Plasmodium falciparum hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase reveals the basis of sulfa resistance.
Febs J., 287, 2020
7F3N
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BU of 7f3n by Molmil
Structure of PopP2 in apo form
分子名称: Type III effector protein popp2
著者Xia, Y, Zhang, Z.M.
登録日2021-06-16
公開日2021-11-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.351856 Å)
主引用文献Secondary-structure switch regulates the substrate binding of a YopJ family acetyltransferase.
Nat Commun, 12, 2021
7BWJ
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BU of 7bwj by Molmil
crystal structure of SARS-CoV-2 antibody with RBD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody heavy chain, ...
著者Wang, X, Ge, J.
登録日2020-04-14
公開日2020-06-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Human neutralizing antibodies elicited by SARS-CoV-2 infection.
Nature, 584, 2020
7WJ6
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BU of 7wj6 by Molmil
Crystal Structure of the Kinase Domain of a Class III Lanthipeptide Synthetase CurKC
分子名称: MAGNESIUM ION, Serine/threonine protein kinase
著者Huang, S, Wang, H.
登録日2022-01-05
公開日2022-11-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Discovery of a Unique Structural Motif in Lanthipeptide Synthetases for Substrate Binding and Interdomain Interactions.
Angew.Chem.Int.Ed.Engl., 61, 2022
7WJ7
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BU of 7wj7 by Molmil
Crystal Structure of the Kinase Domain with Adenosine of a Class III Lanthipeptide Synthetase CurKC
分子名称: 2-(6-AMINO-OCTAHYDRO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, Serine/threonine protein kinase
著者Huang, S, Wang, H.
登録日2022-01-05
公開日2022-11-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Discovery of a Unique Structural Motif in Lanthipeptide Synthetases for Substrate Binding and Interdomain Interactions.
Angew.Chem.Int.Ed.Engl., 61, 2022
5YH0
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BU of 5yh0 by Molmil
The structure of DrFam20C1
分子名称: DrFam20C1
著者Zhang, H, Xiao, J.
登録日2017-09-27
公開日2018-04-11
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Structure and evolution of the Fam20 kinases
Nat Commun, 9, 2018
5YJ5
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BU of 5yj5 by Molmil
structure for wildtype Human prion protein (M129)
分子名称: Major prion protein
著者Zheng, Z, Lin, D.
登録日2017-10-08
公開日2018-04-11
最終更新日2019-04-24
実験手法SOLUTION NMR
主引用文献Structural basis for the complete resistance of the human prion protein mutant G127V to prion disease.
Sci Rep, 8, 2018
5YH2
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BU of 5yh2 by Molmil
The structure of DrFam20C1 and hFam20A complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Family with sequence similarity 20, member Ca, ...
著者Zhang, H, Xiao, J.
登録日2017-09-27
公開日2018-04-11
最終更新日2018-04-25
実験手法X-RAY DIFFRACTION (3.55 Å)
主引用文献Structure and evolution of the Fam20 kinases
Nat Commun, 9, 2018
5YMY
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BU of 5ymy by Molmil
The structure of the complex between Rpn13 and K48-diUb
分子名称: Proteasomal ubiquitin receptor ADRM1, Ubiquitin
著者Liu, Z, Dong, X, Gong, Z, Yi, H.W, Liu, K, Yang, J, Zhang, W.P, Tang, C.
登録日2017-10-22
公開日2019-03-13
最終更新日2019-04-24
実験手法SOLUTION NMR
主引用文献Structural basis for the recognition of K48-linked Ub chain by proteasomal receptor Rpn13.
Cell Discov, 5, 2019
5YJ4
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BU of 5yj4 by Molmil
structure for the protective mutant G127V of Human prion protein
分子名称: Major prion protein
著者Zheng, Z, Lin, D.
登録日2017-10-07
公開日2018-04-11
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural basis for the complete resistance of the human prion protein mutant G127V to prion disease.
Sci Rep, 8, 2018
5Z7A
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BU of 5z7a by Molmil
Crystal structure of NDP52 SKICH region
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Calcium-binding and coiled-coil domain-containing protein 2, GLYCEROL, ...
著者Pan, L.F, Fu, T, Liu, J.P, Xie, X.Q.
登録日2018-01-27
公開日2019-01-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Mechanistic insights into the interactions of NAP1 with the SKICH domains of NDP52 and TAX1BP1
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7XML
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BU of 7xml by Molmil
Cryo-EM structure of PEIP-Bs_enolase complex
分子名称: Enolase, MAGNESIUM ION, Putative gene 60 protein
著者Li, S, Zhang, K.
登録日2022-04-26
公開日2022-07-27
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Bacteriophage protein PEIP is a potent Bacillus subtilis enolase inhibitor.
Cell Rep, 40, 2022
5ZAT
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BU of 5zat by Molmil
Crystal structure of 5-carboxylcytosine containing decamer dsDNA
分子名称: DNA (5'-D(*CP*CP*AP*GP*(CAC)P*GP*CP*TP*GP*G)-3')
著者Fu, T.R, Zhang, L.
登録日2018-02-08
公開日2019-02-13
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.06 Å)
主引用文献Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine.
Chem Sci, 10, 2019
7CJT
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BU of 7cjt by Molmil
Crystal Structure of SETDB1 Tudor domain in complexed with (R,R)-59
分子名称: 2-[[(3~{R},5~{R})-1-methyl-5-(4-phenylmethoxyphenyl)piperidin-3-yl]amino]-3-prop-2-enyl-5~{H}-pyrrolo[3,2-d]pyrimidin-4-one, Histone-lysine N-methyltransferase SETDB1
著者Guo, Y.P, Liang, X, Mao, X, Wu, C, Luyi, H, Yang, S.
登録日2020-07-13
公開日2021-04-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.474 Å)
主引用文献Structure-Guided Discovery of a Potent and Selective Cell-Active Inhibitor of SETDB1 Tudor Domain.
Angew.Chem.Int.Ed.Engl., 60, 2021
7CAJ
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BU of 7caj by Molmil
Crystal structure of SETDB1 Tudor domain in complexed with Compound 2.
分子名称: 3-methyl-2-[[(3R,5R)-1-methyl-5-phenyl-piperidin-3-yl]amino]-5H-pyrrolo[3,2-d]pyrimidin-4-one, Histone-lysine N-methyltransferase SETDB1
著者Guo, Y.P, Liang, X, Xin, M, Luyi, H, Chengyong, W, Yang, S.Y.
登録日2020-06-08
公開日2021-04-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.198 Å)
主引用文献Structure-Guided Discovery of a Potent and Selective Cell-Active Inhibitor of SETDB1 Tudor Domain.
Angew.Chem.Int.Ed.Engl., 60, 2021
7CHO
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BU of 7cho by Molmil
Crystal structure of SARS-CoV-2 antibody P5A-1D2 with RBD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P5A-1D2 heavy chain, ...
著者Wang, X, Zhang, L, Ge, J, Wang, R, Zhang, Q.
登録日2020-07-06
公開日2021-05-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.561 Å)
主引用文献Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2.
Nat Commun, 12, 2021
7CHS
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BU of 7chs by Molmil
Crystal structure of SARS-CoV-2 antibody P22A-1D1 with RBD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P22A-1D1 heavy chain, ...
著者Wang, X, Zhang, L, Ge, J, Wang, R, Zhang, Q.
登録日2020-07-06
公開日2021-05-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2.
Nat Commun, 12, 2021
7CHP
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BU of 7chp by Molmil
Crystal structure of SARS-CoV-2 antibody P5A-3C8 with RBD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P5A-3C8 heavy chain, ...
著者Wang, X, Zhang, L, Ge, J, Wang, R, Zhang, Q.
登録日2020-07-06
公開日2021-05-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.357 Å)
主引用文献Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2.
Nat Commun, 12, 2021
5ZTK
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BU of 5ztk by Molmil
Synchrotron structure of light-driven chloride pump having an NTQ motif
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ...
著者Yun, J.H, Park, J.H, Park, S.Y, Lee, W.
登録日2018-05-04
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Non-cryogenic structure of a chloride pump provides crucial clues to temperature-dependent channel transport efficiency
J. Biol. Chem., 294, 2019
6KN0
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BU of 6kn0 by Molmil
caspase-1 P20/P10 C285A in complex with human GSDMD-C domain
分子名称: Caspase-1, Gasdermin-D
著者Ding, J, Sun, Q.
登録日2019-08-02
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.793 Å)
主引用文献Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020

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