4FE7
 
 | | structure of xylose-binding transcription activator xylR | | 分子名称: | Xylose operon regulatory protein, alpha-D-xylopyranose | | 著者 | Ni, L, Schumacher, M.A. | | 登録日 | 2012-05-29 | | 公開日 | 2012-12-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structures of the Escherichia coli transcription activator and regulator of diauxie, XylR: an AraC DNA-binding family member with a LacI/GalR ligand-binding domain.
Nucleic Acids Res., 41, 2013
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3NXC
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3M8E
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3M89
 | | Structure of TubZ-GTP-g-S | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, FtsZ/tubulin-related protein | | 著者 | Ni, L, Xu, W, Schumacher, M.A. | | 登録日 | 2010-03-17 | | 公開日 | 2010-07-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | From the Cover: Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition.
Proc.Natl.Acad.Sci.USA, 107, 2010
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1RPW
 | | Crystal Structure Of The Multidrug Binding Protein Qacr Bound To The Diamidine Hexamidine | | 分子名称: | 4,4'[1,6-HEXANEDIYLBIS(OXY)]BISBENZENECARBOXIMIDAMIDE, SULFATE ION, Transcriptional regulator qacR | | 著者 | Murray, D.S, Schumacher, M.A, Brennan, R.G. | | 登録日 | 2003-12-03 | | 公開日 | 2004-06-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structures of QacR-diamidine complexes reveal additional multidrug-binding modes and a novel mechanism of drug charge neutralization.
J.Biol.Chem., 279, 2004
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1RKW
 | | CRYSTAL STRUCTURE OF THE MULTIDRUG BINDING TRANSCRIPTIONAL REPRESSOR QACR BOUND TO PENTAMADINE | | 分子名称: | 1,5-BIS(4-AMIDINOPHENOXY)PENTANE, SULFATE ION, Transcriptional regulator qacR | | 著者 | Murray, D.S, Schumacher, M.A, Brennan, R.G. | | 登録日 | 2003-11-23 | | 公開日 | 2004-06-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Crystal structures of QacR-diamidine complexes reveal additional multidrug-binding modes and a novel mechanism of drug charge neutralization.
J.Biol.Chem., 279, 2004
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2PUB
 | | CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES | | 分子名称: | ADENINE, DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), PURINE REPRESSOR | | 著者 | Schumacher, R.G, Choi, K.Y, Zalkin, H, Brennan, M.A. | | 登録日 | 1997-10-04 | | 公開日 | 1998-05-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices.
Science, 266, 1994
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2PUA
 | | CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES | | 分子名称: | 6-METHYLPURINE, DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), PURINE REPRESSOR | | 著者 | Schumacher, R.G, Choi, K.Y, Zalkin, H, Brennan, M.A. | | 登録日 | 1997-10-04 | | 公開日 | 1998-05-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices.
Science, 266, 1994
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5KBJ
 | | Structure of Rep-DNA complex | | 分子名称: | DNA (32-MER), Replication initiator A, N-terminal | | 著者 | Schumacher, M. | | 登録日 | 2016-06-03 | | 公開日 | 2016-06-29 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | | 主引用文献 | Mechanism of staphylococcal multiresistance plasmid replication origin assembly by the RepA protein.
Proc. Natl. Acad. Sci. U.S.A., 111, 2014
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5TZD
 | | Structure of the WT S. venezulae BldD-(CTD-c-di-GMP)2 assembly intermediate | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein | | 著者 | Schumacher, M. | | 登録日 | 2016-11-21 | | 公開日 | 2017-04-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.749 Å) | | 主引用文献 | The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
Nucleic Acids Res., 45, 2017
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5K58
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5K5A
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5K5O
 | | Structure of AspA-26mer DNA complex | | 分子名称: | AspA, DNA (26-MER) | | 著者 | Schumacher, M. | | 登録日 | 2016-05-23 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages.
Science, 349, 2015
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5K5D
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5K5R
 | | AspA-32mer DNA,crystal form 2 | | 分子名称: | AspA, DNA (32-MER), PHOSPHATE ION | | 著者 | Schumacher, M. | | 登録日 | 2016-05-23 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | | 主引用文献 | Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages.
Science, 349, 2015
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5K5Q
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5K5Z
 | | Structure of pnob8 ParA | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ParA | | 著者 | Schumacher, M. | | 登録日 | 2016-05-24 | | 公開日 | 2016-06-22 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.369 Å) | | 主引用文献 | Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages.
Science, 349, 2015
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5K98
 | | Structure of HipA-HipB-O2-O3 complex | | 分子名称: | Antitoxin HipB, DNA (5'-D(*CP*TP*AP*TP*CP*CP*CP*CP*TP*TP*AP*AP*GP*GP*GP*GP*AP*TP*AP*GP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*CP*TP*AP*TP*CP*CP*CP*CP*TP*TP*AP*AP*GP*GP*GP*GP*AP*TP*AP*G)-3'), ... | | 著者 | Schumacher, M. | | 登録日 | 2016-05-31 | | 公開日 | 2016-06-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.99 Å) | | 主引用文献 | HipBA-promoter structures reveal the basis of heritable multidrug tolerance.
Nature, 524, 2015
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1YM8
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6TZ8
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6TZ7
 | | Crystal Structure of Aspergillus fumigatus Calcineurin A, Calcineurin B, FKBP12 and FK506 (Tacrolimus) | | 分子名称: | 1,2-ETHANEDIOL, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, CALCIUM ION, ... | | 著者 | Fox III, D, Horanyi, P.S. | | 登録日 | 2019-08-10 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents.
Nat Commun, 10, 2019
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5DXL
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8FW0
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8FW3
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8FW8
 | | MtrR from Neisseria gonorrhoeae bound to Progesterone | | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, HTH-type transcriptional regulator MtrR, PHOSPHATE ION, ... | | 著者 | Hooks, G.H, Brennan, R.G. | | 登録日 | 2023-01-20 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Hormonal steroids induce multidrug resistance and stress response genes in Neisseria gonorrhoeae by binding to MtrR.
Nat Commun, 15, 2024
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