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8JD0
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BU of 8jd0 by Molmil
Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of NAM563
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(1-methylpyrazol-4-yl)-7-[[(2~{S})-2-(trifluoromethyl)morpholin-4-yl]methyl]quinoline-2-carboxamide, CHOLESTEROL, ...
著者Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B.
登録日2023-05-12
公開日2023-06-21
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
6KHX
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BU of 6khx by Molmil
Crystal structure of Prx from Akkermansia muciniphila
分子名称: CALCIUM ION, Peroxiredoxin
著者Li, M, Wang, J, Xu, W, Wang, Y, Zhang, M, Wang, M.
登録日2019-07-16
公開日2020-02-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Crystal structure of Akkermansia muciniphila peroxiredoxin reveals a novel regulatory mechanism of typical 2-Cys Prxs by a distinct loop.
Febs Lett., 594, 2020
3QZR
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BU of 3qzr by Molmil
Human enterovirus 71 3C protease mutant E71A in complex with rupintrivir
分子名称: 1,2-ETHANEDIOL, 3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
著者Wang, J, Fan, T, Yao, X, Wu, Z, Guo, L, Lei, X, Wang, J, Wang, M, Jin, Q, Cui, S.
登録日2011-03-07
公開日2011-08-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.039 Å)
主引用文献Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues.
J.Virol., 85, 2011
3QZQ
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BU of 3qzq by Molmil
Human enterovirus 71 3C protease mutant E71D in complex with rupintrivir
分子名称: 3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
著者Wang, J, Fan, T, Yao, X, Wu, Z, Guo, L, Lei, X, Wang, J, Wang, M, Jin, Q, Cui, S.
登録日2011-03-07
公開日2011-08-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7001 Å)
主引用文献Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues.
J.Virol., 85, 2011
3R0F
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BU of 3r0f by Molmil
Human enterovirus 71 3C protease mutant H133G in complex with rupintrivir
分子名称: 1,2-ETHANEDIOL, 3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
著者Wang, J, Fan, T, Yao, X, Wu, Z, Guo, L, Lei, X, Wang, J, Wang, M, Jin, Q, Cui, S.
登録日2011-03-08
公開日2011-08-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.3083 Å)
主引用文献Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues.
J.Virol., 85, 2011
3OSY
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BU of 3osy by Molmil
Human enterovirus 71 3C protease
分子名称: 3C protease
著者Wang, J, Fan, T, Wang, M, Cui, S.
登録日2010-09-10
公開日2011-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9923 Å)
主引用文献Crystal Structure of Human Enterovirus 71 3C Protease.
J.Mol.Biol., 408, 2011
1KVK
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BU of 1kvk by Molmil
The Structure of Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, mevalonate kinase
著者Fu, Z, Wang, M, Potter, D, Mizioko, H.M, Kim, J.J.
登録日2002-01-26
公開日2002-03-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Structure of a Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease
J.Biol.Chem., 277, 2002
4EQ2
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BU of 4eq2 by Molmil
Crystal Structure Analysis of Chicken Interferon Gamma Receptor Alpha Chain
分子名称: Interferon gamma receptor 1
著者Ping, Z, Qi, J, Lu, G, Shi, Y, Wang, X, Gao, G.F, Wang, M.
登録日2012-04-18
公開日2013-04-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Crystal structure of the interferon gamma receptor alpha chain from chicken reveals an undetected extra helix compared with the human counterparts.
J.Interferon Cytokine Res., 34, 2014
5ZTE
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BU of 5zte by Molmil
Crystal structure of PrxA C119S mutant from Arabidopsis thaliana
分子名称: 2-Cys peroxiredoxin BAS1, chloroplastic
著者Yang, Y, Cai, W, Wang, J, Pan, W, Liu, L, Wang, M, Zhang, M.
登録日2018-05-03
公開日2018-10-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of Arabidopsis thaliana peroxiredoxin A C119S mutant.
Acta Crystallogr F Struct Biol Commun, 74, 2018
4EQ3
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BU of 4eq3 by Molmil
Crystal Structure Analysis of Selenomethionine (Se-Met) Substituted Chicken Interferon Gamma Receptor Alpha Chain
分子名称: Interferon gamma receptor 1
著者Ping, Z, Qi, J, Lu, G, Shi, Y, Wang, X, Gao, G.F, Wang, M.
登録日2012-04-18
公開日2013-04-24
最終更新日2014-05-21
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Crystal structure of the interferon gamma receptor alpha chain from chicken reveals an undetected extra helix compared with the human counterparts.
J.Interferon Cytokine Res., 34, 2014
2WFL
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BU of 2wfl by Molmil
Crystal structure of polyneuridine aldehyde esterase
分子名称: POLYNEURIDINE-ALDEHYDE ESTERASE, SULFATE ION
著者Yang, L, Hill, M, Panjikar, S, Wang, M, Stoeckigt, J.
登録日2009-04-08
公開日2009-08-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis and Enzymatic Mechanism of the Biosynthesis of C9- from C10-Monoterpenoid Indole Alkaloids.
Angew.Chem.Int.Ed.Engl., 48, 2009
2WFM
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BU of 2wfm by Molmil
Crystal structure of polyneuridine aldehyde esterase mutant (H244A)
分子名称: POLYNEURIDINE ALDEHYDE ESTERASE
著者Yang, L, Hill, M, Panjikar, S, Wang, M, Stoeckigt, J.
登録日2009-04-08
公開日2010-04-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis and Enzymatic Mechanism of the Biosynthesis of C9- from C10-Monoterpenoid Indole Alkaloids.
Angew.Chem.Int.Ed.Engl., 48, 2009
8GQC
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BU of 8gqc by Molmil
Crystal structure of the SARS-unique domain (SUD) of SARS-CoV-2 (1.35 angstrom resolution)
分子名称: Papain-like protease nsp3
著者Qin, B, Li, Z, Aumonier, S, Wang, M, Cui, S.
登録日2022-08-30
公開日2023-07-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Identification of the SARS-unique domain of SARS-CoV-2 as an antiviral target.
Nat Commun, 14, 2023
4H75
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BU of 4h75 by Molmil
Crystal structure of human Spindlin1 in complex with a histone H3K4(me3) peptide
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Histone H3, ...
著者Yang, N, Wang, W, Wang, Y, Wang, M, Zhao, Q, Rao, Z, Zhu, B, Xu, R.M.
登録日2012-09-20
公開日2012-10-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.098 Å)
主引用文献Distinct mode of methylated lysine-4 of histone H3 recognition by tandem tudor-like domains of Spindlin1.
Proc.Natl.Acad.Sci.USA, 109, 2012
7DK0
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BU of 7dk0 by Molmil
Crystal structure of SARS-CoV-2 Spike RBD in complex with MW05 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MW05 heavy chain, MW05 light chain, ...
著者Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M.
登録日2020-11-22
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.199 Å)
主引用文献Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires Fc gamma RIIB and virus-antibody complex with bivalent interaction.
Commun Biol, 5, 2022
7DJZ
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BU of 7djz by Molmil
Crystal structure of SARS-CoV-2 Spike RBD in complex with MW01 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, MW01 heavy chain, ...
著者Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M.
登録日2020-11-22
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.397 Å)
主引用文献Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires Fc gamma RIIB and virus-antibody complex with bivalent interaction.
Commun Biol, 5, 2022
6KY4
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BU of 6ky4 by Molmil
Crystal structure of Sulfiredoxin from Arabidopsis thaliana
分子名称: ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, Sulfiredoxin, ...
著者Liu, M, Wang, J, Li, X, Li, M, Sylvanno, M.J, Zhang, M, Wang, M.
登録日2019-09-16
公開日2019-10-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The crystal structure of sulfiredoxin from Arabidopsis thaliana revealed a more robust antioxidant mechanism in plants.
Biochem.Biophys.Res.Commun., 520, 2019
8HBL
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BU of 8hbl by Molmil
Crystal structure of the SARS-unique domain (SUD) of SARS-CoV-2 (1.58 angstrom resolution)
分子名称: GLYCEROL, LITHIUM ION, Non-structural protein 3, ...
著者Qin, B, Li, Z, Aumonier, S, Wang, M, Cui, S.
登録日2022-10-29
公開日2023-07-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Identification of the SARS-unique domain of SARS-CoV-2 as an antiviral target.
Nat Commun, 14, 2023
5KWB
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BU of 5kwb by Molmil
Crystal Structure of the Receptor Binding Domain of the Spike Glycoprotein of Human Betacoronavirus HKU1 (HKU1 1A-CTD, 1.9 angstrom, molecular replacement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Spike glycoprotein, ...
著者Guan, H, Wojdyla, J.A, Wang, M, Cui, S.
登録日2016-07-17
公開日2017-06-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Crystal structure of the receptor binding domain of the spike glycoprotein of human betacoronavirus HKU1
Nat Commun, 8, 2017
3EAD
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BU of 3ead by Molmil
Crystal structure of CALX-CBD1
分子名称: CALCIUM ION, GLYCEROL, Na/Ca exchange protein
著者Zheng, L, Wang, M.
登録日2008-08-25
公開日2009-09-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structures of progressive Ca2+ binding states of the Ca2+ sensor Ca2+ binding domain 1 (CBD1) from the CALX Na+/Ca2+ exchanger reveal incremental conformational transitions.
J.Biol.Chem., 285, 2010
5Z3W
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BU of 5z3w by Molmil
Malate dehydrogenase binds silver at C113
分子名称: Malate dehydrogenase, SILVER ION
著者Wang, H, Wang, M, Sun, H.
登録日2018-01-09
公開日2019-01-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Atomic differentiation of silver binding preference in protein targets: Escherichia coli malate dehydrogenase as a paradigm
Chem Sci, 2020
2AKJ
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BU of 2akj by Molmil
Structure of spinach nitrite reductase
分子名称: Ferredoxin--nitrite reductase, chloroplast, IRON/SULFUR CLUSTER, ...
著者Swamy, U, Wang, M, Tripathy, J.N, Kim, S.-K, Hirasawa, M, Knaff, D.B, Allen, J.P.
登録日2005-08-03
公開日2006-01-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Spinach Nitrite Reductase: Implications for Multi-electron Reactions by the Iron-Sulfur:Siroheme Cofactor
Biochemistry, 44, 2005
2PQE
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BU of 2pqe by Molmil
Solution structure of proline-free mutant of staphylococcal nuclease
分子名称: Thermonuclease
著者Shan, L, Tong, Y, Xie, T, Wang, M, Wang, J.
登録日2007-05-01
公開日2007-06-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Restricted backbone conformational and motional flexibilities of loops containing peptidyl-proline bonds dominate the enzyme activity of staphylococcal nuclease.
Biochemistry, 46, 2007
8Q2O
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BU of 8q2o by Molmil
Structure of alginate transporter AlgE from P. aeruginosa PAO1 by using Se-MAG for the the lipid cubic phase crystallization
分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Alginate production protein AlgE, ...
著者Huang, C.-Y, Boland, C, Kaki, S.S, Wang, M, Olieric, V, Caffrey, M.
登録日2023-08-03
公開日2024-05-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Se-MAG Is a Convenient Additive for Experimental Phasing and Structure Determination of Membrane Proteins Crystallised by the Lipid Cubic Phase (In Meso) Method
Crystals, 2023
8Q2P
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BU of 8q2p by Molmil
Structure of the membrane integral lipoprotein N-acyltransferase Lnt from E. coli by using Se-MAG for the the lipid cubic phase crystallization
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, Apolipoprotein N-acyltransferase, ...
著者Huang, C.-Y, Boland, C, Kaki, S.S, Wang, M, Olieric, V, Caffrey, M.
登録日2023-08-03
公開日2024-05-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Se-MAG Is a Convenient Additive for Experimental Phasing and Structure Determination of Membrane Proteins Crystallised by the Lipid Cubic Phase (In Meso) Method
Crystals, 2023

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