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7LN4
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BU of 7ln4 by Molmil
Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (FOM, Class 3)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Pan, M, Yu, Y, Liu, L, Zhao, M.
登録日2021-02-06
公開日2021-09-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Mechanistic insight into substrate processing and allosteric inhibition of human p97.
Nat.Struct.Mol.Biol., 28, 2021
7LN0
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BU of 7ln0 by Molmil
Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and Ub6 (Class 2)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Hexa-ubiquitin, ...
著者Pan, M, Yu, Y, Liu, L, Zhao, M.
登録日2021-02-06
公開日2021-09-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Mechanistic insight into substrate processing and allosteric inhibition of human p97.
Nat.Struct.Mol.Biol., 28, 2021
7LMY
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BU of 7lmy by Molmil
Cryo-EM structure of human p97 in complex with NMS-873 in the presence of ATP, Npl4/Ufd1, and Ub6
分子名称: 3-[3-cyclopentylsulfanyl-5-[[3-methyl-4-(4-methylsulfonylphenyl)phenoxy]methyl]-1,2,4-triazol-4-yl]pyridine, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Pan, M, Yu, Y, Liu, L, Zhao, M.
登録日2021-02-06
公開日2021-09-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Mechanistic insight into substrate processing and allosteric inhibition of human p97.
Nat.Struct.Mol.Biol., 28, 2021
7LN2
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BU of 7ln2 by Molmil
Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (FOM, Class 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Pan, M, Yu, Y, Liu, L, Zhao, M.
登録日2021-02-06
公開日2021-09-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.63 Å)
主引用文献Mechanistic insight into substrate processing and allosteric inhibition of human p97.
Nat.Struct.Mol.Biol., 28, 2021
7LN3
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BU of 7ln3 by Molmil
Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (FOM, Class 2)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Pan, M, Yu, Y, Liu, L, Zhao, M.
登録日2021-02-06
公開日2021-09-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Mechanistic insight into substrate processing and allosteric inhibition of human p97.
Nat.Struct.Mol.Biol., 28, 2021
7LMZ
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BU of 7lmz by Molmil
Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and Ub6 (Class 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Hexa-ubiquitin, ...
著者Pan, M, Yu, Y, Liu, L, Zhao, M.
登録日2021-02-06
公開日2021-09-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Mechanistic insight into substrate processing and allosteric inhibition of human p97.
Nat.Struct.Mol.Biol., 28, 2021
7LN1
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BU of 7ln1 by Molmil
Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and Ub6 (Class 3)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Hexa-ubiquitin, ...
著者Pan, M, Yu, Y, Liu, L, Zhao, M.
登録日2021-02-06
公開日2021-09-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Mechanistic insight into substrate processing and allosteric inhibition of human p97.
Nat.Struct.Mol.Biol., 28, 2021
7LN6
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BU of 7ln6 by Molmil
Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (CHAPSO, Class 2, Open State)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Pan, M, Yu, Y, Liu, L, Zhao, M.
登録日2021-02-06
公開日2021-09-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Mechanistic insight into substrate processing and allosteric inhibition of human p97.
Nat.Struct.Mol.Biol., 28, 2021
3WL8
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BU of 3wl8 by Molmil
Crystal Structure of pOPH S172A with octanoic acid
分子名称: CITRIC ACID, OCTANOIC ACID (CAPRYLIC ACID), Oxidized polyvinyl alcohol hydrolase
著者Yang, Y, Ko, T.P, Li, J.H, Liu, L, Huang, C.H, Chan, H.C, Ren, F.F, Jia, D.X, Wang, A.H.-J, Guo, R.T, Chen, J, Du, G.C.
登録日2013-11-08
公開日2014-09-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insights into enzymatic degradation of oxidized polyvinyl alcohol
Chembiochem, 15, 2014
3WL5
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BU of 3wl5 by Molmil
Crystal structure of pOPH S172C
分子名称: CITRIC ACID, Oxidized polyvinyl alcohol hydrolase
著者Yang, Y, Ko, T.P, Li, J.H, Liu, L, Huang, C.H, Chan, H.C, Ren, F.F, Jia, D.X, Wang, A.H.-J, Guo, R.T, Chen, J, Du, G.C.
登録日2013-11-07
公開日2014-09-24
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insights into enzymatic degradation of oxidized polyvinyl alcohol
Chembiochem, 15, 2014
3WLA
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BU of 3wla by Molmil
Crystal Structure of sOPH Native
分子名称: Oxidized polyvinyl alcohol hydrolase, SULFATE ION
著者Yang, Y, Ko, T.P, Li, J.H, Liu, L, Huang, C.H, Chan, H.C, Ren, F.F, Jia, D.X, Wang, A.H.-J, Guo, R.T, Chen, J, Du, G.C.
登録日2013-11-08
公開日2014-09-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into enzymatic degradation of oxidized polyvinyl alcohol
Chembiochem, 15, 2014
3WL7
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BU of 3wl7 by Molmil
The complex structure of pOPH S172C with ligand, ACA
分子名称: CITRIC ACID, Oxidized polyvinyl alcohol hydrolase, pentane-2,4-dione
著者Yang, Y, Ko, T.P, Li, J.H, Liu, L, Huang, C.H, Chan, H.C, Ren, F.F, Jia, D.X, Wang, A.H.-J, Guo, R.T, Chen, J, Du, G.C.
登録日2013-11-08
公開日2014-09-24
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structural insights into enzymatic degradation of oxidized polyvinyl alcohol
Chembiochem, 15, 2014
8IQ6
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BU of 8iq6 by Molmil
Cryo-EM structure of Latanoprost-bound prostaglandin-F2-alpha receptor-miniGq-Nb35 complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Lv, X, Gao, K, Nie, J, Zhang, X, Zhang, S, Ren, Y, Li, Q, Huang, J, Liu, L, Zhang, X, Sun, X, Zhang, W, Liu, X.
登録日2023-03-15
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structures of human prostaglandin F 2 alpha receptor reveal the mechanism of ligand and G protein selectivity.
Nat Commun, 14, 2023
8IQ4
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BU of 8iq4 by Molmil
Cryo-EM structure of Carboprost-bound prostaglandin-F2-alpha receptor-miniGq-Nb35 complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Lv, X, Gao, K, Nie, J, Zhang, X, Zhang, S, Ren, Y, Li, Q, Huang, J, Liu, L, Zhang, X, Sun, X, Zhang, W, Liu, X.
登録日2023-03-15
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structures of human prostaglandin F 2 alpha receptor reveal the mechanism of ligand and G protein selectivity.
Nat Commun, 14, 2023
5YEI
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BU of 5yei by Molmil
Mechanistic insight into the regulation of Pseudomonas aeruginosa aspartate kinase
分子名称: Aspartokinase, GLYCEROL, LYSINE, ...
著者Li, C, Yang, M, Liu, L, Peng, C, Li, T, He, L, Song, Y, Zhu, Y, Bao, R.
登録日2017-09-17
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Mechanistic insights into the allosteric regulation of Pseudomonas aeruginosa aspartate kinase.
Biochem.J., 475, 2018
5Z9X
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BU of 5z9x by Molmil
Arabidopsis SMALL RNA DEGRADING NUCLEASE 1 in complex with an RNA substrate
分子名称: MAGNESIUM ION, RNA (5'-R(P*GP*CP*CP*CP*AP*UP*UP*AP*G)-3'), SULFATE ION, ...
著者Chen, J, Liu, L, You, C, Gu, J, Ruan, W, Zhang, L, Gan, J, Cao, C, Huang, Y, Chen, X, Ma, J.
登録日2018-02-05
公開日2018-06-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1.
Nat Commun, 9, 2018
5Z9Z
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BU of 5z9z by Molmil
The C-terminal RRM domain of Arabidopsis SMALL RNA DEGRADING NUCLEASE 1 (E329A/E330A/E332A)
分子名称: CITRATE ANION, Small RNA degrading nuclease 1
著者Chen, J, Liu, L, You, C, Gu, J, Ruan, W, Zhang, L, Cao, C, Gan, J, Huang, Y, Chen, X, Ma, J.
登録日2018-02-05
公開日2018-06-27
最終更新日2018-10-03
実験手法X-RAY DIFFRACTION (2.049 Å)
主引用文献Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1.
Nat Commun, 9, 2018
8IEJ
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BU of 8iej by Molmil
RNF20-RNF40/hRad6A-Ub/nucleosome complex
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ...
著者Ai, H, Deng, Z, Sun, M, Du, Y, Pan, M, Liu, L.
登録日2023-02-15
公開日2023-09-06
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A.
Mol.Cell, 83, 2023
8IEG
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BU of 8ieg by Molmil
Bre1(mRBD-RING)/Rad6-Ub/nucleosome complex
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase BRE1, Histone H2A type 1-B/E, ...
著者Ai, H, Deng, Z, Pan, M, Liu, L.
登録日2023-02-15
公開日2023-09-06
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (3.44 Å)
主引用文献Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A.
Mol.Cell, 83, 2023
8KAK
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BU of 8kak by Molmil
Crystal structure of SpyCas9 in complex with sgRNA and 18nt target DNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (26-MER), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
著者Chen, Y, Chen, J, Liu, L.
登録日2023-08-03
公開日2024-06-05
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8KAL
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BU of 8kal by Molmil
Crystal structure of SpyCas9 in complex with sgRNA and 17nt target DNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (25-MER), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
著者Chen, Y, Chen, J, Liu, L.
登録日2023-08-03
公開日2024-06-05
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8KAJ
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BU of 8kaj by Molmil
Crystal structure of SpyCas9-crRNA-tracrRNA complex bound to 16nt target DNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*CP*AP*AP*TP*AP*CP*CP*TP*TP*TP*TP*AP*TP*CP*CP*AP*TP*AP*AP*AP*TP*TP*CP*G)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
著者Chen, Y, Chen, J, Liu, L.
登録日2023-08-03
公開日2024-06-05
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8KAM
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BU of 8kam by Molmil
Crystal structure of SpyCas9 in complex with sgRNA and 16nt target DNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*CP*AP*AP*TP*AP*CP*CP*TP*CP*TP*TP*CP*AP*AP*TP*TP*AP*GP*AP*AP*CP*AP*CP*G)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
著者Chen, Y, Chen, J, Liu, L.
登録日2023-08-03
公開日2024-06-05
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.91 Å)
主引用文献Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8KAG
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BU of 8kag by Molmil
Crystal structure of SpyCas9 in complex with sgRNA and target RNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, RNA (5'-R(*CP*CP*AP*CP*UP*UP*CP*AP*AP*UP*UP*AP*GP*AP*AP*CP*AP*CP*GP*GP*AP*CP*C)-3'), RNA (98-MER)
著者Chen, Y, Chen, J, Liu, L.
登録日2023-08-03
公開日2024-06-05
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.88 Å)
主引用文献Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8KAI
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BU of 8kai by Molmil
Crystal structure of SpyCas9-crRNA-tracrRNA complex bound to 17nt target DNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (25-MER), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
著者Chen, Y, Chen, J, Liu, L.
登録日2023-08-03
公開日2024-06-05
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024

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件を2024-06-12に公開中

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