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5YFI
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BU of 5yfi by Molmil
Crystal structure of the anti-human prostaglandin E receptor EP4 antibody Fab fragment
分子名称: Heavy chain of Fab fragment, Light chain of Fab fragment, ZINC ION
著者Toyoda, Y, Morimoto, K, Suno, R, Horita, S, Iwata, S, Kobayashi, T.
登録日2017-09-21
公開日2018-12-05
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.848 Å)
主引用文献Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface.
Nat. Chem. Biol., 15, 2019
5YHL
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BU of 5yhl by Molmil
Crystal structure of the human prostaglandin E receptor EP4 in complex with Fab and an antagonist Br-derivative
分子名称: 4-[2-[[(2R)-2-(4-bromanylnaphthalen-1-yl)propanoyl]amino]-4-cyano-phenyl]butanoic acid, Heavy chain of Fab fragment, Light chain of Fab fragment, ...
著者Toyoda, Y, Morimoto, K, Suno, R, Horita, S, Iwata, S, Kobayashi, T.
登録日2017-09-28
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface.
Nat. Chem. Biol., 15, 2019
5YWY
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BU of 5ywy by Molmil
Crystal structure of the human prostaglandin E receptor EP4 in complex with Fab and ONO-AE3-208
分子名称: 4-[4-cyano-2-[[(2R)-2-(4-fluoranylnaphthalen-1-yl)propanoyl]amino]phenyl]butanoic acid, Heavy chain of Fab fragment, Light chain of Fab fragment, ...
著者Toyoda, Y, Morimoto, K, Suno, R, Horita, S, Iwata, S, Kobayashi, T.
登録日2017-11-30
公開日2018-12-05
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface.
Nat. Chem. Biol., 15, 2019
2ROM
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BU of 2rom by Molmil
CRYSTAL STRUCTURE OF NITRIC REDUCTASE FROM DENITRIFYING FUNGUS FUSARIUM OXYSPORUM COMPLEX WITH CARBON MONOXIDE
分子名称: CARBON MONOXIDE, CYTOCHROME P450, PROTOPORPHYRIN IX CONTAINING FE
著者Park, S.-Y, Nakagawa, A.
登録日1997-03-24
公開日1997-10-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of nitric oxide reductase from denitrifying fungus Fusarium oxysporum.
Nat.Struct.Biol., 4, 1997
2RSD
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BU of 2rsd by Molmil
Solution structure of the plant homeodomain (PHD) of the E3 SUMO ligase Siz1 from rice
分子名称: E3 SUMO-protein ligase SIZ1, ZINC ION
著者Shindo, H, Tsuchiya, W, Suzuki, R, Yamazaki, T.
登録日2012-01-12
公開日2012-08-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献PHD finger of the SUMO ligase Siz/PIAS family in rice reveals specific binding for methylated histone H3 at lysine 4 and arginine 2
Febs Lett., 586, 2012
8GRT
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BU of 8grt by Molmil
Small Dipeptide Analogues developed by Co-crystal Structure of Stenotrophomonas maltophilia Dipeptidyl Peptidase 7
分子名称: 2-AMINO-3-CYCLOHEXYL-PROPIONIC ACID, Dipeptidyl-peptidase, TYROSINE
著者Yasumitsu, S, Koushi, H, Akihiro, N, Yoshiyuki, Y, Wataru, O, Mizuki, S, Saori, R, Nobutada, T, Anna, M, Keiko, H, Tsuda, Y.
登録日2022-09-02
公開日2023-09-06
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Small Dipeptide Analogues Generated by Co-crystal Structure of Bacterial Dipeptidyl Peptidase 7 to Defeat Stenotrophomonas maltophilia
To Be Published
7Y7D
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BU of 7y7d by Molmil
Structure of the Bacterial Ribosome with human tRNA Asp(Q34) and mRNA(GAU)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2022-06-22
公開日2023-10-25
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7C
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BU of 7y7c by Molmil
Structure of the Bacterial Ribosome with human tRNA Asp(G34) and mRNA(GAU)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2022-06-22
公開日2023-10-25
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.51 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7F
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BU of 7y7f by Molmil
Structure of the Bacterial Ribosome with human tRNA Asp(ManQ34) and mRNA(GAC)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2022-06-22
公開日2023-10-25
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.43 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7E
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BU of 7y7e by Molmil
Structure of the Bacterial Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2022-06-22
公開日2023-10-25
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.41 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7G
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BU of 7y7g by Molmil
Structure of the Bacterial Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2022-06-22
公開日2023-10-25
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.34 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7Y7H
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BU of 7y7h by Molmil
Structure of the Bacterial Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAC)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2022-06-22
公開日2023-10-25
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.51 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
8GZC
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BU of 8gzc by Molmil
Crystal structure of EP300 HAT domain in complex with compound 10
分子名称: (2~{R},4~{R})-4-fluoranyl-1-[1-(4-methoxyphenyl)cyclohexyl]carbonyl-~{N}-(1~{H}-pyrazolo[4,3-b]pyridin-5-yl)pyrrolidine-2-carboxamide, Histone acetyltransferase p300, ZINC ION
著者Takahashi, M, Hanzawa, H.
登録日2022-09-26
公開日2023-01-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of DS-9300: A Highly Potent, Selective, and Once-Daily Oral EP300/CBP Histone Acetyltransferase Inhibitor.
J.Med.Chem., 66, 2023
1F26
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BU of 1f26 by Molmil
CRYSTAL STRUCTURE OF NO COMPLEX OF THR243VAL MUTANTS OF CYTOCHROME P450NOR
分子名称: GLYCEROL, NITRIC OXIDE, NITRIC OXIDE REDUCTASE, ...
著者Shimizu, H, Park, S.-Y.
登録日2000-05-23
公開日2000-11-23
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Mutation effects of a conserved threonine (Thr243) of cytochrome P450nor on its structure and function.
J.Inorg.Biochem., 82, 2000
6FEK
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BU of 6fek by Molmil
Oncogenic point mutation of RET receptor tyrosine kinase
分子名称: ADENOSINE, FORMIC ACID, Proto-oncogene tyrosine-protein kinase receptor Ret
著者McDonald, N.Q, Kohno, T.
登録日2018-01-02
公開日2018-02-28
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A secondary RET mutation in the activation loop conferring resistance to vandetanib.
Nat Commun, 9, 2018
1UKX
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BU of 1ukx by Molmil
Solution structure of the RWD domain of mouse GCN2
分子名称: GCN2 eIF2alpha kinase
著者Nameki, N, Yoneyama, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2003-09-03
公開日2004-08-03
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the RWD domain of the mouse GCN2 protein.
Protein Sci., 13, 2004
1F24
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BU of 1f24 by Molmil
CRYSTAL STRUCTURE OF NO COMPLEX OF THR243ALA MUTANTS OF CYTOCHROME P450NOR
分子名称: GLYCEROL, NITRIC OXIDE, NITRIC OXIDE REDUCTASE, ...
著者Shimizu, H, Park, S.-Y.
登録日2000-05-23
公開日2000-11-23
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Mutation effects of a conserved threonine (Thr243) of cytochrome P450nor on its structure and function.
J.Inorg.Biochem., 82, 2000
1F25
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BU of 1f25 by Molmil
CRYSTAL STRUCTURE OF NO COMPLEX OF THR243ASN MUTANTS OF CYTOCHROME P450NOR
分子名称: GLYCEROL, NITRIC OXIDE, NITRIC OXIDE REDUCTASE, ...
著者Shimizu, H, Park, S.-Y.
登録日2000-05-23
公開日2000-11-23
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Mutation effects of a conserved threonine (Thr243) of cytochrome P450nor on its structure and function.
J.Inorg.Biochem., 82, 2000
5B3V
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BU of 5b3v by Molmil
Crystal structure of biliverdin reductase in complex with biliverdin and NADP+ from Synechocystis sp. PCC 6803
分子名称: BILIVERDINE IX ALPHA, Biliverdin reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Takao, H, Wada, K.
登録日2016-03-13
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.594 Å)
主引用文献A substrate-bound structure of cyanobacterial biliverdin reductase identifies stacked substrates as critical for activity
Nat Commun, 8, 2017
5B3U
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BU of 5b3u by Molmil
Crystal structure of biliverdin reductase in complex with NADP+ from Synechocystis sp. PCC 6803
分子名称: Biliverdin reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PHOSPHATE ION
著者Takao, H, Wada, K.
登録日2016-03-13
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.698 Å)
主引用文献A substrate-bound structure of cyanobacterial biliverdin reductase identifies stacked substrates as critical for activity
Nat Commun, 8, 2017
5B3T
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BU of 5b3t by Molmil
Crystal structure of apo-form biliverdin reductase from Synechocystis sp. PCC 6803
分子名称: Biliverdin reductase, PHOSPHATE ION
著者Takao, H, Wada, K.
登録日2016-03-12
公開日2017-02-15
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献A substrate-bound structure of cyanobacterial biliverdin reductase identifies stacked substrates as critical for activity
Nat Commun, 8, 2017
1IUL
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BU of 1iul by Molmil
The structure of cell-free ID.343 from Thermus thermophilus
分子名称: hypothetical protein TT1466
著者Wada, T, Shirouzu, M, Park, S.-Y, Tame, J.R, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-03-05
公開日2003-07-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of a conserved CoA-binding protein synthesized by a cell-free system.
Acta Crystallogr.,Sect.D, 59, 2003
5ZYB
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BU of 5zyb by Molmil
Crystal structure of MOX-1 complexed with a boronic acid transition state inhibitor S02030
分子名称: 1-{(2R)-2-(dihydroxyboranyl)-2-[(thiophen-2-ylacetyl)amino]ethyl}-1H-1,2,3-triazole-4-carboxylic acid, ACETATE ION, Beta-lactamase, ...
著者Shimizu-Ibuka, A, Furukawa, N.
登録日2018-05-23
公開日2019-06-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Crystal structure of MOX-1 complexed with a boronic acid transition state inhibitor S02030
To Be Published
6AAM
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BU of 6aam by Molmil
Crystal structure of TYK2 in complex with peficitinib
分子名称: 4-[[(1S,3R)-5-oxidanyl-2-adamantyl]amino]-1H-pyrrolo[2,3-b]pyridine-5-carboxamide, Non-receptor tyrosine-protein kinase TYK2
著者Nomura, N, Tomimoto, Y.
登録日2018-07-18
公開日2018-08-15
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Discovery and structural characterization of peficitinib (ASP015K) as a novel and potent JAK inhibitor
Bioorg. Med. Chem., 26, 2018
1HSR
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BU of 1hsr by Molmil
BINDING MODE OF BENZHYDROXAMIC ACID TO ARTHROMYCES RAMOSUS PEROXIDASE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BENZHYDROXAMIC ACID, CALCIUM ION, ...
著者Fukuyama, K, Itakura, H.
登録日1997-07-01
公開日1998-07-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Binding mode of benzhydroxamic acid to Arthromyces ramosus peroxidase shown by X-ray crystallographic analysis of the complex at 1.6 A resolution.
FEBS Lett., 412, 1997

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