4MNF
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![BU of 4mnf by Molmil](/molmil-images/mine/4mnf) | Crystal structure of BRAF-V600E bound to GDC0879 | 分子名称: | 2-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-inden-5-yl]-3-(pyridin-4-yl)-1H-pyrazol-1-yl}ethanol, CHLORIDE ION, Serine/threonine-protein kinase B-raf | 著者 | Sudhamsu, J, Haling, J.R, Morales, T, Brandhuber, B, Hymowitz, S.G. | 登録日 | 2013-09-10 | 公開日 | 2014-06-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | 主引用文献 | Structure of the BRAF-MEK Complex Reveals a Kinase Activity Independent Role for BRAF in MAPK Signaling. Cancer Cell, 26, 2014
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4N23
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![BU of 4n23 by Molmil](/molmil-images/mine/4n23) | Crystal structure of the GP2 Core Domain from the California Academy of Science Virus, monoclinic symmetry | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, GP2 Ectodomain | 著者 | Malashkevich, V.N, Koellhoffer, J.F, Dai, Z, Toro, R, Lai, J.R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2013-10-04 | 公開日 | 2013-11-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Characterization of the Glycoprotein GP2 Core Domain from the CAS Virus, a Novel Arenavirus-Like Species. J.Mol.Biol., 426, 2014
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4OC8
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4OD1
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![BU of 4od1 by Molmil](/molmil-images/mine/4od1) | Crystal structure of human Fab CAP256-VRC26.03, a potent V1V2-directed HIV-1 neutralizing antibody | 分子名称: | CAP256-VRC26.03 heavy chain, CAP256-VRC26.03 light chain | 著者 | Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D. | 登録日 | 2014-01-09 | 公開日 | 2014-02-26 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature, 509, 2014
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4OPF
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![BU of 4opf by Molmil](/molmil-images/mine/4opf) | Streptomcyes albus JA3453 oxazolomycin ketosynthase domain OzmH KS8 | 分子名称: | NRPS/PKS | 著者 | Osipiuk, J, Bigelow, L, Endres, M, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2014-02-05 | 公開日 | 2014-02-19 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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4OO2
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![BU of 4oo2 by Molmil](/molmil-images/mine/4oo2) | Streptomyces globisporus C-1027 FAD dependent (S)-3-chloro-β-tyrosine-S-SgcC2 C-5 hydroxylase SgcC apo form | 分子名称: | CALCIUM ION, Chlorophenol-4-monooxygenase, GLYCEROL | 著者 | Cao, H, Xu, W, Bingman, C.A, Lohman, J.R, Yennamalli, R, Shen, B, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2014-01-29 | 公開日 | 2014-02-12 | 最終更新日 | 2023-03-22 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus. Biochemistry, 55, 2016
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4OWC
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![BU of 4owc by Molmil](/molmil-images/mine/4owc) | PtI6 binding to HEWL | 分子名称: | CHLORIDE ION, IODIDE ION, Lysozyme C, ... | 著者 | Tanley, S.W.M, Starkey, V.L, Lamplough, L, Kaenket, S, Helliwell, J.R. | 登録日 | 2014-01-31 | 公開日 | 2014-09-24 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | The binding of platinum hexahalides (Cl, Br and I) to hen egg-white lysozyme and the chemical transformation of the PtI6 octahedral complex to a PtI3 moiety bound to His15. Acta Crystallogr.,Sect.F, 70, 2014
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4N21
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![BU of 4n21 by Molmil](/molmil-images/mine/4n21) | Crystal structure of the GP2 Core Domain from the California Academy of Science Virus | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GP2 Ectodomain | 著者 | Malashkevich, V.N, Koellhoffer, J.F, Dai, Z, Toro, R, Lai, J.R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2013-10-04 | 公開日 | 2013-11-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structural Characterization of the Glycoprotein GP2 Core Domain from the CAS Virus, a Novel Arenavirus-Like Species. J.Mol.Biol., 426, 2014
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4MT0
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4N4Q
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![BU of 4n4q by Molmil](/molmil-images/mine/4n4q) | Crystal Structure of N-acetylneuraminate lyase from Mycoplasma synoviae, crystal form II | 分子名称: | Acylneuraminate lyase | 著者 | Georgescauld, F, Popova, K, Gupta, A.J, Bracher, A, Engen, J.R, Hayer-Hartl, M, Hartl, F.U. | 登録日 | 2013-10-08 | 公開日 | 2014-05-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | GroEL/ES Chaperonin Modulates the Mechanism and Accelerates the Rate of TIM-Barrel Domain Folding. Cell(Cambridge,Mass.), 157, 2014
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4OCR
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![BU of 4ocr by Molmil](/molmil-images/mine/4ocr) | Crystal structure of human Fab CAP256-VRC26.01, a potent V1V2-directed HIV-1 neutralizing antibody | 分子名称: | CAP256-VRC26.01 heavy chain, CAP256-VRC26.01 light chain | 著者 | Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D. | 登録日 | 2014-01-09 | 公開日 | 2014-02-26 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.895 Å) | 主引用文献 | Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature, 509, 2014
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4OWB
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4OWH
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![BU of 4owh by Molmil](/molmil-images/mine/4owh) | PtBr6 binding to HEWL | 分子名称: | ACETATE ION, BROMIDE ION, CHLORIDE ION, ... | 著者 | Tanley, S.W.M, Starkey, V.L, Lamplough, L, Kaenket, S, Helliwell, J.R. | 登録日 | 2014-02-02 | 公開日 | 2014-09-24 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.484 Å) | 主引用文献 | The binding of platinum hexahalides (Cl, Br and I) to hen egg-white lysozyme and the chemical transformation of the PtI6 octahedral complex to a PtI3 moiety bound to His15. Acta Crystallogr.,Sect.F, 70, 2014
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4OXM
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4NKG
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![BU of 4nkg by Molmil](/molmil-images/mine/4nkg) | Crystal structure of SspH1 LRR domain in complex PKN1 HR1b domain | 分子名称: | E3 ubiquitin-protein ligase sspH1, HEXANE-1,6-DIOL, Serine/threonine-protein kinase N1 | 著者 | Keszei, A.F.A, Xiaojing, T, Mccormick, C, Zeqiraj, E, Rohde, J.R, Tyers, M, Sicheri, F. | 登録日 | 2013-11-12 | 公開日 | 2013-12-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin Ligase. Mol.Cell.Biol., 34, 2014
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4NSH
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![BU of 4nsh by Molmil](/molmil-images/mine/4nsh) | Carboplatin binding to HEWL in 0.2M NH4SO4, 0.1M NaAc in 25% PEG 4000 at pH 4.6 | 分子名称: | ACETATE ION, DIMETHYL SULFOXIDE, Lysozyme C, ... | 著者 | Tanley, S.W.M, Diederichs, K, Kroon-Batenburg, L.M.J, Levy, C, Schreurs, A.M.M, Helliwell, J.R. | 登録日 | 2013-11-28 | 公開日 | 2014-10-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Carboplatin binding to histidine. Acta Crystallogr F Struct Biol Commun, 70, 2014
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4NSG
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![BU of 4nsg by Molmil](/molmil-images/mine/4nsg) | Carboplatin binding to HEWL in NaBr crystallisation conditions studied at an X-ray wavelength of 1.5418A | 分子名称: | ACETATE ION, BROMIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Tanley, S.W.M, Diederichs, K, Kroon-Batenburg, L.M.J, Levy, C, Schreurs, A.M.M, Helliwell, J.R. | 登録日 | 2013-11-28 | 公開日 | 2014-10-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Carboplatin binding to histidine. Acta Crystallogr F Struct Biol Commun, 70, 2014
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4NU5
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![BU of 4nu5 by Molmil](/molmil-images/mine/4nu5) | Crystal Structure of PTDH R301A | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Phosphonate dehydrogenase | 著者 | Nair, S.K, Chekan, J.R. | 登録日 | 2013-12-03 | 公開日 | 2014-03-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Chemical rescue and inhibition studies to determine the role of arg301 in phosphite dehydrogenase. Plos One, 9, 2014
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4NXJ
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![BU of 4nxj by Molmil](/molmil-images/mine/4nxj) | Crystal Structure of PF3D7_1475600, a bromodomain from Plasmodium Falciparum | 分子名称: | Bromodomain protein | 著者 | Wernimont, A.K, Loppnau, P, Knapp, S, Fonseca, M, Brennan, P.E, Dong, A, Walker, J.R, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Hutchinson, A, Structural Genomics Consortium (SGC) | 登録日 | 2013-12-09 | 公開日 | 2014-03-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Crystal Structure of PF3D7_1475600, a bromodomain from Plasmodium Falciparum TO BE PUBLISHED
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4PLH
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![BU of 4plh by Molmil](/molmil-images/mine/4plh) | Crystal structure of ancestral apicomplexan malate dehydrogenase with oxamate. | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, OXAMIC ACID, SODIUM ION, ... | 著者 | Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L. | 登録日 | 2014-05-16 | 公開日 | 2014-07-02 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases. Elife, 3, 2014
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4P16
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![BU of 4p16 by Molmil](/molmil-images/mine/4p16) | Crystal structure of the papain-like protease of Middle-East Respiratory Syndrome coronavirus | 分子名称: | ORF1a, ZINC ION | 著者 | Lei, J, Mesters, J.R, Ma, Q, Hilgenfeld, R. | 登録日 | 2014-02-25 | 公開日 | 2014-05-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of the papain-like protease of MERS coronavirus reveals unusual, potentially druggable active-site features. Antiviral Res., 109C, 2014
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4PBB
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1NT2
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![BU of 1nt2 by Molmil](/molmil-images/mine/1nt2) | CRYSTAL STRUCTURE OF FIBRILLARIN/NOP5P COMPLEX | 分子名称: | Fibrillarin-like pre-rRNA processing protein, S-ADENOSYLMETHIONINE, conserved hypothetical protein | 著者 | Aittaleb, M, Rashid, R, Chen, Q, Palmer, J.R, Daniels, C.J, Li, H. | 登録日 | 2003-01-28 | 公開日 | 2003-04-01 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure and function of archaeal box C/D sRNP core proteins. Nat.Struct.Biol., 10, 2003
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1NYN
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![BU of 1nyn by Molmil](/molmil-images/mine/1nyn) | Solution NMR Structure of Protein YHR087W from Saccharomyces cerevisiae. Northeast Structural Genomics Consortium Target YTYST425. | 分子名称: | Hypothetical 12.0 kDa protein in NAM8-GAR1 intergenic region | 著者 | Cort, J.R, Yee, A.A, Arrowsmith, C.H, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2003-02-13 | 公開日 | 2003-04-08 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism. J.Biol.Chem., 280, 2005
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1O5E
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![BU of 1o5e by Molmil](/molmil-images/mine/1o5e) | Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA) | 分子名称: | 6-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE, Serine protease hepsin | 著者 | Katz, B.A, Luong, C, Ho, J.D, Somoza, J.R, Gjerstad, E, Tang, J, Williams, S.R, Verner, E, Mackman, R.L, Young, W.B, Sprengeler, P.A, Chan, H, Mortara, K, Janc, J.W, McGrath, M.E. | 登録日 | 2003-09-09 | 公開日 | 2004-09-21 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA). J.Mol.Biol., 344, 2004
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