4IWX
| Rimk structure at 2.85A | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLUTAMIC ACID, Ribosomal protein S6 modification protein, ... | 著者 | Shi, D, Zhao, G, Jin, Z, Allewell, N.M, Tuchman, M. | 登録日 | 2013-01-24 | 公開日 | 2013-05-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.854 Å) | 主引用文献 | Structure and function of Escherichia coli RimK, an ATP-grasp fold, l-glutamyl ligase enzyme. Proteins, 81, 2013
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4P4R
| Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergic Hypersensitivity and Autoimmunity | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DP alpha 1 chain, ... | 著者 | Clayton, G.M, Crawford, F, Kappler, J.W. | 登録日 | 2014-03-13 | 公開日 | 2014-07-16 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell, 158, 2014
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4P61
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7V9P
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7V9Q
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7V9O
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7V9N
| Crystal structure of the lanthipeptide zinc-metallopeptidase EryP from saccharopolyspora erythraea in closed state | 分子名称: | ACETATE ION, Alanine aminopeptidase, CALCIUM ION, ... | 著者 | Zhao, C, Zhao, N.L, Bao, R. | 登録日 | 2021-08-26 | 公開日 | 2022-05-11 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Conformational remodeling enhances activity of lanthipeptide zinc-metallopeptidases. Nat.Chem.Biol., 18, 2022
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4PNU
| E. coli sliding clamp in complex with (R)-6-bromo-9-(2-((R)-1-carboxy-2-phenylethylamino)-2-oxoethyl)-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid | 分子名称: | (2R)-6-bromo-9-(2-{[(1R)-1-carboxy-2-phenylethyl]amino}-2-oxoethyl)-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid, CALCIUM ION, CHLORIDE ION, ... | 著者 | Yin, Z, Oakley, A.J. | 登録日 | 2014-02-21 | 公開日 | 2014-03-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs. J.Med.Chem., 58, 2015
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2HNK
| Crystal structure of SAM-dependent O-methyltransferase from pathogenic bacterium Leptospira interrogans | 分子名称: | DI(HYDROXYETHYL)ETHER, S-ADENOSYL-L-HOMOCYSTEINE, SAM-dependent O-methyltransferase, ... | 著者 | Hou, X, Wei, Z, Gong, W. | 登録日 | 2006-07-13 | 公開日 | 2007-09-04 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of SAM-dependent O-methyltransferase from pathogenic bacterium Leptospira interrogans. J.Struct.Biol., 159, 2007
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2I6K
| Crystal structure of human type I IPP isomerase complexed with a substrate analog | 分子名称: | ACETIC ACID, AMINOETHANOLPYROPHOSPHATE, Isopentenyl-diphosphate delta-isomerase 1, ... | 著者 | Zhang, C, Wei, Z, Gong, W. | 登録日 | 2006-08-29 | 公開日 | 2007-06-05 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of human IPP isomerase: new insights into the catalytic mechanism J.Mol.Biol., 366, 2007
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7WVN
| SARS-CoV-2 Omicron S-open | 分子名称: | Spike glycoprotein | 著者 | Li, J.W, Cong, Y. | 登録日 | 2022-02-10 | 公開日 | 2022-03-02 | 最終更新日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Molecular basis of receptor binding and antibody neutralization of Omicron. Nature, 604, 2022
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7WVO
| SARS-CoV-2 Omicron S-open-2 | 分子名称: | Spike glycoprotein | 著者 | Li, J.W, Cong, Y. | 登録日 | 2022-02-10 | 公開日 | 2022-03-02 | 最終更新日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | 主引用文献 | Molecular basis of receptor binding and antibody neutralization of Omicron. Nature, 604, 2022
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3QKJ
| The PWWP domain of human DNA (CYTOSINE-5-)-METHYLTRANSFERASE 3 BETA in complex with a bis-tris molecule | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA cytosine-5 methyltransferase 3 beta isoform 6 variant, SULFATE ION | 著者 | Zeng, H, Amaya, M.F, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Min, J, Wu, H, Structural Genomics Consortium (SGC) | 登録日 | 2011-02-01 | 公開日 | 2011-03-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Structural and Histone Binding Ability Characterizations of Human PWWP Domains. Plos One, 6, 2011
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7DSZ
| Crystal structure of Amuc_1102 from Akkermansia muciniphila | 分子名称: | Amuc_1102, CHLORIDE ION | 著者 | Xiang, R, Wang, J, Wang, Y, Zhang, M, Wang, M. | 登録日 | 2021-01-04 | 公開日 | 2021-02-24 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Amuc_1102 fromAkkermansia muciniphilaadopts animmunoglobulin-like fold related to archaeal type IV pilus Biochem.Biophys.Res.Commun., 547, 2021
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7WV9
| Allosteric modulator ZCZ011 binding to CP55940-bound cannabinoid receptor 1 in complex with Gi protein | 分子名称: | 2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol, 6-methyl-3-[(1S)-2-nitro-1-thiophen-2-yl-ethyl]-2-phenyl-1H-indole, Cannabinoid receptor 1, ... | 著者 | Xu, Z, Shao, Z. | 登録日 | 2022-02-10 | 公開日 | 2022-06-15 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | 主引用文献 | Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1. Nat.Chem.Biol., 18, 2022
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4PNV
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5VOU
| Structure of AMPA receptor-TARP complex | 分子名称: | Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit | 著者 | Chen, S, Zhao, Y, Wang, Y.S, Shekhar, M, Tajkhorshid, E, Gouaux, E. | 登録日 | 2017-05-03 | 公開日 | 2017-07-12 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (6.4 Å) | 主引用文献 | Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM. Cell, 170, 2017
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7Z1H
| VAR2CSA APO | 分子名称: | VAR2CSA APO | 著者 | Raghavan, S.S.R, Wang, K.T. | 登録日 | 2022-02-24 | 公開日 | 2022-11-02 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA. Plos Pathog., 18, 2022
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4IWY
| SeMet-substituted RimK structure | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLUTAMIC ACID, Ribosomal protein S6 modification protein, ... | 著者 | Shi, D, Zhao, G, Jin, Z, Allewell, N.M, Tuchman, M. | 登録日 | 2013-01-24 | 公開日 | 2013-05-08 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure and function of Escherichia coli RimK, an ATP-grasp fold, l-glutamyl ligase enzyme. Proteins, 81, 2013
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4RXE
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7Z12
| VAR2 complex with PAM1.4 | 分子名称: | PAM1.4, Heavy Chain, light Chain, ... | 著者 | Raghavan, S.S.R, Wang, K.T. | 登録日 | 2022-02-24 | 公開日 | 2022-11-02 | 最終更新日 | 2022-11-30 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA. Plos Pathog., 18, 2022
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4QNV
| Crystal structure of Cx-SAM bound CmoB from E. coli in P6122 | 分子名称: | (2S)-4-[{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}(carboxylatomethyl)sulfonio] -2-ammoniobutanoate, PHOSPHATE ION, tRNA (mo5U34)-methyltransferase | 著者 | Kim, J, Toro, R, Bhosle, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2014-06-18 | 公開日 | 2014-09-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Determinants of the CmoB carboxymethyl transferase utilized for selective tRNA wobble modification. Nucleic Acids Res., 43, 2015
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4RXC
| T. Brucei Farnesyl Diphosphate Synthase Complexed with Homorisedronate BPH-6 | 分子名称: | Farnesyl pyrophosphate synthase, MAGNESIUM ION, [1-hydroxy-3-(pyridin-3-yl)propane-1,1-diyl]bis(phosphonic acid) | 著者 | Cao, R, Liu, Y.-L, Oldfield, E. | 登録日 | 2014-12-09 | 公開日 | 2015-04-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Farnesyl diphosphate synthase inhibitors with unique ligand-binding geometries. ACS Med Chem Lett, 6, 2015
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3R0Y
| Crystal Structures of Multidrug-resistant HIV-1 Protease in Complex with Mechanism-Based Aspartyl Protease Inhibitors | 分子名称: | Multidrug-resistant clinical isolate 769 HIV-1 Protease, N-[(2S)-1-{[(2S,3S)-3-hydroxy-5-oxo-5-{[(2R)-1-oxo-3-phenyl-1-(prop-2-yn-1-ylamino)propan-2-yl]amino}-1-phenylpentan-2-yl]amino}-3-methyl-1-oxobutan-2-yl]pyridine-2-carboxamide | 著者 | Yedidi, R.S, Gupta, D, Liu, Z, Brunzelle, J, Kovari, I.A, Woster, P.M, Kovari, L.C. | 登録日 | 2011-03-09 | 公開日 | 2012-04-04 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structures of multidrug-resistant HIV-1 protease in complex with two potent anti-malarial compounds. Biochem.Biophys.Res.Commun., 421, 2012
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5Z7G
| Crystal structure of TAX1BP1 SKICH region in complex with NAP1 | 分子名称: | 5-azacytidine-induced protein 2, GLYCEROL, Tax1-binding protein 1 | 著者 | Pan, L.F, Fu, T, Liu, J.P, Xie, X.Q, Wang, Y.L, Hu, S.C. | 登録日 | 2018-01-28 | 公開日 | 2019-01-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Mechanistic insights into the interactions of NAP1 with the SKICH domains of NDP52 and TAX1BP1 Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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