4GD4
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![BU of 4gd4 by Molmil](/molmil-images/mine/4gd4) | Crystal Structure of JMJD2A Complexed with Inhibitor | 分子名称: | 2-(1H-pyrazol-3-yl)pyridine-4-carboxylic acid, CHLORIDE ION, Lysine-specific demethylase 4A, ... | 著者 | King, O.N.F, Krojer, T, Arrowsmith, C.H, Edwards, A, Bountra, C, McDonough, M.A, Schofield, C.J, Structural Genomics Consortium (SGC) | 登録日 | 2012-07-31 | 公開日 | 2012-08-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Crystal Structure of JMJD2A Complexed with Inhibitor TO BE PUBLISHED
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4IHP
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![BU of 4ihp by Molmil](/molmil-images/mine/4ihp) | Crystal structure of TgCDPK1 with inhibitor bound | 分子名称: | 1-tert-butyl-3-(3-chlorophenoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1, UNKNOWN ATOM OR ION | 著者 | El Bakkouri, M, Tempel, W, Crandall, I.E, Massad, T, Loppnau, P, Graslund, S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Kain, C.K, Shokat, K.M, Sibley, L.D, Hui, R, Structural Genomics Consortium (SGC) | 登録日 | 2012-12-19 | 公開日 | 2014-01-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Crystal structure of TgCDPK1 with inhibitor bound TO BE PUBLISHED
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4IJD
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![BU of 4ijd by Molmil](/molmil-images/mine/4ijd) | Crystal structure of methyltransferase domain of human PR domain-containing protein 9 | 分子名称: | Histone-lysine N-methyltransferase PRDM9, UNKNOWN ATOM OR ION, ZINC ION | 著者 | Dong, A, Dombrovski, L, Li, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Wu, H, Structural Genomics Consortium (SGC) | 登録日 | 2012-12-21 | 公開日 | 2013-02-13 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structure of methyltransferase domain of human PR domain-containing protein 9 To be Published
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4FUK
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![BU of 4fuk by Molmil](/molmil-images/mine/4fuk) | Aminopeptidase from Trypanosoma brucei | 分子名称: | GLYCEROL, Methionine aminopeptidase, UNKNOWN ATOM OR ION, ... | 著者 | El Bakkouri, M, Tempel, W, Osman, K.T, Loppnau, P, Graslund, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Lin, Y.H, Structural Genomics Consortium (SGC) | 登録日 | 2012-06-28 | 公開日 | 2012-08-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Aminpeptidase from Trypanosoma brucei (CASP Target) To be Published
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4IIM
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![BU of 4iim by Molmil](/molmil-images/mine/4iim) | Crystal structure of the Second SH3 Domain of ITSN1 bound with a synthetic peptide | 分子名称: | Intersectin-1, UNKNOWN ATOM OR ION, peptide ligand | 著者 | Dong, A, Guan, X, Huang, H, Wernimont, A, Gu, J, Sidhu, S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | 登録日 | 2012-12-20 | 公開日 | 2013-01-23 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of the Second SH3 Domain of ITSN1 bound with a synthetic peptide To be Published
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4IJ8
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![BU of 4ij8 by Molmil](/molmil-images/mine/4ij8) | Crystal structure of the complex of SETD8 with SAM | 分子名称: | N-lysine methyltransferase SETD8, S-ADENOSYLMETHIONINE, UNKNOWN ATOM OR ION, ... | 著者 | Yu, W, Tempel, W, Li, Y, El Bakkouri, M, Shapira, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC) | 登録日 | 2012-12-21 | 公開日 | 2013-01-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the complex of SETD8 with SAM To be Published
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4JXM
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![BU of 4jxm by Molmil](/molmil-images/mine/4jxm) | Crystal structure of RRP9 WD40 repeats | 分子名称: | U3 small nucleolar RNA-interacting protein 2, UNKNOWN ATOM OR ION | 著者 | Wu, X, Tempel, W, Xu, C, El Bakkouri, M, He, H, Seitova, A, Li, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2013-03-28 | 公開日 | 2013-04-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Crystal structure of RRP9 WD40 repeats To be Published
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4LD6
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![BU of 4ld6 by Molmil](/molmil-images/mine/4ld6) | PWWP domain of human PWWP Domain-Containing Protein 2B | 分子名称: | GLYCEROL, PWWP domain-containing protein 2B, UNKNOWN ATOM OR ION | 著者 | Dong, A, Dombrovski, L, Tempel, W, Loppnau, P, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Wu, H, Structural Genomics Consortium (SGC) | 登録日 | 2013-06-24 | 公開日 | 2013-07-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of PWWP domain of human PWWP Domain-Containing Protein 2B To be Published
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4LG1
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![BU of 4lg1 by Molmil](/molmil-images/mine/4lg1) | Human Methyltransferase-Like Protein 21D | 分子名称: | 1,2-ETHANEDIOL, Protein-lysine methyltransferase METTL21D, S-ADENOSYLMETHIONINE, ... | 著者 | Dong, A, Zeng, H, Fenner, M, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Wu, H, Structural Genomics Consortium (SGC) | 登録日 | 2013-06-27 | 公開日 | 2013-07-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Crystal Structure of Human Methyltransferase-Like Protein 21D in Complex with SAM To be Published
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4MVT
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![BU of 4mvt by Molmil](/molmil-images/mine/4mvt) | Crystal structure of SUMO E3 Ligase PIAS3 | 分子名称: | CHLORIDE ION, E3 SUMO-protein ligase PIAS3, UNKNOWN ATOM OR ION, ... | 著者 | Dong, A, Hu, J, Li, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | 登録日 | 2013-09-24 | 公開日 | 2013-10-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of SUMO E3 Ligase PIAS3 to be published
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4NR2
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![BU of 4nr2 by Molmil](/molmil-images/mine/4nr2) | Crystal structure of STK4 (MST1) SARAH domain | 分子名称: | 1,2-ETHANEDIOL, Serine/threonine-protein kinase 4 | 著者 | Chaikuad, A, Krojer, T, Kopec, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2013-11-26 | 公開日 | 2014-01-29 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of STK4 (MST1) SARAH domain To be Published
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4O2Z
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![BU of 4o2z by Molmil](/molmil-images/mine/4o2z) | Crystal Structure of MPK3 from Leishmania donovani, LdBPK_100540 in the presence of NVP-BBT594 | 分子名称: | 5-{[6-(acetylamino)pyrimidin-4-yl]oxy}-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-2,3-dihydro-1H-indole-1-carboxamide, Mitogen-activated protein kinase 3, putative | 著者 | Wernimont, A.K, Walker, J.R, Hutchinson, A, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Hui, R, Mangos, M, Structural Genomics Consortium (SGC) | 登録日 | 2013-12-17 | 公開日 | 2014-01-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Crystal Structure of MPK3 from Leishmania donovani, LdBPK_100540 in the presence of NVP-BBT594 To be Published
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4O2W
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![BU of 4o2w by Molmil](/molmil-images/mine/4o2w) | Crystal structure of the third RCC1-like domain of HERC1 | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase HERC1, MAGNESIUM ION, ... | 著者 | Dong, A, Hu, J, Li, Y, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | 登録日 | 2013-12-17 | 公開日 | 2014-01-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the third RCC1-like domain of HERC1 To be Published
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3L6Q
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![BU of 3l6q by Molmil](/molmil-images/mine/3l6q) | Crystal structure of the N-terminal domain of HSP70 from Cryptosporidium parvum (CGD2_20) | 分子名称: | Heat shock 70 (HSP70) protein, MAGNESIUM ION, SULFATE ION | 著者 | Pizarro, J.C, Wernimont, A.K, Hutchinson, A, Sullivan, H, Lew, J, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Hills, T, Structural Genomics Consortium (SGC) | 登録日 | 2009-12-24 | 公開日 | 2010-02-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Crystal structure of the N-terminal domain of HSP70 from Cryptosporidium parvum (CGD2_20) To be Published
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3PFV
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![BU of 3pfv by Molmil](/molmil-images/mine/3pfv) | Crystal structure of Cbl-b TKB domain in complex with EGFR pY1069 peptide | 分子名称: | 1,2-ETHANEDIOL, 11-meric peptide from Epidermal growth factor receptor, CHLORIDE ION, ... | 著者 | Chaikuad, A, Guo, K, Cooper, C.D.O, Ayinampudi, V, Krojer, T, Muniz, J.R.C, Vollmar, M, Canning, P, Gileadi, O, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) | 登録日 | 2010-10-29 | 公開日 | 2010-12-08 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Crystal structure of Cbl-b TKB domain in complex with EGFR pY1069 peptide To be Published
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3PRY
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![BU of 3pry by Molmil](/molmil-images/mine/3pry) | Crystal structure of the middle domain of human HSP90-beta refined at 2.3 A resolution | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Heat shock protein HSP 90-beta, ... | 著者 | Chaikuad, A, Pilka, E, Sharpe, T.D, Cooper, C.D.O, Phillips, C, Berridge, G, Ayinampudi, V, Fedorov, O, Keates, T, Thangaratnarajah, C, Zimmermann, T, Vollmar, M, Yue, W.W, Che, K.H, Krojer, T, Muniz, J.R.C, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bullock, A, Structural Genomics Consortium (SGC) | 登録日 | 2010-11-30 | 公開日 | 2010-12-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Crystal structure of the middle domain of human HSP90-beta refined at 2.3 A resolution To be Published
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1Z6U
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![BU of 1z6u by Molmil](/molmil-images/mine/1z6u) | Np95-like ring finger protein isoform b [Homo sapiens] | 分子名称: | Np95-like ring finger protein isoform b, ZINC ION | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2005-03-23 | 公開日 | 2005-05-03 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | 2.1 Angstrom Crystal Structure of the Human Ubiquitin Liagse NIRF To be Published
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3DYD
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![BU of 3dyd by Molmil](/molmil-images/mine/3dyd) | Human Tyrosine Aminotransferase | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, Tyrosine aminotransferase | 著者 | Karlberg, T, Moche, M, Andersson, J, Arrowsmith, C.H, Berglund, H, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kotenyova, T, Lehtio, L, Nilsson, M.E, Nordlund, P, Nyman, T, Olesen, K, Persson, C, Sagemark, J, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wikstrom, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) | 登録日 | 2008-07-27 | 公開日 | 2008-08-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Human Tyrosine Aminotransferase To be Published
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3E77
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![BU of 3e77 by Molmil](/molmil-images/mine/3e77) | Human phosphoserine aminotransferase in complex with PLP | 分子名称: | GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, Phosphoserine aminotransferase | 著者 | Lehtio, L, Karlberg, T, Andersson, J, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Olesen, K, Persson, C, Sagemark, J, Thorsell, S.G, Tresaugues, L, Van Den Berg, S, Welin, M, Wikstrom, M, Wisniewska, M, Weigelt, J, Schueler, H, Structural Genomics Consortium (SGC) | 登録日 | 2008-08-18 | 公開日 | 2008-08-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Human phosphoserine aminotransferase in complex with PLP TO BE PUBLISHED
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3PFY
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![BU of 3pfy by Molmil](/molmil-images/mine/3pfy) | The catalytic domain of human OTUD5 | 分子名称: | DI(HYDROXYETHYL)ETHER, OTU domain-containing protein 5, SULFATE ION, ... | 著者 | Walker, J.R, Asinas, A.E, Crombet, L, Dong, A, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2010-10-29 | 公開日 | 2010-12-15 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | 主引用文献 | The catalytic domain of human OTUD5 To be Published
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3PS4
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![BU of 3ps4 by Molmil](/molmil-images/mine/3ps4) | PDZ domain from Human microtubule-associated serine/threonine-protein kinase 1 | 分子名称: | 1,2-ETHANEDIOL, IMIDAZOLE, Microtubule-associated serine/threonine-protein kinase 1 | 著者 | Ugochukwu, E, Wang, J, Krojer, T, Muniz, J.R.C, Sethi, R, Pike, A.C.W, Roos, A, Salah, E, Cocking, R, Savitsky, P, Doyle, D.A, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Knapp, S, Elkins, J.M, Structural Genomics Consortium (SGC) | 登録日 | 2010-11-30 | 公開日 | 2010-12-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | PDZ domain from Human microtubule-associated serine/threonine-protein kinase 1 TO BE PUBLISHED
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3NR9
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![BU of 3nr9 by Molmil](/molmil-images/mine/3nr9) | Structure of human CDC2-like kinase 2 (CLK2) | 分子名称: | (5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-one, Dual specificity protein kinase CLK2 | 著者 | Chaikuad, A, Savitsky, P, Krojer, T, Muniz, J.R.C, Filippakopoulos, P, Rellos, P, Keates, T, Fedorov, O, Pike, A.C.W, Eswaran, J, Berridge, G, Phillips, C, Zhang, Y, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2010-06-30 | 公開日 | 2010-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Structure of human CDC2-like kinase 2 (CLK2) To be Published
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3MDY
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![BU of 3mdy by Molmil](/molmil-images/mine/3mdy) | Crystal structure of the cytoplasmic domain of the bone morphogenetic protein receptor type-1B (BMPR1B) in complex with FKBP12 and LDN-193189 | 分子名称: | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline, Bone morphogenetic protein receptor type-1B, Peptidyl-prolyl cis-trans isomerase FKBP1A | 著者 | Chaikuad, A, Sanvitale, C, Mahajan, P, Daga, N, Cooper, C, Krojer, T, Alfano, I, Knapp, S, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) | 登録日 | 2010-03-31 | 公開日 | 2010-05-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structure of the cytoplasmic domain of the bone morphogenetic protein receptor type-1B (BMPR1B) in complex with FKBP12 and LDN-193189 To be Published
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3MSE
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![BU of 3mse by Molmil](/molmil-images/mine/3mse) | Crystal structure of C-terminal domain of PF110239. | 分子名称: | CALCIUM ION, Calcium-dependent protein kinase, putative, ... | 著者 | Wernimont, A.K, Artz, J.D, Hutchinson, A, Sullivan, H, Weadge, J, Tempel, W, Bochkarev, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Hui, R, Lin, Y.H, Neculai, A.M, Amani, M, Structural Genomics Consortium (SGC) | 登録日 | 2010-04-29 | 公開日 | 2010-06-23 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of C-terminal domain of PF110239 To be Published
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3P1F
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![BU of 3p1f by Molmil](/molmil-images/mine/3p1f) | Crystal structure of the bromodomain of human CREBBP in complex with a hydroquinazolin ligand | 分子名称: | 1,2-ETHANEDIOL, 3-methyl-3,4-dihydroquinazolin-2(1H)-one, CREB-binding protein, ... | 著者 | Filippakopoulos, P, Picaud, S, Fedorov, O, Muniz, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2010-09-30 | 公開日 | 2010-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Crystal structure of the bromodomain of human CREBBP in complex with a hydroquinazolin ligand To be Published
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