1N0T
| X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with the antagonist (S)-ATPO at 2.1 A resolution. | 分子名称: | (S)-2-AMINO-3-(5-TERT-BUTYL-3-(PHOSPHONOMETHOXY)-4-ISOXAZOLYL)PROPIONIC ACID, ACETATE ION, Glutamate receptor 2, ... | 著者 | Hogner, A, Greenwood, J.R, Liljefors, T, Lunn, M.-L, Egebjerg, J, Larsen, I.K, Gouaux, E, Kastrup, J.S. | 登録日 | 2002-10-15 | 公開日 | 2003-03-04 | 最終更新日 | 2017-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Competitive antagonism of AMPA receptors by ligands of
different classes: crystal structure of ATPO bound to the
GluR2 ligand-binding core, in comparison with DNQX. J.Med.Chem., 46, 2003
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2MN2
| 3D structure of YmoB, a modulator of biofilm formation | 分子名称: | YmoB | 著者 | Marimon, O, Cordeiro, T.N, Amata, I, Pons, M. | 登録日 | 2014-03-26 | 公開日 | 2015-04-01 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | An oxygen-sensitive toxin-antitoxin system. Nat Commun, 7, 2016
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6Q7Q
| Crystal structure of OE1.3 | 分子名称: | OE1.3 | 著者 | Levy, C.W. | 登録日 | 2018-12-13 | 公開日 | 2019-06-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Design and evolution of an enzyme with a non-canonical organocatalytic mechanism. Nature, 570, 2019
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3H6U
| Crystal structure of the iGluR2 ligand-binding core (S1S2J-N754S) in complex with glutamate and NS1493 at 1.85 A resolution | 分子名称: | (3S)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide, CITRATE ANION, GLUTAMIC ACID, ... | 著者 | Hald, H, Gajhede, M, Kastrup, J.S. | 登録日 | 2009-04-24 | 公開日 | 2009-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2. J.Mol.Biol., 391, 2009
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3H6V
| Crystal structure of the iGluR2 ligand-binding core (S1S2J-N754S) in complex with glutamate and NS5206 at 2.10 A resolution | 分子名称: | (3R)-3-cyclopentyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide, DIMETHYL SULFOXIDE, GLUTAMIC ACID, ... | 著者 | Hald, H, Gajhede, M, Kastrup, J.S. | 登録日 | 2009-04-24 | 公開日 | 2009-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2. J.Mol.Biol., 391, 2009
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2ANJ
| Crystal Structure of the Glur2 Ligand Binding Core (S1S2J-Y450W) Mutant in Complex With the Partial Agonist Kainic Acid at 2.1 A Resolution | 分子名称: | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2 | 著者 | Holm, M.M, Naur, P, Vestergaard, B, Geballe, M.T, Gajhede, M, Kastrup, J.S, Traynelis, S.F, Egebjerg, J. | 登録日 | 2005-08-11 | 公開日 | 2005-08-30 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A Binding Site Tyrosine Shapes Desensitization Kinetics and Agonist Potency at GluR2: a mutagenic, kinetic, and crystallographic study J.Biol.Chem., 280, 2005
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1NNP
| X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with (S)-ATPA at 1.9 A resolution. Crystallization without zinc ions. | 分子名称: | 3-(5-TERT-BUTYL-3-OXIDOISOXAZOL-4-YL)-L-ALANINATE, Glutamate receptor 2, SULFATE ION | 著者 | Lunn, M.L, Hogner, A, Stensbol, T.B, Gouaux, E, Egebjerg, J, Kastrup, J.S. | 登録日 | 2003-01-14 | 公開日 | 2003-03-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Three-Dimensional Structure of the Ligand-Binding
Core of GluR2 in Complex with the Agonist (S)-ATPA:
Implications for Receptor Subunit Selectivity. J.Med.Chem., 46, 2003
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4AGW
| Discovery of a small molecule type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRalpha, Kit, and Src kinases | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-{2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}-N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromet hyl)phenyl}benzamide, GLYCEROL, ... | 著者 | Weisberg, E, Choi, H.G, Seeliger, M, Gray, N, Griffin, J.D. | 登録日 | 2012-02-01 | 公開日 | 2012-02-15 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Discovery of a Small-Molecule Type II Inhibitor of Wild-Type and Gatekeeper Mutants of Bcr-Abl, Pdgfralpha, Kit, and Src Kinases: Novel Type II Inhibitor of Gatekeeper Mutants. Blood, 115, 2010
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1NNK
| X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with (S)-ATPA at 1.85 A resolution. Crystallization with zinc ions. | 分子名称: | 3-(5-TERT-BUTYL-3-OXIDOISOXAZOL-4-YL)-L-ALANINATE, CHLORIDE ION, Glutamate receptor 2, ... | 著者 | Lunn, M.-L, Hogner, A, Stensbol, T.B, Gouaux, E, Egebjerg, J, Kastrup, J.S. | 登録日 | 2003-01-14 | 公開日 | 2003-03-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Three-Dimensional Structure of the Ligand-Binding
Core of GluR2 in Complex with the Agonist (S)-ATPA:
Implications for Receptor Subunit Selectivity. J.Med.Chem., 46, 2003
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1MS7
| X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with (S)-Des-Me-AMPA at 1.97 A resolution, Crystallization in the presence of zinc acetate | 分子名称: | (S)-2-AMINO-3-(3-HYDROXY-ISOXAZOL-4-YL)PROPIONIC ACID, Glutamate receptor subunit 2, ZINC ION | 著者 | Kasper, C, Lunn, M.-L, Liljefors, T, Gouaux, E, Egebjerg, J, Kastrup, J.S. | 登録日 | 2002-09-19 | 公開日 | 2003-07-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | GluR2 ligand-binding core complexes: importance of the isoxazolol moiety and 5-substituent for the binding mode of AMPA-type agonists FEBS Lett., 531, 2002
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1P1U
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1P1O
| Crystal structure of the GluR2 ligand-binding core (S1S2J) mutant L650T in complex with quisqualate | 分子名称: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2, SULFATE ION | 著者 | Armstrong, N, Mayer, M.L, Gouaux, E. | 登録日 | 2003-04-13 | 公開日 | 2003-06-10 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic
adjustment of agonist-induced conformational changes. Proc.Natl.Acad.Sci.USA, 100, 2003
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2XG7
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3TDJ
| Crystal structure of the GluA2 ligand-binding domain (S1S2J-L483Y-N754S) in complex with glutamate and BPAM-97 at 1.95 A resolution | 分子名称: | 4-ethyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide, CHLORIDE ION, GLUTAMIC ACID, ... | 著者 | Krintel, C, Frydenvang, K, Gajhede, M, Kastrup, J.S. | 登録日 | 2011-08-11 | 公開日 | 2011-09-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2. Biochem.J., 441, 2012
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3TKD
| Crystal structure of the GluA2 ligand-binding domain (S1S2J-L483Y-N754S) in complex with glutamate and cyclothiazide at 1.45 A resolution | 分子名称: | CYCLOTHIAZIDE, GLUTAMATE RECEPTOR 2, GLUTAMIC ACID, ... | 著者 | Krintel, C, Frydenvang, K, Gajhede, M, Kastrup, J.S. | 登録日 | 2011-08-26 | 公開日 | 2011-09-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2. Biochem.J., 441, 2012
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1P1N
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6OON
| Human Argonaute4 bound to guide RNA | 分子名称: | Protein argonaute-4, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*UP*U)-3') | 著者 | Park, M.S, Brackbill, J.A, Nakanishi, K. | 登録日 | 2019-04-23 | 公開日 | 2019-07-31 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Multidomain Convergence of Argonaute during RISC Assembly Correlates with the Formation of Internal Water Clusters. Mol.Cell, 75, 2019
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2L11
| Solution NMR structure of the Cbx3 in complex with H3K9me3 peptide | 分子名称: | Chromobox protein homolog 3, Histone H3 | 著者 | Kaustov, L, Lemak, A, Fares, C, Gutmanas, A, Quang, H, Loppnau, P, Min, J, Edwards, A, Arrowsmith, C, Structural Genomics Consortium (SGC) | 登録日 | 2010-07-22 | 公開日 | 2010-08-04 | 最終更新日 | 2020-02-05 | 実験手法 | SOLUTION NMR | 主引用文献 | Recognition and specificity determinants of the human cbx chromodomains. J.Biol.Chem., 286, 2011
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2L1B
| Solution NMR structure of the chromobox protein Cbx7 with H3K27me3 | 分子名称: | Chromobox protein homolog 7, Histone H3 | 著者 | Kaustov, L, Lemak, A, Fares, C, Gutmanas, A, Muhandiram, R, Quang, H, Loppnau, P, Min, J, Edwards, A, Arrowsmith, C, Structural Genomics Consortium (SGC) | 登録日 | 2010-07-27 | 公開日 | 2010-08-25 | 最終更新日 | 2020-02-05 | 実験手法 | SOLUTION NMR | 主引用文献 | Recognition and specificity determinants of the human cbx chromodomains. J.Biol.Chem., 286, 2011
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6P72
| Crystal Structure of the Cedar henipavirus Attachment G Glycoprotein global domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Attachment glycoprotein, ... | 著者 | Xu, K, Nikolov, D.B, Xu, Y. | 登録日 | 2019-06-04 | 公開日 | 2019-09-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.283 Å) | 主引用文献 | Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus. Proc.Natl.Acad.Sci.USA, 116, 2019
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6P7S
| Crystal Structure of the Cedar henipavirus Attachment G Glycoprotein globular domain in complex with the receptor ephrin-B1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Attachment glycoprotein, ... | 著者 | Xu, K, Nikolov, D.B, Xu, Y. | 登録日 | 2019-06-06 | 公開日 | 2019-09-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | 主引用文献 | Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus. Proc.Natl.Acad.Sci.USA, 116, 2019
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6P7Y
| Crystal Structure of the Cedar henipavirus Attachment G Glycoprotein globular domain in complex with the receptor ephrin-B2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Attachment glycoprotein, ... | 著者 | Xu, K, Nikolov, D.B, Xu, Y. | 登録日 | 2019-06-06 | 公開日 | 2019-09-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.844 Å) | 主引用文献 | Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus. Proc.Natl.Acad.Sci.USA, 116, 2019
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2L12
| Solution NMR structure of the chromobox protein 7 with H3K9me3 | 分子名称: | Chromobox homolog 7, Histone H3 | 著者 | Kaustov, L, Lemak, A, Gutmanas, A, Fares, C, Quang, H, Loppnau, P, Min, J, Edwards, A, Arrowsmith, C, Structural Genomics Consortium (SGC) | 登録日 | 2010-07-22 | 公開日 | 2010-08-04 | 最終更新日 | 2020-02-05 | 実験手法 | SOLUTION NMR | 主引用文献 | Recognition and specificity determinants of the human cbx chromodomains. J.Biol.Chem., 286, 2011
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7TXZ
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7TY0
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