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4Z55
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Anaplastic lymphoma kinase catalytic domain complexed with pyrazolopyrimidine derivative of LDK378
分子名称: ALK tyrosine kinase receptor, GLYCEROL, N~6~-[5-methyl-4-(1-methylpiperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N~4~-[2-(propan-2-ylsulfonyl)phenyl]-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
著者Lee, C.C, Spraggon, G.
登録日2015-04-02
公開日2016-02-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Design and synthesis of novel selective anaplastic lymphoma kinase inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
5IMM
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BU of 5imm by Molmil
Nanobody targeting mouse Vsig4 in Spacegroup P212121
分子名称: Nanobody, Protein Vsig4
著者Wen, Y, Zheng, F.
登録日2016-03-06
公開日2017-01-11
最終更新日2017-07-05
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity
Immunobiology, 222, 2017
1QQL
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BU of 1qql by Molmil
THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7/1 CHIMERA
分子名称: FIBROBLAST GROWTH FACTOR 7/1 CHIMERA
著者Ye, S, Luo, Y, Pelletier, H, McKeehan, W.L.
登録日1999-06-07
公開日2000-01-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs.
Biochemistry, 40, 2001
1QQK
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THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7 (KERATINOCYTE GROWTH FACTOR)
分子名称: FIBROBLAST GROWTH FACTOR 7
著者Ye, S, Luo, Y, Pelletier, H, McKeehan, W.L.
登録日1999-06-07
公開日2000-01-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs.
Biochemistry, 40, 2001
5VK0
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BU of 5vk0 by Molmil
Crystal structure of human MDM2 in complex with a 12-mer lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, Lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI
著者Tolbert, W.D, Gohain, N, Pazgier, M.
登録日2017-04-20
公開日2018-04-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design.
Chem Sci, 10, 2019
5VK1
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Crystal structure of human MDM4 in complex with a 12-mer lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI
分子名称: Lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI, Protein Mdm4
著者Tolbert, W.D, Gohain, N, Pazgier, M.
登録日2017-04-20
公開日2018-04-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design.
Chem Sci, 10, 2019
6PLX
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BU of 6plx by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in SMA, desensitized state
分子名称: GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yu, J, Zhu, H, Gouaux, E.
登録日2019-07-01
公開日2021-01-06
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLZ
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BU of 6plz by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in SMA, closed state
分子名称: GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yu, J, Zhu, H, Gouaux, E.
登録日2019-07-01
公開日2021-01-06
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLY
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BU of 6ply by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in SMA, open state
分子名称: GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yu, J, Zhu, H, Gouaux, E.
登録日2019-07-01
公開日2021-01-06
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLR
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BU of 6plr by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with glycine in nanodisc, desensitized state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, Glycine receptor subunit alphaZ1, ...
著者Yu, J, Zhu, H, Gouaux, E.
登録日2019-07-01
公開日2021-01-06
最終更新日2021-07-21
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLO
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BU of 6plo by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor YGF mutant bound with GABA in SMA,open state
分子名称: GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yu, J, Zhu, H, Gouaux, E.
登録日2019-07-01
公開日2021-01-06
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLT
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BU of 6plt by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with taurine in nanodisc, closed state
分子名称: 2-AMINOETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1, ...
著者Yu, J, Zhu, H, Gouaux, E.
登録日2019-07-01
公開日2021-01-06
最終更新日2021-07-21
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLU
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BU of 6plu by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in nanodisc, desensitized state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, ...
著者Yu, J, Zhu, H, Gouaux, E.
登録日2019-07-01
公開日2021-01-06
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLS
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BU of 6pls by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with taurine in nanodisc, desensitized state
分子名称: 2-AMINOETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1, ...
著者Yu, J, Zhu, H, Gouaux, E.
登録日2019-07-01
公開日2021-01-06
最終更新日2021-07-21
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLV
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BU of 6plv by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in nanodisc, closed state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, ...
著者Yu, J, Zhu, H, Gouaux, E.
登録日2019-07-01
公開日2021-01-06
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLQ
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BU of 6plq by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor YGF mutant bound with GABA in SMA, super-open state
分子名称: GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yu, J, Zhu, H, Gouaux, E.
登録日2019-07-01
公開日2021-02-10
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM1
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BU of 6pm1 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, desensitized state
分子名称: 2-AMINOETHANESULFONIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yu, J, Zhu, H, Gouaux, E.
登録日2019-07-01
公開日2021-02-10
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM0
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BU of 6pm0 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, super-open state
分子名称: 2-AMINOETHANESULFONIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yu, J, Zhu, H, Gouaux, E.
登録日2019-07-01
公開日2021-02-10
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM4
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BU of 6pm4 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Glycine in SMA, super-open state
分子名称: GLYCINE, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yu, J, Zhu, H, Gouaux, E.
登録日2019-07-01
公開日2021-02-10
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM3
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BU of 6pm3 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, closed state
分子名称: 2-AMINOETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1
著者Yu, J, Zhu, H, Gouaux, E.
登録日2019-07-01
公開日2021-02-10
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM5
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BU of 6pm5 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Glycine in SMA, desensitized state
分子名称: GLYCINE, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yu, J, Zhu, H, Gouaux, E.
登録日2019-07-01
公開日2021-02-10
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM2
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BU of 6pm2 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, open state
分子名称: 2-AMINOETHANESULFONIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yu, J, Zhu, H, Gouaux, E.
登録日2019-07-01
公開日2021-02-10
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLP
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BU of 6plp by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor YGF mutant bound with GABA in SMA, desensitized state
分子名称: GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yu, J, Zhu, H, Gouaux, E.
登録日2019-07-01
公開日2021-02-10
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM6
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BU of 6pm6 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Glycine in SMA, open state
分子名称: GLYCINE, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yu, J, Zhu, H, Gouaux, E.
登録日2019-07-01
公開日2021-02-10
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLW
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BU of 6plw by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in SMA, super-open state
分子名称: GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yu, J, Zhu, H, Gouaux, E.
登録日2019-07-01
公開日2021-02-10
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021

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