6LU6
| Crystal structure of BPTF-BRD with ligand DCBPin5-2 bound | 分子名称: | 6-[1-[3-(dimethylamino)propyl]indol-5-yl]-2-methylsulfonyl-N-propyl-pyrimidin-4-amine, Nucleosome-remodeling factor subunit BPTF | 著者 | Lu, T, Lu, H.B, Wang, J, Lin, H, Lu, W, Luo, C. | 登録日 | 2020-01-26 | 公開日 | 2021-04-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.970063 Å) | 主引用文献 | Discovery and Optimization of Small-Molecule Inhibitors for the BPTF Bromodomains Proteins To Be Published
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1QQK
| THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7 (KERATINOCYTE GROWTH FACTOR) | 分子名称: | FIBROBLAST GROWTH FACTOR 7 | 著者 | Ye, S, Luo, Y, Pelletier, H, McKeehan, W.L. | 登録日 | 1999-06-07 | 公開日 | 2000-01-14 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs. Biochemistry, 40, 2001
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7F5D
| Crystal structure of BPTF-BRD with ligand DC-BPi-03 bound | 分子名称: | 6-(1H-indol-5-yl)-N-methyl-2-methylsulfonyl-pyrimidin-4-amine, Nucleosome-remodeling factor subunit BPTF | 著者 | Lu, T, Lu, H.B, Wang, J, Lin, H, Lu, W, Luo, C. | 登録日 | 2021-06-21 | 公開日 | 2022-06-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.57150865 Å) | 主引用文献 | Discovery and Optimization of Small-Molecule Inhibitors for the BPTF Bromodomains Proteins To Be Published
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7F5E
| Crystal structure of BPTF-BRD with ligand DC-BPi-11 bound | 分子名称: | N,N-dimethyl-3-[5-(2-methylsulfonyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)indol-1-yl]propan-1-amine, Nucleosome-remodeling factor subunit BPTF | 著者 | Lu, T, Lu, H.B, Wang, J, Lin, H, Lu, W, Luo, C. | 登録日 | 2021-06-21 | 公開日 | 2022-06-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.20017123 Å) | 主引用文献 | Discovery and Optimization of Small-Molecule Inhibitors for the BPTF Bromodomains Proteins To Be Published
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7F5C
| Crystal structure of BPTF-BRD with ligand DC-BPi-07 bound | 分子名称: | 6-[1-[3-(dimethylamino)propyl]indol-5-yl]-2-methylsulfonyl-N-propyl-pyrimidin-4-amine, Nucleosome-remodeling factor subunit BPTF | 著者 | Lu, T, Lu, H.B, Wang, J, Lin, H, Lu, W, Luo, C. | 登録日 | 2021-06-21 | 公開日 | 2022-06-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.65004492 Å) | 主引用文献 | Discovery and Optimization of Small-Molecule Inhibitors for the BPTF Bromodomains Proteins To Be Published
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3NCQ
| GlnK2 from Archaeoglobus fulgidus, ATP complex | 分子名称: | ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | 著者 | Helfmann, S, Lue, W, Litz, C, Andrade, S.L.A. | 登録日 | 2010-06-05 | 公開日 | 2010-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Cooperative binding of MgATP and MgADP in the trimeric P(II) protein GlnK2 from Archaeoglobus fulgidus. J.Mol.Biol., 402, 2010
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3NCR
| GlnK2 from Archaeoglubus fulgidus, ADP complex | 分子名称: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | 著者 | Helfmann, S, Lue, W, Litz, C, Andrade, S.L.A. | 登録日 | 2010-06-05 | 公開日 | 2010-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Cooperative binding of MgATP and MgADP in the trimeric P(II) protein GlnK2 from Archaeoglobus fulgidus. J.Mol.Biol., 402, 2010
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3NCP
| GlnK2 from Archaeoglobus fulgidus | 分子名称: | CHLORIDE ION, Nitrogen regulatory protein P-II (GlnB-2) | 著者 | Helfmann, S, Lue, W, Litz, C, Andrade, S.L.A. | 登録日 | 2010-06-05 | 公開日 | 2010-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Cooperative binding of MgATP and MgADP in the trimeric P(II) protein GlnK2 from Archaeoglobus fulgidus. J.Mol.Biol., 402, 2010
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4FNV
| Crystal Structure of Heparinase III | 分子名称: | Heparinase III protein, heparitin sulfate lyase | 著者 | Dong, W, Ye, S. | 登録日 | 2012-06-20 | 公開日 | 2012-11-28 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis of heparan sulfate-specific degradation by heparinase III. Protein Cell, 3, 2012
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5VK0
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5VK1
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4LB1
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4LBB
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4LB7
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4LBF
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7VD4
| Crystal structure of BPTF-BRD with ligand TP248 bound | 分子名称: | 6-[4-[3-(dimethylamino)propoxy]phenyl]-N-methyl-2-methylsulfonyl-pyrimidin-4-amine, Nucleosome-remodeling factor subunit BPTF | 著者 | Lu, T, Lu, H.B. | 登録日 | 2021-09-06 | 公開日 | 2022-09-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.85659146 Å) | 主引用文献 | Discovery of a highly potent CECR2 bromodomain inhibitor with 7H-pyrrolo[2,3-d] pyrimidine scaffold. Bioorg.Chem., 123, 2022
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6KX2
| Crystal structure of GDP bound RhoA protein | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Transforming protein RhoA | 著者 | Zhang, H, Luo, C. | 登録日 | 2019-09-09 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.454 Å) | 主引用文献 | Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion. Adv Sci, 7, 2020
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6KX3
| Crystal structure of RhoA protein with covalent inhibitor DC-Rhoin | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Transforming protein RhoA, prop-2-enyl (3R)-1,1-bis(oxidanylidene)-2,3-dihydro-1-benzothiophene-3-carboxylate | 著者 | Zhang, H, Luo, C. | 登録日 | 2019-09-09 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.981 Å) | 主引用文献 | Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion. Adv Sci, 7, 2020
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3T2G
| Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, Y229F variant with DHAP | 分子名称: | 1,3-DIHYDROXYACETONEPHOSPHATE, Fructose-1,6-bisphosphate aldolase/phosphatase, MAGNESIUM ION | 著者 | Du, J, Say, R, Lue, W, Fuchs, G, Einsle, O. | 登録日 | 2011-07-22 | 公開日 | 2011-10-26 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase. Nature, 478, 2011
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7QBA
| CryoEM structure of the ABC transporter NosDFY complexed with nitrous oxide reductase NosZ | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ... | 著者 | Zipfel, S, Mueller, C, Topitsch, A, Lutz, M, Zhang, L, Einsle, O. | 登録日 | 2021-11-18 | 公開日 | 2022-08-03 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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3T2D
| Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, FBP-bound form | 分子名称: | 1,6-di-O-phosphono-D-fructose, Fructose-1,6-bisphosphate aldolase/phosphatase, MAGNESIUM ION | 著者 | Du, J, Say, R, Lue, W, Fuchs, G, Einsle, O. | 登録日 | 2011-07-22 | 公開日 | 2011-10-26 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase. Nature, 478, 2011
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3T9Z
| A. fulgidus GlnK3, ligand-free | 分子名称: | CITRATE ANION, Nitrogen regulatory protein P-II (GlnB-3) | 著者 | Maier, S, Schleberger, P, Lue, W, Wacker, T, Pflueger, T, Litz, C, Andrade, S.L.A. | 登録日 | 2011-08-03 | 公開日 | 2011-10-26 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Mechanism of disruption of the Amt-GlnK complex by P(II)-mediated sensing of 2-oxoglutarate. Plos One, 6, 2011
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3TA1
| A. fulgidus GlnK3, MgADP complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Nitrogen regulatory protein P-II (GlnB-3) | 著者 | Maier, S, Schleberger, P, Lue, W, Wacker, T, Pflueger, T, Litz, C, Andrade, S.L.A. | 登録日 | 2011-08-03 | 公開日 | 2011-10-26 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanism of disruption of the Amt-GlnK complex by P(II)-mediated sensing of 2-oxoglutarate. Plos One, 6, 2011
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3TA0
| A. fulgidus GlnK3, MgATP complex | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Nitrogen regulatory protein P-II (GlnB-3) | 著者 | Maier, S, Schleberger, P, Lue, W, Wacker, T, Pflueger, T, Litz, C, Andrade, S.L.A. | 登録日 | 2011-08-03 | 公開日 | 2011-10-26 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Mechanism of disruption of the Amt-GlnK complex by P(II)-mediated sensing of 2-oxoglutarate. Plos One, 6, 2011
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3T2C
| Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, DHAP-bound form | 分子名称: | 1,3-DIHYDROXYACETONEPHOSPHATE, Fructose-1,6-bisphosphate aldolase/phosphatase, MAGNESIUM ION | 著者 | Du, J, Say, R, Lue, W, Fuchs, G, Einsle, O. | 登録日 | 2011-07-22 | 公開日 | 2011-10-26 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase. Nature, 478, 2011
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