8J7Y
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![BU of 8j7y by Molmil](/molmil-images/mine/8j7y) | Cryo-EM structure of hZnT7DeltaHis-loop-Fab complex in zinc-bound state, determined in outward-facing conformation | 分子名称: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | 著者 | Han, B.B, Inaba, K, Watanabe, S. | 登録日 | 2023-04-28 | 公開日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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3TY0
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![BU of 3ty0 by Molmil](/molmil-images/mine/3ty0) | Structure of PPARgamma ligand binding domain in complex with (R)-5-(3-((3-(6-methoxybenzo[d]isoxazol-3-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)methyl)phenyl)-5-methyloxazolidine-2,4-dione | 分子名称: | (5R)-5-(3-{[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl]methyl}phenyl)-5-methyl-1,3-oxazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma | 著者 | Soisson, S.M, Meinke, P.M, McKeever, B, Liu, W. | 登録日 | 2011-09-23 | 公開日 | 2011-11-23 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Benzimidazolones: a new class of selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) modulators. J.Med.Chem., 54, 2011
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7X1M
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![BU of 7x1m by Molmil](/molmil-images/mine/7x1m) | The complex structure of Omicron BA.1 RBD with BD604, S309,and S304 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BD-604 Fab heavy chain, BD-604 Fab light chain, ... | 著者 | Huang, M, Xie, Y.F, Qi, J.X. | 登録日 | 2022-02-24 | 公開日 | 2022-07-06 | 最終更新日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | 主引用文献 | Atlas of currently available human neutralizing antibodies against SARS-CoV-2 and escape by Omicron sub-variants BA.1/BA.1.1/BA.2/BA.3. Immunity, 55, 2022
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6A3V
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![BU of 6a3v by Molmil](/molmil-images/mine/6a3v) | Complex structure of human 4-1BB and 4-1BBL | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9 | 著者 | Li, Y, Zhang, C, Chai, Y, Qi, J, Tien, P, Gao, S, Gao, G.F. | 登録日 | 2018-06-17 | 公開日 | 2018-10-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.391 Å) | 主引用文献 | Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab. Cell Rep, 25, 2018
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6A3W
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![BU of 6a3w by Molmil](/molmil-images/mine/6a3w) | Complex structure of 4-1BB and utomilumab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor receptor superfamily member 9, utomilumab VH, ... | 著者 | Li, Y, Tan, S, Zhang, C, Chai, Y, Qi, J, Tien, P, Gao, S, Gao, G.F. | 登録日 | 2018-06-17 | 公開日 | 2018-10-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab. Cell Rep, 25, 2018
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4NW2
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![BU of 4nw2 by Molmil](/molmil-images/mine/4nw2) | Tandem chromodomains of human CHD1 in complex with Influenza virus NS1 C-terminal tail trimethylated at K229 | 分子名称: | Chromodomain-helicase-DNA-binding protein 1, GLYCEROL, Nonstructural protein 1, ... | 著者 | Qin, S, Tempel, W, Xu, C, El Bakkouri, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2013-12-05 | 公開日 | 2014-01-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1. Nat Commun, 5, 2014
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4O45
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![BU of 4o45 by Molmil](/molmil-images/mine/4o45) | WDR5 in complex with influenza NS1 C-terminal tail | 分子名称: | Nonstructural protein 1, UNKNOWN ATOM OR ION, WD repeat-containing protein 5 | 著者 | Qin, S, Xu, C, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2013-12-18 | 公開日 | 2014-04-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1. Nat Commun, 5, 2014
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4O42
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![BU of 4o42 by Molmil](/molmil-images/mine/4o42) | Tandem chromodomains of human CHD1 in complex with influenza NS1 C-terminal tail dimethylated at K229 | 分子名称: | Chromodomain-helicase-DNA-binding protein 1, GLYCEROL, Nonstructural protein 1, ... | 著者 | Qin, S, Xu, C, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2013-12-18 | 公開日 | 2014-04-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1. Nat Commun, 5, 2014
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6M24
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![BU of 6m24 by Molmil](/molmil-images/mine/6m24) | Uncommon structural features of rabbit MHC class I (RLA-A1) complexed with rabbit haemorrhagic disease virus (RHDV) derived peptide, VP60-2 | 分子名称: | Beta-2-microglobulin, RLA class I histocompatibility antigen, alpha chain 19-1, ... | 著者 | Zhang, Q.X, Liu, K.F, Yue, C, Zhang, D, Lu, D, Xiao, W.L, Liu, P.P, Zhao, Y.Z, Gao, G.L, Ding, C.M, Lyu, J.X, Liu, W.J. | 登録日 | 2020-02-26 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Strict Assembly Restriction of Peptides from Rabbit Hemorrhagic Disease Virus Presented by Rabbit Major Histocompatibility Complex Class I Molecule RLA-A1. J.Virol., 94, 2020
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6M2J
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![BU of 6m2j by Molmil](/molmil-images/mine/6m2j) | Uncommon structural features of rabbit MHC class I (RLA-A1) complexed with rabbit haemorrhagic disease virus (RHDV) derived peptide, VP60-1 | 分子名称: | Beta-2-microglobulin, RLA class I histocompatibility antigen, alpha chain 19-1, ... | 著者 | Zhang, Q.X, Liu, K.F, Yue, C, Zhang, D, Lu, D, Xiao, W.L, Liu, P.P, Zhao, Y.Z, Gao, G.L, Ding, C.M, Lyu, J.X, Liu, W.J. | 登録日 | 2020-02-27 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Strict Assembly Restriction of Peptides from Rabbit Hemorrhagic Disease Virus Presented by Rabbit Major Histocompatibility Complex Class I Molecule RLA-A1. J.Virol., 94, 2020
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6M2K
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![BU of 6m2k by Molmil](/molmil-images/mine/6m2k) | Uncommon structural features of rabbit MHC class I (RLA-A1) complexed with rabbit haemorrhagic disease virus (RHDV) derived peptide, VP60-10 | 分子名称: | Beta-2-microglobulin, RLA class I histocompatibility antigen, alpha chain 19-1, ... | 著者 | Zhang, Q.X, Liu, K.F, Yue, C, Zhang, D, Lu, D, Xiao, W.L, Liu, P.P, Zhao, Y.Z, Gao, G.L, Ding, C.M, Lyu, J.X, Liu, W.J. | 登録日 | 2020-02-27 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Strict Assembly Restriction of Peptides from Rabbit Hemorrhagic Disease Virus Presented by Rabbit Major Histocompatibility Complex Class I Molecule RLA-A1. J.Virol., 94, 2020
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7W9W
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![BU of 7w9w by Molmil](/molmil-images/mine/7w9w) | 2.02 angstrom cryo-EM structure of the pump-like channelrhodopsin ChRmine | 分子名称: | CHOLESTEROL, ChRmine, PALMITIC ACID, ... | 著者 | Kishi, K.E, Kim, Y, Fukuda, M, Yamashita, K, Deisseroth, K, Kato, H.E. | 登録日 | 2021-12-11 | 公開日 | 2022-02-02 | 最終更新日 | 2022-03-09 | 実験手法 | ELECTRON MICROSCOPY (2 Å) | 主引用文献 | Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine. Cell, 185, 2022
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3G51
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![BU of 3g51 by Molmil](/molmil-images/mine/3g51) | |
7RRC
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![BU of 7rrc by Molmil](/molmil-images/mine/7rrc) | IDO1 IN COMPLEX WITH COMPOUND 14 | 分子名称: | Indoleamine 2,3-dioxygenase 1, N-(4-fluorophenyl)-3-{4-[4-(hydroxymethyl)-6-(trifluoromethyl)pyridin-3-yl]phenyl}oxetane-3-carboxamide | 著者 | Lesburg, C.A. | 登録日 | 2021-08-09 | 公開日 | 2022-03-16 | 最終更新日 | 2022-05-11 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Oxetane Promise Delivered: Discovery of Long-Acting IDO1 Inhibitors Suitable for Q3W Oral or Parenteral Dosing. J.Med.Chem., 65, 2022
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7RRB
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![BU of 7rrb by Molmil](/molmil-images/mine/7rrb) | IDO1 IN COMPLEX WITH COMPOUND 9 | 分子名称: | 3-[4-(6-cyclopropylpyridin-3-yl)phenyl]-N-(4-fluorophenyl)oxetane-3-carboxamide, Indoleamine 2,3-dioxygenase 1 | 著者 | Lesburg, C.A. | 登録日 | 2021-08-09 | 公開日 | 2022-03-16 | 最終更新日 | 2022-05-11 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Oxetane Promise Delivered: Discovery of Long-Acting IDO1 Inhibitors Suitable for Q3W Oral or Parenteral Dosing. J.Med.Chem., 65, 2022
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7VLN
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![BU of 7vln by Molmil](/molmil-images/mine/7vln) | NSD2-PWWP1 domain bound with an imidazol-5-yl benzonitrile compound | 分子名称: | 4-[5-[4-(aminomethyl)-2,6-dimethoxy-phenyl]-3-methyl-imidazol-4-yl]benzenecarbonitrile, Histone-lysine N-methyltransferase NSD2 | 著者 | Cao, D.Y, Li, Y.L, Li, J, Xiong, B. | 登録日 | 2021-10-05 | 公開日 | 2022-07-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | Structure-Based Discovery of a Series of NSD2-PWWP1 Inhibitors. J.Med.Chem., 65, 2022
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7WBQ
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![BU of 7wbq by Molmil](/molmil-images/mine/7wbq) | |
7WBP
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![BU of 7wbp by Molmil](/molmil-images/mine/7wbp) | |
3N75
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![BU of 3n75 by Molmil](/molmil-images/mine/3n75) | X-ray Crystal Structure of the Escherichia coli Inducible Lysine Decarboxylase LdcI | 分子名称: | GLYCEROL, GUANOSINE-5',3'-TETRAPHOSPHATE, HEXAETHYLENE GLYCOL, ... | 著者 | Kanjee, U, Alexopoulos, E, Pai, E.F, Houry, W.A. | 登録日 | 2010-05-26 | 公開日 | 2011-02-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Linkage between the bacterial acid stress and stringent responses: the structure of the inducible lysine decarboxylase. Embo J., 30, 2011
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8UGZ
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![BU of 8ugz by Molmil](/molmil-images/mine/8ugz) | Crystal structure of Shewanella benthica Group 1 truncated hemoglobin C51S C71S variant | 分子名称: | CYANIDE ION, Group 1 truncated hemoglobin, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Schultz, T.D, Martinez, J.E, Siegler, M.A, Schlessman, J.L, Lecomte, J.T.J. | 登録日 | 2023-10-06 | 公開日 | 2024-04-03 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Heme d formation in a Shewanella benthica hemoglobin. J.Inorg.Biochem., 259, 2024
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8H5C
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![BU of 8h5c by Molmil](/molmil-images/mine/8h5c) | Structure of SARS-CoV-2 Omicron BA.2.75 RBD in complex with human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhao, Z.N, Bai, B, Liu, K.F, Qi, J.X, Gao, G.F. | 登録日 | 2022-10-12 | 公開日 | 2023-07-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants. Nat Commun, 14, 2023
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6J2I
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![BU of 6j2i by Molmil](/molmil-images/mine/6j2i) | Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with H17N10 influenza-like virus-derivrd peptide H17N10-NP | 分子名称: | Beta-2-microglobulin, H17N10-NP, Ptal-N*01:01 | 著者 | Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J. | 登録日 | 2019-01-01 | 公開日 | 2019-09-18 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats. Plos Biol., 17, 2019
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6J1V
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![BU of 6j1v by Molmil](/molmil-images/mine/6j1v) | The structure of HLA-A*3003/RT313 | 分子名称: | Beta-2-microglobulin, HLA-A*3003, RT313 | 著者 | Zhu, S.Y, Liu, K.F, Chai, Y, Ding, C.M, Lv, J.X, Gao, G.F, Lou, Y.L, Liu, W.J. | 登録日 | 2018-12-29 | 公開日 | 2019-09-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides. Front Immunol, 10, 2019
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6J2J
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![BU of 6j2j by Molmil](/molmil-images/mine/6j2j) | Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with MERS-CoV-derived peptide MERS-CoV-S3 | 分子名称: | Beta-2-microglobulin, MERS-CoV-S3, Ptal-N*01:01 | 著者 | Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J. | 登録日 | 2019-01-01 | 公開日 | 2019-09-18 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats. Plos Biol., 17, 2019
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6K7T
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![BU of 6k7t by Molmil](/molmil-images/mine/6k7t) | Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with Hendra virus-derived peptide HeV1--human beta-2 microglobulin | 分子名称: | Beta-2-microglobulin, HeV1, MHC class I antigen | 著者 | Lu, D, Liu, K.F, Zhang, D, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, F.G, Liu, W.J. | 登録日 | 2019-06-08 | 公開日 | 2019-11-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats. Plos Biol., 17, 2019
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