8HII
 
 | | The BRIL-SLC19A1/Fab/Nb ternary complex | | 分子名称: | BRIL-SLC19A1 chimera, anti-BRIL Fab heavy chain, anti-BRIL Fab light chain, ... | | 著者 | Zhang, Z, Dang, Y. | | 登録日 | 2022-11-20 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-01-11 | | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | | 主引用文献 | Molecular mechanism of substrate recognition by folate transporter SLC19A1.
Cell Discov, 8, 2022
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4HGT
 | | Crystal structure of ck1d with compound 13 | | 分子名称: | 2-{2-[(3,4-difluorophenoxy)methyl]-5-methoxypyridin-4-yl}-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one, Casein kinase I isoform delta | | 著者 | Huang, X. | | 登録日 | 2012-10-08 | | 公開日 | 2012-11-21 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure-Based Design of Potent and Selective CK1 gamma Inhibitors.
ACS Med Chem Lett, 3, 2012
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4E5P
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1JAB
 | | TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 T18S | | 分子名称: | PROTEIN (ANTIFREEZE PROTEIN TYPE III) | | 著者 | Graether, S.P, Deluca, C.I, Baardsnes, J, Hill, G.A, Davies, P.L, Jia, Z. | | 登録日 | 1999-01-24 | | 公開日 | 1999-04-29 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Quantitative and qualitative analysis of type III antifreeze protein structure and function.
J.Biol.Chem., 274, 1999
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4EBF
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4E5K
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4E5N
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4E5M
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3OK8
 | | I-BAR OF PinkBAR | | 分子名称: | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2, GLYCEROL | | 著者 | Boczkowska, M, Rebowski, G, Saarikangas, J, Lappalainen, P, Dominguez, R. | | 登録日 | 2010-08-24 | | 公開日 | 2011-07-13 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Pinkbar is an epithelial-specific BAR domain protein that generates planar membrane structures.
Nat.Struct.Mol.Biol., 18, 2011
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1KDE
 | | NORTH-ATLANTIC OCEAN POUT ANTIFREEZE PROTEIN TYPE III ISOFORM HPLC12 MUTANT, NMR, 22 STRUCTURES | | 分子名称: | ANTIFREEZE PROTEIN TYPE III ISOFORM HPLC12 MUTANT | | 著者 | Sonnichsen, F.D, Deluca, C.I, Davies, P.L, Sykes, B.D. | | 登録日 | 1996-07-08 | | 公開日 | 1997-04-21 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Refined solution structure of type III antifreeze protein: hydrophobic groups may be involved in the energetics of the protein-ice interaction.
Structure, 4, 1996
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1KDF
 | | NORTH-ATLANTIC OCEAN POUT ANTIFREEZE PROTEIN TYPE III ISOFORM HPLC12 MUTANT, NMR, MINIMIZED AVERAGE STRUCTURE | | 分子名称: | ANTIFREEZE PROTEIN | | 著者 | Sonnichsen, F.D, Deluca, C.I, Davies, P.L, Sykes, B.D. | | 登録日 | 1996-07-08 | | 公開日 | 1997-04-21 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Refined solution structure of type III antifreeze protein: hydrophobic groups may be involved in the energetics of the protein-ice interaction.
Structure, 4, 1996
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4HGL
 | | Crystal structure of ck1g3 with compound 1 | | 分子名称: | 2-[5-methoxy-2-(quinolin-3-yl)pyrimidin-4-yl]-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one, Casein kinase I isoform gamma-3, SULFATE ION | | 著者 | Huang, X. | | 登録日 | 2012-10-08 | | 公開日 | 2012-11-21 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure-Based Design of Potent and Selective CK1 gamma Inhibitors.
ACS Med Chem Lett, 3, 2012
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3EUO
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3F5O
 | | Crystal Structure of hTHEM2(undecan-2-one-CoA) complex | | 分子名称: | CHLORIDE ION, COENZYME A, HEXAETHYLENE GLYCOL, ... | | 著者 | Xu, H, Gong, W. | | 登録日 | 2008-11-04 | | 公開日 | 2009-08-18 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The mechanisms of human hotdog-fold thioesterase 2 (hTHEM2) substrate recognition and catalysis illuminated by a structure and function based analysis
Biochemistry, 48, 2009
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3CHT
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3EUQ
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3EUT
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6CFI
 | | Crystal structure of Rad4-Rad23 bound to a 6-4 photoproduct UV lesion | | 分子名称: | DNA (5'-D(*AP*TP*TP*GP*TP*AP*GP*CP*(T64)P*TP*GP*GP*AP*TP*GP*TP*TP*GP*AP*GP*TP*CP*A)-3'), DNA repair protein RAD4, DNA('-D(*TP*TP*GP*AP*CP*TP*CP*AP*AP*CP*AP*TP*CP*CP*AP*AP*AP*GP*CP*TP*AP*CP*AP*A)-'), ... | | 著者 | Min, J, Jeffrey, P.D. | | 登録日 | 2018-02-15 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.36241913 Å) | | 主引用文献 | Structure and mechanism of pyrimidine-pyrimidone (6-4) photoproduct recognition by the Rad4/XPC nucleotide excision repair complex.
Nucleic Acids Res., 47, 2019
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5B6I
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8XK5
 | | SNB1G11 Fab bound to SFTSV glycoprotein Gn | | 分子名称: | Envelopment polyprotein, mAb SNB1G11 Fab heavy chain, mAb SNB1G11 Fab light chain | | 著者 | Deng, Z. | | 登録日 | 2023-12-22 | | 公開日 | 2024-07-10 | | 最終更新日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | A broadly protective antibody targeting the glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection.
To Be Published
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8XK6
 | | S2A5 Fab bound to SFTSV glycoprotein Gn | | 分子名称: | Envelopment polyprotein, mAb S2A5 Fab heavy chain, mAb S2A5 Fab light chain | | 著者 | Deng, Z. | | 登録日 | 2023-12-22 | | 公開日 | 2024-07-10 | | 最終更新日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | A broadly protective antibody targeting the glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection.
To Be Published
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2RL5
 | | Crystal structure of the VEGFR2 kinase domain in complex with a 2,3-dihydro-1,4-benzoxazine inhibitor | | 分子名称: | N-(4-CHLOROPHENYL)-7-[(6,7-DIMETHOXYQUINOLIN-4-YL)OXY]-2,3-DIHYDRO-1,4-BENZOXAZINE-4-CARBOXAMIDE, Vascular endothelial growth factor receptor 2 | | 著者 | Whittington, D.A, Long, A.M, Rose, P, Zhao, H. | | 登録日 | 2007-10-18 | | 公開日 | 2008-04-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Novel 2,3-dihydro-1,4-benzoxazines as potent and orally bioavailable inhibitors of tumor-driven angiogenesis.
J.Med.Chem., 51, 2008
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3NLA
 | | NMR STRUCTURE OF THE N-TERMINAL DOMAIN WITH A LINKER PORTION OF ANTARCTIC EEL POUT ANTIFREEZE PROTEIN RD3, 40 STRUCTURES | | 分子名称: | ANTIFREEZE PROTEIN RD3 TYPE III | | 著者 | Miura, K, Ohgiya, S, Hoshino, T, Nemoto, N, Hikichi, K, Tsuda, S. | | 登録日 | 1998-02-24 | | 公開日 | 1999-02-23 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for the binding of a globular antifreeze protein to ice.
Nature, 384, 1996
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7QHE
 | | Human Butyrylcholinesterase in complex with (S)-1-(4-((naphthalen-1-yl)carbamoyl)benzyl)-N-(3-((1,2,3,4-tetrahydroacridin-9-yl)amino)propyl)piperidine-3-carboxamide | | 分子名称: | (3~{S})-1-[[4-(naphthalen-1-ylcarbamoyl)phenyl]methyl]-~{N}-[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]piperidine-3-carboxamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Brazzolotto, X, Jing, L, Zhan, P, Liu, X, Nachon, F. | | 登録日 | 2021-12-12 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Rapid discovery and crystallography study of highly potent and selective butylcholinesterase inhibitors based on oxime-containing libraries and conformational restriction strategies.
Bioorg.Chem., 134, 2023
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7QHD
 | | Human Butyrylcholinesterase in complex with (S)-1-(4-((2-(1H-indol-3-yl)ethyl)carbamoyl)benzyl)-N-(3-((1,2,3,4-tetrahydroacridin-9-yl)amino)propyl)piperidine-3-carboxamide | | 分子名称: | (3~{S})-1-[[4-[2-(1~{H}-indol-3-yl)ethylcarbamoyl]phenyl]methyl]-~{N}-[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]piperidine-3-carboxamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Brazzolotto, X, Jing, L, Zhan, P, Liu, X, Nachon, F. | | 登録日 | 2021-12-12 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Rapid discovery and crystallography study of highly potent and selective butylcholinesterase inhibitors based on oxime-containing libraries and conformational restriction strategies.
Bioorg.Chem., 134, 2023
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