4HGL
Crystal structure of ck1g3 with compound 1
Summary for 4HGL
Entry DOI | 10.2210/pdb4hgl/pdb |
Related | 4G16 4G17 4HGS 4HGT |
Descriptor | Casein kinase I isoform gamma-3, 2-[5-methoxy-2-(quinolin-3-yl)pyrimidin-4-yl]-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one, SULFATE ION, ... (4 entities in total) |
Functional Keywords | ck1g, kinase, inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q9Y6M4 |
Total number of polymer chains | 1 |
Total formula weight | 38936.68 |
Authors | Huang, X. (deposition date: 2012-10-08, release date: 2012-11-21, Last modification date: 2024-02-28) |
Primary citation | Huang, H.,Acquaviva, L.,Berry, V.,Bregman, H.,Chakka, N.,O'Connor, A.,DiMauro, E.F.,Dovey, J.,Epstein, O.,Grubinska, B.,Goldstein, J.,Gunaydin, H.,Hua, Z.,Huang, X.,Huang, L.,Human, J.,Long, A.,Newcomb, J.,Patel, V.F.,Saffran, D.,Serafino, R.,Schneider, S.,Strathdee, C.,Tang, J.,Turci, S.,White, R.,Yu, V.,Zhao, H.,Wilson, C.,Martin, M.W. Structure-Based Design of Potent and Selective CK1 gamma Inhibitors. ACS Med Chem Lett, 3:1059-1064, 2012 Cited by PubMed: 24900428DOI: 10.1021/ml300278f PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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