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4HGT

Crystal structure of ck1d with compound 13

Summary for 4HGT
Entry DOI10.2210/pdb4hgt/pdb
Related4HGL 4HGS
DescriptorCasein kinase I isoform delta, 2-{2-[(3,4-difluorophenoxy)methyl]-5-methoxypyridin-4-yl}-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one (3 entities in total)
Functional Keywordsck1d, kinase, inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P48730
Total number of polymer chains2
Total formula weight69472.05
Authors
Huang, X. (deposition date: 2012-10-08, release date: 2012-11-21, Last modification date: 2024-02-28)
Primary citationHuang, H.,Acquaviva, L.,Berry, V.,Bregman, H.,Chakka, N.,O'Connor, A.,DiMauro, E.F.,Dovey, J.,Epstein, O.,Grubinska, B.,Goldstein, J.,Gunaydin, H.,Hua, Z.,Huang, X.,Huang, L.,Human, J.,Long, A.,Newcomb, J.,Patel, V.F.,Saffran, D.,Serafino, R.,Schneider, S.,Strathdee, C.,Tang, J.,Turci, S.,White, R.,Yu, V.,Zhao, H.,Wilson, C.,Martin, M.W.
Structure-Based Design of Potent and Selective CK1 gamma Inhibitors.
ACS Med Chem Lett, 3:1059-1064, 2012
Cited by
PubMed: 24900428
DOI: 10.1021/ml300278f
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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