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6TBI
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BU of 6tbi by Molmil
Structure of a beta galactosidase with inhibitor
分子名称: (1S,2S,3S,6R)-4-(hydroxymethyl)-6-(octylamino)cyclohex-4-ene-1,2,3-triol, ACETATE ION, Beta-galactosidase, ...
著者Offen, W, Davies, G.
登録日2019-11-01
公開日2020-08-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C -5a-Substituted Derivatives of 4- epi -Isofagomine.
Molecules, 25, 2020
6TBJ
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BU of 6tbj by Molmil
Structure of a beta galactosidase with inhibitor
分子名称: 5-(dimethylamino)-~{N}-[6-[(2~{S},3~{R},4~{S},5~{R})-3-(hydroxymethyl)-4,5-bis(oxidanyl)piperidin-2-yl]hexyl]naphthalene-1-sulfonamide, Beta-galactosidase, putative, ...
著者Offen, W, Davies, G.
登録日2019-11-01
公開日2020-08-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C -5a-Substituted Derivatives of 4- epi -Isofagomine.
Molecules, 25, 2020
6TBH
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BU of 6tbh by Molmil
Structure of a beta galactosidase with inhibitor
分子名称: 5-[ethyl(methyl)amino]-~{N}-[6-[[(1~{S},2~{R},3~{S},4~{R})-2-(hydroxymethyl)-3,4-bis(oxidanyl)cyclopentyl]amino]hexyl]naphthalene-1-sulfonamide, ACETATE ION, Beta-galactosidase, ...
著者Offen, W, Davies, G.
登録日2019-11-01
公開日2020-08-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C -5a-Substituted Derivatives of 4- epi -Isofagomine.
Molecules, 25, 2020
6TBG
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BU of 6tbg by Molmil
Structure of a beta galactosidase with inhibitor
分子名称: 5-(dimethylamino)-~{N}-[6-[[(1~{R},2~{R},3~{S},4~{S},5~{S})-2-(hydroxymethyl)-3,4,5-tris(oxidanyl)cyclopentyl]amino]hexyl]naphthalene-1-sulfonamide, ACETATE ION, Beta-galactosidase, ...
著者Offen, W, Davies, G.
登録日2019-11-01
公開日2020-08-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C -5a-Substituted Derivatives of 4- epi -Isofagomine.
Molecules, 25, 2020
6TBK
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BU of 6tbk by Molmil
Structure of a beta galactosidase with inhibitor
分子名称: 5-(dimethylamino)-~{N}-[6-[(2~{R},3~{R},4~{S},5~{R})-3-(hydroxymethyl)-4,5-bis(oxidanyl)piperidin-2-yl]hexyl]naphthalene-1-sulfonamide, Beta-galactosidase, putative, ...
著者Offen, W, Davies, G.
登録日2019-11-01
公開日2020-08-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C -5a-Substituted Derivatives of 4- epi -Isofagomine.
Molecules, 25, 2020
6TBF
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BU of 6tbf by Molmil
Structure of a beta galactosidase with inhibitor
分子名称: (1~{S},2~{S},3~{S},4~{R},5~{R})-4-(hydroxymethyl)-5-(octylamino)cyclopentane-1,2,3-triol, ACETATE ION, Beta-galactosidase, ...
著者Offen, W, Davies, G.
登録日2019-11-01
公開日2020-08-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C -5a-Substituted Derivatives of 4- epi -Isofagomine.
Molecules, 25, 2020
5FCZ
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BU of 5fcz by Molmil
Streptomyces plicatus N-acetyl-beta-hexosaminidase in complex with Thio-NAglucal (TNX)
分子名称: 1,5-anhydro-2-deoxy-2-(ethanethioylamino)-D-arabino-hex-1-enitol, B-N-acetylhexosaminidase, CHLORIDE ION, ...
著者Vadlamani, G, Mark, B.L.
登録日2015-12-15
公開日2016-10-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献N-Acetyl glycals are tight-binding and environmentally insensitive inhibitors of hexosaminidases.
Chem.Commun.(Camb.), 52, 2016
8TCR
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BU of 8tcr by Molmil
Structure of glucose bound Alistipes sp. 3-Keto-beta-glucopyranoside-1,2-Lyase AL1
分子名称: COBALT (II) ION, MALONATE ION, Sugar phosphate isomerase, ...
著者Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J.
登録日2023-07-02
公開日2024-06-12
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献An alternative broad-specificity pathway for glycan breakdown in bacteria.
Nature, 631, 2024
8TCT
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BU of 8tct by Molmil
Structure of 3K-GlcH bound Bacteroides thetaiotaomicron 3-Keto-beta-glucopyranoside-1,2-Lyase BT1
分子名称: 1,5-anhydro-D-ribo-hex-3-ulose, COBALT (II) ION, PHOSPHATE ION, ...
著者Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J.
登録日2023-07-02
公開日2024-06-12
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献An alternative broad-specificity pathway for glycan breakdown in bacteria.
Nature, 631, 2024
8TDE
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BU of 8tde by Molmil
Structure of glucose bound Bacteroides thetaiotaomicron 3-Keto-2-hydroxy-glucal-hydratase BT2
分子名称: POTASSIUM ION, Probable secreted glycosyl hydrolase, alpha-D-glucopyranose
著者Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J.
登録日2023-07-02
公開日2024-06-12
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献An alternative broad-specificity pathway for glycan breakdown in bacteria.
Nature, 631, 2024
8TCD
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BU of 8tcd by Molmil
Structure of Alistipes sp. 3-Keto-beta-glucopyranoside-1,2-Lyase AL1
分子名称: ACETATE ION, COBALT (II) ION, GLYCEROL, ...
著者Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J.
登録日2023-06-30
公開日2024-06-12
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献An alternative broad-specificity pathway for glycan breakdown in bacteria.
Nature, 631, 2024
8TDA
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BU of 8tda by Molmil
Structure of Bacteroides thetaiotaomicron 3-Keto-2-hydroxy-glucal-hydratase BT2
分子名称: POTASSIUM ION, Probable secreted glycosyl hydrolase
著者Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J.
登録日2023-07-02
公開日2024-06-12
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献An alternative broad-specificity pathway for glycan breakdown in bacteria.
Nature, 631, 2024
8TDF
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BU of 8tdf by Molmil
Structure of Alistipes sp. Glucoside-3-dehydrogenase AL3
分子名称: Dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J.
登録日2023-07-02
公開日2024-06-12
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献An alternative broad-specificity pathway for glycan breakdown in bacteria.
Nature, 631, 2024
8TDI
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BU of 8tdi by Molmil
Structure of P2B11 Glucuronide-3-dehydrogenase
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, P2B11 Glucuronide-3-dehydrogenase, ...
著者Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J.
登録日2023-07-03
公開日2024-06-12
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献An alternative broad-specificity pathway for glycan breakdown in bacteria.
Nature, 631, 2024
5FD0
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BU of 5fd0 by Molmil
Streptomyces plicatus N-acetyl-beta-hexosaminidase in complex with NAGlucal
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, B-N-acetylhexosaminidase, GLYCEROL, ...
著者Vadlamani, G, Mark, B.L.
登録日2015-12-15
公開日2016-10-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献N-Acetyl glycals are tight-binding and environmentally insensitive inhibitors of hexosaminidases.
Chem.Commun.(Camb.), 52, 2016
5GPB
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BU of 5gpb by Molmil
COMPARISON OF THE BINDING OF GLUCOSE AND GLUCOSE-1-PHOSPHATE DERIVATIVES TO T-STATE GLYCOGEN PHOSPHORYLASE B
分子名称: (1S)-1,5-anhydro-1-(phosphonomethyl)-D-glucitol, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE, ...
著者Martin, J.L, Johnson, L.N.
登録日1990-06-04
公開日1992-10-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b.
Biochemistry, 29, 1990
8TCS
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BU of 8tcs by Molmil
Structure of trehalose bound Alistipes sp. 3-Keto-beta-glucopyranoside-1,2-Lyase AL1
分子名称: ACETATE ION, COBALT (II) ION, Xylose isomerase-like TIM barrel domain-containing protein, ...
著者Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J.
登録日2023-07-02
公開日2024-06-19
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献An alternative broad-specificity pathway for glycan breakdown in bacteria.
Nature, 631, 2024
8TDH
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BU of 8tdh by Molmil
Structure of trehalose bound Alistipes sp. Glucoside-3-dehydrogenase AL3
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Predicted dehydrogenases and related proteins, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose
著者Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J.
登録日2023-07-03
公開日2024-06-19
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献An alternative broad-specificity pathway for glycan breakdown in bacteria.
Nature, 631, 2024
1BVV
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BU of 1bvv by Molmil
SUGAR RING DISTORTION IN THE GLYCOSYL-ENZYME INTERMEDIATE OF A FAMILY G/11 XYLANASE
分子名称: ENDO-1,4-BETA-XYLANASE, beta-D-xylopyranose-(1-4)-1,5-anhydro-2-deoxy-2-fluoro-D-xylitol
著者Sidhu, G, Brayer, G.D.
登録日1998-09-18
公開日1999-06-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Sugar ring distortion in the glycosyl-enzyme intermediate of a family G/11 xylanase.
Biochemistry, 38, 1999
5KEZ
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BU of 5kez by Molmil
Selective and potent inhibition of the glycosidase human amylase by the short and extremely compact peptide piHA from mRNA display
分子名称: ACE-DTY-PRO-TYR-SER-CYS-TRP-VAL-ARG-HIS-NH2, CALCIUM ION, CHLORIDE ION, ...
著者Caner, S, Brayer, G.D.
登録日2016-06-10
公開日2017-03-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Rapid Discovery of Potent and Selective Glycosidase-Inhibiting De Novo Peptides.
Cell Chem Biol, 24, 2017
5L0T
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BU of 5l0t by Molmil
human POGLUT1 in complex with EGF(+) and UDP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Li, Z, Rini, J.M.
登録日2016-07-28
公開日2017-08-09
最終更新日2021-03-24
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Structural basis of Notch O-glucosylation and O-xylosylation by mammalian protein-O-glucosyltransferase 1 (POGLUT1).
Nat Commun, 8, 2017
5L0U
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BU of 5l0u by Molmil
human POGLUT1 in complex with EGF(+) and UDP-phosphono-glucose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, EGF(+), ...
著者Li, Z, Rini, J.M.
登録日2016-07-28
公開日2017-08-09
最終更新日2021-03-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of Notch O-glucosylation and O-xylosylation by mammalian protein-O-glucosyltransferase 1 (POGLUT1).
Nat Commun, 8, 2017
5L0V
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BU of 5l0v by Molmil
human POGLUT1 in complex with 2F-glucose modified EGF(+) and UDP
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-2-fluoro-beta-D-glucopyranose, ...
著者Li, Z, Rini, J.M.
登録日2016-07-28
公開日2017-08-09
最終更新日2021-03-24
実験手法X-RAY DIFFRACTION (1.305 Å)
主引用文献Structural basis of Notch O-glucosylation and O-xylosylation by mammalian protein-O-glucosyltransferase 1 (POGLUT1).
Nat Commun, 8, 2017
6GPB
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BU of 6gpb by Molmil
REFINED CRYSTAL STRUCTURE OF THE PHOSPHORYLASE-HEPTULOSE 2-PHOSPHATE-OLIGOSACCHARIDE-AMP COMPLEX
分子名称: 1-deoxy-2-O-phosphono-alpha-D-gluco-hept-2-ulopyranose, ADENOSINE MONOPHOSPHATE, GLYCOGEN PHOSPHORYLASE B, ...
著者Acharya, K.R, Johnson, L.N.
登録日1990-06-04
公開日1992-10-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Refined crystal structure of the phosphorylase-heptulose 2-phosphate-oligosaccharide-AMP complex.
J.Mol.Biol., 211, 1990
5L0S
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BU of 5l0s by Molmil
human POGLUT1 in complex with Factor VII EGF1 and UDP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Li, Z, Rini, J.M.
登録日2016-07-28
公開日2017-08-09
最終更新日2021-03-24
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural basis of Notch O-glucosylation and O-xylosylation by mammalian protein-O-glucosyltransferase 1 (POGLUT1).
Nat Commun, 8, 2017

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